Phosphate flame retardants and novel brominated flame retardants in home-produced eggs from an e-waste recycling region in China

Chemosphere

Volumn 150, Issue , 2016, Pages 545-550

  Zheng, Xiaobo ^a,b,c   Xu, Fuchao ^b   Luo, Xiaojun ^a   Mai, Bixian ^a   Covaci, Adrian ^b  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Dietary exposure; E waste recycling region; Flame retardants; Home produced eggs

Indexed keywords

ANIMALS; FLAME RETARDANTS; ISOMERS; ORGANIC POLLUTANTS; RECYCLING; WASTES;

BROMINATED FLAME RETARDANTS; DIETARY EXPOSURE; E-WASTE RECYCLING; ESTIMATED DAILY INTAKES; HIGHER FREQUENCIES; HOME-PRODUCED EGGS; POLYBROMINATED DIPHENYL ETHER (PBDES); TRIPHENYL PHOSPHATE;

ELECTRONIC WASTE;

2 ETHYLHEXYL 2,3,4,5 TETRABROMO BENZOATE; 2 ETHYLHEXYL 2,3,4,5 TETRABROMOBENZOATE; 2 ETHYLHEXYL DIPHENYL PHOSPHATE; 3,4,5,6 TETRABROMO PHTHALATE; ALBUMIN; BIS(2 ETHYLHEXYL) 3,4,5,6 TETRABROMO PHTHALATE; FLAME RETARDANT; ORGANOBROMINE DERIVATIVE; ORGANOPHOSPHATE; POLYBROMINATED DIPHENYL ETHER; TRIPHENYL PHOSPHATE; TRIS(1,3 DICHLOROISOPROPYL)PHOSPHATE; TRIS(CHLOROETHYL)PHOSPHATE; TRIS(CHLOROPROPYL)PHOSPHATE; UNCLASSIFIED DRUG; DIPHENYL ETHER DERIVATIVE; DUST; PHTHALIC ACID DERIVATIVE; POLLUTANT;

BIOACCUMULATION; CHEMICAL POLLUTANT; CONCENTRATION (COMPOSITION); EGG; PHOSPHATE; PHTHALATE; POULTRY; RECYCLING; WASTE TREATMENT;

ADULT; ARTICLE; CHILD; CHINA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIETARY INTAKE; EGG; EGG YOLK; ELECTRONIC WASTE; ENVIRONMENTAL EXPOSURE; HUMAN; NONHUMAN; RECYCLING; ANALYSIS; ANIMAL; CHICKEN; DUST; EATING; FOOD CONTAMINATION; POLLUTANT; RISK ASSESSMENT;

CHINA; GUANGDONG;

ADULT; ANIMALS; CHICKENS; CHILD; CHINA; DUST; EATING; EGGS; ELECTRONIC WASTE; ENVIRONMENTAL POLLUTANTS; FLAME RETARDANTS; FOOD CONTAMINATION; HALOGENATED DIPHENYL ETHERS; HUMANS; ORGANOPHOSPHATES; PHTHALIC ACIDS; RECYCLING; RISK ASSESSMENT;

EID: 84960809514     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2015.09.098     Document Type: Article

References (39)

1. Ballesteros-Gómez A., Van den Eede N., Covaci A. In vitro human metabolism of the flame retardant resorcinol bis(diphenylphosphate) (RDP). Environ. Sci. Technol. 2015, 49:3897-3904.
2. Bergman Å., Rydén A., Law R.J., de Boer J., Covaci A., Alaee M., Birnbaum L., Petreas M., Rose M., Sakai S., Van den Eede N., van der Veen I. A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicals. Environ. Int. 2012, 49:57-82.
3. Brandsma S.H., Leonards P.E., Leslie H.A., de Boer J. Tracing organophosphorus and brominated flame retardants and plasticizers in an estuarine food web. Sci. Total Environ. 2015, 505:22-31.
4. Canadian Environmental Protection Act (CEPA) Environmental Screening Assessment Report on Polybrominated Diphenyl Ethers (PBDEs) 1999.
5. Cequier E., Ionas A.C., Covaci A., Marcé R.M., Becher G., Thomsen C. Occurrence of a broad range of legacy and emerging flame retardants in indoor environments in Norway. Environ. Sci. Technol. 2014, 48:6827-6835.
6. Chen D., Letcher R.J., Chu S. Determination of non-halogenated, chlorinated and brominated organophosphate flame retardants in herring gull eggs based on liquid chromatography-tandem quadrupole mass spectrometry. J. Chromatogr. A 2012, 1220:169-174.
7. Chu S., Letcher R.J. Determination of organophosphate flame retardants and plasticizers in lipid-rich matrices using dispersive solid-phase extraction as a sample cleanup step and ultra-high performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometry. Anal. Chim. Acta 2015, 10.1016/j.aca.2015.05.024.
8. Covaci A., Harrad S., Abdallah M.A.E., Ali N., Law R.J., Herzke D., de Wit C.A. Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour. Environ. Int. 2011, 37:532-556.
9. Covaci A., Roosens L., Dirtu A.C., Waegeneers N., Van Overmeire I., Neels H., Goeyens L. Brominated flame retardants in Belgian home-produced eggs: levels and contamination sources. Sci. Total Environ. 2009, 407:4387-4396.
10. Davis E.F., Stapleton H.M. Photodegradation pathways of nonabrominated diphenyl ethers, 2-Ethylhexyltetrabromobenzoate and di(2-ethylhexyl)tetrabromophthalate: identifying potential markers of photodegradation. Environ. Sci. Technol. 2009, 43:5739-5746.
11. Domingo J.L. Health risks of human exposure to chemical contaminants through egg consumption: a review. Food Res. Int. 2014, 56:159-165.
12. European Court of Justice 2008-04-01, Case C-14/06, 2008.
13. Fang M., Stapleton H.M. Evaluating the bioaccessibility of flame retardants in house dust using an in vitro tenax bead-assisted sorptive physiologically based method. Environ. Sci. Technol. 2014, 48:13323-13330.
14. Farhat A., Crump D., Porter E., Chiu S., Letcher R.J., Su G., Kennedy S.W. Time-dependent effects of the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on mrna expression, in vitro and in ovo, reveal optimal sampling times for rapidly metabolized compounds. Environ. Toxicol. Chem. 2014, 33:2842-2849.
15. Greaves A.K., Letcher R.J. Comparative body compartment composition and in ovo transfer of organophosphate flame retardants in North American Great Lakes herring gulls. Environ. Sci. Technol. 2014, 48:7942-7950.
16. Gobas F., Kelly B.C., Arnot J.A. Quantitative structure activity relationships for predicting the bioaccumulation of POPs in terrestrial food-webs. Qsar Comb. Sci. 2003, 22:329-336.
17. Kelly B.C., Ikonomou M.G., Blair J.D., Morin A.E., Gobas F. Food web-specific biomagnification of persistent organic pollutants. Science 2007, 317:236-239.
18. Kim J.W., Isobe T., Chang K.H., Amano A., Maneja R.H., Zamora P.B., Siringan F.P., Tanabe S. Levels and distribution of organophosphorus flame retardants and plasticizers in fishes from Manila Bay, the Philippines. Environ. Pollut. 2011, 159:3653-3659.
19. Kim J.W., Isobe T., Muto M., Tue N.M., Katsura K., Malarvannan G., Sudaryanto A., Chang K.H., Prudente M., Viet P.H., Takahashi S., Tanabe S. Organophosphorus flame retardants (PFRs) in human breast milk from several Asian countries. Chemosphere 2014, 116:91-97.
20. Kim J.W., Ramaswamy B.R., Chang K.H., Isobe T., Tanabe S. Multi residue analytical method for the determination of antimicrobials, preservatives, benzotriazole UV stabilizers, flame retardants and plasticizers in fish using ultra high performance liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. A 2011, 1218:3511-3520.
21. Labunska I., Harrad S., Santillo D., Johnston P., Yun L. Domestic duck eggs: an important pathway of human exposure to PBDEs around e-waste and scrap metal processing areas in Eastern China. Environ. Sci. Technol. 2013, 47:9258-9266.
22. Labunska I., Abdallah M.A.E., Eulaers I., Covaci A., Tao F., Wang M., Santillo D., Johnston P., Harrad S. Human dietary intake of organohalogen contaminants at e-waste recycling sites in Eastern China. Environ. Int. 2015, 74:209-220.
23. Liu H., Hu Y., Luo P., Bao L., Qiu J., Leung L.M.Y., Zeng E.Y. Occurrence of halogenated flame retardants in sediment off an urbanized coastal zone: association with urbanization and industrialization. Environ. Sci. Technol. 2014, 48:8465-8473.
24. Ma W., Deng F., Xu Y., Xu H., Nie S., Li J., Deng H., Li H. The study on dietary intake and nutritional status of residents in Guangdong Province, China. South China J. Prev. Med. 2005, 31:1-5. (in Chinese).
25. Malarvannan G., Belpaire C., Geeraerts C., Eulaers I., Neels H., Covaci A. Organophosphorus flame retardants in the European eel in Flanders, Belgium: occurrence, fate and human health risk. Environ. Res. 2015, 140:604-610.
26. Rawn D.F.K., Sadler A., Quade S.C., Sun W.F., Lau B.P.Y., Kosarac I., Hayward S., Ryan J.J. Brominated flame retardants in Canadian chicken egg yolks. Food Addit. Contam. A 2011, 28:807-815.
27. Roberts S.C., Macaulay L.J., Stapleton H.M. In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (BEH-TEBP) in human and rat tissues. Chem. Res. Toxicol. 2012, 25:1435-1441.
28. Song Q., Li J. A systematic review of the human body burden of e-waste exposure in China. Environ. Int. 2014, 68:82-93.
29. Stapleton H.M., Allen J.G., Kelly S.M., Konstantinov A., Klosterhaus S., Watkins D., Mcclean M.D., Webster T.F. Alternate and new brominated flame retardants detected in U.S. house dust. Environ. Sci. Technol. 2008, 42:6910-6916.
30. Sundkvist A.M., Olofsson U., Haglund P. Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk. J. Environ. Monit. 2010, 12:943-951.
31. United Nations Environment Programme (UNEP) Stockholm Convention Text and Annexes as Amended in 2009 2009, Available at:, (accessed May 2015). http://chm.pops.int/Convention/tabid/54/language/en-US/Default.aspx#convtext.
32. Van den Eede N., Maho W., Erratico C., Neels H., Covaci A. First insights in the metabolism of phosphate flame retardants and plasticizers using human liver fractions. Toxicol. Lett. 2013, 223:9-15.
33. Van den Eede N., Heffernan A.L., Aylward L.L., Hobson P., Neels H., Mueller J.F. Age as a determinant of phosphate flame retardant exposure of the Australian population and identification of novel urinary PFR metabolites. Environ. Int. 2014, 74:1-8.
34. Van den Eede N., Erratico C., Exarchou V., Maho W., Neels H., Covaci A. In vitro biotransformation of tris(2-butoxyethyl) phosphate (TBOEP) in human liver and serum. Toxicol. Appl. Pharmacol. 2015, 284:246-253.
35. van der Veen I., de Boer J. Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis. Chemosphere 2012, 88:1119-1153.
36. Wei G.L., Li D.Q., Zhuo M.N., Liao Y.S., Xie Z.Y., Guo T.L., Li J.J., Zhang S.Y., Liang Z.Q. Organophosphorus flame retardants and plasticizers: sources, occurrence, toxicity and human exposure. Environ. Pollut. 2015, 196:29-46.
37. Xu F., García-Bermejo Á., Malarvannan, Gómara B., Neels H., Covaci A. Multi-contaminant analysis of organophosphate and halogenated flame retardants in food matrices using ultrasonication and vacuum assisted extraction, multi-stage cleanup and gas chromatography-mass spectrometry. J. Chromatogr. A 2015, 1404:33-41.
38. Zheng X.B., Wu J.P., Luo X.J., Zeng Y.H., She Y.Z., Mai B.X. Halogenated flame retardants in home-produced eggs from an electronic waste recycling region in South China: levels, composition profiles, and human dietary exposure assessment. Environ. Int. 2012, 45:122-128.
39. Zheng X.B., Xu F.C., Chen K.H., Zeng Y.H., Luo X.J., Chen S.J., Mai B.X., Covaci A. Flame retardants and organochlorines in indoor dust from several e-waste recycling sites in South China: composition variations and implications for human exposure. Environ. Int. 2015, 78:1-7.