Xenotropic retrovirus Bxv1 in human pancreatic cell lines

Journal of Clinical Investigation

Volumn 126, Issue 3, 2016, Pages 1109-1113

  Kirkegaard, Jeannette S ^a,b   Ravassard, Philippe ^c   Ingvarsen, Signe ^a   DIedisheim, Marc ^d   Bricout Neveu, Emilie ^e   Grønborg, Mads ^a   Frogne, Thomas ^a   Scharfmann, Raphael ^d   Madsen, Ole D ^a   Rescan, Claude ^a   Albagli, Olivier ^d  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^d INSTITUT COCHIN   (France)

^e Endocells   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; B10 XENOTROPIC VIRUS 1; CONTROLLED STUDY; GOOD LABORATORY PRACTICE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; MURINE LEUKEMIA VIRUS; MUS TERRICOLOR; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SCID MOUSE; XENOTRANSPLANTATION; XENOTROPIC VIRUS; ANIMAL; CELL LINE; GENE EXPRESSION; GENETICS; METABOLISM; RAT; VIROLOGY; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; VIRUS REPLICATION; XENOGRAFT; XENOTROPIC MULV RELATED VIRUS;

VIRUS ENVELOPE PROTEIN;

ANIMALS; CELL LINE; GENE EXPRESSION; GENOME, VIRAL; HETEROGRAFTS; HUMANS; INSULIN-SECRETING CELLS; MICE; MICE, SCID; RATS; VIRAL ENVELOPE PROTEINS; VIRUS INTEGRATION; VIRUS REPLICATION; XENOTROPIC MURINE LEUKEMIA VIRUS-RELATED VIRUS;

EID: 84959925687     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI83573     Document Type: Article

References (13)

1. Ravassard P, et al. A genetically engineered human pancreatic cell line exhibiting glucose-inducible insulin secretion. J Clin Invest. 2011;121(9):3589-3597.
2. Scharfmann R, et al. Development of a conditionally immortalized human pancreatic cell line. J Clin Invest. 2014;124(5):2087-2098.
3. Hempel HA, Burns KH, De Marzo AM, Sfanos KS. Infection of Xenotransplanted Human Cell Lines by Murine Retroviruses: a lesson brought back to light by XMRV. Front Oncol. 2013;3:156.
4. Battini JL, Rasko JE, Miller AD. A human cellsurface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal transduction. Proc Natl Acad Sci U S A. 1999;96(4):1385-1390.
5. Kozak CA. The mouse xenotropic gammaretroviruses and their XPR1 receptor. Retrovirology. 2010;7:101.
6. Knouf EC, et al. Multiple integrated copies and high-level production of the human retrovirus XMRV (xenotropic murine leukemia virusrelated virus) from 22Rv1 prostate carcinoma cells. J Virol. 2009;83(14):7353-7356.
7. Sfanos KS, et al. Identification of replication competent murine gammaretroviruses in commonly used prostate cancer cell lines. PLoS One. 2011;6(6):e20874.
8. Dong B, Sullivan RH, Eugene S. A Natural human retrovirus efficiently complements vectors based on murine leukemia virus. PLoS One. 2008;3(9):e3144.
9. Metzger MJ, Holguin CJ, Mendoza R, Miller AD. The prostate cancer-associated human retrovirus XMRV lacks direct transforming activity but can induce low rates of transformation in cultured cells. J Virol. 2010;84(4):1874-1880.
10. Carlier G, et al. Human fucci pancreatic cell lines: new tools to study cell cycle and terminal differentiation. PLoS One. 2014;9(9):e108202.
11. Hughes JV, Messner K, Burnham M, Patel D, White EM. Validation of retroviral detection for rodent cell-derived products and gene therapy applications. Dev Biol Stand. 1996;88:297-304.
12. Zhang YA, et al. Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Cancer Biol Ther. 2011;12(7):617-628.
13. Hierholzer JC, Killington RA. Virus isolation and quantitation. In: Mahy BW, Kangro HI, eds. Virology Methods Manual. London, United Kingdom: Academic Press; 1996:25-46.