메뉴 건너뛰기




Volumn 8, Issue 1, 2016, Pages

Development of liposomal ciprofloxacin to treat lung infections

Author keywords

Bronchiectasis; Ciprofloxacin; Cystic fibrosis; Formulation; Inhalation delivery; Liposomes; Lung infection; Non tuberculous mycobacteria

Indexed keywords

CIPROFLOXACIN; LIPOSOMAL CIPROFLOXACIN; UNCLASSIFIED DRUG;

EID: 84960078694     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics8010006     Document Type: Review
Times cited : (147)

References (83)
  • 1
    • 84890469602 scopus 로고    scopus 로고
    • Inhaled Antibiotics to Treat Lung Infection. Pharm
    • [CrossRef][PubMed]
    • Cipolla, D.; Chan, H.-K. Inhaled Antibiotics to Treat Lung Infection. Pharm. Patent Analyst. 2013, 2, 647–663. [CrossRef][PubMed]
    • (2013) Patent Analyst , vol.2 , pp. 647-663
    • Cipolla, D.1    Chan, H.-K.2
  • 2
    • 84930088821 scopus 로고    scopus 로고
    • Inhaled antimicrobial therapy - barriers to effective treatment.
    • [CrossRef][PubMed]
    • Weers, J. Inhaled antimicrobial therapy - barriers to effective treatment. Adv. Drug Deliv. Rev. 2015, 85, 24–43. [CrossRef][PubMed]
    • (2015) Adv. Drug Deliv. Rev , vol.85 , pp. 24-43
    • Weers, J.1
  • 4
    • 84910096952 scopus 로고    scopus 로고
    • Aminoglycoside-Induced Nephrotoxicity
    • [CrossRef][PubMed]
    • Wargo, K.A.; Edwards, J.D. Aminoglycoside-Induced Nephrotoxicity. J. Pharm. Pract. 2014, 27, 573–577. [CrossRef][PubMed]
    • (2014) J. Pharm. Pract , vol.27 , pp. 573-577
    • Wargo, K.A.1    Edwards, J.D.2
  • 5
    • 0028274211 scopus 로고
    • Treatment of severe pneumonia in hospitalized patients: Results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. Antimicrob
    • [CrossRef][PubMed]
    • Fink, M.P.; Snydman, D.R.; Niederman, M.S.; Leeper, K.V., Jr.; Johnson, R.H.; Heard, S.O.; Wunderink, R.G.; Caldwell, J.W.; Schentag, J.J.; Siami, G.A. et al. Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. Antimicrob. Agents Chemother. 1994, 38, 547–557. [CrossRef][PubMed]
    • (1994) Agents Chemother , vol.38 , pp. 547-557
    • Fink, M.P.1    Snydman, D.R.2    Niederman, M.S.3    Leeper, K.V.4    Johnson, R.H.5    Heard, S.O.6    Wunderink, R.G.7    Caldwell, J.W.8    Schentag, J.J.9    Siami, G.A.10
  • 6
    • 0024417053 scopus 로고
    • Evaluation of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections. Impact of plasma concentrations, organism, minimum inhibitory concentration, and clinical condition on bacterial eradication.
    • [CrossRef][PubMed]
    • Peloquin, C.A.; Cumbo, T.J.; Nix, D.E.; Sands, M.F.; Schentag, J.J. Evaluation of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections. Impact of plasma concentrations, organism, minimum inhibitory concentration, and clinical condition on bacterial eradication. Arch. Intern Med. 1989, 149, 2269–2273. [CrossRef][PubMed]
    • (1989) Arch. Intern Med , vol.149 , pp. 2269-2273
    • Peloquin, C.A.1    Cumbo, T.J.2    Nix, D.E.3    Sands, M.F.4    Schentag, J.J.5
  • 7
    • 0031751627 scopus 로고    scopus 로고
    • MIC-based interspecies prediction of the antimicrobial effects of ciprofloxacin on bacteria of different susceptibilities in an in vitro dynamic model. Antimicrob
    • [PubMed]
    • Firsov, A.A.; Vostrov, S.N.; Shevchenko, A.A.; Zinner, S.H.; Cornaglia, G.; Portnoy, Y.A. MIC-based interspecies prediction of the antimicrobial effects of ciprofloxacin on bacteria of different susceptibilities in an in vitro dynamic model. Antimicrob. Agents Chemother. 1998, 42, 2848–2852. [PubMed]
    • (1998) Agents Chemother , vol.42 , pp. 2848-2852
    • Firsov, A.A.1    Vostrov, S.N.2    Shevchenko, A.A.3    Zinner, S.H.4    Cornaglia, G.5    Portnoy, Y.A.6
  • 8
    • 0027161344 scopus 로고
    • Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients. Antimicrob
    • [CrossRef][PubMed]
    • Forrest, A.; Nix, D.E.; Ballow, C.H.; Goss, T.F.; Birmingham, M.C.; Schentag, J.J. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients. Antimicrob. Agents Chemother. 1993, 37, 1073–1081. [CrossRef][PubMed]
    • (1993) Agents Chemother , vol.37 , pp. 1073-1081
    • Forrest, A.1    Nix, D.E.2    Ballow, C.H.3    Goss, T.F.4    Birmingham, M.C.5    Schentag, J.J.6
  • 9
    • 78650214408 scopus 로고    scopus 로고
    • Inhaled liposomal ciprofloxacin: Once a day management of respiratory infections
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Bruinenberg, P.; Blanchard, J.D.; Cipolla, D.C.; Dayton, F.; Mudumba, S.; Gonda, I. Inhaled liposomal ciprofloxacin: Once a day management of respiratory infections. In Proceedings of Respiratory Drug Delivery 2010; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2010; pp. 73–81.
    • (2010) Proceedings of Respiratory Drug Delivery 2010 , pp. 73-81
    • Bruinenberg, P.1    Blanchard, J.D.2    Cipolla, D.C.3    Dayton, F.4    Mudumba, S.5    Gonda, I.6
  • 10
    • 84872120268 scopus 로고    scopus 로고
    • Safety, Tolerability, Pharmacokinetics and Antimicrobial Activity of Inhaled Liposomal Ciprofloxacin Formulations in Humans
    • Bruinenberg, P.; Serisier, D.; Cipolla, D.; Blanchard, J. Safety, Tolerability, Pharmacokinetics and Antimicrobial Activity of Inhaled Liposomal Ciprofloxacin Formulations in Humans. Pediatr. Pulmonol. 2010, 45, 354.
    • (2010) Pediatr. Pulmonol , vol.45 , pp. 354
    • Bruinenberg, P.1    Serisier, D.2    Cipolla, D.3    Blanchard, J.4
  • 11
  • 12
    • 2442526705 scopus 로고    scopus 로고
    • Clinically Feasible Biofilm Susceptibility Assay for Isolates of Pseudomonas aeruginosa from Patients with Cystic Fibrosis
    • [CrossRef][PubMed]
    • Moskowitz, S.M.; Foster, J.M.; Emerson, J.; Burns, J.L. Clinically Feasible Biofilm Susceptibility Assay for Isolates of Pseudomonas aeruginosa from Patients with Cystic Fibrosis. J. Clin. Microbiol. 2004, 42, 1915–1922. [CrossRef][PubMed]
    • (2004) J. Clin. Microbiol , vol.42 , pp. 1915-1922
    • Moskowitz, S.M.1    Foster, J.M.2    Emerson, J.3    Burns, J.L.4
  • 13
    • 84929017972 scopus 로고    scopus 로고
    • Management of bronchiectasis in adults
    • [CrossRef][PubMed]
    • Chalmers, J.D.; Aliberti, S.; Blasi, F. Management of bronchiectasis in adults. Eur. Respir. J. 2015, 45, 1446–1462. [CrossRef][PubMed]
    • (2015) Eur. Respir. J , vol.45 , pp. 1446-1462
    • Chalmers, J.D.1    Aliberti, S.2    Blasi, F.3
  • 14
    • 84867058563 scopus 로고    scopus 로고
    • Pseudomonas infection in chronic obstructive pulmonary disease
    • [CrossRef][PubMed]
    • Parameswaran, I.; Sethi, S. Pseudomonas infection in chronic obstructive pulmonary disease. Future Microbiol. 2012, 7, 1129–1132. [CrossRef][PubMed]
    • (2012) Future Microbiol , vol.7 , pp. 1129-1132
    • Parameswaran, I.1    Sethi, S.2
  • 15
    • 84946711281 scopus 로고    scopus 로고
    • Comprehensive Analysis of the Impact of Pseudomonas aeruginosa Colonization on Prognosis in Adult Bronchiectasis
    • Finch, S.; McDonnell, M.J.; Abo-Leyah, H.; Aliberti, S.; Chalmers, J.D. A Comprehensive Analysis of the Impact of Pseudomonas aeruginosa Colonization on Prognosis in Adult Bronchiectasis. Ann. Am. Thorac. Soc. 2015, 2, 1602–1611.
    • (2015) Ann. Am. Thorac. Soc , vol.2 , pp. 1602-1611
    • Finch, S.1    McDonnell, M.J.2    Abo-Leyah, H.3    Aliberti, S.4    Chalmers, J.5
  • 16
    • 33751243366 scopus 로고    scopus 로고
    • Addition of inhaled tobramycin to ciprofloxacin for acute exacerbations of Pseudomonas aeruginosa infection in adult bronchiectasis
    • [CrossRef][PubMed]
    • Bilton, D.; Henig, N.; Morrissey, B.; Gotfried, M. Addition of inhaled tobramycin to ciprofloxacin for acute exacerbations of Pseudomonas aeruginosa infection in adult bronchiectasis. Chest 2006, 130, 1503–1510. [CrossRef][PubMed]
    • (2006) Chest , vol.130 , pp. 1503-1510
    • Bilton, D.1    Henig, N.2    Morrissey, B.3    Gotfried, M.4
  • 17
    • 84908070796 scopus 로고    scopus 로고
    • Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): Two randomised double-blind, placebo-controlled phase 3 trials. Lancet Respir
    • [CrossRef]
    • Barker, A.F.; O’Donnell, A.E.; Flume, P.; Thompson, P.J.; Ruzi, J.D.; de Gracia, J.; Boersma, W.G.; De Soyza, A.; Shao, L.; Zhang, J. et al. Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): Two randomised double-blind, placebo-controlled phase 3 trials. Lancet Respir. Med. 2014, 2, 738–749. [CrossRef]
    • (2014) Med , vol.2 , pp. 738-749
    • Barker, A.F.1    O’Donnell, A.E.2    Flume, P.3    Thompson, P.J.4    Ruzi, J.D.5    De Gracia, J.6    Boersma, W.G.7    De Soyza, A.8    Shao, L.9    Zhang, J.10
  • 18
    • 84898994995 scopus 로고    scopus 로고
    • Inhaled colistin in patients with bronchiectasis and chronic Pseudomonas aeruginosa infection.
    • [CrossRef][PubMed]
    • Haworth, C.S.; Foweraker, J.E.; Wilkinson, P.; Kenyon, R.F.; Bilton, D. Inhaled colistin in patients with bronchiectasis and chronic Pseudomonas aeruginosa infection. Am. J. Respir. Crit. Care Med. 2014, 189, 975–982. [CrossRef][PubMed]
    • (2014) Am. J. Respir. Crit. Care Med , vol.189 , pp. 975-982
    • Haworth, C.S.1    Foweraker, J.E.2    Wilkinson, P.3    Kenyon, R.F.4    Bilton, D.5
  • 19
    • 84907046532 scopus 로고    scopus 로고
    • Antimicrobial treatment of non-cystic fibrosis bronchiectasis. Expert
    • [CrossRef][PubMed]
    • Grimwood, K.; Bell, S.C.; Chang, A.B. Antimicrobial treatment of non-cystic fibrosis bronchiectasis. Expert Rev. Anti-Infect. Ther. 2014, 12, 1277–1296. [CrossRef][PubMed]
    • (2014) Rev. Anti-Infect. Ther , vol.12 , pp. 1277-1296
    • Grimwood, K.1    Bell, S.C.2    Chang, A.B.3
  • 20
    • 84867114791 scopus 로고    scopus 로고
    • Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis
    • [CrossRef][PubMed]
    • Chalmers, J.D.; Smith, M.P.; McHugh, B.J.; Doherty, C.; Govan, J.R.; Hill, A.T. Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis. Am. J. Respir. Crit. Care Med. 2012, 186, 657–665. [CrossRef][PubMed]
    • (2012) Am. J. Respir. Crit. Care Med , vol.186 , pp. 657-665
    • Chalmers, J.D.1    Smith, M.P.2    McHugh, B.J.3    Doherty, C.4    Govan, J.R.5    Hill, A.T.6
  • 22
    • 84860200716 scopus 로고    scopus 로고
    • Prevalence of nontuberculosis mycobacterial lung disease in US Medicare beneficiaries
    • [CrossRef][PubMed]
    • Adjemian, J.; Olivier, K.N.; Seitz, A.E.; Holland, S.M.; Prevots, D.R. Prevalence of nontuberculosis mycobacterial lung disease in US Medicare beneficiaries. Am. J. Respir. Crit. Care Med. 2012, 185, 881–886. [CrossRef][PubMed]
    • (2012) Am. J. Respir. Crit. Care Med , vol.185 , pp. 881-886
    • Adjemian, J.1    Olivier, K.N.2    Seitz, A.E.3    Holland, S.M.4    Prevots, D.R.5
  • 25
    • 84930223841 scopus 로고    scopus 로고
    • Delivery of Aerosolized Liposomal Amikacin as a Novel Approach for the Treatment of Nontuberculous Mycobacteria in an Experimental Model of Pulmonary Infection
    • [CrossRef][PubMed]
    • Rose, S.J.; Neville, M.E.; Gupta, R.; Bermudez, L.E. Delivery of Aerosolized Liposomal Amikacin as a Novel Approach for the Treatment of Nontuberculous Mycobacteria in an Experimental Model of Pulmonary Infection. PLoS ONE 2014, 9, e108703. [CrossRef][PubMed]
    • (2014) Plos ONE , vol.9
    • Rose, S.J.1    Neville, M.E.2    Gupta, R.3    Bermudez, L.E.4
  • 28
    • 84960117374 scopus 로고    scopus 로고
    • Treatment of Mycobacterium avium subsp hominissuis (MAH) lung infection with liposome-encapsulated ciprofloxacin resulted in significant decrease in bacterial load in the lung
    • Bermudez, L.E.; Blanchard, J.D.; Hauck, L.; Gonda, I. Treatment of Mycobacterium avium subsp hominissuis (MAH) lung infection with liposome-encapsulated ciprofloxacin resulted in significant decrease in bacterial load in the lung. Am J Respir Crit Care Med. 2015, 191, A6293. Available online: http://investor.aradigm.com/releasedetail.cfm?releaseid=912485 (accessed on 31 December 2015).
    • (2015) Am J Respir Crit Care Med , vol.191
    • Bermudez, L.E.1    Blanchard, J.D.2    Hauck, L.3    Gonda, I.4
  • 29
    • 41149105955 scopus 로고    scopus 로고
    • Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections. J
    • [CrossRef][PubMed]
    • Meers, P.; Neville, M.; Malinin, V.; Scotto, A.W.; Sardaryan, G.; Kurumunda, R.; Mackinson, C.; James, G.; Fisher, S.; Perkins, W.R. Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections. J. Antimicrob. Chemo. 2008, 61, 859–868. [CrossRef][PubMed]
    • (2008) Antimicrob. Chemo , vol.61 , pp. 859-868
    • Meers, P.1    Neville, M.2    Malinin, V.3    Scotto, A.W.4    Sardaryan, G.5    Kurumunda, R.6    Mackinson, C.7    James, G.8    Fisher, S.9    Perkins, W.R.10
  • 30
    • 84881539706 scopus 로고    scopus 로고
    • Liposomal Formulations for Inhalation. Ther
    • [CrossRef][PubMed]
    • Cipolla, D.; Gonda, I.; Chan, H.-K. Liposomal Formulations for Inhalation. Ther. Deliv. 2013, 4, 1047–1072. [CrossRef][PubMed]
    • (2013) Deliv , vol.4 , pp. 1047-1072
    • Cipolla, D.1    Gonda, I.2    Chan, H.-K.3
  • 31
    • 84908226561 scopus 로고    scopus 로고
    • Lipid-based carriers for pulmonary products: Preclinical development and case studies in Humans. Adv. Drug Deliv
    • [CrossRef][PubMed]
    • Cipolla, D.; Shekunov, B.; Blanchard, J.; Hickey, T. Lipid-based carriers for pulmonary products: Preclinical development and case studies in Humans. Adv. Drug Deliv. Rev. 2014, 75, 53–80. [CrossRef][PubMed]
    • (2014) Rev , vol.75 , pp. 53-80
    • Cipolla, D.1    Shekunov, B.2    Blanchard, J.3    Hickey, T.4
  • 32
    • 84862173929 scopus 로고    scopus 로고
    • Liposomes, Niosomes and Proniosomes—A Critical Update of Their (Commercial) Development as Inhaled Products
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Cipolla, D.; Redelmeier, T.; Eastman, S.; Bruinenberg, P.; Gonda, I. Liposomes, Niosomes and Proniosomes—A Critical Update of Their (Commercial) Development as Inhaled Products. In Proceedings of Respiratory Drug Delivery Europe 2011; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2011; pp. 41–54.
    • (2011) Proceedings of Respiratory Drug Delivery Europe 2011 , pp. 41-54
    • Cipolla, D.1    Redelmeier, T.2    Eastman, S.3    Bruinenberg, P.4    Gonda, I.5
  • 33
    • 84872104346 scopus 로고    scopus 로고
    • The Development of Inhaled Liposome-Encapsulated Ciprofloxacin to Treat Cystic Fibrosis
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Yim, D.; Blanchard, J.D.; Mudumba, S.; Eastman, S.; Manda, K.; Redelmeier, T.; Farr, S. The Development of Inhaled Liposome-Encapsulated Ciprofloxacin to Treat Cystic Fibrosis. In Proceedings of Respiratory Drug Delivery 2006; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2006; pp. 425–428.
    • (2006) Proceedings of Respiratory Drug Delivery 2006 , pp. 425-428
    • Yim, D.1    Blanchard, J.D.2    Mudumba, S.3    Eastman, S.4    Manda, K.5    Redelmeier, T.6    Farr, S.7
  • 34
    • 0031973574 scopus 로고    scopus 로고
    • Antibacterial Efficacy Against an in Vivo Salmonella Typhimurium Infection Model and Pharmacokinetics of a Liposomal Ciprofloxacin Formulation.
    • [PubMed]
    • Webb, M.S.; Boman, N.L.; Wiseman, D.J.; Saxon, D.; Sutton, K.; Wong, K.F.; Logan, P.; Hope, M.J. Antibacterial Efficacy Against an in Vivo Salmonella Typhimurium Infection Model and Pharmacokinetics of a Liposomal Ciprofloxacin Formulation. Antimicrob. Agents Chemother. 1998, 42, 45–52. [PubMed]
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 45-52
    • Webb, M.S.1    Boman, N.L.2    Wiseman, D.J.3    Saxon, D.4    Sutton, K.5    Wong, K.F.6    Logan, P.7    Hope, M.J.8
  • 35
    • 0023265372 scopus 로고
    • Altered pharmacologic disposition of ciprofloxacin and vancomycin after single and multiple doses in rabbits. Antimicrob
    • [CrossRef][PubMed]
    • Barriere, S.L.; Kaatz, G.W.; Schaberg, D.R.; Fekety, R. Altered pharmacologic disposition of ciprofloxacin and vancomycin after single and multiple doses in rabbits. Antimicrob. Agents Chemother. 1987, 31, 1075–1078. [CrossRef][PubMed]
    • (1987) Agents Chemother , vol.31 , pp. 1075-1078
    • Barriere, S.L.1    Kaatz, G.W.2    Schaberg, D.R.3    Fekety, R.4
  • 36
    • 67649389315 scopus 로고    scopus 로고
    • Pulmonary Drug Delivery as a First Response to Bioterrorism
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Blanchard, J. Pulmonary Drug Delivery as a First Response to Bioterrorism. In Proceedings of Respiratory Drug Delivery 2006; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2006; pp. 73–82.
    • (2006) Proceedings of Respiratory Drug Delivery 2006 , pp. 73-82
    • Blanchard, J.1
  • 37
    • 1642313902 scopus 로고    scopus 로고
    • Liposome Delivery of Ciprofloxacin against Intracellular Francisella tularensis Infection
    • [CrossRef]
    • Wong, J.P.; Yang, H.; Blasetti, K.L.; Schnell, G.; Conley, J.; Schofield, L.N. Liposome Delivery of Ciprofloxacin against Intracellular Francisella tularensis Infection. J. Control. Release 2003, 92, 265–273. [CrossRef]
    • (2003) J. Control. Release , vol.92 , pp. 265-273
    • Wong, J.P.1    Yang, H.2    Blasetti, K.L.3    Schnell, G.4    Conley, J.5    Schofield, L.N.6
  • 38
    • 84872118822 scopus 로고    scopus 로고
    • Liposomal Nanoparticles Control the Uptake of Ciprofloxacin Across Respiratory
    • [CrossRef][PubMed]
    • Ong, H.X.; Traini, D.; Cipolla, D.; Gonda, I.; Bebawy, M.; Agus, H.; Young, P.Y. Liposomal Nanoparticles Control the Uptake of Ciprofloxacin Across Respiratory Epithelia. Pharm. Res. 2012, 29, 3335–3346. [CrossRef][PubMed]
    • (2012) Epithelia. Pharm. Res , vol.29 , pp. 3335-3346
    • Ong, H.X.1    Traini, D.2    Cipolla, D.3    Gonda, I.4    Bebawy, M.5    Agus, H.6    Young, P.Y.7
  • 39
    • 84896700415 scopus 로고    scopus 로고
    • In Vitro and ex Vivo Methods Predict the Enhanced Lung Residence Time of Liposomal Ciprofloxacin Formulations for Nebulisation.
    • [CrossRef][PubMed]
    • Ong, H.X.; Benaouda, F.; Traini, D.; Cipolla, D.; Gonda, I.; Forbes, B.; Young, P.M. In Vitro and ex Vivo Methods Predict the Enhanced Lung Residence Time of Liposomal Ciprofloxacin Formulations for Nebulisation. Eur. J. Pharm. Biopharm. 2014, 86, 83–89. [CrossRef][PubMed]
    • (2014) Eur. J. Pharm. Biopharm , vol.86 , pp. 83-89
    • Ong, H.X.1    Benaouda, F.2    Traini, D.3    Cipolla, D.4    Gonda, I.5    Forbes, B.6    Young, P.M.7
  • 41
    • 78650193027 scopus 로고    scopus 로고
    • Inhaled Liposomal Ciprofloxacin: In Vitro Properties and Aerosol Performance
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Cipolla, D.C.; Dayton, F.; Fulzele, S.; Gabatan, E.; Mudumba, S.; Yim, D.; Wu, H.; Zwolinski, R. Inhaled Liposomal Ciprofloxacin: In Vitro Properties and Aerosol Performance. In Proceedings of Respiratory Drug Delivery 2010; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2010; pp. 409–414.
    • (2010) Proceedings of Respiratory Drug Delivery 2010 , pp. 409-414
    • Cipolla, D.C.1    Dayton, F.2    Fulzele, S.3    Gabatan, E.4    Mudumba, S.5    Yim, D.6    Wu, H.7    Zwolinski, R.8
  • 42
    • 84881493541 scopus 로고    scopus 로고
    • Liposomal Ciprofloxacin for Inhalation Retains Integrity Following Nebulization
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Cipolla, D.; Wu, H.; Chan, J.; Chan, H.-K.; Gonda, I. Liposomal Ciprofloxacin for Inhalation Retains Integrity Following Nebulization. In Proceedings of Respiratory Drug Delivery Europe 2013; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2013; pp. 237–242.
    • (2013) Proceedings of Respiratory Drug Delivery Europe 2013 , pp. 237-242
    • Cipolla, D.1    Wu, H.2    Chan, J.3    Chan, H.-K.4    Gonda, I.5
  • 43
    • 84890527843 scopus 로고    scopus 로고
    • Development and characterization of an in vitro release assay for liposomal ciprofloxacin for inhalation. J
    • [CrossRef]
    • Cipolla, D.; Wu, H.; Eastman, S.; Redelmeier, T.; Gonda, I.; Chan, H.-K. Development and characterization of an in vitro release assay for liposomal ciprofloxacin for inhalation. J. Pharm. Sci. 2014, 103, 314–327. [CrossRef]
    • (2014) Pharm. Sci , vol.103 , pp. 314-327
    • Cipolla, D.1    Wu, H.2    Eastman, S.3    Redelmeier, T.4    Gonda, I.5    Chan, H.-K.6
  • 44
    • 0032102783 scopus 로고    scopus 로고
    • Regional lung deposition of nebulized liposome-encapsulated ciprofloxacin
    • [CrossRef]
    • Finlay, W.H.; Wong, J.P. Regional lung deposition of nebulized liposome-encapsulated ciprofloxacin. Int. J. Pharm. 1998, 167, 121–127. [CrossRef]
    • (1998) Int. J. Pharm , vol.167 , pp. 121-127
    • Finlay, W.H.1    Wong, J.P.2
  • 45
    • 0027377645 scopus 로고
    • Chemical stability of liposomes: Implications for their physical stability
    • [CrossRef]
    • Grit, M.; Crommelin, D.J.A. Chemical stability of liposomes: Implications for their physical stability. Chem. Phys. Lipids. 1993, 64, 3–18. [CrossRef]
    • (1993) Chem. Phys. Lipids , vol.64 , pp. 3-18
    • Grit, M.1    Crommelin, D.J.A.2
  • 46
    • 85026945439 scopus 로고    scopus 로고
    • Dual Release Ciprofloxacin for Inhalation (DRCFI) Improves Time to First Exacerbation in Bronchiectasis
    • Cipolla, D.; Gonda, I.; Serisier, D.; Bruinenberg, P. Dual Release Ciprofloxacin for Inhalation (DRCFI) Improves Time to First Exacerbation in Bronchiectasis. J. Aerosol. Med. Pulm. Drug Deliv. 2011, 24, A-27.
    • (2011) J. Aerosol. Med. Pulm. Drug Deliv , vol.24
    • Cipolla, D.1    Gonda, I.2    Serisier, D.3    Bruinenberg, P.4
  • 47
    • 0034670221 scopus 로고    scopus 로고
    • Cryo transmission electron microscopy of liposomes and related structures.
    • [CrossRef]
    • Almgren, M.; Edwards, K.; Karlsson, G. Cryo transmission electron microscopy of liposomes and related structures. Colloids Surf. A 2000, 174, 3–21. [CrossRef]
    • (2000) Colloids Surf. A , vol.174 , pp. 3-21
    • Almgren, M.1    Edwards, K.2    Karlsson, G.3
  • 48
    • 85026940952 scopus 로고    scopus 로고
    • FDA. Draft Guidance for Industry. Liposome Drug Products: Chemistry, Manufacturing, and Controls; Human Pharmacokinetics and Bioavailability; and Labeling Documentation October
    • FDA. Draft Guidance for Industry. Liposome Drug Products: Chemistry, Manufacturing, and Controls; Human Pharmacokinetics and Bioavailability; and Labeling Documentation October 2015. Available online: http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm 070570.pdf (accessed on 18 February 2016).
    • (2015)
  • 49
    • 85026940239 scopus 로고    scopus 로고
    • ICH Quality Guidelines
    • ICH Quality Guidelines. Available online: http://www.ich.org/products/guidelines/quality/article/ quality-guidelines.html.
  • 50
    • 84901246757 scopus 로고    scopus 로고
    • Liposome encapsulation of ciprofloxacin improves protection against highly virulent Francisella tularensis strain Schu S4. Antimicrob
    • [CrossRef][PubMed]
    • Hamblin, K.A.; Armstrong, S.J.; Barnes, K.B.; Davies, C.; Wong, J.P.; Blanchard, J.D.; Harding, S.V.; Simpson, A.J.; Atkins, H.S. Liposome encapsulation of ciprofloxacin improves protection against highly virulent Francisella tularensis strain Schu S4. Antimicrob. Agents Chemother. 2014, 58, 3053–3059. [CrossRef][PubMed]
    • (2014) Agents Chemother , vol.58 , pp. 3053-3059
    • Hamblin, K.A.1    Armstrong, S.J.2    Barnes, K.B.3    Davies, C.4    Wong, J.P.5    Blanchard, J.D.6    Harding, S.V.7    Simpson, A.J.8    Atkins, H.S.9
  • 53
    • 49049105150 scopus 로고    scopus 로고
    • Monitoring infection and inflammation in murine models of cystic fibrosis with magnetic resonance imaging.
    • [CrossRef][PubMed]
    • Sheth, V.R.; van Heeckeren, R.C.; Wilson, A.G.; van Heeckeren, A.M.; Pagel, M.D. Monitoring infection and inflammation in murine models of cystic fibrosis with magnetic resonance imaging. J. Magn. Reson. Imaging. 2008, 28, 527–532. [CrossRef][PubMed]
    • (2008) J. Magn. Reson. Imaging , vol.28 , pp. 527-532
    • Sheth, V.R.1    Van Heeckeren, R.C.2    Wilson, A.G.3    Van Heeckeren, A.M.4    Pagel, M.D.5
  • 56
    • 0034456375 scopus 로고    scopus 로고
    • Treatment of tularemia with ciprofloxacin.
    • [CrossRef][PubMed]
    • Chocarro, A.; Gonzalez, A.; Garcia, I. Treatment of tularemia with ciprofloxacin. Clin. Infect. Dis. 2000, 31, 623. [CrossRef][PubMed]
    • (2000) Clin. Infect. Dis , vol.31
    • Chocarro, A.1    Gonzalez, A.2    Garcia, I.3
  • 57
    • 45549101295 scopus 로고    scopus 로고
    • Tularemia: Current diagnosis and treatment options. Expert
    • [CrossRef][PubMed]
    • Hepburn, M.J.; Simpson, A.J.H. Tularemia: Current diagnosis and treatment options. Expert Rev. Anti-Infect. Ther. 2008, 6, 231–240. [CrossRef][PubMed]
    • (2008) Rev. Anti-Infect. Ther , vol.6 , pp. 231-240
    • Hepburn, M.J.1    Simpson, A.J.H.2
  • 58
    • 33646157745 scopus 로고    scopus 로고
    • Treatment of murine pneumonic Francisella tularensis infection with gatifloxacin, moxifloxacin or ciprofloxacin
    • [CrossRef][PubMed]
    • Steward, J.; Piercy, T.; Lever, M.S.; Simpson, A.J.H.; Brooks, T.J.G. Treatment of murine pneumonic Francisella tularensis infection with gatifloxacin, moxifloxacin or ciprofloxacin. Int. J. Antimicrob. Agents. 2006, 27, 439–443. [CrossRef][PubMed]
    • (2006) Int. J. Antimicrob. Agents , vol.27 , pp. 439-443
    • Steward, J.1    Piercy, T.2    Lever, M.S.3    Simpson, A.J.H.4    Brooks, T.J.G.5
  • 59
    • 0030997918 scopus 로고    scopus 로고
    • Aerosol delivery of liposome-encapsulated ciprofloxacin: Aerosol characterization and efficacy against Francisella tularensis infection in mice. Antimicrob
    • [PubMed]
    • Conley, J.; Yang, H.; Wilson, T.; Blasetti, K.; Di Ninno, V.; Schnell, G.; Wong, J.P. Aerosol delivery of liposome-encapsulated ciprofloxacin: Aerosol characterization and efficacy against Francisella tularensis infection in mice. Antimicrob. Agents Chemother. 1997, 41, 1288–1292. [PubMed]
    • (1997) Agents Chemother , vol.41 , pp. 1288-1292
    • Conley, J.1    Yang, H.2    Wilson, T.3    Blasetti, K.4    Di Ninno, V.5    Schnell, G.6    Wong, J.P.7
  • 60
    • 0027302804 scopus 로고
    • Liposome-encapsulated ciprofloxacin is effective in the protection and treatment of BALB/c mice against Francisella tularensis. J.
    • [CrossRef][PubMed]
    • Di Ninno, V.L.; Cherwanogrodzky, J.W.; Wong, J.P. Liposome-encapsulated ciprofloxacin is effective in the protection and treatment of BALB/c mice against Francisella tularensis. J. Infect. Dis. 1993, 168, 793–794. [CrossRef][PubMed]
    • (1993) Infect. Dis , vol.168 , pp. 793-794
    • Di Ninno, V.L.1    Cherwanogrodzky, J.W.2    Wong, J.P.3
  • 61
    • 84907181983 scopus 로고    scopus 로고
    • The Potential of Liposome-Encapsulated Ciprofloxacin as a Tularemia Therapy. Front. Cell Infect
    • [CrossRef][PubMed]
    • Hamblin, K.A.; Wong, J.P.; Blanchard, J.D.; Atkins, H.S. The Potential of Liposome-Encapsulated Ciprofloxacin as a Tularemia Therapy. Front. Cell Infect. Microbiol. 2014, 4, 79. [CrossRef][PubMed]
    • (2014) Microbiol , vol.4
    • Hamblin, K.A.1    Wong, J.P.2    Blanchard, J.D.3    Atkins, H.S.4
  • 62
    • 0017249009 scopus 로고
    • Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation.
    • [CrossRef]
    • Brain, J.D.; Knudson, D.E.; Sorokin, S.P.; Davis, M.A. Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation. Environ. Res. 1976, 11, 13–33. [CrossRef]
    • (1976) Environ. Res. , vol.11 , pp. 13-33
    • Brain, J.D.1    Knudson, D.E.2    Sorokin, S.P.3    Davis, M.A.4
  • 63
    • 84960190359 scopus 로고    scopus 로고
    • FDA. Draft Guidance for Industry. Animal models—Essential elements to address efficacy under the Animal Rule
    • FDA. Draft Guidance for Industry. Animal models—Essential elements to address efficacy under the Animal Rule. Available online: http://www.fda.gov/downloads/drugs/guidancecompliance regulatoryinformation/guidances/ucm399217.pdf (accessed on 18 February 2016).
  • 65
    • 21444435544 scopus 로고    scopus 로고
    • Correlation between ratio of serum doxycycline concentration to MIC and rapid decline of antibody levels during treatment of Q fever endocarditis.
    • [CrossRef][PubMed]
    • Rolain, J.M.; Boulos, A.; Mallet, M.N.; Raoult, D. Correlation between ratio of serum doxycycline concentration to MIC and rapid decline of antibody levels during treatment of Q fever endocarditis. Antimicrob. Agents Chemother. 2005, 49, 2673–2676. [CrossRef][PubMed]
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 2673-2676
    • Rolain, J.M.1    Boulos, A.2    Mallet, M.N.3    Raoult, D.4
  • 68
    • 84960190361 scopus 로고    scopus 로고
    • CDC Q fever
    • CDC Q fever. Available online: http://www.cdc.gov/qfever/index.html (accessed on 18 February 2016).
  • 69
    • 0033601740 scopus 로고    scopus 로고
    • Treatment of Q fever endocarditis: Comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine.
    • [CrossRef][PubMed]
    • Raoult, D.; Houpikian, P.; Dupont, H.; Riss, J.; Arditi-Djiane, J.J.; Brouqui, P. Treatment of Q fever endocarditis: Comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine. Arch. Intern. Med. 1999, 159, 167–173. [CrossRef][PubMed]
    • (1999) Arch. Intern. Med , vol.159 , pp. 167-173
    • Raoult, D.1    Houpikian, P.2    Dupont, H.3    Riss, J.4    Arditi-Djiane, J.J.5    Brouqui, P.6
  • 70
    • 0026738674 scopus 로고
    • Phagolysosomal alkalinization and the bactericidal effect of antibiotics: The Coxiella burnetii paradigm
    • [CrossRef][PubMed]
    • Maurin, M.; Benoliel, A.M.; Bongrand, P.; Raoult, D. Phagolysosomal alkalinization and the bactericidal effect of antibiotics: the Coxiella burnetii paradigm. J Infect Dis. 1992, 166, 1097–1102. [CrossRef][PubMed]
    • (1992) J Infect Dis , vol.166 , pp. 1097-1102
    • Maurin, M.1    Benoliel, A.M.2    Bongrand, P.3    Raoult, D.4
  • 71
    • 84870692452 scopus 로고    scopus 로고
    • Genome sequence of Coxiella burnetii 109, a doxycycline-resistant clinical isolate
    • [CrossRef][PubMed]
    • Rouli, L.; Rolain, J.M.; El Filali, A.; Robert, C.; Raoult, D. Genome sequence of Coxiella burnetii 109, a doxycycline-resistant clinical isolate. J. Bacteriol. 2012, 194, 6939. [CrossRef][PubMed]
    • (2012) J. Bacteriol , vol.194
    • Rouli, L.1    Rolain, J.M.2    El Filali, A.3    Robert, C.4    Raoult, D.5
  • 72
    • 0031716375 scopus 로고    scopus 로고
    • In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin. Antimicrob
    • [PubMed]
    • Gikas, A.; Spyridaki, I.; Psaroulaki, A.; Kofterithis, D.; Tselentis, Y. In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin. Antimicrob. Agents Chemother. 1998, 42, 2747–2748. [PubMed]
    • (1998) Agents Chemother , vol.42 , pp. 2747-2748
    • Gikas, A.1    Spyridaki, I.2    Psaroulaki, A.3    Kofterithis, D.4    Tselentis, Y.5
  • 73
    • 45949093972 scopus 로고    scopus 로고
    • Aerosolized antibiotics for non-cystic fibrosis bronchiectasis.
    • [CrossRef][PubMed]
    • Rubin, B.K. Aerosolized antibiotics for non-cystic fibrosis bronchiectasis. J. Aer. Med. Pulm. Drug Deliv. 2008, 21, 71–76. [CrossRef][PubMed]
    • (2008) J. Aer. Med. Pulm. Drug Deliv , vol.21 , pp. 71-76
    • Rubin, B.K.1
  • 74
    • 84960190362 scopus 로고    scopus 로고
    • In Vitro Inhibitory Activities of Liposomal Ciprofloxacin Against Lipopolysaccharide (LPS)-Induced IL-8 Release from the Calu-3 Cells
    • Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA
    • Darweesh, R.S.; Sakagami, M. In Vitro Inhibitory Activities of Liposomal Ciprofloxacin Against Lipopolysaccharide (LPS)-Induced IL-8 Release from the Calu-3 Cells. In Proceedings of Respiratory Drug Delivery 2014; Dalby, R.N., Byron, P.R., Peart, J., Suman, J.D., Farr, S.J., Young, P.M., Eds.; Davis Healthcare International Publishing: River Grove, IL, USA, 2014; pp. 747–750.
    • (2014) Proceedings of Respiratory Drug Delivery 2014 , pp. 747-750
    • Darweesh, R.S.1    Sakagami, M.2
  • 75
    • 84872120268 scopus 로고    scopus 로고
    • Safety, Tolerability, Pharmacokinetics and Antimicrobial Activity of Inhaled Liposomal Ciprofloxacin Formulations in Humans. North American Cystic Fibrosis Conference.
    • Bruinenberg, P.; Serisier, D.; Cipolla, D.; Blanchard, J. Safety, Tolerability, Pharmacokinetics and Antimicrobial Activity of Inhaled Liposomal Ciprofloxacin Formulations in Humans. North American Cystic Fibrosis Conference. Pediatr. Pulmonol. 2010, 45 (S33), 354.
    • (2010) Pediatr. Pulmonol , vol.45 , Issue.S33 , pp. 354
    • Bruinenberg, P.1    Serisier, D.2    Cipolla, D.3    Blanchard, J.4
  • 76
    • 84960190363 scopus 로고    scopus 로고
    • Safety, Tolerability and Pharmacokinetics of Novel Liposomal Ciprofloxacin Formulations for Inhalation in Healthy Volunteers and in Non-Cystic Bronchiectasis Patients
    • [CrossRef]
    • Bruinenberg, P.; Blanchard, J.; Cipolla, D.; Serisier, D. Safety, Tolerability and Pharmacokinetics of Novel Liposomal Ciprofloxacin Formulations for Inhalation in Healthy Volunteers and in Non-Cystic Bronchiectasis Patients. ATS International Conference 2010. [CrossRef]
    • (2010) ATS International Conference
    • Bruinenberg, P.1    Blanchard, J.2    Cipolla, D.3    Serisier, D.4
  • 77
    • 85026945782 scopus 로고    scopus 로고
    • Aradigm press release on 13 October 2015
    • Aradigm press release on 13 October 2015. Available online: http://investor.aradigm.com/releasedetail.cfm? ReleaseID=936283 (accessed on 18 February 2016).
  • 78
    • 79954515565 scopus 로고    scopus 로고
    • Personalized Medicine: Development of Inhalation Systems Tailored to the Individual.
    • [CrossRef][PubMed]
    • Cipolla, D.; Chan, H.-K.; Schuster, J.; Farina, D. Personalized Medicine: Development of Inhalation Systems Tailored to the Individual. Ther. Deliv. 2010, 1, 667–682. [CrossRef][PubMed]
    • (2010) Ther. Deliv , vol.1 , pp. 667-682
    • Cipolla, D.1    Chan, H.-K.2    Schuster, J.3    Farina, D.4
  • 79
    • 84901253650 scopus 로고    scopus 로고
    • Modifying the Release Properties of Liposomes toward Personalized Medicine
    • [CrossRef][PubMed]
    • Cipolla, D.; Wu, H.; Eastman, S.; Redelmeier, T.; Gonda, I.; Chan, H.-K. Modifying the Release Properties of Liposomes toward Personalized Medicine. J. Pharm. Sci. 2014, 103, 1851–1862. [CrossRef][PubMed]
    • (2014) J. Pharm. Sci , vol.103 , pp. 1851-1862
    • Cipolla, D.1    Wu, H.2    Eastman, S.3    Redelmeier, T.4    Gonda, I.5    Chan, H.-K.6
  • 81
    • 84907879111 scopus 로고    scopus 로고
    • Aerosol performance and long term stability of surfactant-associated liposomal ciprofloxacin formulations with modified encapsulation and release properties
    • [CrossRef][PubMed]
    • Cipolla, D.; Wu, H.; Gonda, I.; Chan, H.-K. Aerosol performance and long term stability of surfactant-associated liposomal ciprofloxacin formulations with modified encapsulation and release properties. AAPS PharmSciTech. 2014, 15, 1218–1227. [CrossRef][PubMed]
    • (2014) AAPS Pharmscitech , vol.15 , pp. 1218-1227
    • Cipolla, D.1    Wu, H.2    Gonda, I.3    Chan, H.-K.4
  • 82
    • 84948748207 scopus 로고    scopus 로고
    • Aerosol Performance and Stability of Liposomes Containing Ciprofloxacin Nanocrystals.
    • [CrossRef][PubMed]
    • Cipolla, D.; Wu, H.; Gonda, I.; Chan, H.-K. Aerosol Performance and Stability of Liposomes Containing Ciprofloxacin Nanocrystals. J. Aer. Med. Pulm. Drug Deliv. 2015, 28, 411–422. [CrossRef][PubMed]
    • (2015) J. Aer. Med. Pulm. Drug Deliv , vol.28 , pp. 411-422
    • Cipolla, D.1    Wu, H.2    Gonda, I.3    Chan, H.-K.4
  • 83
    • 0026785415 scopus 로고
    • Liposome Aerosols
    • [CrossRef]
    • Schreier, H. Liposome Aerosols. J. Liposome Res. 1992, 2, 145–184. [CrossRef]
    • (1992) J. Liposome Res , vol.2 , pp. 145-184
    • Schreier, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.