Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton

BMC Neuroscience

Volumn 16, Issue 1, 2015, Pages

  Freischmidt, Axel ^a   Schöpflin, Marcel ^a   Feiler, Marisa S ^a   Fleck, Ann Katrin ^a   Ludolph, Albert C ^a   Weishaupt, Jochen H ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Actin; ALS; Amyotrophic lateral sclerosis; Cytoskeleton; Neurodegeneration; PFN1; Profilin 1

Indexed keywords

ACTIN; F ACTIN; MUTANT PROTEIN; PROFILIN; PROFILIN 1; UNCLASSIFIED DRUG; PFN1 PROTEIN, HUMAN; PROTEIN BINDING;

ACTIN FILAMENT; ACTIN POLYMERIZATION; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL STRUCTURE; DISEASE ASSOCIATION; EXON; FLUORESCENCE MICROSCOPY; GENE MUTATION; HAPLOINSUFFICIENCY; HEK293 CELL LINE; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; INTRON; MOTONEURON; PATHOGENICITY; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN-FRAGMENT COMPLEMENTATION ASSAY; RNA SPLICING; ULTRACENTRIFUGATION; WESTERN BLOTTING; GENETICS; HUMAN; METABOLISM; MUTATION;

ACTIN CYTOSKELETON; ACTINS; AMYOTROPHIC LATERAL SCLEROSIS; HUMANS; MUTATION; PROFILINS; PROTEIN BINDING;

EID: 84960337810     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/s12868-015-0214-y     Document Type: Article

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