Ethanol production from lignocellulosic hydrolysates using engineered Saccharomyces cerevisiae harboring xylose isomerase-based pathway

Bioresource Technology

Volumn 209, Issue , 2016, Pages 290-296

  Ko, Ja Kyong ^a   Um, Youngsoon ^a   Woo, Han Min ^a   Kim, Kyoung Heon ^b   Lee, Sun Mi ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

Author keywords

Co fermentation; Ethanol; Lignocellulosic hydrolysate; Saccharomyces cerevisiae; Xylose isomerase

Indexed keywords

BIOETHANOL; FERMENTATION; GLUCOSE; SUGARS; YEAST;

BIO-ETHANOL PRODUCTION; COFERMENTATION; CONVERSION YIELD; ETHANOL PRODUCTION; LIGNOCELLULOSIC BIOMASS; LIGNOCELLULOSIC ETHANOLS; LIGNOCELLULOSIC HYDROLYSATES; XYLOSE ISOMERASE;

ETHANOL;

ALCOHOL; GLUCOSE; LIGNOCELLULOSE; XYLOSE; XYLOSE ISOMERASE; ISOMERASE; LIGNIN; WASTE;

BIOMASS; DECIDUOUS TREE; ETHANOL; FERMENTATION; GLUCOSE; STRAW; SUGAR;

ALCOHOL PRODUCTION; ARTICLE; CONTROLLED STUDY; FERMENTATION; GLUCOSE INTAKE; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; ANALYSIS; BIOMASS; CHEMISTRY; HYDROLYSIS; METABOLISM; OAK; ORYZA; PROCEDURES; WASTE; WOOD;

SACCHAROMYCES CEREVISIAE;

ALDOSE-KETOSE ISOMERASES; BIOMASS; ETHANOL; FERMENTATION; GLUCOSE; HYDROLYSIS; LIGNIN; METABOLIC ENGINEERING; ORYZA; QUERCUS; SACCHAROMYCES CEREVISIAE; WASTE PRODUCTS; WOOD; XYLOSE;

EID: 84960927374     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2016.02.124     Document Type: Article

References (32)

1. Almeida J.R.M., Modig T., Petersson A., Hähn-Hägerdal B., Lidén G., Gorwa-Grauslund M.F. Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae. J. Chem. Technol. Biotechnol. 2007, 82:340-349.
2. Casey E., Sedlak M., Ho N.W., Mosier N.S. Effect of acetic acid and pH on the cofermentation of glucose and xylose to ethanol by a genetically engineered strain of Saccharomyces cerevisiae. FEMS Yeast Res. 2010, 10:385-393.
3. Demeke M.M., Dietz H., Li Y., Foulquie-Moreno M.R., Mutturi S., Deprez S., Den Abt T., Bonini B.M., Liden G., Dumortier F., Verplaetse A., Boles E., Thevelein J.M. Development of a d-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering. Biotechnol. Biofuels 2013, 6:89.
4. Galbe M., Sassner P., Wingren A., Zacchi G. Process engineering economics of bioethanol production. Adv. Biochem. Eng. Biotechnol. 2007, 108:303-327.
5. Hasunuma T., Sanda T., Yamada R., Yoshimura K., Ishii J., Kondo A. Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae. Microb. Cell Fact. 2011, 10:2.
6. Hoyer K., Galbe M., Zacchi G. Production of fuel ethanol from softwood by simultaneous saccharification and fermentation at high dry matter content. J. Chem. Technol. Biotechnol. 2009, 84:570-577.
7. Jönsson L.J., Alriksson B., Nilvebrant N.O. Bioconversion of lignocellulose: inhibitors and detoxification. Biotechnol. Biofuels 2013, 6:16.
8. Kim S.R., Ha S.J., Wei N., Oh E.J., Jin Y.S. Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol. Trends Biotechnol. 2012, 30:274-282.
9. Kim S.R., Park Y.C., Jin Y.S., Seo J.H. Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism. Biotechnol. Adv. 2013, 31:851-861.
10. Klinke H.B., Thomsen A.B., Ahring B.K. Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass. Appl. Microbiol. Biotechnol. 2004, 66:10-26.
11. Ko J.K., Um Y., Park Y.C., Seo J.H., Kim K.H. Compounds inhibiting the bioconversion of hydrothermally pretreated lignocellulose. Appl. Microbiol. Biotechnol. 2015, 99:4201-4212.
12. Koppram R., Albers E., Olsson L. Evolutionary engineering strategies to enhance tolerance of xylose utilizing recombinant yeast to inhibitors derived from spruce biomass. Biotechnol. Biofuels 2012, 5:32.
13. Kumar R., Wyman C.E. Effect of xylanase supplementation of cellulase on digestion of corn stover solids prepared by leading pretreatment technologies. Bioresour. Technol. 2009, 100:4203-4213.
14. Kuyper M., Hartog M.M., Toirkens M.J., Almering M.J., Winkler A.A., van Dijken J.P., Pronk J.T. Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentation. FEMS Yeast Res. 2005, 5:399-409.
15. Larsson S., Quintana-Sainz A., Reimann A., Nilvebrant N.O., Jonsson L.J. Influence of lignocellulose-derived aromatic compounds on oxygen-limited growth and ethanolic fermentation by Saccharomyces cerevisiae. Appl. Biochem. Biotechnol. 2000, 84-86:617-632.
16. Larsson S., Reimann A., Nilvebrant N.-O., Jönsson L. Comparison of different methods for the detoxification of lignocellulose hydrolyzates of spruce. Appl. Biochem. Biotechnol. 1999, 77:91-103.
17. Lau M.W., Dale B.E. Cellulosic ethanol production from AFEX-treated corn stover using Saccharomyces cerevisiae 424A(LNH-ST). Proc. Nat. Acad. Sci. U.S.A. 2009, 106:1368-1373.
18. Lee S.M., Jellison T., Alper H.S. Directed evolution of xylose isomerase for improved xylose catabolism and fermentation in the yeast Saccharomyces cerevisiae. Appl. Environ. Microbiol. 2012, 78:5708-5716.
19. Lee S.M., Jellison T., Alper H.S. Systematic and evolutionary engineering of a xylose isomerase-based pathway in Saccharomyces cerevisiae for efficient conversion yields. Biotechnol. Biofuels 2014, 7:122.
20. Lu Y., Warner R., Sedlak M., Ho N., Mosier N.S. Comparison of glucose/xylose cofermentation of poplar hydrolysates processed by different pretreatment technologies. Biotechnol. Progr. 2009, 25:349-356.
21. Matsushika A., Nagashima A., Goshima T., Hoshino T. Fermentation of xylose causes inefficient metabolic state due to carbon/energy starvation and reduced glycolytic flux in recombinant industrial Saccharomyces cerevisiae. PLoS ONE 2013, 8:e69005.
22. Novy V., Krahulec S., Wegleiter M., Muller G., Longus K., Klimacek M., Nidetzky B. Process intensification through microbial strain evolution: mixed glucose-xylose fermentation in wheat straw hydrolyzates by three generations of recombinant Saccharomyces cerevisiae. Biotechnol. Biofuels 2014, 7:49.
23. Palmqvist E., Grage H., Meinander N.Q., Hahn-Hagerdal B. Main and interaction effects of acetic acid, furfural, and p-hydroxybenzoic acid on growth and ethanol productivity of yeasts. Biotechnol. Bioeng. 1999, 63:46-55.
24. Parreiras L.S., Breuer R.J., Avanasi Narasimhan R., Higbee A.J., La Reau A., Tremaine M., Qin L., Willis L.B., Bice B.D., Bonfert B.L., Pinhancos R.C., Balloon A.J., Uppugundla N., Liu T., Li C., Tanjore D., Ong I.M., Li H., Pohlmann E.L., Serate J., Withers S.T., Simmons B.A., Hodge D.B., Westphall M.S., Coon J.J., Dale B.E., Balan V., Keating D.H., Zhang Y., Landick R., Gasch A.P., Sato T.K. Engineering and two-stage evolution of a lignocellulosic hydrolysate-tolerant Saccharomyces cerevisiae strain for anaerobic fermentation of xylose from AFEX pretreated corn stover. PLoS ONE 2014, 9:e107499.
25. Romaní A., Pereira F., Johansson B., Domingues L. Metabolic engineering of Saccharomyces cerevisiae ethanol strains PE-2 and CAT-1 for efficient lignocellulosic fermentation. Bioresour. Technol. 2015, 179:150-158.
26. Sedlak M., Ho N.W. Production of ethanol from cellulosic biomass hydrolysates using genetically engineered Saccharomyces yeast capable of cofermenting glucose and xylose. Appl. Biochem. Biotechnol. 2004, 113-116:403-416.
27. Subtil T., Boles E. Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae. Biotechnol. Biofuels 2012, 5:14.
28. van Maris A.J., Winkler A.A., Kuyper M., de Laat W.T., van Dijken J.P., Pronk J.T. Development of efficient xylose fermentation in Saccharomyces cerevisiae: xylose isomerase as a key component. Adv. Biochem. Eng. Biotechnol. 2007, 108:179-204.
29. Van Vleet J.H., Jeffries T.W. Yeast metabolic engineering for hemicellulosic ethanol production. Curr. Opin. Biotechnol. 2009, 20:300-306.
30. Ximenes E., Kim Y., Mosier N., Dien B., Ladisch M. Inhibition of cellulases by phenols. Enzyme Microb. Technol. 2010, 46:170-176.
31. Young E., Lee S.-M., Alper H. Optimizing pentose utilization in yeast: the need for novel tools and approaches. Biotechnol. Biofuels 2010, 3:24.
32. Zaldivar J., Borges A., Johansson B., Smits H.P., Villas-Boas S.G., Nielsen J., Olsson L. Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 2002, 59:436-442.