-
1
-
-
39449103059
-
Infectious Diseases Society of America. 2008. The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America
-
Spellberg B, Guidos R, Gilbert D, Bradley J, Boucher HW, Scheld WM, Bartlett JG, Edwards J, Jr, Infectious Diseases Society of America. 2008. The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis 46:155-164. http://dx.doi.org/10.1086/524891.
-
Clin Infect Dis
, vol.46
, pp. 155-164
-
-
Spellberg, B.1
Guidos, R.2
Gilbert, D.3
Bradley, J.4
Boucher, H.W.5
Scheld, W.M.6
Bartlett, J.G.7
Edwards, J.8
-
2
-
-
84881256695
-
Infections and the rise of antimicrobial resistance
-
Department of Health, London, United Kingdom
-
Davies SC. 2013. Infections and the rise of antimicrobial resistance. Annual report of the Chief Medical Officer, vol 2, 2011. Department of Health, London, United Kingdom.
-
(2011)
Annual Report of the Chief Medical Officer
, vol.2
-
-
Davies, S.C.1
-
3
-
-
57749107808
-
Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
-
Boucher HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB, Scheld M, Spellberg B, Bartlett J. 2009. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 48:1-12. http://dx.doi.org/10.1086/595011.
-
(2009)
Clin Infect Dis
, vol.48
, pp. 1-12
-
-
Boucher, H.W.1
Talbot, G.H.2
Bradley, J.S.3
Edwards, J.E.4
Gilbert, D.5
Rice, L.B.6
Scheld, M.7
Spellberg, B.8
Bartlett, J.9
-
5
-
-
85026942052
-
-
Innovative Medicines Initiative, Brussels, Belgium
-
Innovative Medicines Initiative. 2010. COMBACTE (Combating Bacterial Resistance in Europe). Innovative Medicines Initiative, Brussels, Belgium. http://www.imi.europa.eu/content/combacte.
-
(2010)
COMBACTE (Combating Bacterial Resistance in Europe)
-
-
-
7
-
-
33846572283
-
The relationship between quinolone exposures and resistance amplification is characterized by an inverted-U: A new paradigm for optimizing pharmacodynamics to counter-select resistance
-
Tam VH, Louie A, Deziel MR, Liu W, Drusano GL. 2007. The relationship between quinolone exposures and resistance amplification is characterized by an inverted-U: a new paradigm for optimizing pharmacodynamics to counter-select resistance. Antimicrob Agents Chemother 51:744-747. http://dx.doi.org/10.1128/AAC.00334-06.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 744-747
-
-
Tam, V.H.1
Louie, A.2
Deziel, M.R.3
Liu, W.4
Drusano, G.L.5
-
8
-
-
0037417014
-
Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model
-
MacGowan AP, Rogers CA, Holt HA, Bowker KE. 2003. Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model. Antimicrob Agents Chemother 47:1088-1095. http://dx.doi.org/10.1128/AAC.47.3.1088-1095.2003.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1088-1095
-
-
MacGowan, A.P.1
Rogers, C.A.2
Holt, H.A.3
Bowker, K.E.4
-
9
-
-
0033836223
-
Selection of antibiotic-resistant bacterial mutants: Allelic diversity among fluoroquinolone-resistant mutants
-
Zhou J, Dong Y, Zhao X, Lee S, Amin A, Ramaswamy S, Domagala J, Musser JM, Drlica K. 2000. Selection of antibiotic-resistant bacterial mutants: allelic diversity among fluoroquinolone-resistant mutants. J Infect Dis 182:517-525. http://dx.doi.org/10.1086/315708.
-
(2000)
J Infect Dis
, vol.182
, pp. 517-525
-
-
Zhou, J.1
Dong, Y.2
Zhao, X.3
Lee, S.4
Amin, A.5
Ramaswamy, S.6
Domagala, J.7
Musser, J.M.8
Drlica, K.9
-
10
-
-
0034425797
-
Mutation prevention concentration as a measure of fluoroquinolone potency against mycobacteria
-
Sindelar G, Zhao X, Liew A, Dong Y, Lu T, Zhou J, Domagala J, Drlica K. 2000. Mutation prevention concentration as a measure of fluoroquinolone potency against mycobacteria. Antimicrob Agents Chemother 44:3337-3343. http://dx.doi.org/10.1128/AAC.44.12.3337-3343.2000.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 3337-3343
-
-
Sindelar, G.1
Zhao, X.2
Liew, A.3
Dong, Y.4
Lu, T.5
Zhou, J.6
Domagala, J.7
Drlica, K.8
-
11
-
-
0042743965
-
Application of a mathematical model to prevent in-vivo amplification of antibiotic-resistant bacterial populations during therapy
-
Jumbe N, Louie A, Leary R, Liu W, Deziel MR, Tam VH, Bachhawat R, Freeman C, Kahn JB, Bush K, Dudley MN, Miller MH, Drusano GL. 2003. Application of a mathematical model to prevent in-vivo amplification of antibiotic-resistant bacterial populations during therapy. J Clin Invest 112:275-285. http://dx.doi.org/10.1172/JCI200316814.
-
(2003)
J Clin Invest
, vol.112
, pp. 275-285
-
-
Jumbe, N.1
Louie, A.2
Leary, R.3
Liu, W.4
Deziel, M.R.5
Tam, V.H.6
Bachhawat, R.7
Freeman, C.8
Kahn, J.B.9
Bush, K.10
Dudley, M.N.11
Miller, M.H.12
Drusano, G.L.13
-
12
-
-
22544468795
-
Bacterial population responses to drug selective pressure: Examination of garenoxacin against Pseudomonas aeruginosa
-
Tam VH, Louie A, Deziel MR, Liu W, Leary R, Drusano GL. 2005. Bacterial population responses to drug selective pressure: examination of garenoxacin against Pseudomonas aeruginosa. J Infect Dis 192:420-428. http://dx.doi.org/10.1086/430611.
-
(2005)
J Infect Dis
, vol.192
, pp. 420-428
-
-
Tam, V.H.1
Louie, A.2
Deziel, M.R.3
Liu, W.4
Leary, R.5
Drusano, G.L.6
-
13
-
-
0036093097
-
Pharmacodynamics of the new fluoroquinolone gatifloxacin in murine thigh and lung infection models
-
Andes D, Craig WA. 2002. Pharmacodynamics of the new fluoroquinolone gatifloxacin in murine thigh and lung infection models. Antimicrob Agents Chemother 46:1665-1670. http://dx.doi.org/10.1128/AAC.46.6.1665-1670.2002.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1665-1670
-
-
Andes, D.1
Craig, W.A.2
-
14
-
-
67749147359
-
Pharmacodynamics of levofloxacin in a murine pneumonia model of Pseudomonas aeruginosa infection: Determination of epithelial lining fluid (ELF) targets
-
Louie A, Fregeau C, Liu W, Kulawy R, Drusano GL. 2009. Pharmacodynamics of levofloxacin in a murine pneumonia model of Pseudomonas aeruginosa infection: determination of epithelial lining fluid (ELF) targets. Antimicrob Agents Chemother 53:3325-3330. http://dx.doi.org/10.1128/AAC.00006-09.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3325-3330
-
-
Louie, A.1
Fregeau, C.2
Liu, W.3
Kulawy, R.4
Drusano, G.L.5
-
15
-
-
71249146344
-
Bacterial strain-to-strain variation in pharmacodynamic index magnitude, a hitherto unconsidered factor in establishing antibiotic clinical breakpoints
-
MacGowan AP, Reynolds R, Noel AR, Bowker KE. 2009. Bacterial strain-to-strain variation in pharmacodynamic index magnitude, a hitherto unconsidered factor in establishing antibiotic clinical breakpoints. Antimicrob Agents Chemother 53:5181-5184. http://dx.doi.org/10.1128/AAC.00118-09.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 5181-5184
-
-
MacGowan, A.P.1
Reynolds, R.2
Noel, A.R.3
Bowker, K.E.4
-
16
-
-
0037083238
-
Restricting the selection of antibiotic-resistant mutant bacteria: Measurement and potential use of the mutant selection window
-
Zhao X, Drlica K. 2002. Restricting the selection of antibiotic-resistant mutant bacteria: measurement and potential use of the mutant selection window. J Infect Dis 185:561-565. http://dx.doi.org/10.1086/338571.
-
(2002)
J Infect Dis
, vol.185
, pp. 561-565
-
-
Zhao, X.1
Drlica, K.2
-
17
-
-
0038414586
-
In vitro pharmacodynamics evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus
-
Firsov AA, Vostrov SN, Lubenko IY, Drlica K, Portnoy YA, Zinner SH. 2003. In vitro pharmacodynamics evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus. Antimicrob Agents Chemother 47:1604-1613. http://dx.doi.org/10.1128/AAC.47.5.1604-1613.2003.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1604-1613
-
-
Firsov, A.A.1
Vostrov, S.N.2
Lubenko, I.Y.3
Drlica, K.4
Portnoy, Y.A.5
Zinner, S.H.6
-
18
-
-
34249870835
-
Impact of drug-exposure intensity and duration of therapy on the emergence of Staphylococcus aureus resistance to a quinolone antimicrobial
-
Tam VH, Louie A, Fritsche TR, Deziel M, Liu W, Brown DL, Deshpande L, Leary R, Jones RN, Drusano GL. 2007. Impact of drug-exposure intensity and duration of therapy on the emergence of Staphylococcus aureus resistance to a quinolone antimicrobial. J Infect Dis 195:1818-1827. http://dx.doi.org/10.1086/518003.
-
(2007)
J Infect Dis
, vol.195
, pp. 1818-1827
-
-
Tam, V.H.1
Louie, A.2
Fritsche, T.R.3
Deziel, M.4
Liu, W.5
Brown, D.L.6
Deshpande, L.7
Leary, R.8
Jones, R.N.9
Drusano, G.L.10
-
19
-
-
58849137183
-
Impact of short-course quinolone therapy on susceptible and resistant populations of Staphylococcus aureus
-
Drusano GL, Liu W, Brown DL, Rice LB, Louie A. 2009. Impact of short-course quinolone therapy on susceptible and resistant populations of Staphylococcus aureus. J Infect Dis 199:219-226. http://dx.doi.org/10.1086/595739.
-
(2009)
J Infect Dis
, vol.199
, pp. 219-226
-
-
Drusano, G.L.1
Liu, W.2
Brown, D.L.3
Rice, L.B.4
Louie, A.5
-
20
-
-
29944438551
-
Quinolone efflux pumps play a central role in emergence of resistance to fluoroquinolones in Streptococcus pneumoniae
-
Jumbe NL, Louie A, Miller MH, Liu W, Deziel MR, Tam VH, Bachhawat R, Drusano GL. 2006. Quinolone efflux pumps play a central role in emergence of resistance to fluoroquinolones in Streptococcus pneumoniae. Antimicrob Agents Chemother 50:310-317. http://dx.doi.org/10.1128/AAC.50.1.310-317.2006.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 310-317
-
-
Jumbe, N.L.1
Louie, A.2
Miller, M.H.3
Liu, W.4
Deziel, M.R.5
Tam, V.H.6
Bachhawat, R.7
Drusano, G.L.8
-
21
-
-
35848938329
-
In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae
-
Louie A, Brown DL, Liu W, Kulawy RW, Deziel MR, Drusano GL. 2007. In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae. Antimicrob Agents Chemother 51:3988-4000. http://dx.doi.org/10.1128/AAC.00391-07.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3988-4000
-
-
Louie, A.1
Brown, D.L.2
Liu, W.3
Kulawy, R.W.4
Deziel, M.R.5
Drusano, G.L.6
-
22
-
-
84877116185
-
Comparative antibacterial effects of moxifloxacin and levofloxacin on Streptococcus pneumoniae strains with defined mechanisms of resistance: Impact of bacterial inoculum
-
Bowker KE, Garvey MI, Noel AR, Tomaselli SG, MacGowan AP. 2013. Comparative antibacterial effects of moxifloxacin and levofloxacin on Streptococcus pneumoniae strains with defined mechanisms of resistance: impact of bacterial inoculum. J Antimicrob Chemother 68:1130-1138. http://dx.doi.org/10.1093/jac/dks537.
-
(2013)
J Antimicrob Chemother
, vol.68
, pp. 1130-1138
-
-
Bowker, K.E.1
Garvey, M.I.2
Noel, A.R.3
Tomaselli, S.G.4
MacGowan, A.P.5
-
23
-
-
6944234949
-
Selection of a moxifloxacin dose that suppresses Mycobacterium tuberculosis resistance using an in vitro pharmacodynamic infection model and mathematical modeling
-
Gumbo T, Louie A, Deziel MR, Parsons LM, Salfinger M, Drusano GL. 2004. Selection of a moxifloxacin dose that suppresses Mycobacterium tuberculosis resistance using an in vitro pharmacodynamic infection model and mathematical modeling. J Infect Dis 190:1642-1651. http://dx.doi.org/10.1086/424849.
-
(2004)
J Infect Dis
, vol.190
, pp. 1642-1651
-
-
Gumbo, T.1
Louie, A.2
Deziel, M.R.3
Parsons, L.M.4
Salfinger, M.5
Drusano, G.L.6
-
24
-
-
34547631104
-
Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy
-
Louie A, Deziel MR, Liu W, Drusano GL. 2007. Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. Antimicrob Agents Chemother 51:2661-2667. http://dx.doi.org/10.1128/AAC.00073-07.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2661-2667
-
-
Louie, A.1
Deziel, M.R.2
Liu, W.3
Drusano, G.L.4
-
25
-
-
78751700304
-
Use of an in vitro pharmacodynamic model to derive a moxifloxacin regimen that optimizes kill of Yersinia pestis and prevents emergence of resistance
-
Louie A, Heine HS, Heine HS, VanScoy B, Eichas A, Files K, Fikes S, Brown DL, Liu W, Kinzig-Schippers M, Sörgel F, Drusano GL. 2011. Use of an in vitro pharmacodynamic model to derive a moxifloxacin regimen that optimizes kill of Yersinia pestis and prevents emergence of resistance. Antimicrob Agents Chemother 55:822-830. http://dx.doi.org/10.1128/AAC.00818-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 822-830
-
-
Louie, A.1
Heine, H.S.2
Heine, H.S.3
VanScoy, B.4
Eichas, A.5
Files, K.6
Fikes, S.7
Brown, D.L.8
Liu, W.9
Kinzig-Schippers, M.10
Sörgel, F.11
Drusano, G.L.12
-
26
-
-
79956321027
-
Comparative efficacies of candidate antibiotics against Yersinia pestis in an in vitro pharmacodynamic model
-
Louie A, Vanscoy B, Liu W, Kulawy R, Brown D, Heine HS, Drusano GL. 2011. Comparative efficacies of candidate antibiotics against Yersinia pestis in an in vitro pharmacodynamic model. Antimicrob Agents Chemother 55:2623-2628. http://dx.doi.org/10.1128/AAC.01374-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2623-2628
-
-
Louie, A.1
Vanscoy, B.2
Liu, W.3
Kulawy, R.4
Brown, D.5
Heine, H.S.6
Drusano, G.L.7
-
27
-
-
28844470668
-
Identification of effective antimicrobial regimens for use in humans for the therapy of Bacillus anthracis infections and post-exposure prophylaxis
-
Deziel M, Heine H, Louie A, Kao M, Byrne WR, Bassett J, Miller L, Bush K, Kelley M, Drusano GL. 2005. Identification of effective antimicrobial regimens for use in humans for the therapy of Bacillus anthracis infections and post-exposure prophylaxis. Antimicrob Agents Chemother 49:5099-5106. http://dx.doi.org/10.1128/AAC.49.12.5099-5106.2005.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 5099-5106
-
-
Deziel, M.1
Heine, H.2
Louie, A.3
Kao, M.4
Byrne, W.R.5
Bassett, J.6
Miller, L.7
Bush, K.8
Kelley, M.9
Drusano, G.L.10
-
28
-
-
46249110625
-
Use of an in vitro model of Bacillus anthracis infection to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance
-
Louie A, Heine HS, Kim K, Brown DL, VanScoy B, Liu W, Kinzig-Schippers M, F Sörgel Drusano GL. 2008. Use of an in vitro model of Bacillus anthracis infection to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance. Antimicrob Agents Chemother 52:2486-2496. http://dx.doi.org/10.1128/AAC.01439-07.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2486-2496
-
-
Louie, A.1
Heine, H.S.2
Kim, K.3
Brown, D.L.4
VanScoy, B.5
Liu, W.6
Kinzig-Schippers, M.7
Sörgel, F.8
Drusano, G.L.9
-
29
-
-
70350318143
-
Impact of spore biology on the rate of kill and suppression of resistance in Bacillus anthracis
-
Drusano GL, Okusanya OO, Okusanya AO, van Scoy B, Brown DL, Fregeau C, Kulawy R, Kinzig M, Sörgel F, Heine HS, Louie A. 2009. Impact of spore biology on the rate of kill and suppression of resistance in Bacillus anthracis. Antimicrob Agents Chemother 53:4718-4725. http://dx.doi.org/10.1128/AAC.00802-09.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4718-4725
-
-
Drusano, G.L.1
Okusanya, O.O.2
Okusanya, A.O.3
Van Scoy, B.4
Brown, D.L.5
Fregeau, C.6
Kulawy, R.7
Kinzig, M.8
Sörgel, F.9
Heine, H.S.10
Louie, A.11
-
30
-
-
77952650628
-
Impact of different carbapenems and regimens of administration on resistance emergence for three isogenic Pseudomonas aeruginosa strains with differing mechanisms of resistance
-
Louie A, Bied A, Fregeau C, Van Scoy B, Brown D, Liu W, Bush K, Queenan AM, Morrow B, Khashab M, Kahn JB, Nicholson S, Kulawy R, Drusano GL. 2010. Impact of different carbapenems and regimens of administration on resistance emergence for three isogenic Pseudomonas aeruginosa strains with differing mechanisms of resistance. Antimicrob Agents Chemother 54:2638-2645. http://dx.doi.org/10.1128/AAC.01721-09.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2638-2645
-
-
Louie, A.1
Bied, A.2
Fregeau, C.3
Van Scoy, B.4
Brown, D.5
Liu, W.6
Bush, K.7
Queenan, A.M.8
Morrow, B.9
Khashab, M.10
Kahn, J.B.11
Nicholson, S.12
Kulawy, R.13
Drusano, G.L.14
-
31
-
-
79959215008
-
Meropenem penetration into epithelial lining fluid in mice and men and delineation of exposure targets
-
Drusano GL, Lodise TP, Melnick D, Liu W, Oliver A, Mena A, VanScoy B, Louie A. 2011. Meropenem penetration into epithelial lining fluid in mice and men and delineation of exposure targets. Antimicrob Agents Chemother 55:3406-3412. http://dx.doi.org/10.1128/AAC.01559-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 3406-3412
-
-
Drusano, G.L.1
Lodise, T.P.2
Melnick, D.3
Liu, W.4
Oliver, A.5
Mena, A.6
VanScoy, B.7
Louie, A.8
-
32
-
-
84887460013
-
Impact of bolus dosing versus continuous infusion of piperacillin and tazobactam on the development of antimicrobial resistance in Pseudomonas aeruginosa
-
Felton T, Goodwin J, O'Connor L, Sharp A, Gregson L, Livermore J, Howard SJ, Neely MN, Hope WW. 2013. Impact of bolus dosing versus continuous infusion of piperacillin and tazobactam on the development of antimicrobial resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 57:5811-5819. http://dx.doi.org/10.1128/AAC.00867-13.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 5811-5819
-
-
Felton, T.1
Goodwin, J.2
O'Connor, L.3
Sharp, A.4
Gregson, L.5
Livermore, J.6
Howard, S.J.7
Neely, M.N.8
Hope, W.W.9
-
33
-
-
84866338419
-
Pharmacodynamics of the antibacterial effect and emergence of resistance to doripenem in Pseudomonas aeruginosa and Acinetobacter baumannii in an in vitro pharmacodynamic model
-
Bowker KE, Noel AR, Tomaselli SG, Elliott H, MacGowan AP. 2012. Pharmacodynamics of the antibacterial effect and emergence of resistance to doripenem in Pseudomonas aeruginosa and Acinetobacter baumannii in an in vitro pharmacodynamic model. Antimicrob Agents Chemother 56:5009-5015. http://dx.doi.org/10.1128/AAC.06111-11.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 5009-5015
-
-
Bowker, K.E.1
Noel, A.R.2
Tomaselli, S.G.3
Elliott, H.4
MacGowan, A.P.5
-
34
-
-
84877849969
-
Pharmacodynamics of ceftaroline against Staphylococcus aureus studied in an in vitro pharmacokinetic model of infection
-
MacGowan AP, Noel AR, Tomaselli S, Bowker KE. 2013. Pharmacodynamics of ceftaroline against Staphylococcus aureus studied in an in vitro pharmacokinetic model of infection. Antimicrob Agents Chemother 57:2451-2456. http://dx.doi.org/10.1128/AAC.01386-12.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 2451-2456
-
-
MacGowan, A.P.1
Noel, A.R.2
Tomaselli, S.3
Bowker, K.E.4
-
35
-
-
42049113177
-
Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection
-
MacGowan AP, Bowker KE, Noel AR. 2008. Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection. Antimicrob Agents Chemother 52:1401-1406. http://dx.doi.org/10.1128/AAC.01153-07.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1401-1406
-
-
MacGowan, A.P.1
Bowker, K.E.2
Noel, A.R.3
-
36
-
-
79953193774
-
Pharmacodynamics of razupenem studied in an in vitro pharmacokinetic model of infection
-
MacGowan AP, Noel AR, Tomaselli S, Elliott HC, Bowker KE. 2011. Pharmacodynamics of razupenem studied in an in vitro pharmacokinetic model of infection. Antimicrob Agents Chemother 55:1436-1442. http://dx.doi.org/10.1128/AAC.00936-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 1436-1442
-
-
MacGowan, A.P.1
Noel, A.R.2
Tomaselli, S.3
Elliott, H.C.4
Bowker, K.E.5
-
37
-
-
33846142868
-
Isoniazid's bactericidal activity ceases because of the emergence of resistance, not depletion of Mycobacterium tuberculosis in the log phase of growth
-
Gumbo T, Louie A, Liu W, Ambrose PG, Bhavnani SM, Brown D, Drusano GL. 2007. Isoniazid's bactericidal activity ceases because of the emergence of resistance, not depletion of Mycobacterium tuberculosis in the log phase of growth. J Infect Dis 195:194-201. http://dx.doi.org/10.1086/510247.
-
(2007)
J Infect Dis
, vol.195
, pp. 194-201
-
-
Gumbo, T.1
Louie, A.2
Liu, W.3
Ambrose, P.G.4
Bhavnani, S.M.5
Brown, D.6
Drusano, G.L.7
-
38
-
-
34447251840
-
Isoniazid bactericidal activity and resistance emergence: Integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations
-
Gumbo T, Louie A, Brown D, Ambrose PG, Bhavnani SM, Drusano GL. 2007. Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations. Antimicrob Agents Chemother 51:2329-2336. http://dx.doi.org/10.1128/AAC.00185-07.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2329-2336
-
-
Gumbo, T.1
Louie, A.2
Brown, D.3
Ambrose, P.G.4
Bhavnani, S.M.5
Drusano, G.L.6
-
39
-
-
35848959226
-
Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin
-
Gumbo T, Louie A, Deziel MR, Liu W, Parsons LM, Salfinger M, Drusano GL. 2007. Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin. Antimicrob Agents Chemother 51:3781-3788. http://dx.doi.org/10.1128/AAC.01533-06.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3781-3788
-
-
Gumbo, T.1
Louie, A.2
Deziel, M.R.3
Liu, W.4
Parsons, L.M.5
Salfinger, M.6
Drusano, G.L.7
-
40
-
-
78751681331
-
Pharmacodynamics of telavancin studied in an in vitro pharmacokinetic model of infection
-
MacGowan AP, Noel AR, Tomaselli S, Elliott HC, Bowker KE. 2011. Pharmacodynamics of telavancin studied in an in vitro pharmacokinetic model of infection. Antimicrob Agents Chemother 55:867-873. http://dx.doi.org/10.1128/AAC.00933-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 867-873
-
-
MacGowan, A.P.1
Noel, A.R.2
Tomaselli, S.3
Elliott, H.C.4
Bowker, K.E.5
-
41
-
-
73949110796
-
Comparative antibacterial effects of daptomycin, vancomycin and teicoplanin studied in an in vitro pharmacokinetic model of infection
-
Bowker KE, Noel AR, MacGowan AP. 2009. Comparative antibacterial effects of daptomycin, vancomycin and teicoplanin studied in an in vitro pharmacokinetic model of infection. J Antimicrob Chemother 64:1044-1051. http://dx.doi.org/10.1093/jac/dkp289.
-
(2009)
J Antimicrob Chemother
, vol.64
, pp. 1044-1051
-
-
Bowker, K.E.1
Noel, A.R.2
MacGowan, A.P.3
-
42
-
-
0037229075
-
Mutant prevention concentration of gemifloxacin for clinical isolates of Streptococcus pneumoniae
-
Hansen GT, Metzler K, Drlica K, Blondeau JM. 2003. Mutant prevention concentration of gemifloxacin for clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 47:440-441. http://dx.doi.org/10.1128/AAC.47.1.440-441.2003.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 440-441
-
-
Hansen, G.T.1
Metzler, K.2
Drlica, K.3
Blondeau, J.M.4
-
43
-
-
0038121041
-
Fluoroquinolones: Action and resistance
-
Drlica K, Malik M. 2003. Fluoroquinolones: action and resistance. Curr Top Med Chem 3:249-282. http://dx.doi.org/10.2174/1568026033452537.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 249-282
-
-
Drlica, K.1
Malik, M.2
-
44
-
-
0035139520
-
Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae
-
Blondeau JM, Zhao X, G Hansen X, Drlica K. 2001. Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 45:433-438. http://dx.doi.org/10.1128/AAC.45.2.433-438.2001.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 433-438
-
-
Blondeau, J.M.1
Zhao, X.2
G Hansen, X.3
Drlica, K.4
-
45
-
-
44449122254
-
Enrichment of fluoroquinolone-resistant Staphylococcus aureus: Oscillating ciprofloxacin concentrations simulated at the upper and lower portions of the mutant selection window
-
Firsov AA, Lubenko IY, Smirnova MV, Strukova EN, Zinner SH. 2008. Enrichment of fluoroquinolone-resistant Staphylococcus aureus: oscillating ciprofloxacin concentrations simulated at the upper and lower portions of the mutant selection window. Antimicrob Agents Chemother 52:1924-1928. http://dx.doi.org/10.1128/AAC.01371-07.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1924-1928
-
-
Firsov, A.A.1
Lubenko, I.Y.2
Smirnova, M.V.3
Strukova, E.N.4
Zinner, S.H.5
-
46
-
-
2142662135
-
Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy
-
Croisier D, Etienne M, Bergoin E, Charles PE, Lequeu C, Piroth L, Portier H, Chavanet P. 2004. Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy. Antimicrob Agents Chemother 48:1699-1707. http://dx.doi.org/10.1128/AAC.48.5.1699-1707.2004.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1699-1707
-
-
Croisier, D.1
Etienne, M.2
Bergoin, E.3
Charles, P.E.4
Lequeu, C.5
Piroth, L.6
Portier, H.7
Chavanet, P.8
-
47
-
-
77957338404
-
Impact of burden on granulocyte clearance of bacteria in a mouse thigh infection model
-
Drusano GL, Fregeau C, Liu W, Brown DL, Louie A. 2010. Impact of burden on granulocyte clearance of bacteria in a mouse thigh infection model. Antimicrob Agents Chemother 54:4368-4372. http://dx.doi.org/10.1128/AAC.00133-10.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 4368-4372
-
-
Drusano, G.L.1
Fregeau, C.2
Liu, W.3
Brown, D.L.4
Louie, A.5
-
48
-
-
79956331997
-
Saturability of granulocyte kill of Pseudomonas aeruginosa in a murine model of pneumonia
-
Drusano GL, Vanscoy B, Liu W, Fikes S, Brown D, Louie A. 2011. Saturability of granulocyte kill of Pseudomonas aeruginosa in a murine model of pneumonia. Antimicrob Agents Chemother 55:2693-2695. http://dx.doi.org/10.1128/AAC.01687-10.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2693-2695
-
-
Drusano, G.L.1
Vanscoy, B.2
Liu, W.3
Fikes, S.4
Brown, D.5
Louie, A.6
-
49
-
-
84909992516
-
Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model
-
Drusano GL, Liu W, Fikes S, Cirz R, Robbins N, Kurhanewicz S, Rodriquez J, Brown D, Baluya D, Louie A. 2014. Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model. J Infect Dis 210:1319-1324. http://dx.doi.org/10.1093/infdis/jiu237.
-
(2014)
J Infect Dis
, vol.210
, pp. 1319-1324
-
-
Drusano, G.L.1
Liu, W.2
Fikes, S.3
Cirz, R.4
Robbins, N.5
Kurhanewicz, S.6
Rodriquez, J.7
Brown, D.8
Baluya, D.9
Louie, A.10
-
50
-
-
0345283255
-
Comparison of 8 vs 15 days of therapy for patients with ventilator-associated pneumonia in adults: A randomized trial
-
Chastre J, Wolff M, Fagon JY, Chevret S, Thomas F, Wermert D, Clementi E, Gonzalez J, Jusserand D, Asfar P, Perrin D, Fieux F, Aubas S, PneumA Trial Group. 2003. Comparison of 8 vs 15 days of therapy for patients with ventilator-associated pneumonia in adults: a randomized trial. JAMA 290:2588-2598. http://dx.doi.org/10.1001/jama.290.19.2588.
-
(2003)
JAMA
, vol.290
, pp. 2588-2598
-
-
Chastre, J.1
Wolff, M.2
Fagon, J.Y.3
Chevret, S.4
Thomas, F.5
Wermert, D.6
Clementi, E.7
Gonzalez, J.8
Jusserand, D.9
Asfar, P.10
Perrin, D.11
Fieux, F.12
Aubas, S.13
-
51
-
-
2142760947
-
Antimicrobial pharmacodynamics: The interactions between bug and drug
-
Drusano GL. 2004. Antimicrobial pharmacodynamics: the interactions between bug and drug. Nat Rev Microbiol 2:289-300. http://dx.doi.org/10.1038/nrmicro862.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 289-300
-
-
Drusano, G.L.1
-
52
-
-
0017226783
-
Purification and properties of DNA-dependent RNA polymerase from Mycobacterium tuberculosis H37RV
-
Harshey RM, Ramakirishnan T. 1976. Purification and properties of DNA-dependent RNA polymerase from Mycobacterium tuberculosis H37RV. Biochim Biophys Acta 432:49-59. http://dx.doi.org/10.1016/0005-2787(76)90040-X.
-
(1976)
Biochim Biophys Acta
, vol.432
, pp. 49-59
-
-
Harshey, R.M.1
Ramakirishnan, T.2
|