Hypocalcemia in trauma patients receiving massive transfusion

Journal of Surgical Research

Volumn 202, Issue 1, 2016, Pages 182-187

  Giancarelli, Amanda ^a   Birrer, Kara L ^a   Alban, Rodrigo F ^a   Hobbs, Brandon P ^a   Liu Deryke, Xi ^a  

^a ORLANDO REGIONAL MEDICAL CENTER   (United States)

Author keywords

Blood coagulation; Blood transfusion; Calcium; Hypocalcemia; Resuscitation; Trauma

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; ANTICOAGULANT AGENT; CALCIUM; CALCIUM CHLORIDE; CALCIUM ION; CITRIC ACID; DESMOPRESSIN; LACTIC ACID; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TRANEXAMIC ACID; VITAMIN K GROUP;

ADULT; ARTICLE; BLOOD CLOTTING DISORDER; CALCIUM BLOOD LEVEL; CHELATION; CRYSTALLOID; DISEASE SEVERITY; FEMALE; HUMAN; HYPERCALCEMIA; HYPOCALCEMIA; INCIDENCE; INJURY; MAJOR CLINICAL STUDY; MALE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; TRANSFUSION; TREATMENT OUTCOME; ADOLESCENT; ADVERSE EFFECTS; AGED; BLOOD TRANSFUSION; COMPARATIVE STUDY; MIDDLE AGED; PROCEDURES; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; VERY ELDERLY; WOUNDS AND INJURIES; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD TRANSFUSION; FEMALE; HUMANS; HYPOCALCEMIA; INCIDENCE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; ROC CURVE; SEVERITY OF ILLNESS INDEX; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 84960955921     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2015.12.036     Document Type: Article

References (19)

1. J.L. Sperry, J.B. Ochoa, S.R. Gunn, and et al. An FFP: PRBC transfusion ratio ≥1:1.5 is associated with a lower risk of mortality after massive transfusion J Trauma 65 2008 986
2. O.L. Gunter Jr., B.K. Au, J.M. Isbell, N.T. Mowery, P.P. Young, and B.A. Cotton Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival J Trauma 65 2008 527
3. M. Maegele, R. Lefering, T. Paffrath, T. Tjardes, C. Simanski, and B. Bouillon Red-blood-cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiple injury: A retrospective analysis from the Trauma Registry of the Deutsche Gesellschaft fur Unfallchirurgie Vox Sang 95 2008 112
4. J.B. Holcomb, C.E. Wade, J.E. Michalek, and et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients Ann Surg 248 2008 447
5. J.B. MacLeod, M. Lynn, M.G. McKenney, S.M. Cohn, and M. Murtha Early coagulopathy predicts mortality in trauma J Trauma 55 2003 39
6. K. Brohi, J. Singh, M. Heron, and T. Coats Acute traumatic coagulopathy J Trauma 54 2003 1127
7. N. Cosgriff, E.E. Moore, A. Sauaia, M. Kenny-Moynihan, J. Burch, and B. Galloway Predicting life-threatening coagulopathy in the massively transfused trauma patient: hypothermia and acidosis revisited J Trauma 42 1997 May 857
8. J.R. Hess, K. Brohi, R.P. Dutton, and et al. The coagulopathy of trauma: A review of mechanisms J Trauma 65 2008 748
9. J. Elmer, S.R. Wilcox, and A.S. Raja Massive transfusion in traumatic shock J Emerg Med 44 2013 Apr 829
10. K.C. Sihler, and L.M. Napolitano Complications of massive transfusion Chest 137 2010 209
11. C.J. Cote, L.J. Drop, D.C. Hoaglin, A.L. Daniels, and E.T. Yound Ionized hypocalcemia after fresh frozen plasma administration to thermally injured children Anesth Analg 67 1988 152
12. H. Lier, H. Krep, S. Schroeder, and F. Stuber Preconditions of hemostasis in trauma: A review J Trauma 65 2008 951
13. M.D. Kraft, I.F. Btaiche, G.S. Sacks, and K.A. Kudsk Treatment of electrolyte disorders in adult patients in the intensive care unit Am J Health Syst Pharm 62 2005 1663
14. T. Steele, R. Kolamunnage-Dona, C. Downey, C.H. Toh, and I. Welters Assessment and clinical course of hypocalcemia in critical illness Crit Care 17 2013 R106
15. R.C. Kahn, D. Jascott, G.C. Carlon, O. Schweizer, W.S. Howland, and P.L. Goldiner Massive blood replacement: correlation of ionized calcium, citrate and hydrogen ion concentration Anesth Analg 58 1979 274
16. R.N. Dickerson, L.G. Morgan, A.D. Cauthen, and et al. Treatment of acute hypocalcemia in critically ill multiple-trauma patients JPEN J Parenter Enteral Nutr 29 2005 436
17. R.N. Dickerson, L.M. Morgan, M.A. Croce, G. Minard, and R.O. Brown Treatment of moderate to severe hypocalcemia in critically ill trauma patients JPEN J Parenter Enteral Nutr 31 2007 228
18. CRASH-2 trial collaborators Effect of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage: A randomized, placebo-controlled trial Lancet 376 2010 23
19. CRASH-2 trial collaborators The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trial Lancet 377 2011 1096