Targeting of the human F8 at the multicopy rDNA locus in Hemophilia a patient-derived iPSCs using TALENickases

Biochemical and Biophysical Research Communications

Volumn 472, Issue 1, 2016, Pages 144-149

  Pang, Jialun ^a   Wu, Yong ^a   Li, Zhuo ^a   Hu, Zhiqing ^a   Wang, Xiaolin ^a   Hu, Xuyun ^a   Wang, Xiaoyan ^a   Liu, Xionghao ^a   Zhou, Miaojin ^a   Liu, Bo ^a   Wang, Yanchi ^a   Feng, Mai ^a   Liang, Desheng ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Hemophilia A; iPSCs; Multicopy; Ribosomal DNA; TALENickases

Indexed keywords

BLOOD CLOTTING FACTOR 8; MESSENGER RNA; NUCLEASE; RIBOSOME DNA; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NICKASE; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE I; F8 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; GENE LOCUS; GENE TARGETING; HEMOPHILIA A; HUMAN; HUMAN CELL; KIDNEY TUBULE EPITHELIUM; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; ANIMAL; BLOOD; COCULTURE; CYTOLOGY; GENE EXPRESSION; GENE THERAPY; GENETICS; INDUCED PLURIPOTENT STEM CELL; MALE; METABOLISM; PROCEDURES; URINE;

ANIMALS; COCULTURE TECHNIQUES; DEOXYRIBONUCLEASE I; DNA, RIBOSOMAL; FACTOR VIII; GENE EXPRESSION; GENE TARGETING; GENETIC THERAPY; HEMOPHILIA A; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; RNA, MESSENGER; URINE;

EID: 84960308834     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.02.083     Document Type: Article

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