Chromatin modulation of herpesvirus lytic gene expression: Managing nucleosome density and heterochromatic histone modifications

mBio

Volumn 7, Issue 1, 2016, Pages

  Kristie, Thomas M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DENSITY; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN MODULATION; DNA REPLICATION; GENE EXPRESSION; GENETIC ASSOCIATION; HERPESVIRIDAE; HISTONE METHYLATION; HISTONE MODIFICATION; NONHUMAN; NOTE; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; VIRUS E GENE; VIRUS GENE; VIRUS GENOME; VIRUS LATENCY; VIRUS REPLICATION; GENE EXPRESSION REGULATION; GENETICS; HERPES SIMPLEX VIRUS 1; HISTONE CODE; HOST PATHOGEN INTERACTION; HUMAN; PHYSIOLOGY; VIROLOGY;

CHROMATIN; IMMEDIATE EARLY PROTEIN; NUCLEOSOME;

CHROMATIN; GENE EXPRESSION; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; HISTONE CODE; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMEDIATE-EARLY PROTEINS; NUCLEOSOMES; VIRUS LATENCY; VIRUS REPLICATION;

EID: 84960153750     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00098-16     Document Type: Note

References (19)

1. Lacasse JJ, Schang LM. 2012. Herpes simplex virus 1 DNA is in unstable nucleosomes throughout the lytic infection cycle, and the instability of the nucleosomes is independent of DNA replication. J Virol 86:11287–11300. http://dx.doi.org/10.1128/JVI.01468-12.
2. Knipe DM, Cliffe A. 2008. Chromatin control of herpes simplex virus lytic and latent infection. Nat Rev Microbiol 6:211–221. http://dx.doi.org/10.1038/nrmicro1794.
3. Liang Y, Vogel JL, Narayanan A, Peng H, Kristie TM. 2009. Inhibition of the histone demethylase LSD1 blocks alpha-herpesvirus lytic replication and reactivation from latency. Nat Med 15:1312–1317. http://dx.doi.org/10.1038/nm.2051.
4. Silva L, Cliffe A, Chang L, Knipe DM. 2008. Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation. PLoS Pathog 4:e1000071. http://dx.doi.org/10.1371/journal.ppat.1000071.
5. Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, Ott M, Margolis D, Nieto A, Nevels M, Parks RJ, Kristie TM. 2013. Snapshots: chromatin control of viral infection. Virology 435:141–156. http://dx.doi.org/10.1016/j.virol.2012.09.023.
6. Vogel JL, Kristie TM. 2013. The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection. Viruses 5:1272–1291. http://dx.doi.org/10.3390/v5051272.
7. Lee JS, Raja P, Knipe DM. 2016. Herpesviral ICP0 protein promotes two waves of heterochromatin removal on an early viral promoter during lytic infection. mBio 7:e02007-15. http://dx.doi.org/10.1128/mBio.02007-15.
8. Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P. 2014. EZH2 inhibitor efficacy in non-Hodgkin’s lymphoma does not require suppression of H3K27 monomethylation. Chem Biol 21:1463–1475. http://dx.doi.org/10.1016/j.chembiol.2014.09.017.
9. Knutson SK, Wigle TJ, Warholic NM, Sneeringer CJ, Allain CJ, Klaus CR, Sacks JD, Raimondi A, Majer CR, Song J, Scott MP, Jin L, Smith JJ, Olhava EJ, Chesworth R, Moyer MP, Richon VM, Copeland RA, Keilhack H, Pollock RM, Kuntz KW. 2012. A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. Nat Chem Biol 8:890–896. http://dx.doi.org/10.1038/nchembio.1084.
10. Oh HS, Bryant KF, Nieland TJ, Mazumder A, Bagul M, Bathe M, Root DE, Knipe DM. 2014. A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression. mBio 5:e01086-01013. http://dx.doi.org/10.1128/mBio.01086-13.
11. Boutell C, Everett RD. 2013. Regulation of alphaherpesvirus infections by the ICP0 family of proteins. J Gen Virol 94:465–481. http://dx.doi.org/10.1099/vir.0.048900-0.
12. Diner BA, Lum KK, Javitt A, Cristea IM. 2015. Interactions of the antiviral factor interferon gamma-inducible protein 16 (IFI16) mediate immune signaling and herpes simplex virus-1 immunosuppression. Mol Cell Proteomics 14:2341–2356. http://dx.doi.org/10.1074/mcp.M114.047068.
13. Johnson KE, Bottero V, Flaherty S, Dutta S, Singh VV, Chandran B. 2014. IFI16 restricts HSV-1 replication by accumulating on the HSV-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications. PLoS Pathog 10:e1004503. http://dx.doi.org/10.1371/journal.ppat.1004503.
14. Lukashchuk V, Everett RD. 2010. Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx. J Virol 84:4026–4040. http://dx.doi.org/10.1128/JVI.02597-09.
15. Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM. 2013. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A 110:E4492–E4501. http://dx.doi.org/10.1073/pnas.1316194110.
16. Gu H, Liang Y, Mandel G, Roizman B. 2005. Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proc Natl Acad Sci U S A 102: 7571–7576. http://dx.doi.org/10.1073/pnas.0502658102.
17. Gu H, Roizman B. 2007. Herpes simplex virus-infected cell protein 0 blocks the silencing of viralDNAby dissociating histone deacetylases from the CoREST-REST complex. Proc Natl Acad SciUSA 104:-17134–17139. http://dx.doi.org/10.1073/pnas.0707266104.
18. Kalamvoki M, Roizman B. 2010. Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression. Proc Natl Acad Sci U S A 107:17721–17726. http://dx.doi.org/10.1073/pnas.1012991107.
19. Cliffe AR, Knipe DM. 2008. Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection. J Virol 82:12030–12038. http://dx.doi.org/10.1128/JVI.01575-08.