STEM tomography reveals that the canalicular system and α-granules remain separate compartments during early secretion stages in blood platelets

Journal of Thrombosis and Haemostasis

Volumn 14, Issue 3, 2016, Pages 572-584

  Pokrovskaya, I D ^a   Aronova, M A ^b   Kamykowski, J A ^a   Prince, A A ^a   Hoyne, J D ^b   Calco, G N ^b   Kuo, B C ^b   He, Q ^b   Leapman, R D ^b   Storrie, B ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

Blood platelets; Cytoplasmic granules; Electron microscope tomography; Hemostasis; Platelet activation

Indexed keywords

ARTICLE; CELL DENSITY; CELL FUSION; CELL GRANULE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FREEZING; PLATELET ALPHA GRANULE; PLATELET CANALICULAR SYSTEM; PRIORITY JOURNAL; SCANNING TRANSMISSION ELECTRON MICROSCOPY; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE MEMBRANE; THROMBOCYTE RELEASE REACTION; THROMBOCYTE STRUCTURE; CELL MEMBRANE; CRYOELECTRON MICROSCOPY; HUMAN; INTRACELLULAR MEMBRANE; MEMBRANE FUSION; PROCEDURES; SECRETION (PROCESS); SECRETORY VESICLE; TIME FACTOR; TISSUE FIXATION; ULTRASTRUCTURE;

BLOOD PLATELETS; CELL MEMBRANE; CRYOELECTRON MICROSCOPY; CYTOPLASMIC GRANULES; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE FUSION; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; PLATELET ACTIVATION; SECRETORY VESICLES; TIME FACTORS; TISSUE FIXATION;

EID: 84960100526     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.13225     Document Type: Article

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