메뉴 건너뛰기




Volumn 2, Issue 2, 2016, Pages 213-223

Chemically Cross-Linked Hybrid Nanogels of Alginate and PAMAM Dendrimers as Efficient Anticancer Drug Delivery Vehicles

Author keywords

apoptosis; cancer; dendrimers; epirubicin; nanogels

Indexed keywords

ALGINIC ACID; CYANAMIDE; DENDRIMER; EPIRUBICIN; NANOCARRIER; POLYAMIDOAMINE;

EID: 84960918072     PISSN: None     EISSN: 23739878     Source Type: Journal    
DOI: 10.1021/acsbiomaterials.5b00392     Document Type: Article
Times cited : (71)

References (52)
  • 1
    • 70349920791 scopus 로고    scopus 로고
    • Nanogels as pharmaceutical carriers: Finite networks of infinite capabilities
    • Kabanov, A. V.; Vinogradov, S. V. Nanogels as pharmaceutical carriers: finite networks of infinite capabilities Angew. Chem., Int. Ed. 2009, 48, 5418-5429 10.1002/anie.200900441
    • (2009) Angew. Chem., Int. Ed. , vol.48 , pp. 5418-5429
    • Kabanov, A.V.1    Vinogradov, S.V.2
  • 2
    • 84940488356 scopus 로고    scopus 로고
    • Biodegradable polymer nanogels for drug/nucleic acid delivery
    • Li, Y.; Maciel, D.; Rodrigues, J.; Shi, X.; Tomás, H. Biodegradable polymer nanogels for drug/nucleic acid delivery Chem. Rev. 2015, 115, 8564-8608 10.1021/cr500131f
    • (2015) Chem. Rev. , vol.115 , pp. 8564-8608
    • Li, Y.1    Maciel, D.2    Rodrigues, J.3    Shi, X.4    Tomás, H.5
  • 3
    • 34648828736 scopus 로고    scopus 로고
    • On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes
    • Oishi, M.; Sumitani, S.; Nagasaki, Y. On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes Bioconjugate Chem. 2007, 18, 1379-1382 10.1021/bc7002154
    • (2007) Bioconjugate Chem. , vol.18 , pp. 1379-1382
    • Oishi, M.1    Sumitani, S.2    Nagasaki, Y.3
  • 4
    • 77953496588 scopus 로고    scopus 로고
    • A nanogel for ratiometric fluorescent sensing of intracellular pH values
    • Peng, H. S.; Stolwijk, J. A.; Sun, L. N.; Wegener, J.; Wolfbeis, O. S. A nanogel for ratiometric fluorescent sensing of intracellular pH values Angew. Chem., Int. Ed. 2010, 49, 4246-4249 10.1002/anie.200906926
    • (2010) Angew. Chem., Int. Ed. , vol.49 , pp. 4246-4249
    • Peng, H.S.1    Stolwijk, J.A.2    Sun, L.N.3    Wegener, J.4    Wolfbeis, O.S.5
  • 6
    • 77049099292 scopus 로고    scopus 로고
    • In-situ immobilization of quantum dots in polysaccharide-based nanogels for integration of optical pH-sensing, tumor cell imaging, and drug delivery
    • Wu, W.; Aiello, M.; Zhou, T.; Berliner, A.; Banerjee, P.; Zhou, S. In-situ immobilization of quantum dots in polysaccharide-based nanogels for integration of optical pH-sensing, tumor cell imaging, and drug delivery Biomaterials 2010, 31, 3023-3031 10.1016/j.biomaterials.2010.01.011
    • (2010) Biomaterials , vol.31 , pp. 3023-3031
    • Wu, W.1    Aiello, M.2    Zhou, T.3    Berliner, A.4    Banerjee, P.5    Zhou, S.6
  • 8
    • 84867814700 scopus 로고    scopus 로고
    • Dual stimuli-responsive polymeric hollow nanogels designed as carriers for intracellular triggered drug release
    • Chiang, W. H.; Ho, V. T.; Huang, W. C.; Huang, Y. F.; Chern, C. S.; Chiu, H. C. Dual stimuli-responsive polymeric hollow nanogels designed as carriers for intracellular triggered drug release Langmuir 2012, 28, 15056-15064 10.1021/la302903v
    • (2012) Langmuir , vol.28 , pp. 15056-15064
    • Chiang, W.H.1    Ho, V.T.2    Huang, W.C.3    Huang, Y.F.4    Chern, C.S.5    Chiu, H.C.6
  • 9
    • 84893459278 scopus 로고    scopus 로고
    • Frontiers in the design and synthesis of advanced nanogels for nanomedicine
    • Liu, G.; An, Z. Frontiers in the design and synthesis of advanced nanogels for nanomedicine Polym. Chem. 2014, 5, 1559-1565 10.1039/C3PY01502E
    • (2014) Polym. Chem. , vol.5 , pp. 1559-1565
    • Liu, G.1    An, Z.2
  • 10
    • 77953633752 scopus 로고    scopus 로고
    • Surface-functionalizable polymer nanogels with facile hydrophobic guest encapsulation capabilities
    • Ryu, J. H.; Jiwpanich, S.; Chacko, R.; Bickerton, S.; Thayumanavan, S. Surface-functionalizable polymer nanogels with facile hydrophobic guest encapsulation capabilities J. Am. Chem. Soc. 2010, 132, 8246-8247 10.1021/ja102316a
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 8246-8247
    • Ryu, J.H.1    Jiwpanich, S.2    Chacko, R.3    Bickerton, S.4    Thayumanavan, S.5
  • 11
    • 0346094228 scopus 로고    scopus 로고
    • Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications
    • Berger, J.; Reist, M.; Mayer, J. M.; Felt, O.; Peppas, N. A.; Gurny, R. Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications Eur. J. Pharm. Biopharm. 2004, 57, 19-34 10.1016/S0939-6411(03)00161-9
    • (2004) Eur. J. Pharm. Biopharm. , vol.57 , pp. 19-34
    • Berger, J.1    Reist, M.2    Mayer, J.M.3    Felt, O.4    Peppas, N.A.5    Gurny, R.6
  • 12
    • 84926635098 scopus 로고    scopus 로고
    • Synthesis and characterization of a novel injectable alginate-collagen-hydroxyapatite hydrogel for bone tissue regeneration
    • Bendtsen, S. T.; Wei, M. Synthesis and characterization of a novel injectable alginate-collagen-hydroxyapatite hydrogel for bone tissue regeneration J. Mater. Chem. B 2015, 3, 3081-3090 10.1039/C5TB00072F
    • (2015) J. Mater. Chem. B , vol.3 , pp. 3081-3090
    • Bendtsen, S.T.1    Wei, M.2
  • 14
  • 15
    • 84910617929 scopus 로고    scopus 로고
    • Thermoresponsive gelatin nanogels
    • Gandhi, S. S.; Yan, H.; Kim, C. Thermoresponsive gelatin nanogels ACS Macro Lett. 2014, 3, 1210-1214 10.1021/mz500499q
    • (2014) ACS Macro Lett. , vol.3 , pp. 1210-1214
    • Gandhi, S.S.1    Yan, H.2    Kim, C.3
  • 16
    • 84880021921 scopus 로고    scopus 로고
    • Fluorescent dextran-based nanogels: Efficient imaging nanoprobes for adipose-derived stem cells
    • Zhou, S.; Dou, H.; Zhang, Z.; Sun, K.; Jin, Y.; Dai, T.; Zhouc, G.; Shen, Z. Fluorescent dextran-based nanogels: efficient imaging nanoprobes for adipose-derived stem cells Polym. Chem. 2013, 4, 4103-4112 10.1039/c3py00522d
    • (2013) Polym. Chem. , vol.4 , pp. 4103-4112
    • Zhou, S.1    Dou, H.2    Zhang, Z.3    Sun, K.4    Jin, Y.5    Dai, T.6    Zhouc, G.7    Shen, Z.8
  • 17
    • 84866405292 scopus 로고    scopus 로고
    • Hyaluronic acid/poly(β-amino ester) polymer nanogels for cancer-cell-specific NIR fluorescence switch
    • Park, H. S.; Lee, J. E.; Cho, M. Y.; Hong, J. H.; Cho, S. H.; Lim, Y. T. Hyaluronic acid/poly(β-amino ester) polymer nanogels for cancer-cell-specific NIR fluorescence switch Macromol. Rapid Commun. 2012, 33, 1549-1555 10.1002/marc.201200246
    • (2012) Macromol. Rapid Commun. , vol.33 , pp. 1549-1555
    • Park, H.S.1    Lee, J.E.2    Cho, M.Y.3    Hong, J.H.4    Cho, S.H.5    Lim, Y.T.6
  • 18
    • 84885598539 scopus 로고    scopus 로고
    • Natural polypeptide-based supramolecular nanogels for stable noncovalent encapsulation
    • Kim, K.; Bae, B.; Kang, Y. J.; Nam, J. M.; Kang, S.; Ryu, J. H. Natural polypeptide-based supramolecular nanogels for stable noncovalent encapsulation Biomacromolecules 2013, 14, 3515-3522 10.1021/bm400846h
    • (2013) Biomacromolecules , vol.14 , pp. 3515-3522
    • Kim, K.1    Bae, B.2    Kang, Y.J.3    Nam, J.M.4    Kang, S.5    Ryu, J.H.6
  • 19
    • 80455173988 scopus 로고    scopus 로고
    • Alginate: Properties and biomedical applications
    • Lee, K. Y.; Mooney, D. J. Alginate: properties and biomedical applications Prog. Polym. Sci. 2012, 37, 106-126 10.1016/j.progpolymsci.2011.06.003
    • (2012) Prog. Polym. Sci. , vol.37 , pp. 106-126
    • Lee, K.Y.1    Mooney, D.J.2
  • 20
    • 0015785598 scopus 로고
    • Biological interactions between polysaccharides and divalent cations: The egg-box model
    • Grant, G. T.; Morris, E. R.; Rees, D. A.; Smith, P. J. C.; Thom, D. Biological interactions between polysaccharides and divalent cations: the egg-box model FEBS Lett. 1973, 32, 195-198 10.1016/0014-5793(73)80770-7
    • (1973) FEBS Lett. , vol.32 , pp. 195-198
    • Grant, G.T.1    Morris, E.R.2    Rees, D.A.3    Smith, P.J.C.4    Thom, D.5
  • 21
    • 79959495125 scopus 로고    scopus 로고
    • pH sensitive Laponite/alginate hybrid hydrogels: Swelling behaviour and release mechanism
    • Li, Y.; Maciel, D.; Tomás, H.; Rodrigues, J.; Ma, H.; Shi, X. pH sensitive Laponite/alginate hybrid hydrogels: swelling behaviour and release mechanism Soft Matter 2011, 7, 6231-6238 10.1039/c1sm05345k
    • (2011) Soft Matter , vol.7 , pp. 6231-6238
    • Li, Y.1    Maciel, D.2    Tomás, H.3    Rodrigues, J.4    Ma, H.5    Shi, X.6
  • 22
    • 0032788329 scopus 로고    scopus 로고
    • Compressive and shear properties of alginate gel: Effects of sodium ions and alginate concentration
    • LeRoux, M. A.; Guilak, F.; Setton, L. A. Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration J. Biomed. Mater. Res. 1999, 47, 46-53 10.1002/(SICI)1097-4636(199910)47:1<46::AID-JBM6>3.0.CO;2-N
    • (1999) J. Biomed. Mater. Res. , vol.47 , pp. 46-53
    • LeRoux, M.A.1    Guilak, F.2    Setton, L.A.3
  • 25
    • 84923241651 scopus 로고    scopus 로고
    • Multicomponent 5-fluorouracil loaded PAMAM stabilized-silver nanocomposites synergistically induce apoptosis in human cancer cells
    • Matai, I.; Sachdev, A.; Gopinath, P. Multicomponent 5-fluorouracil loaded PAMAM stabilized-silver nanocomposites synergistically induce apoptosis in human cancer cells Biomater. Sci. 2015, 3, 457-468 10.1039/C4BM00360H
    • (2015) Biomater. Sci. , vol.3 , pp. 457-468
    • Matai, I.1    Sachdev, A.2    Gopinath, P.3
  • 26
    • 84930652762 scopus 로고    scopus 로고
    • Self-assembled hybrids of fluorescent carbon dots and PAMAM dendrimers for epirubicin delivery and intracellular imaging
    • Matai, I.; Sachdev, A.; Gopinath, P. Self-assembled hybrids of fluorescent carbon dots and PAMAM dendrimers for epirubicin delivery and intracellular imaging ACS Appl. Mater. Interfaces 2015, 7, 11423-11435 10.1021/acsami.5b02095
    • (2015) ACS Appl. Mater. Interfaces , vol.7 , pp. 11423-11435
    • Matai, I.1    Sachdev, A.2    Gopinath, P.3
  • 27
  • 30
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
    • Yuan, F.; Dellian, M.; Fukumura, D.; Leunig, M.; Berk, D. A.; Torchilin, V. P.; Jain, R. K. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size Cancer Res. 1995, 55, 3752-3756
    • (1995) Cancer Res. , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3    Leunig, M.4    Berk, D.A.5    Torchilin, V.P.6    Jain, R.K.7
  • 31
    • 0030833099 scopus 로고    scopus 로고
    • Determination of the cation content of alginate thin films by FTi.r. spectroscopy
    • Sartori, C.; Finch, D. S.; Ralph, B.; Gilding, K. Determination of the cation content of alginate thin films by FTi.r. spectroscopy Polymer 1997, 38, 43-51 10.1016/S0032-3861(96)00458-2
    • (1997) Polymer , vol.38 , pp. 43-51
    • Sartori, C.1    Finch, D.S.2    Ralph, B.3    Gilding, K.4
  • 32
    • 0033034332 scopus 로고    scopus 로고
    • Characteristics of sodium alginate membranes for the pervaporation dehydration of ethanol-water and isopropanol-water mixtures
    • Huang, R. Y. M.; Pal, R.; Moon, G. Y. Characteristics of sodium alginate membranes for the pervaporation dehydration of ethanol-water and isopropanol-water mixtures J. Membr. Sci. 1999, 160, 101-113 10.1016/S0376-7388(99)00071-X
    • (1999) J. Membr. Sci. , vol.160 , pp. 101-113
    • Huang, R.Y.M.1    Pal, R.2    Moon, G.Y.3
  • 34
    • 33646734274 scopus 로고    scopus 로고
    • Growth of multi-amine terminated poly(amidoamine) dendrimers on the surface of carbon nanotubes
    • Pan, B.; Cui, D.; Gao, F.; He, R. Growth of multi-amine terminated poly(amidoamine) dendrimers on the surface of carbon nanotubes Nanotechnology 2006, 17, 2483-2489 10.1088/0957-4484/17/10/008
    • (2006) Nanotechnology , vol.17 , pp. 2483-2489
    • Pan, B.1    Cui, D.2    Gao, F.3    He, R.4
  • 35
    • 0037039597 scopus 로고    scopus 로고
    • Controlled attachment of PAMAM dendrimers to solid surfaces
    • Fail, C. A.; Evenson, S. A.; Ward, L. J.; Schofield, W. C. E.; Badyal, J. P. S. Controlled attachment of PAMAM dendrimers to solid surfaces Langmuir 2002, 18, 264-268 10.1021/la0111598
    • (2002) Langmuir , vol.18 , pp. 264-268
    • Fail, C.A.1    Evenson, S.A.2    Ward, L.J.3    Schofield, W.C.E.4    Badyal, J.P.S.5
  • 36
    • 56749185962 scopus 로고    scopus 로고
    • Folate and folate-PEG-PAMAM dendrimers: Synthesis, characterization, and targeted anticancer drug delivery potential in tumor bearing mice
    • Singh, P.; Gupta, U.; Asthana, A.; Jain, N. K. Folate and folate-PEG-PAMAM dendrimers: synthesis, characterization, and targeted anticancer drug delivery potential in tumor bearing mice Bioconjugate Chem. 2008, 19, 2239-2252 10.1021/bc800125u
    • (2008) Bioconjugate Chem. , vol.19 , pp. 2239-2252
    • Singh, P.1    Gupta, U.2    Asthana, A.3    Jain, N.K.4
  • 37
    • 51649086595 scopus 로고    scopus 로고
    • Synthesis, characterization and swelling behaviors of sodium alginate-g-poly(acrylic acid)/sodium humate superabsorbent
    • Hua, S.; Wang, A. Synthesis, characterization and swelling behaviors of sodium alginate-g-poly(acrylic acid)/sodium humate superabsorbent Carbohydr. Polym. 2009, 75, 79-84 10.1016/j.carbpol.2008.06.013
    • (2009) Carbohydr. Polym. , vol.75 , pp. 79-84
    • Hua, S.1    Wang, A.2
  • 38
    • 84871643508 scopus 로고    scopus 로고
    • Development and evaluation of sodium alginate-polyacrylamide graft-co-polymer-based stomach targeted hydrogels of famotidine
    • Tripathi, R.; Mishra, B. Development and evaluation of sodium alginate-polyacrylamide graft-co-polymer-based stomach targeted hydrogels of famotidine AAPS PharmSciTech 2012, 13, 1091-1102 10.1208/s12249-012-9824-1
    • (2012) AAPS PharmSciTech , vol.13 , pp. 1091-1102
    • Tripathi, R.1    Mishra, B.2
  • 39
    • 28444456764 scopus 로고    scopus 로고
    • Synthesis and characterization of a novel alginate-poly(ethylene glycol) graft copolymer
    • Laurienzo, P.; Malinconico, M.; Motta, A.; Vicinanza, A. Synthesis and characterization of a novel alginate-poly(ethylene glycol) graft copolymer Carbohydr. Polym. 2005, 62, 274-282 10.1016/j.carbpol.2005.08.005
    • (2005) Carbohydr. Polym. , vol.62 , pp. 274-282
    • Laurienzo, P.1    Malinconico, M.2    Motta, A.3    Vicinanza, A.4
  • 40
    • 84927951751 scopus 로고    scopus 로고
    • L-Arginine grafted alginate hydrogel beads: A novel pH-sensitive system for specific protein delivery
    • Mohy Eldin, M. S.; Kamoun, E. A.; Sofan, M. A.; Elbayomi, S. M. L-Arginine grafted alginate hydrogel beads: A novel pH-sensitive system for specific protein delivery Arabian J. Chem. 2015, 8, 355-365 10.1016/j.arabjc.2014.01.007
    • (2015) Arabian J. Chem. , vol.8 , pp. 355-365
    • Mohy Eldin, M.S.1    Kamoun, E.A.2    Sofan, M.A.3    Elbayomi, S.M.4
  • 41
    • 9644275491 scopus 로고    scopus 로고
    • Physically crosslinked alginate/N,O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs
    • Lin, Y. H.; Liang, H. F.; Chung, C. K.; Chen, M. C.; Sung, H. W. Physically crosslinked alginate/N,O-carboxymethyl chitosan hydrogels with calcium for oral delivery of protein drugs Biomaterials 2005, 26, 2105-2113 10.1016/j.biomaterials.2004.06.011
    • (2005) Biomaterials , vol.26 , pp. 2105-2113
    • Lin, Y.H.1    Liang, H.F.2    Chung, C.K.3    Chen, M.C.4    Sung, H.W.5
  • 42
    • 25844527128 scopus 로고    scopus 로고
    • Quantifying Pb and Cd complexation by alginates and the role of metal binding on macromolecular aggregation
    • Lamelas, C.; Avaltroni, F.; Benedetti, M.; Wilkinson, K. J.; Slaveykova, V. I. Quantifying Pb and Cd complexation by alginates and the role of metal binding on macromolecular aggregation Biomacromolecules 2005, 6, 2756-2764 10.1021/bm050252y
    • (2005) Biomacromolecules , vol.6 , pp. 2756-2764
    • Lamelas, C.1    Avaltroni, F.2    Benedetti, M.3    Wilkinson, K.J.4    Slaveykova, V.I.5
  • 43
    • 33748714019 scopus 로고    scopus 로고
    • Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads
    • Pasparakis, G.; Bouropoulos, N. Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads Int. J. Pharm. 2006, 323, 34-42 10.1016/j.ijpharm.2006.05.054
    • (2006) Int. J. Pharm. , vol.323 , pp. 34-42
    • Pasparakis, G.1    Bouropoulos, N.2
  • 44
    • 84898677725 scopus 로고    scopus 로고
    • Increasing mechanical strength of gelatin hydrogels by divalent metal ion removal
    • Xing, Q.; Yates, K.; Vogt, C.; Qian, Z.; Frost, M. C.; Zhao, F. Increasing mechanical strength of gelatin hydrogels by divalent metal ion removal Sci. Rep. 2014, 4, 4706 10.1038/srep04706
    • (2014) Sci. Rep. , vol.4 , pp. 4706
    • Xing, Q.1    Yates, K.2    Vogt, C.3    Qian, Z.4    Frost, M.C.5    Zhao, F.6
  • 45
    • 0035099413 scopus 로고    scopus 로고
    • Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with mycobacterium avium subsp. paratuberculosis
    • Allen, S.; Sotos, J.; Sylte, M. J.; Czuprynski, C. J. Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with mycobacterium avium subsp. paratuberculosis Clin. Diagn. Lab. Immunol. 2001, 8, 460-464 10.1128/CDLI.8.2.460-464.2001
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , pp. 460-464
    • Allen, S.1    Sotos, J.2    Sylte, M.J.3    Czuprynski, C.J.4
  • 46
    • 84874697242 scopus 로고    scopus 로고
    • Epirubicin loaded to pre-polymerized poly(butyl cyanoacrylate) nanoparticles: Preparation and in vitro evaluation in human lung adenocarcinoma cells
    • Yordanov, G.; Evangelatov, A.; Skrobanska, R. Epirubicin loaded to pre-polymerized poly(butyl cyanoacrylate) nanoparticles: preparation and in vitro evaluation in human lung adenocarcinoma cells Colloids Surf., B 2013, 107, 115-123 10.1016/j.colsurfb.2013.02.002
    • (2013) Colloids Surf., B , vol.107 , pp. 115-123
    • Yordanov, G.1    Evangelatov, A.2    Skrobanska, R.3
  • 47
    • 77955488050 scopus 로고    scopus 로고
    • Conjugated polymers as multifunctional biomedical platforms: Anticancer activity and apoptosis imaging
    • Liu, L.; Yu, M.; Duan, X.; Wang, S. Conjugated polymers as multifunctional biomedical platforms: anticancer activity and apoptosis imaging J. Mater. Chem. 2010, 20, 6942-6947 10.1039/c0jm01078b
    • (2010) J. Mater. Chem. , vol.20 , pp. 6942-6947
    • Liu, L.1    Yu, M.2    Duan, X.3    Wang, S.4
  • 48
    • 34347215518 scopus 로고    scopus 로고
    • Analysis of apoptosis by propidium iodide staining and flow cytometry
    • Riccardi, C.; Nicoletti, I. Analysis of apoptosis by propidium iodide staining and flow cytometry Nat. Protoc. 2006, 1, 1458-1461 10.1038/nprot.2006.238
    • (2006) Nat. Protoc. , vol.1 , pp. 1458-1461
    • Riccardi, C.1    Nicoletti, I.2
  • 49
    • 0020473014 scopus 로고
    • A comparison of the lethal and kinetic effects of doxorubicin and 4′-epi-doxorubicin in vitro
    • Hill, B. T.; Whelan, R. D. A comparison of the lethal and kinetic effects of doxorubicin and 4′-epi-doxorubicin in vitro Tumori 1982, 68, 29-37
    • (1982) Tumori , vol.68 , pp. 29-37
    • Hill, B.T.1    Whelan, R.D.2
  • 50
    • 0026692045 scopus 로고
    • Dose dependence of the cytokinetic and cytotoxic effects of epirubicin in vitro
    • Bartkowiak, D.; Hemmer, J.; Röttinger, E. Dose dependence of the cytokinetic and cytotoxic effects of epirubicin in vitro Cancer Chemother. Pharmacol. 1992, 30, 189-192 10.1007/BF00686310
    • (1992) Cancer Chemother. Pharmacol. , vol.30 , pp. 189-192
    • Bartkowiak, D.1    Hemmer, J.2    Röttinger, E.3
  • 52
    • 17644370972 scopus 로고    scopus 로고
    • Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments
    • Rello, S.; Stockert, J. C.; Moreno, V.; Gámez, A.; Pacheco, M.; Juarranz, A.; Cañete, M.; Villanueva, A. Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments Apoptosis 2005, 10, 201-208 10.1007/s10495-005-6075-6
    • (2005) Apoptosis , vol.10 , pp. 201-208
    • Rello, S.1    Stockert, J.C.2    Moreno, V.3    Gámez, A.4    Pacheco, M.5    Juarranz, A.6    Cañete, M.7    Villanueva, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.