Effect of Roux-en-Y gastric bypass and sleeve gastrectomy on nonalcoholic fatty liver disease: A comparative study

Surgery for Obesity and Related Diseases

Volumn 12, Issue 1, 2016, Pages 127-131

  Froylich, Dvir ^a   Corcelles, Ricard ^a,b   Daigle, Christopher ^a   Boules, Mena ^a   Brethauer, Stacy ^a   Schauer, Philip ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Bariatric surgery; NAFLD; NAFLD activity score; NAS; Nonalcoholic fatty liver disease

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; AUTOIMMUNE HEPATITIS; BILIARY CIRRHOSIS; BODY MASS; CHOLANGITIS; CLINICAL ARTICLE; COHORT ANALYSIS; COMORBIDITY; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; FOLLOW UP; HEPATITIS C; HUMAN; HYPERTENSION; INTERNATIONAL NORMALIZED RATIO; INTRAOPERATIVE PERIOD; LIVER BIOPSY; LIVER FIBROSIS; LIVER HISTOLOGY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONALCOHOLIC FATTY LIVER DISEASE ACTIVITY SCORE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; ROUX EN Y GASTRIC BYPASS; ROUX Y ANASTOMOSIS; SLEEVE GASTRECTOMY; STOMACH BYPASS; SURGICAL TECHNIQUE; UNITED STATES; WEIGHT REDUCTION; COMPLICATION; GASTRECTOMY; GASTRIC BYPASS SURGERY; LAPAROSCOPY; LIVER; MORBID OBESITY; PATHOLOGY; PROCEDURES; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

BODY MASS INDEX; FEMALE; FOLLOW-UP STUDIES; GASTRECTOMY; GASTRIC BYPASS; HUMANS; LAPAROSCOPY; LIVER; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY, MORBID; POSTOPERATIVE PERIOD; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; WEIGHT LOSS;

EID: 84959542407     PISSN: 15507289     EISSN: 18787533     Source Type: Journal    
DOI: 10.1016/j.soard.2015.04.004     Document Type: Conference Paper

References (25)

1. Schauer PR, Ikramuddin S, Gourash W, Ramanathan R, Luketich J. Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity. Ann Surg 2000;232(4):515-29.
2. Clark JM, Brancati FL, Diehl AM. Nonalcoholic fatty liver disease. Gastroenterology 2002;122(6):1649-57.
3. Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastro-enterol 2003;98(5):960-7.
4. Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001;121(1):91-100.
5. Crespo J, Fernández-Gil P, Hernández-Guerra M, et al. Are there predictive factors of severe liver fibrosis in morbidly obese patients with non-alcoholic steatohepatitis? Obes Surg 2001;11(3):254-7
6. Gholam PM, Kotler DP, Flancbaum LJ. Liver pathology in morbidly obese patients undergoing roux-en-Y gastric bypass surgery. Obes Surg 2002;12(1):49-51.
7. Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hep-atology 2010;51(5):1820-32.
8. Brunt EM. Nonalcoholic steatohepatitis. Semin Liver Dis 2004;24 (1):3-20.
9. Pessayre D, Berson A, Fromenty B, Mansouri A. Mitochondria in steatohepatitis. Semin Liver Dis 2001;21(1):57-69.
10. Day CP, Saksena S. Non-alcoholic steatohepatitis: definitions and pathogenesis. J Gastroenterol Hepatol 2002;17(Suppl 3):S377-84.
11. Day CP. Pathogenesis of steatohepatitis. Best Pract Res Clin Gastro-enterol 2002;16(5):663-78.
12. Clark JM, Alkhuraishi AR, Solga SF, Alli P, Diehl AM, Magnuson TH. Roux-en-Y gastric bypass improves liver histology in patients with non-alcoholic fatty liver disease. Obes Res 2005;13(7):1180-6.
13. de Almeida SR, Rocha PR, Sanches MD, et al. Roux-en-Y gastric bypass improves the nonalcoholic steatohepatitis (NASH) of morbid obesity. Obes Surg 2006;16(3):270-8.
14. Tai CM, Huang CK, Hwang JC, et al. Improvement of nonalcoholic fatty liver disease after bariatric surgery in morbidly obese chinese patients. Obes Surg 2012;22(7):1016-21.
15. Mattar SG, Velcu LM, Rabinovitz M, et al. Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome. Ann Surg 2005;242(4):610-617; discussion 618-20.
16. Mathurin P, Hollebecque A, Arnalsteen L, et al. Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease. Gastroenterology 2009;137(2):532-40.
17. Mummadi RR, Kasturi KS, Chennareddygari S, Sood GK. Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol 2008;6 (12):1396-402.
18. Moretto M, Kupski C, da Silva VD, Padoin AV, Mottin CC. Effect of bariatric surgery on liver fibrosis. Obes Surg 2012;22(7):1044-9.
19. Shimizu H, Phuong V, Maia M, et al. Bariatric surgery in patients with liver cirrhosis. Surg Obes Relat Dis 2013;9(1):1-6.
20. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005;41(6):1313-21.
21. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94 (9):2467-74.
22. Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120(5):1183-92.
23. Wree A, Schlattjan M, Bechmann LP, et al. Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients. Metabolism 2014;63 (12):1542-52.
24. Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology 2005;42 (5):987-1000.
25. Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA. NASH Clinical Research Network (CRN). Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. Hepatology 2011;53 (3):810-20.