Endogenous or exogenous antioxidants vs. pro-oxidants in macrophage atherogenicity

Current Opinion in Lipidology

Volumn 27, Issue 2, 2016, Pages 204-206

  Rom, Oren ^a   Aviram, Michael ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; APOLIPOPROTEIN E; CIGARETTE SMOKE; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR; OXIDIZING AGENT; POMEGRANATE EXTRACT; PRO OXIDANT; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; REACTIVE OXYGEN METABOLITE;

ATHEROGENESIS; ATHEROSCLEROSIS; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; FOAM CELL; HUMAN; LIPID METABOLISM; MACROPHAGE; NONHUMAN; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; HUMANS; MACROPHAGES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84960348922     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0000000000000287     Document Type: Note

References (11)

1. Rosenblat M, Volkova N, Aviram M. Selective oxidative stress and cholesterol metabolism in lipid-metabolizing cell classes: Distinct regulatory roles for prooxidants and antioxidants. Biofactors 2015; 41: 273-288
2. Rosenblat M, Volkova N, Aviram M. HDL3 stimulates paraoxonase 1 antiatherogenic catalytic and biological activities in a macrophage model system: in vivo and in vitro studies. Biofactors 2014; 40: 536-545
3. Hamoud S, Hayek T, Volkova N, et al. Pomegranate extract (POMx) decreases the atherogenicity of serum and of human monocyte-derived macrophages (HMDM) in simvastatin-treated hypercholesterolemic patients: a doubleblinded, placebo-controlled, randomized, prospective pilot study. Atherosclerosis 2014; 232: 204-210
4. Yang X, Yao H, Chen Y, et al. Inhibition of glutathione production induces macrophage CD36 expression and enhances cellular-oxidized low density lipoprotein (oxLDL) uptake. J Biol Chem 2015; 290: 21788-21799
5. Rosenblat M, Volkova N, Khatib S, et al. Reduced glutathione increases quercetin stimulatory effects on HDL- or apoA1-mediated cholesterol efflux from J774A.1 macrophages. Free Radic Res 2014; 48: 1462-1472
6. Madrigal-Matute J, Fernandez-Laso V, Sastre C, et al. TWEAK/Fn14 interaction promotes oxidative stress through NADPH oxidase activation in macrophages. Cardiovasc Res 2015; 108: 139-147
7. Rao X, Zhong J, Maiseyeu A, et al. CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure. Circ Res 2014; 115: 770-780
8. Petrick L, Rosenblat M, Aviram M. In vitro effects of exogenous carbon monoxide on oxidative stress and lipid metabolism in macrophages. Toxicol Ind Health 2014; pii: 0748233714558084. [Epub ahead of print]
9. Song G, Zong C, Zhang Z, et al. Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. Free Radic Biol Med 2015; 87: 58-68
10. Cao Y, Roursgaard M, Danielsen PH, et al. Carbon black nanoparticles promote endothelial activation and lipid accumulation in macrophages independently of intracellular ROS production. PLoS One 2014; 9: e106711
11. Petrick L, Rosenblat M, Paland N, Aviram M. Silicon dioxide nanoparticles increase macrophage atherogenicity: stimulation of cellular cytotoxicity, oxidative stress, and triglycerides accumulation. Environ Toxicol 2014. [Epub ahead of print]