Efficacy, safety and prognostic benefit of intravenous iron therapy with ferric carboxymaltose in patients with heart failure and left ventricular dysfunction

International Journal of Cardiology

Volumn 202, Issue , 2016, Pages 118-120

  Robles Mezcua, Ainhoa ^a   González Cruces, Noemí ^a   Ruiz Salas, Amalio ^a   Morcillo Hidalgo, Luis ^a   Robledo Carmona, Juan ^a   Gómez Doblas, Juan José ^a   De Teresa, Eduardo ^a   García Pinilla, José Manuel ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

Author keywords

Anaemia; Cardiovascular safety; Ferric carboxymaltose; Functional outcome; Intravenous iron; Iron deficiency

Indexed keywords

FERRIC CARBOXYMALTOSE; FERRITIN; HEMOGLOBIN; IRON; TRANSFERRIN; FERRIC ION; MALTOSE;

ADULT; AEROBIC METABOLISM; AGED; ANEMIA; ATRIAL FIBRILLATION; CARDIAC RESYNCHRONIZATION THERAPY; COMORBIDITY; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DEFIBRILLATION; DIABETES MELLITUS; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; DYSLIPIDEMIA; ENERGY YIELD; FEMALE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CONTRACTILITY; HEMATOCRIT; HUMAN; HYPERTENSION; HYPERTROPHIC CARDIOMYOPATHY; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON THERAPY; ISCHEMIA; KIDNEY FUNCTION; LETTER; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; OXYGEN TRANSPORT; PERIPARTUM CARDIOMYOPATHY; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; QUALITY OF LIFE; RETROSPECTIVE STUDY; ANALOGS AND DERIVATIVES; ANEMIA, IRON-DEFICIENCY; BLOOD; FOLLOW UP; HEART LEFT VENTRICLE FUNCTION; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; TREATMENT OUTCOME;

AGED; ANEMIA, IRON-DEFICIENCY; FEMALE; FERRIC COMPOUNDS; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MALTOSE; MIDDLE AGED; PROGNOSIS; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84960153658     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.08.204     Document Type: Article

References (10)

1. A. Cohen-Solal, C. Leclercq, G. Deray, and et al. Iron deficiency: an emerging therapeutic target in heart failure Heart 100 2014 1414 1420
2. M. Schou, H. Bosselmann, F. Gaborit, and et al. Iron deficiency: prevalence and relation to cardiovascular biomarkers in heart failure outpatients Int. J. Cardiol. 195 2015 143 148
3. C. Enjuanes, I.T. Klip, J. Bruguera, and et al. Iron deficiency and health-related quality of life in chronic heart failure: results from a multicenter European study Int. J. Cardiol. 174 2014 268 275
4. H.P. Rocca, and H.J. Crijins Iron i.v. in heart failure: ready for implementation? Eur. Heart J. 36 2015 645 647
5. S.D. Anker, J. Comin-Colet, G. Filippatos, and et al. Ferric carboxymaltose in patients with heart failure and iron deficiency N. Engl. J. Med. 361 2009 2436 2448
6. T. McDonagh, and I. Macdougall Iron therapy for the treatment of iron deficiency in chronic heart failure: intravenous or oral? Eur. J. Heart Fail. 17 2015 248 262
7. J.E. Toblli, G. Cao, and M. Angerosa Cardiovascular outcomes of intravenous iron in perspective of clinical trials and the use of different iron preparations Int. J. Cardiol. 187 2015 196 197
8. P. Ponikowski, D.J. Van Veldhuisen, J. Comin-Colet, and et al. Rationale and design of the CONFIRM-HF Study: a double-blind, randomized, placebo-controlled study to assess the effects of intravenous ferric carboxymaltose on functional capacity in patients with chronic heart failure and iron deficiency ESC Heart Fail. 1 2014 52 58
9. P. Ponikowski, D.J. Van Veldhuisen, J. Comin-Colet, and et al. Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency Eur. Heart J. 36 2015 657 668
10. B.N. Reed, E.A. Blair, E.M. Thudium, and et al. Effects of an accelerated intravenous iron regimen in hospitalized patients with advanced heart failure and iron deficiency Pharmacotherapy 35 2015 64 71