메뉴 건너뛰기




Volumn 38, Issue 8, 2015, Pages 1615-1621

Glycemic variability and diabetes complications: Does it matter? Simply put, there are better glycemic markers!

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOSYLATED HEMOGLOBIN; INSULIN; REACTIVE OXYGEN METABOLITE; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL;

EID: 84960880568     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc15-0099     Document Type: Article
Times cited : (109)

References (37)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulindependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulindependent diabetes mellitus. N Engl J Med 1993; 329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 2
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes UKPDS 33
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-853.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 3
    • 29144453326 scopus 로고    scopus 로고
    • Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes
    • Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group
    • Nathan DM, Cleary PA, Backlund JY, et al.; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353:2643-2653.
    • (2005) N Engl J Med , vol.353 , pp. 2643-2653
    • Nathan, D.M.1    Cleary, P.A.2    Backlund, J.Y.3
  • 4
    • 84920538565 scopus 로고    scopus 로고
    • Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality
    • Writing Group for the DCCT/EDIC Research Group
    • Orchard TJ, Nathan DM, Zinman B, et al.; Writing Group for the DCCT/EDIC Research Group. Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality. JAMA 2015;313:45-53.
    • (2015) JAMA , vol.313 , pp. 45-53
    • Orchard, T.J.1    Nathan, D.M.2    Zinman, B.3
  • 7
    • 77953245215 scopus 로고    scopus 로고
    • Beyond hemoglobin A1cdneed for additional markers of risk for diabetic microvascular complications
    • Hirsch IB, Brownlee M. Beyond hemoglobin A1cdneed for additional markers of risk for diabetic microvascular complications. JAMA 2010;303:2291-2292.
    • (2010) JAMA , vol.303 , pp. 2291-2292
    • Hirsch, I.B.1    Brownlee, M.2
  • 8
    • 43549115501 scopus 로고    scopus 로고
    • Characterizing glucose exposure for individuals with normal glucose tolerance using continuous glucose monitoring and ambulatory glucose profile analysis
    • Mazze RS, Strock E, Wesley D, et al. Characterizing glucose exposure for individuals with normal glucose tolerance using continuous glucose monitoring and ambulatory glucose profile analysis. Diabetes Technol Ther 2008;10:149- 159.
    • (2008) Diabetes, Technol Ther , vol.10 , pp. 149-159
    • Mazze, R.S.1    Strock, E.2    Wesley, D.3
  • 9
    • 79953800330 scopus 로고    scopus 로고
    • HbA1c and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: The A1C-Derived Average Glucose (ADAG) study
    • ADAG Study Group
    • Borg R, Kuenen JC, Carstensen B, et al.; ADAG Study Group. HbA1c and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: The A1C-Derived Average Glucose (ADAG) study. Diabetologia 2011;54:69-72.
    • (2011) Diabetologia , vol.54 , pp. 69-72
    • Borg, R.1    Kuenen, J.C.2    Carstensen, B.3
  • 10
    • 64749114318 scopus 로고    scopus 로고
    • Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial
    • Raz I, Wilson PW, Strojek K, et al. Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial. Diabetes Care 2009;32:381-386.
    • (2009) Diabetes, Care , vol.32 , pp. 381-386
    • Raz, I.1    Wilson, P.W.2    Strojek, K.3
  • 11
    • 79956191918 scopus 로고    scopus 로고
    • A decrease in glucose variability does not reduce cardiovascular event rates in type 2 diabetic patients after acute myocardial infarction: A reanalysis of the HEART2D study
    • Siegelaar SE, Kerr L, Jacober SJ, Devries JH. A decrease in glucose variability does not reduce cardiovascular event rates in type 2 diabetic patients after acute myocardial infarction: A reanalysis of the HEART2D study. Diabetes Care 2011;34:855-857.
    • (2011) Diabetes Care , vol.34 , pp. 855-857
    • Siegelaar, S.E.1    Kerr, L.2    Jacober, S.J.3    Devries, J.H.4
  • 12
    • 79956199963 scopus 로고    scopus 로고
    • Glycemic variability: Can we bridge the divide between controversies
    • Monnier L, Colette C. Glycemic variability: can we bridge the divide between controversies? Diabetes Care 2011;34:1058-1059.
    • (2011) ? Diabetes Care , vol.34 , pp. 1058-1059
    • Monnier, L.1    Colette, C.2
  • 13
    • 33746460818 scopus 로고    scopus 로고
    • The effect of glucose variability on the risk of microvascular complications in type 1 diabetes
    • Kilpatrick ES, Rigby AS, Atkin SL. The effect of glucose variability on the risk of microvascular complications in type 1 diabetes. Diabetes Care 2006;29:1486-1490.
    • (2006) Diabetes, Care , vol.29 , pp. 1486-1490
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 14
    • 42449121829 scopus 로고    scopus 로고
    • Effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trialdrevisited
    • DCCT/EDIC Research Group
    • Lachin JM, Genuth S, Nathan DM, Zinman B, Rutledge BN; DCCT/EDIC Research Group. Effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trialdrevisited. Diabetes 2008; 57:995-1001.
    • (2008) Diabetes , vol.57 , pp. 995-1001
    • Lachin, J.M.1    Genuth, S.2    Nathan, D.M.3    Zinman, B.4    Rutledge, B.N.5
  • 15
    • 84867089360 scopus 로고    scopus 로고
    • Rate of hypoglycemia in insulintreated patients with type 2 diabetes can be predicted from glycemic variability data
    • Qu Y, Jacober SJ, Zhang Q, Wolka LL, DeVries JH. Rate of hypoglycemia in insulintreated patients with type 2 diabetes can be predicted from glycemic variability data. Diabetes Technol Ther 2012;14:1008-1012.
    • (2012) Diabetes Technol Ther , vol.14 , pp. 1008-1012
    • Qu, Y.1    Jacober, S.J.2    Zhang, Q.3    Wolka, L.L.4    DeVries, J.H.5
  • 16
    • 84867256160 scopus 로고    scopus 로고
    • Comparative effectiveness of basal-bolus versus premix analog insulin on glycemic variability and patient-centered outcomes during insulin intensification in type 1 and type 2 diabetes: A randomized, controlled, crossover trial
    • Testa MA, Gill J, Su M, Turner RR, Blonde L, Simonson DC. Comparative effectiveness of basal-bolus versus premix analog insulin on glycemic variability and patient-centered outcomes during insulin intensification in type 1 and type 2 diabetes: A randomized, controlled, crossover trial. J Clin Endocrinol Metab 2012;97: 3504-3514.
    • (2012) J Clin Endocrinol, Metab , vol.97 , pp. 3504-3514
    • Testa, M.A.1    Gill, J.2    Su, M.3    Turner, R.R.4    Blonde, L.5    Simonson, D.C.6
  • 17
    • 70349249912 scopus 로고    scopus 로고
    • Interpretation of continuous glucose monitoring data: Glycemic variability and quality of glycemic control
    • Rodbard D. Interpretation of continuous glucose monitoring data: glycemic variability and quality of glycemic control. Diabetes Technol Ther 2009;11(Suppl. 1):S55-S67.
    • (2009) Diabetes Technol Ther , vol.11 , pp. S55-S67
    • Rodbard, D.1
  • 18
    • 84875132724 scopus 로고    scopus 로고
    • Recommendations for standardizing glucose reporting and analysis to optimize clinical decision making in diabetes: The Ambulatory Glucose Profile (AGP)
    • Bergenstal RM, Ahmann AJ, Bailey T, et al. Recommendations for standardizing glucose reporting and analysis to optimize clinical decision making in diabetes: The Ambulatory Glucose Profile (AGP). Diabetes Technol Ther 2013;15: 198-211.
    • (2013) Diabetes, Technol Ther , vol.15 , pp. 198-211
    • Bergenstal, R.M.1    Ahmann, A.J.2    Bailey, T.3
  • 19
    • 84963550777 scopus 로고    scopus 로고
    • Assessing the value of the Ambulatory Glucose Profile in clinical practice
    • Matthaei S. Assessing the value of the Ambulatory Glucose Profile in clinical practice. Br J Diabetes Vasc Dis 2014;14:148-152.
    • (2014) Br J Diabetes Vasc, Dis , vol.14 , pp. 148-152
    • Matthaei, S.1
  • 22
    • 84876560326 scopus 로고    scopus 로고
    • Glucose variability
    • Service FJ. Glucose variability. Diabetes 2013;62:1398-1404.
    • (2013) Diabetes , vol.62 , pp. 1398-1404
    • Service, F.J.1
  • 24
    • 67749084303 scopus 로고    scopus 로고
    • Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications and Pittsburgh Epidemiology of Diabetes Complications Experience (1983-2005)
    • Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
    • Nathan DM, Zinman B, Cleary PA, et al.; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group. Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications and Pittsburgh Epidemiology of Diabetes Complications Experience (1983-2005). Arch Intern Med 2009;169:1307-1316.
    • (2009) Arch Intern Med , vol.169 , pp. 1307-1316
    • Nathan, D.M.1    Zinman, B.2    Cleary, P.A.3
  • 26
    • 84898602820 scopus 로고    scopus 로고
    • Changes in diabetes-related complications in the United States, 1990-2010
    • Gregg EW, Li Y, Wang J, et al. Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med 2014;370: 1514-1523.
    • (2014) N Engl J Med , vol.370 , pp. 1514-1523
    • Gregg, E.W.1    Li, Y.2    Wang, J.3
  • 27
    • 84865523494 scopus 로고    scopus 로고
    • Severe hypoglycemia predicts mortality in diabetes
    • Cryer PE. Severe hypoglycemia predicts mortality in diabetes. Diabetes Care 2012;35: 1814-1816.
    • (2012) Diabetes Care , vol.35 , pp. 1814-1816
    • Cryer, P.E.1
  • 28
    • 0036020278 scopus 로고    scopus 로고
    • Hypoglycaemia: The limiting factor in the glycaemic management of type I and type II diabetes
    • Cryer PE. Hypoglycaemia: The limiting factor in the glycaemic management of type I and type II diabetes. Diabetologia 2002;45: 937-948.
    • (2002) Diabetologia , vol.45 , pp. 937-948
    • Cryer, P.E.1
  • 29
    • 84904128236 scopus 로고    scopus 로고
    • National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011
    • Lipska KJ, Ross JS, Wang Y, et al. National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011. JAMA Intern Med 2014; 174:1116-1124.
    • (2014) JAMA Intern Med , vol.174 , pp. 1116-1124
    • Lipska, K.J.1    Ross, J.S.2    Wang, Y.3
  • 30
    • 84881416448 scopus 로고    scopus 로고
    • Severe hypoglycaemia and cardiovascular disease: Systematic review and meta-analysis with bias analysis
    • Goto A, Arah OA, Goto M, Terauchi Y, Noda M. Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis. BMJ 2013;347:f4533.
    • (2013) BMJ , vol.347 , pp. f4533
    • Goto, A.1    Arah, O.A.2    Goto, M.3    Terauchi, Y.4    Noda, M.5
  • 31
    • 84897823556 scopus 로고    scopus 로고
    • Severe hypoglycemia identifies vulnerable patients with type 2 diabetes at risk for premature death and all-site cancer: The Hong Kong diabetes registry
    • Kong AP, Yang X, Luk A, et al. Severe hypoglycemia identifies vulnerable patients with type 2 diabetes at risk for premature death and all-site cancer: The Hong Kong diabetes registry. Diabetes Care 2014;37:1024-1031.
    • (2014) Diabetes Care , vol.37 , pp. 1024-1031
    • Kong, A.P.1    Yang, X.2    Luk, A.3
  • 32
    • 84879643475 scopus 로고    scopus 로고
    • Health ABC Study. Association between hypoglycemia and dementia in a biracial cohort of older adults with diabetes mellitus
    • Yaffe K, Falvey CM, Hamilton N, et al.; Health ABC Study. Association between hypoglycemia and dementia in a biracial cohort of older adults with diabetes mellitus. JAMA Intern Med 2013;173:1300-1306.
    • (2013) JAMA Intern Med , vol.173 , pp. 1300-1306
    • Yaffe, K.1    Falvey, C.M.2    Hamilton, N.3
  • 33
    • 84873918675 scopus 로고    scopus 로고
    • Medical resource use, disturbance of daily life and burden of hypoglycemia in insulin-treated patients with diabetes: Results from a European online survey
    • Willis WD, Diago-Cabezudo JI, Madec-Hily A, Aslam A. Medical resource use, disturbance of daily life and burden of hypoglycemia in insulin-treated patients with diabetes: results from a European online survey. Expert Rev Pharmacoecon Outcomes Res 2013;13: 123-130.
    • (2013) Expert Rev Pharmacoecon Outcomes Res , vol.13 , pp. 123-130
    • Willis, W.D.1    Diago-Cabezudo, J.I.2    Madec-Hily, A.3    Aslam, A.4
  • 34
    • 84903156652 scopus 로고    scopus 로고
    • Glycemic goals in diabetes: Tradeoff between glycemic control and iatrogenic hypoglycemia
    • Cryer PE. Glycemic goals in diabetes: Tradeoff between glycemic control and iatrogenic hypoglycemia. Diabetes 2014;63:2188-2195.
    • (2014) Diabetes , vol.63 , pp. 2188-2195
    • Cryer, P.E.1
  • 35
    • 84947945770 scopus 로고    scopus 로고
    • Evaluating quality of glycemic control: Graphical displays of hypo- And hyperglycemia, time in target range, and mean glucose
    • Rodbard D. Evaluating quality of glycemic control: graphical displays of hypo- And hyperglycemia, time in target range, and mean glucose. J Diabetes Sci Tech 2015;9:56-62.
    • (2015) J Diabetes Sci Tech , vol.9 , pp. 56-62
    • Rodbard, D.1
  • 36
    • 84969418852 scopus 로고    scopus 로고
    • Escaping the hemoglobin A1ccentric world in evaluating diabetes mellitus interventions
    • 19 February, [Epub ahead of print
    • Vigersky RA. Escaping the hemoglobin A1ccentric world in evaluating diabetes mellitus interventions. J Diabetes Sci Technol. 19 February 2015 [Epub ahead of print].
    • (2015) J Diabetes Sci Technol
    • Vigersky, R.A.1
  • 37
    • 84962430629 scopus 로고    scopus 로고
    • Design of FLAT-SUGAR: Randomized trial of prandial insulin versus prandial GLP-1 receptor agonist together with basal insulin and metformin for high-risk type 2 diabetes
    • The FLAT-SUGAR Trial Investigators
    • The FLAT-SUGAR Trial Investigators. Design of FLAT-SUGAR: randomized trial of prandial insulin versus prandial GLP-1 receptor agonist together with basal insulin and metformin for high-risk type 2 diabetes. Diabetes Care 2015; 38:1558-1566.
    • (2015) Diabetes Care , vol.38 , pp. 1558-1566


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.