-
1
-
-
84922927615
-
Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms
-
Martin-Loeches I, Torres A, Rinaudo M, et al. Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms. J Infect 2015;70:213-222.
-
(2015)
J Infect
, vol.70
, pp. 213-222
-
-
Martin-Loeches, I.1
Torres, A.2
Rinaudo, M.3
-
2
-
-
84906087349
-
Epidemiology and predictors of multidrug-resistant community-acquired and healthcare-associated pneumonia
-
Gross AE, Van Schooneveld TC, Olsen KM, et al. Epidemiology and predictors of multidrug-resistant community-acquired and healthcare-associated pneumonia. Antimicrob Agents Chemother 2014;58:5262-5268.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 5262-5268
-
-
Gross, A.E.1
Van Schooneveld, T.C.2
Olsen, K.M.3
-
3
-
-
84885863973
-
Multidrug-resistant pathogens in hospitalised patients coming from the community with pneumonia: A European perspective
-
Aliberti S, Cilloniz C, Chalmers JD, et al. Multidrug-resistant pathogens in hospitalised patients coming from the community with pneumonia: a European perspective. Thorax 2013;68:997-999.
-
(2013)
Thorax
, vol.68
, pp. 997-999
-
-
Aliberti, S.1
Cilloniz, C.2
Chalmers, J.D.3
-
4
-
-
34247847949
-
The impact of multidrug resistance on the outcomes of critically ill patients with Gram-negative bacterial pneumonia
-
Kwa AL, Low JG, Lee E, et al. The impact of multidrug resistance on the outcomes of critically ill patients with Gram-negative bacterial pneumonia. Diagn Microbiol Infect Dis 2007;58:99-104.
-
(2007)
Diagn Microbiol Infect Dis
, vol.58
, pp. 99-104
-
-
Kwa, A.L.1
Low, J.G.2
Lee, E.3
-
5
-
-
84911915945
-
Epidemiology of methicillin-resistant Staphylococcus aureus pneumonia in community hospitals
-
Lewis SS, Walker VJ, Lee MS, et al. Epidemiology of methicillin-resistant Staphylococcus aureus pneumonia in community hospitals. Infect Control Hosp Epidemiol 2014;35:1452-1457.
-
(2014)
Infect Control Hosp Epidemiol
, vol.35
, pp. 1452-1457
-
-
Lewis, S.S.1
Walker, V.J.2
Lee, M.S.3
-
6
-
-
84961170370
-
Application of a methicillin-resistant Staphylococcus aureus risk score for community-onset pneumonia patients and outcomes with initial treatment
-
Teshome BF, Lee GC, Reveles KR, et al. Application of a methicillin-resistant Staphylococcus aureus risk score for community-onset pneumonia patients and outcomes with initial treatment. BMC Infect Dis 2015;15:380.
-
(2015)
BMC Infect Dis
, vol.15
, pp. 380
-
-
Teshome, B.F.1
Lee, G.C.2
Reveles, K.R.3
-
7
-
-
68249109400
-
Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units
-
Koulenti D, Lisboa T, Brun-Buisson C, et al., EU-VAP/CAP Study Group. Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units. Crit Care Med 2009;37:2360-2368.
-
(2009)
Crit Care Med
, vol.37
, pp. 2360-2368
-
-
Koulenti, D.1
Lisboa, T.2
Brun-Buisson, C.3
-
10
-
-
84865956018
-
Does resistance in severe infections caused by methicillin-resistant Staphylococcus aureus give you the 'creeps'?
-
Brink AJ. Does resistance in severe infections caused by methicillin-resistant Staphylococcus aureus give you the 'creeps'? Curr Opin Crit Care 2012;18:451-459.
-
(2012)
Curr Opin Crit Care
, vol.18
, pp. 451-459
-
-
Brink, A.J.1
-
11
-
-
84903151483
-
Guidelines for therapeutic drug monitoring of vancomycin: A systematic review
-
Ye ZK, Li C, Zhai SD. Guidelines for therapeutic drug monitoring of vancomycin: a systematic review. PLoS One 2014;9:e99044.
-
(2014)
PLoS One
, vol.9
, pp. e99044
-
-
Ye, Z.K.1
Li, C.2
Zhai, S.D.3
-
12
-
-
84856937734
-
Linezolid in methicillinresistant Staphylococcus aureus nosocomial pneumonia: A randomized, controlled study
-
Wunderink RG, Niederman MS, Kollef MH, et al. Linezolid in methicillinresistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study. Clin Infect Dis 2012;54:621-629.
-
(2012)
Clin Infect Dis
, vol.54
, pp. 621-629
-
-
Wunderink, R.G.1
Niederman, M.S.2
Kollef, M.H.3
-
13
-
-
84875418116
-
Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patients
-
Tumbarello M, De Pascale G, Trecarichi EM, et al. Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patients. Intensive Care Med 2013;39:682-692.
-
(2013)
Intensive Care Med
, vol.39
, pp. 682-692
-
-
Tumbarello, M.1
De Pascale, G.2
Trecarichi, E.M.3
-
14
-
-
84939937583
-
Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria
-
Bassetti M, De Waele JJ, Eggimann P, et al. Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria. Intensive Care Med 2015;41:776-795.
-
(2015)
Intensive Care Med
, vol.41
, pp. 776-795
-
-
Bassetti, M.1
De Waele, J.J.2
Eggimann, P.3
-
15
-
-
79953848771
-
Ceftaroline: A novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus
-
Saravolatz LD, Stein GE, Johnson LB. Ceftaroline: a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2011;52:1156-1163.
-
(2011)
Clin Infect Dis
, vol.52
, pp. 1156-1163
-
-
Saravolatz, L.D.1
Stein, G.E.2
Johnson, L.B.3
-
16
-
-
84903374556
-
Activity of ceftaroline and comparator agents tested against contemporary Gram-positive and -negative (2011) isolates collected in Europe, Turkey, and Israel
-
Castanheira M, Jones RN, Sader HS. Activity of ceftaroline and comparator agents tested against contemporary Gram-positive and -negative (2011) isolates collected in Europe, Turkey, and Israel. J Chemother 2014;26:202-210.
-
(2014)
J Chemother
, vol.26
, pp. 202-210
-
-
Castanheira, M.1
Jones, R.N.2
Sader, H.S.3
-
17
-
-
84895864880
-
Ceftaroline activity against bacterial organisms isolated from acute bacterial skin and skin structure infections in United States medical centers (2009-2011)
-
Pfaller MA, Flamm RK, Sader HS, Jones RN. Ceftaroline activity against bacterial organisms isolated from acute bacterial skin and skin structure infections in United States medical centers (2009-2011). Diagn Microbiol Infect Dis 2014;78:422-428.
-
(2014)
Diagn Microbiol Infect Dis
, vol.78
, pp. 422-428
-
-
Pfaller, M.A.1
Flamm, R.K.2
Sader, H.S.3
Jones, R.N.4
-
18
-
-
79951940148
-
In vitro activity of ceftobiprole against frequently encountered aerobic and facultative Gram-positive and Gram-negative bacterial pathogens: Results of the CANWARD 2007-2009 study
-
Walkty A, Adam HJ, Laverdière M, et al., Canadian Antimicrobial Resistance Alliance (CARA). In vitro activity of ceftobiprole against frequently encountered aerobic and facultative Gram-positive and Gram-negative bacterial pathogens: results of the CANWARD 2007-2009 study. Diagn Microbiol Infect Dis 2011;69:348-355.
-
(2011)
Diagn Microbiol Infect Dis
, vol.69
, pp. 348-355
-
-
Canadian Antimicrobial Resistance Alliance (CARA)1
Walkty, A.2
Adam, H.J.3
Laverdière, M.4
-
19
-
-
79954622500
-
FOCUS 1: A randomized, double-blinded, multicentre, phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
-
File TM Jr, Low DE, Eckburg PB, et al., FOCUS 1 investigators. FOCUS 1: a randomized, double-blinded, multicentre, phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011;66(Suppl 3):iii19-iii32.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. iii19-iii32
-
-
File, T.M.1
Low, D.E.2
Eckburg, P.B.3
-
20
-
-
79954622500
-
FOCUS 2: A randomized, double-blinded, multicentre, phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
-
Low DE, File TM Jr, Eckburg PB, et al., FOCUS 2 investigators. FOCUS 2: a randomized, double-blinded, multicentre, phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011;66(Suppl 3):iii33-iii44.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. iii33-iii44
-
-
Low, D.E.1
File, T.M.2
Eckburg, P.B.3
-
21
-
-
79954568574
-
Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia
-
Rank DR, Friedland HD, Laudano JB. Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia. J Antimicrob Chemother 2011;66(Suppl 3):iii53-iii59.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. iii53-iii59
-
-
Rank, D.R.1
Friedland, H.D.2
Laudano, J.B.3
-
22
-
-
84921911468
-
Assessment of time to clinical response, a proxy for discharge readiness, among hospitalized patients with community-acquired pneumonia who received either ceftaroline fosamil or ceftriaxone in two phase III FOCUS trials
-
Lodise TP, Anzueto AR, Weber DJ, et al. Assessment of time to clinical response, a proxy for discharge readiness, among hospitalized patients with community-acquired pneumonia who received either ceftaroline fosamil or ceftriaxone in two phase III FOCUS trials. Antimicrob Agents Chemother 2015;59:1119-1126.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 1119-1126
-
-
Lodise, T.P.1
Anzueto, A.R.2
Weber, D.J.3
-
23
-
-
84925504979
-
Pharmacokinetic/pharmacodynamic analysis to evaluate ceftaroline fosamil dosing regimens for the treatment of community-acquired bacterial pneumonia and complicated skin and skinstructure infections in patients with normal and impaired renal function
-
Canut A, Isla A, Rodríguez-Gascón A. Pharmacokinetic/pharmacodynamic analysis to evaluate ceftaroline fosamil dosing regimens for the treatment of community-acquired bacterial pneumonia and complicated skin and skinstructure infections in patients with normal and impaired renal function. Int J Antimicrob Agents 2015;45:399-405. PK/PD analysis supporting the use of high-dose ceftaroline in patients with suspected or confirmed MRSA infections.
-
(2015)
Int J Antimicrob Agents
, vol.45
, pp. 399-405
-
-
Canut, A.1
Isla, A.2
Rodríguez-Gascón, A.3
-
24
-
-
84857065297
-
A randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation
-
Nicholson SC, Welte T, File TM Jr, et al. A randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation. Int J Antimicrob Agents 2012;39:240-246.
-
(2012)
Int J Antimicrob Agents
, vol.39
, pp. 240-246
-
-
Nicholson, S.C.1
Welte, T.2
File, T.M.3
-
25
-
-
84902958324
-
A phase 3 randomized double-blind comparison of ceftobiprole medocaril versus ceftazidime plus linezolid for the treatment of hospital-acquired pneumonia
-
Awad SS, Rodriguez AH, Chuang YC, et al. A phase 3 randomized double-blind comparison of ceftobiprole medocaril versus ceftazidime plus linezolid for the treatment of hospital-acquired pneumonia. Clin Infect Dis 2014;59:51-61. Efficacy and safety of ceftobiprole medocaril compared with ceftazidime plus blinezolid for the treatment of HAP.
-
(2014)
Clin Infect Dis
, vol.59
, pp. 51-61
-
-
Awad, S.S.1
Rodriguez, A.H.2
Chuang, Y.C.3
-
26
-
-
84940938031
-
Telavancin demonstrates activity against methicillin-resistant Staphylococcus aureus isolates with reduced susceptibility to vancomycin, daptomycin, and linezolid in broth microdilution MIC and one-compartment pharmacokinetic/pharmacodynamic models
-
Smith JR, Barber KE, Hallesy J, et al. Telavancin demonstrates activity against methicillin-resistant Staphylococcus aureus isolates with reduced susceptibility to vancomycin, daptomycin, and linezolid in broth microdilution MIC and one-compartment pharmacokinetic/pharmacodynamic models. Antimicrob Agents Chemother 2015;59:5529-5534.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 5529-5534
-
-
Smith, J.R.1
Barber, K.E.2
Hallesy, J.3
-
27
-
-
77957873011
-
Telavancin activity against Gram-positive bacteria isolated from respiratory tract specimens of patients with nosocomial pneumonia
-
Pfaller MA, Mendes RE, Sader HS, Jones RN. Telavancin activity against Gram-positive bacteria isolated from respiratory tract specimens of patients with nosocomial pneumonia. J Antimicrob Chemother 2010;65:2396-2404.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 2396-2404
-
-
Pfaller, M.A.1
Mendes, R.E.2
Sader, H.S.3
Jones, R.N.4
-
28
-
-
77951748893
-
New lipoglycopeptides: A comparative review of dalbavancin, oritavancin and telavancin
-
Zhanel GG, Calic D, Schweizer F, et al. New lipoglycopeptides: a comparative review of dalbavancin, oritavancin and telavancin. Drugs 2010;70:859-886;
-
(2010)
Drugs
, vol.70
, pp. 859-886
-
-
Zhanel, G.G.1
Calic, D.2
Schweizer, F.3
-
29
-
-
84977964857
-
Erratum
-
Erratum in: Drugs 2011;71:526.
-
(2011)
Drugs
, vol.71
, pp. 526
-
-
-
30
-
-
46249092190
-
Telavancin penetration into human epithelial lining fluid determined by population pharmacokinetic modeling and Monte Carlo simulation
-
Lodise TP Jr, Gotfried M, Barriere S, Drusano GL. Telavancin penetration into human epithelial lining fluid determined by population pharmacokinetic modeling and Monte Carlo simulation. Antimicrob Agents Chemother 2008;52:2300-2304.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2300-2304
-
-
Lodise, T.P.1
Gotfried, M.2
Barriere, S.3
Drusano, G.L.4
-
31
-
-
79951656334
-
Telavancin versus vancomycin for hospital-acquired pneumonia due to gram-positive pathogens
-
Rubinstein E, Lalani T, Corey GR, et al., ATTAIN Study Group. Telavancin versus vancomycin for hospital-acquired pneumonia due to gram-positive pathogens. Clin Infect Dis 2011;52:31-40.
-
(2011)
Clin Infect Dis
, vol.52
, pp. 31-40
-
-
Rubinstein, E.1
Lalani, T.2
Corey, G.R.3
-
32
-
-
84865080997
-
Efficacy and safety of telavancin in clinical trials: A systematic review and meta-analysis
-
Polyzos KA, Mavros MN, Vardakas KZ, et al. Efficacy and safety of telavancin in clinical trials: a systematic review and meta-analysis. PLoS One 2012;7:e41870.
-
(2012)
PLoS One
, vol.7
, pp. e41870
-
-
Polyzos, K.A.1
Mavros, M.N.2
Vardakas, K.Z.3
-
33
-
-
84899507592
-
The ATTAIN trials: Efficacy and safety of telavancin compared with vancomycin for the treatment of hospital-acquired and ventilator-associated bacterial pneumonia
-
Barriere SL. The ATTAIN trials: efficacy and safety of telavancin compared with vancomycin for the treatment of hospital-acquired and ventilator-associated bacterial pneumonia. Future Microbiol 2014;9:281-289.
-
(2014)
Future Microbiol
, vol.9
, pp. 281-289
-
-
Barriere, S.L.1
-
34
-
-
84896450041
-
Analysis of Phase 3 telavancin nosocomial pneumonia data excluding patients with severe renal impairment and acute renal failure
-
Torres A, Rubinstein E, Corey GR, et al. Analysis of Phase 3 telavancin nosocomial pneumonia data excluding patients with severe renal impairment and acute renal failure. J Antimicrob Chemother 2014;69:1119-1126. Post-hoc analysis of data from the ATTAIN studies supporting the use of telavancin for the treatment of nosocomial pneumonia in patients with normal renal function.
-
(2014)
J Antimicrob Chemother
, vol.69
, pp. 1119-1126
-
-
Torres, A.1
Rubinstein, E.2
Corey, G.R.3
-
36
-
-
84954494697
-
In vitro activities of ceftazidime-avibactam, aztreonam-avibactam, and a panel of older and contemporary antimicrobial agents against carbapenemase-producing Gram-negative bacilli
-
Vasoo S, Cunningham SA, Cole NC, et al. In vitro activities of ceftazidime-avibactam, aztreonam-avibactam, and a panel of older and contemporary antimicrobial agents against carbapenemase-producing Gram-negative bacilli. Antimicrob Agents Chemother 2015;59:7842-7846. In-vitro antibacterial activity of avibactam in combination with different antimicrobials.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 7842-7846
-
-
Vasoo, S.1
Cunningham, S.A.2
Cole, N.C.3
-
37
-
-
84906074469
-
Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against b-lactamaseproducing Enterobacteriaceae and Pseudomonas aeruginosa
-
Keepers TR, Gomez M, Celeri C, et al. Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against b-lactamaseproducing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2014;58:5297-5305. In-vitro activity of ceftazidime/avibactam against Enterobacteriacae and Pseudomonas aeruginosa.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 5297-5305
-
-
Keepers, T.R.1
Gomez, M.2
Celeri, C.3
-
38
-
-
84928202650
-
Activity ofavibactam against Enterobacter cloacae producing an extended-spectrum class C b-lactamase enzyme
-
Lahiri SD, Giacobbe RA, Johnstone MR, Alm RA. Activity ofavibactam against Enterobacter cloacae producing an extended-spectrum class C b-lactamase enzyme. J Antimicrob Chemother 2014;69:2942-2946.
-
(2014)
J Antimicrob Chemother
, vol.69
, pp. 2942-2946
-
-
Lahiri, S.D.1
Giacobbe, R.A.2
Johnstone, M.R.3
Alm, R.A.4
-
39
-
-
84908439740
-
Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-b-lactamase-producing Enterobacteriaceae in a murine thigh infection model
-
MacVane SH, Crandon JL, Nichols WW, Nicolau DP. Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-b-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother 2014;58:7007-7009.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 7007-7009
-
-
MacVane, S.H.1
Crandon, J.L.2
Nichols, W.W.3
Nicolau, D.P.4
-
40
-
-
84977964862
-
Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects
-
Das S, Li J, Armstrong J, et al. Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects. Pharmacol Res Perspect 2015;3:e00172.
-
(2015)
Pharmacol Res Perspect
, vol.3
, pp. e00172
-
-
Das, S.1
Li, J.2
Armstrong, J.3
-
41
-
-
84937627900
-
Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers
-
Tominaga N, Edeki T, Li J, et al. Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers. J Infect Chemother 2015;21:551-558.
-
(2015)
J Infect Chemother
, vol.21
, pp. 551-558
-
-
Tominaga, N.1
Edeki, T.2
Li, J.3
-
42
-
-
84940007604
-
Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers: Results of two randomized, placebocontrolled studies
-
Merdjan H, Rangaraju M, Tarral A. Safety and pharmacokinetics of single and multiple ascending doses of avibactam alone and in combination with ceftazidime in healthy male volunteers: results of two randomized, placebocontrolled studies. Clin Drug Invest 2015;35:307-317.
-
(2015)
Clin Drug Invest
, vol.35
, pp. 307-317
-
-
Merdjan, H.1
Rangaraju, M.2
Tarral, A.3
-
43
-
-
84942903035
-
First report of ceftazidimeavibactam resistance in a KPC-3-expressing Klebsiella pneumoniae isolate
-
Humphries RM, Yang S, Hemarajata P, et al. First report of ceftazidimeavibactam resistance in a KPC-3-expressing Klebsiella pneumoniae isolate. Antimicrob Agents Chemother 2015;59:6605-6607.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 6605-6607
-
-
Humphries, R.M.1
Yang, S.2
Hemarajata, P.3
-
44
-
-
84921797970
-
Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: Resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa
-
Winkler ML, Papp-Wallace KM, Hujer AM, et al. Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2015;59:1020-1029.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 1020-1029
-
-
Winkler, M.L.1
Papp-Wallace, K.M.2
Hujer, A.M.3
-
45
-
-
84911896976
-
Microbiological interaction studies between ceftazidime-avibactam and pulmonary surfactant and between ceftazidime-avibactam and antibacterial agents of other classes
-
Dallow J, Otterson LG, Huband MD, et al. Microbiological interaction studies between ceftazidime-avibactam and pulmonary surfactant and between ceftazidime-avibactam and antibacterial agents of other classes. Int J Antimicrob Agents 2014;44:552-556.
-
(2014)
Int J Antimicrob Agents
, vol.44
, pp. 552-556
-
-
Dallow, J.1
Otterson, L.G.2
Huband, M.D.3
-
46
-
-
84896844160
-
Efficacies of ceftazidime-avibactam and ceftazidime against Pseudomonas aeruginosa in a murine lung infection model
-
Housman ST, Crandon JL, Nichols WW, Nicolau DP. Efficacies of ceftazidime-avibactam and ceftazidime against Pseudomonas aeruginosa in a murine lung infection model. Antimicrob Agents Chemother 2014;58:1365-1371.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 1365-1371
-
-
Housman, S.T.1
Crandon, J.L.2
Nichols, W.W.3
Nicolau, D.P.4
-
47
-
-
33847621194
-
In vitro and in vivo activities of a new cephalosporin, FR264205, against Pseudomonas aeruginosa
-
Takeda S, Nakai T, Wakai Y, et al. In vitro and in vivo activities of a new cephalosporin, FR264205, against Pseudomonas aeruginosa. Antimicrob Agents Chemother 2007;51:826-830.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 826-830
-
-
Takeda, S.1
Nakai, T.2
Wakai, Y.3
-
48
-
-
84902087476
-
Ceftolozane/tazobactam activity tested against Gram-negative bacterial isolates from hospitalised patients with pneumonia in US and European medical centres (2012)
-
Farrell DJ, Sader HS, Flamm RK, Jones RN. Ceftolozane/tazobactam activity tested against Gram-negative bacterial isolates from hospitalised patients with pneumonia in US and European medical centres (2012). Int J Antimicrob Agents 2014;43:533-539. In-vitro activity of ceftolozane/tazobactam against Enterobacteriacae and P. aeruginosa.
-
(2014)
Int J Antimicrob Agents
, vol.43
, pp. 533-539
-
-
Farrell, D.J.1
Sader, H.S.2
Flamm, R.K.3
Jones, R.N.4
-
49
-
-
84921029928
-
Antimicrobial activity of ceftolozane/tazobactam tested against Pseudomonas aeruginosa and Enterobacteriaceae with various resistance patterns isolated in European hospitals (2011-12)
-
Sader HS, Farrell DJ, Castanheira M, et al. Antimicrobial activity of ceftolozane/tazobactam tested against Pseudomonas aeruginosa and Enterobacteriaceae with various resistance patterns isolated in European hospitals (2011-12). J Antimicrob Chemother 2014;69:2713-2722.
-
(2014)
J Antimicrob Chemother
, vol.69
, pp. 2713-2722
-
-
Sader, H.S.1
Farrell, D.J.2
Castanheira, M.3
-
50
-
-
84866599592
-
Intrapulmonary penetration of ceftolozane/tazobactam and piperacillin/tazobactam in healthy adult subjects
-
Chandorkar G, Huntington JA, Gotfried MH, et al. Intrapulmonary penetration of ceftolozane/tazobactam and piperacillin/tazobactam in healthy adult subjects. J Antimicrob Chemother 2012;67:2463-2469.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 2463-2469
-
-
Chandorkar, G.1
Huntington, J.A.2
Gotfried, M.H.3
-
51
-
-
84954153001
-
Ceftolozane/tazobactam pharmacokinetic/pharmacodynamic-derived dose justification for phase 3 studies in patients with nosocomial pneumonia
-
Xiao AJ, Miller BW, Huntington JA, Nicolau DP. Ceftolozane/tazobactam pharmacokinetic/pharmacodynamic-derived dose justification for phase 3 studies in patients with nosocomial pneumonia. J Clin Pharmacol 2016;56:56-66. PK/PD analysis supporting the use of high-dose caftolozane/tazobactam for the treatment of pneumonia.
-
(2016)
J Clin Pharmacol
, vol.56
, pp. 56-66
-
-
Xiao, A.J.1
Miller, B.W.2
Huntington, J.A.3
Nicolau, D.P.4
-
53
-
-
84912083877
-
Platelet profile in patients with acute bacterial skin and skin structure infections receiving tedizolid or linezolid: Findings from the phase 3 ESTABLISH clinical trials
-
Lodise TP, Fang E, Minassian SL, Prokocimer PG. Platelet profile in patients with acute bacterial skin and skin structure infections receiving tedizolid or linezolid: findings from the phase 3 ESTABLISH clinical trials. Antimicrob Agents Chemother 2014;58:7198-7204.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 7198-7204
-
-
Lodise, T.P.1
Fang, E.2
Minassian, S.L.3
Prokocimer, P.G.4
-
54
-
-
84921933187
-
Analysis of the phase 3 ESTABLISH trials of tedizolid versus linezolid in acute bacterial skin and skin structure infections
-
Shorr AF, Lodise TP, Corey GR, et al. Analysis of the phase 3 ESTABLISH trials of tedizolid versus linezolid in acute bacterial skin and skin structure infections. Antimicrob Agents Chemother 2015;59:864-871.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 864-871
-
-
Shorr, A.F.1
Lodise, T.P.2
Corey, G.R.3
-
55
-
-
84255201091
-
The oxazolidinones: Past, present, and future
-
Shaw KJ, Barbachyn MR. The oxazolidinones: past, present, and future. Ann NY Acad Sci 2011;1241:48-70.
-
(2011)
Ann NY Acad Sci
, vol.1241
, pp. 48-70
-
-
Shaw, K.J.1
Barbachyn, M.R.2
-
56
-
-
84908266611
-
Tedizolid population pharmacokinetics, exposure response, and target attainment
-
Flanagan S, Passarell J, Lu Q. Tedizolid population pharmacokinetics, exposure response, and target attainment. Antimicrob Agents Chemother 2014;58:6462-6470.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6462-6470
-
-
Flanagan, S.1
Passarell, J.2
Lu, Q.3
-
57
-
-
84942941695
-
In vitro activities of tedizolid and linezolid against Gram-positive cocci associated with acute bacterial skin and skin structure infections and pneumonia
-
Chen KH, Huang YT, Liao CH, et al. In vitro activities of tedizolid and linezolid against Gram-positive cocci associated with acute bacterial skin and skin structure infections and pneumonia. Antimicrob Agents Chemother 2015;59:6262-6265.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 6262-6265
-
-
Chen, K.H.1
Huang, Y.T.2
Liao, C.H.3
-
58
-
-
84861120393
-
Pharmacokinetics and pulmonary disposition of tedizolid and linezolid in a murine pneumonia model under variable conditions
-
Keel RA, Crandon JL, Nicolau DP. Pharmacokinetics and pulmonary disposition of tedizolid and linezolid in a murine pneumonia model under variable conditions. Antimicrob Agents Chemother 2012;56:3420-3422.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3420-3422
-
-
Keel, R.A.1
Crandon, J.L.2
Nicolau, D.P.3
-
59
-
-
84892183660
-
Use of pharmacokinetic/pharmacodynamic systems analyses to inform dose selection of tedizolid phosphate
-
Lodise TP, Drusano GL. Use of pharmacokinetic/pharmacodynamic systems analyses to inform dose selection of tedizolid phosphate. Clin Infect Dis 2014;58(Suppl 1):S28-S34. PK/PD study supporting the potential role of tedizolid for the treatment of respiratory tract infections.
-
(2014)
Clin Infect Dis
, vol.58
, pp. S28-S34
-
-
Lodise, T.P.1
Drusano, G.L.2
-
60
-
-
84860162874
-
Comparative in vivo efficacies of epithelial lining fluid exposures of tedizolid, linezolid, and vancomycin for methicillin-resistant Staphylococcus aureus in a mouse pneumonia model
-
Tessier PR, Keel RA, Hagihara M, et al. Comparative in vivo efficacies of epithelial lining fluid exposures of tedizolid, linezolid, and vancomycin for methicillin-resistant Staphylococcus aureus in a mouse pneumonia model. Antimicrob Agents Chemother 2012;56:2342-2346.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 2342-2346
-
-
Tessier, P.R.1
Keel, R.A.2
Hagihara, M.3
-
61
-
-
84865436255
-
Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae
-
Choi S, Im W, Bartizal K. Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother 2012;56:4713-4717.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4713-4717
-
-
Choi, S.1
Im, W.2
Bartizal, K.3
-
62
-
-
84869837236
-
Activity of delafloxacin against methicillin-resistant Staphylococcus aureus: Resistance selection and characterization
-
Remy JM, Tow-Keogh CA, McConnell TS, et al. Activity of delafloxacin against methicillin-resistant Staphylococcus aureus: resistance selection and characterization. J Antimicrob Chemother 2012;67:2814-2820.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 2814-2820
-
-
Remy, J.M.1
Tow-Keogh, C.A.2
McConnell, T.S.3
-
63
-
-
3042536020
-
In vitro and bactericidal activities of ABT-492, a novel fluoroquinolone, against Gram-positive and Gramnegative organisms
-
Almer LS, Hoffrage JB, Keller EL, et al. In vitro and bactericidal activities of ABT-492, a novel fluoroquinolone, against Gram-positive and Gramnegative organisms. Antimicrob Agents Chemother 2004;48:2771-2777.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2771-2777
-
-
Almer, L.S.1
Hoffrage, J.B.2
Keller, E.L.3
-
64
-
-
0347992030
-
In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis
-
Gunderson SM, Hayes RA, Quinn JP, Danziger LH. In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob Agents Chemother 2004;48:203-208.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 203-208
-
-
Gunderson, S.M.1
Hayes, R.A.2
Quinn, J.P.3
Danziger, L.H.4
-
65
-
-
84923041556
-
A phase 2 study of the safety and efficacy of oral delafloxacin (DLX) in community acquired pneumonia (CAP)
-
San Diego, California, USA, Accessed 12 January 2016
-
Longcor J, Hopkins S, Wickler M, Laurence L. A phase 2 study of the safety and efficacy of oral delafloxacin (DLX) in community acquired pneumonia (CAP). Presented at ID Week 2012; San Diego, California, USA. https://idsa.confex.com/idsa/.../Paper37764.html. [Accessed 12 January 2016]
-
(2012)
ID Week
-
-
Longcor, J.1
Hopkins, S.2
Wickler, M.3
Laurence, L.4
-
66
-
-
84923041556
-
A phase 2 safety and efficacy study of oral delafloxacin (DLX) in subjects with acute bacterial exacerbation of chronic bronchitis (ABECB)
-
San Diego, California, USA, Accessed 12 January 2016
-
Longcor J, Hopkins S, Wickler M, Laurence L. A phase 2 safety and efficacy study of oral delafloxacin (DLX) in subjects with acute bacterial exacerbation of chronic bronchitis (ABECB). Presented at ID Week 2012; San Diego, California, USA. https://idsa.confex.com/idsa/.../Paper37662.html. [Accessed 12 January 2016]
-
(2012)
ID Week
-
-
Longcor, J.1
Hopkins, S.2
Wickler, M.3
Laurence, L.4
-
67
-
-
84916910184
-
A randomized phase 2 study comparing two doses of delafloxacin with tigecycline in adults with complicated skin and skin-structure infections
-
O'Riordan W, Mehra P, Manos P, et al. A randomized phase 2 study comparing two doses of delafloxacin with tigecycline in adults with complicated skin and skin-structure infections. Int J Infect Dis 2015;30:67-73.
-
(2015)
Int J Infect Dis
, vol.30
, pp. 67-73
-
-
O'Riordan, W.1
Mehra, P.2
Manos, P.3
-
68
-
-
84929593950
-
A thorough QT study to evaluate the effects of therapeutic and supratherapeutic doses of delafloxacin on cardiac repolarization
-
Litwin JS, Benedict MS, Thorn MD, et al. A thorough QT study to evaluate the effects of therapeutic and supratherapeutic doses of delafloxacin on cardiac repolarization. Antimicrob Agents Chemother 2015;59:3469-3473.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 3469-3473
-
-
Litwin, J.S.1
Benedict, M.S.2
Thorn, M.D.3
-
69
-
-
84863012847
-
Fluorocyclines.2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy
-
Clark RB, Hunt DK, He M, et al. Fluorocyclines.2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy. J Med Chem 2012;55:606-622.
-
(2012)
J Med Chem
, vol.55
, pp. 606-622
-
-
Clark, R.B.1
Hunt, D.K.2
He, M.3
-
70
-
-
84885921693
-
Antibacterial activity of eravacycline (TP-434), a novel fluorocycline, against hospital and community pathogens
-
Sutcliffe JA, O'Brien W, Fyfe C, Grossman TH. Antibacterial activity of eravacycline (TP-434), a novel fluorocycline, against hospital and community pathogens. Antimicrob Agents Chemother 2013;57:5548-5558.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 5548-5558
-
-
Sutcliffe, J.A.1
O'Brien, W.2
Fyfe, C.3
Grossman, T.H.4
-
71
-
-
84923255578
-
Activity of eravacycline against Enterobacteriaceae and Acinetobacter baumannii, including multidrug-resistant isolates, from New York City
-
Abdallah M, Olafisoye O, Cortes C, et al. Activity of eravacycline against Enterobacteriaceae and Acinetobacter baumannii, including multidrug-resistant isolates, from New York City. Antimicrob Agents Chemother 2015;59:1802-1805. In vitro activity of eravacycline against Enterobacteriacae and A. baumanii.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 1802-1805
-
-
Abdallah, M.1
Olafisoye, O.2
Cortes, C.3
-
72
-
-
84911871699
-
Eravacycline for the treatment of intra-abdominal infections
-
Bassetti M, Righi E. Eravacycline for the treatment of intra-abdominal infections. Expert Opin Investig Drugs 2014;23:1575-1584.
-
(2014)
Expert Opin Investig Drugs
, vol.23
, pp. 1575-1584
-
-
Bassetti, M.1
Righi, E.2
-
73
-
-
84896993164
-
Phase I, open-label, safety and pharmacokinetic study to assess bronchopulmonary disposition of intravenous eravacycline in healthy men and women
-
Connors KP, Housman ST, Pope JS, et al. Phase I, open-label, safety and pharmacokinetic study to assess bronchopulmonary disposition of intravenous eravacycline in healthy men and women. Antimicrob Agents Chemother 2014;58:2113-2118. Phase I study supporting the potential role of eravacycline for the treatment of respiratory tract infections.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 2113-2118
-
-
Connors, K.P.1
Housman, S.T.2
Pope, J.S.3
-
74
-
-
84931262480
-
Eravacycline (TP-434) is efficacious in animal models of infection
-
Grossman TH, Murphy TM, Slee AM, et al. Eravacycline (TP-434) is efficacious in animal models of infection. Antimicrob Agents Chemother 2015;59:2567-2571.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 2567-2571
-
-
Grossman, T.H.1
Murphy, T.M.2
Slee, A.M.3
|