Effect of Short-Term Supplementation with Ready-to-Use Therapeutic Food or Micronutrients for Children after Illness for Prevention of Malnutrition: A Randomised Controlled Trial in Nigeria

PLoS Medicine

Volumn 13, Issue 2, 2016, Pages

  van der Kam, Saskia ^a,b   Salse Ubach, Nuria ^a   Roll, Stephanie ^c   Swarthout, Todd ^a   Gayton Toyoshima, Sayaka ^a   Jiya, Nma Mohammed ^d   Matsumoto, Akiko ^a   Shanks, Leslie ^a  

^a MÉDECINS SANS FRONTIÈRES   (Switzerland)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d USMANU DANFODIYO UNIVERSITY   (Nigeria)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ARTEMETHER PLUS BENFLUMETOL; TRACE ELEMENT;

ANTHROPOMETRY; ARM CIRCUMFERENCE; ARTICLE; CHILD; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOUSEHOLD; HUMAN; INCIDENCE; INFANT; LOWER RESPIRATORY TRACT INFECTION; MALARIA; MALE; MALNUTRITION; MORTALITY; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PREVALENCE; PROTOCOL COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; UGANDA; WEIGHT GAIN; CHRONIC DISEASE; DIETARY SUPPLEMENT; FORTIFIED FOOD; NIGERIA; RETROSPECTIVE STUDY; TIME FACTOR; TREATMENT OUTCOME;

CHILD, PRESCHOOL; CHRONIC DISEASE; DIETARY SUPPLEMENTS; FEMALE; FOLLOW-UP STUDIES; FOOD, FORTIFIED; HUMANS; INCIDENCE; INFANT; MALE; MALNUTRITION; MICRONUTRIENTS; NIGERIA; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 84959456839     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001952     Document Type: Article

References (41)

1. Black RE, Victora CG, Walker SP, Bhutta Z a, Christian P, de Onis M, et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet2013;382:427–51. doi: 10.1016/S0140-6736(13)60937-X23746772
2. Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet2008;371:243–60. doi: 10.1016/S0140-6736(07)61690-018207566
3. Scrimshaw NS, Tailor CE, Gordon JE, Interactions of nutrition and infection. WHO monograph series. Geneva: WHO1968; 461–472. http://libdoc.who.int/monograph/WHO_MONO_57_(part1).pdf
4. Chen LC, Chen LC, Scrimshaw NS, Interactions of diarrhea and malnutrition: mechanisms and interactions. In: Diarrhea and malnutrition: interactions, mechanisms and interventions. Plenum Publishing Corporation, New York; 1983: 3–19.
5. Tomkins A, Watson F. Malnutrition and infection—a review—Nutrition Policy Discussion Paper No.5. Geneva; 1989. http://www.unsystem.org/scn/archives/npp05/begin.htm#Contents
6. Rowland MGM, Cole TJ, Whitehead RG, A quantitative study into the role of infection in determining nutritional status in Gambian village children. Br J Nutr. 1977;37:441–450. 861194
7. Tomkins AM, Protein–energy malnutrition and risk of infection. Proceedings of the Nutrition Society. Cambridge Univ Press; 1986: 289–304. http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=677892#3099300
8. Rowland MG, Rowland SG, Cole TJ, Impact of infection on the growth of children from 0 to 2 years in an urban West African community. Am J Clin Nutr. 1988;47(1):134–138. 3337031
9. Shiff C, Checkley W, Winch P, Premij Z, Minjas J, Lubega P, Changes in weight gain and anaemia attributable to malaria in children living under holoendemic conditions. Trans R Soc Trop Med Hyg. 1996;90:262–265. 8758071
10. Guerrant RL, Lima AA, Davidson F, Micronutrients and infection: interactions and implications with enteric and other infections and future priorities. J Infect Dis. 2000;182 (Suppl 1):S134–8. 10944495
11. Friedman JF, Kurtis JD, Mtalib R, Opollo M, Lanar DE, Duffy PE, Malaria is related to decreased nutritional status among male adolescents and adults in the setting of intense perennial transmission. J Infect Dis. 2003;188(3):449–57. 12870128
12. Hoare S, Poppitt SD, Prentice AM, Weaver LT, Dietary supplementation and rapid catch-up growth after acute diarrhoea in childhood. Br J Nutr. 1996;76(4):479–90. 8942357
13. Scrimshaw NS, Sangiovanni JC, Synergism of nutrition, infection, and immunity: an overview. Am J Clin Nutr. 1997;66 (Suppl): S464–77.
14. Pnasziou P, Meackerras DE, Vitamin A supplementation in infectious diseases : a meta-analysis. BMJ. 1993;306:197–201.
15. Mahalanabis D, Bhan MK, Micronutrients as adjunct therapy of acute illness in children : impact on the episode outcome and policy implications of current findings. Br J Nut. 2001;85(Suppl 2):S151–8.
16. Scrimshaw NS, Historical concepts of interactions, synergism and antagonism between nutrition and infection. J Nutr. 2003;133(1)(Suppl):S316–21.
17. Aggarwal R, Sentz J, Miller MA, Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: a meta-analysis. Pediatrics. 2007;119(6):1120–30. 17545379
18. Sharieff W, Bhutta Z, Schauer C, Tomlinson G, Zlotkin S, Micronutrients (including zinc) reduce diarrhoea in children: the Pakistan Sprinkles Diarrhoea Study. Arch Dis Child. 2006;91(7):573–9. 16556612
19. Soofi S, Cousens S, Iqbal SP, Akhund T, Khan J, Ahmed I, et al. Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: a cluster-randomised trial. Lancet. 2013;382:29–40. doi: 10.1016/S0140-6736(13)60437-723602230
20. Ramakrishnan U, Aburto N, Mccabe G, Martorell R, Multimicronutrient interventions but not vitamin A or iron interventions alone improve child growth: results of 3 meta-analyses. J Nutr. 2004;134:2592–602. 15465753
21. Bhutta ZA, Das JK, Rizvi A, Gaffey MF, Walker N, Horton S, et al. Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost?Lancet2013;382:452–77. doi: 10.1016/S0140-6736(13)60996-423746776
22. Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, et al. Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. JAMA2009;301(3):277. doi: 10.1001/jama.2008.101819155454
23. Hess SY, Abbeddou S, Jimenez EY, Somé JW, Vosti SA, Ouédraogo ZP, et al. Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young burkinabe children: a cluster-randomized trial. PLoS ONE. 2015;10(3):e0122242. doi: 10.1371/journal.pone.012224225816354
24. Huybregts L, Houngbé F, Salpéteur C, Brown R, Roberfroid D, Ait-Aissa M, et al. The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster-randomized controlled Trial. PLoS Med. 2012;9(9):e1001313. doi: 10.1371/journal.pmed.100131323028263
25. Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D, Gaboulaud V, et al. Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. JAMA. 2009;301(3):277–85. doi: 10.1001/jama.2008.101819155454
26. WHOFood, water and family health: A manual for community educators. Geneva: WHO, UNDP; 1994;p19,27. http://apps.who.int/iris/bitstream/10665/62963/1/WHO_HEP_94.2.pdf?ua=1
27. Dewey KG. Guiding principles for complementary feeding of the breastfed child. WHO; 2003; p.26. http://whqlibdoc.who.int/paho/2003/a85622.pdf?ua=1
28. Dewey KG. Guiding principles for feeding non-breastfed children 6–24 months of age. WHO; 2005; p.23. http://apps.who.int/iris/bitstream/10665/43281/1/9241593431.pdf?ua=1&ua=1
29. van der Kam S, Swarthout T, Niragira O, Froud A, Sompwe ME, Mills C, et al. Ready-to-use therapeutic food for catch-up growth in children after an episode of Plasmodium falciparum malaria: an open randomised controlled trial. PLoS ONE. 2012;7(4): e35006. doi: 10.1371/journal.pone.003500622558108
30. van der Kam S, Roll S, Swarthout T, Edyegu-Otelu G, Matsumoto A, Kasujja FX, et al. Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after Illness for prevention of malnutrition: a randomised controlled trial in Uganda. PLoS Med. 2016;13(1):e1001951.
31. FEWSNET. Preliminary livelihoods zoning: Northern Nigeria. 2007; p.18. http://www.fews.net/sites/default/files/documents/reports/ng_zonedescriptions_en.pdf
32. Theuri T. Goronyo Underlying causes of Malnutrition. 2009.
33. Baily J. Nutrition survey March 2009, Goronyo, Sokoto state, Nigeria. 2009.
34. MSF-OCA. Nutrition Survey Results March 2010 Goronyo, Sokoto state, Nigeria. 2010.
35. SCF. Child malnutrition in Northern Nigeria: an illustrative case study. 2012. http://www.heawebsite.org/download/file/fid/373
36. WHO; WFP; UNICEF. Preventing and controlling micronutrient deficiencies in populations affected by an emergency. 2007. http://www.who.int/nutrition/publications/WHO_WFP_UNICEFstatement.pdf
37. Prentice AM, Iron metabolism, malaria and other infections: what is all the fuss about ?J Nutr. 2008;138:2537–2541. doi: 10.3945/jn.108.09880619022986
38. Veenemans J, Milligan P, Prentice AM, Schouten LRA, Inja N, van der Heijden AC, et al. Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: a randomised trial. PLoS Med. 2011;8(11):e1001125.
39. Ojukwu JU, Okebe JU, Yahav D, Paul M, Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas (Review). Cochrane Database Syst Rev. 2009;(4).
40. Okebe J, Yahav D, Shbita R, Paul M, Oral iron supplements for children in malaria-endemic areas. Cochrane Database Syst Rev. 2011;(10).
41. Abbeddou S, Hess SY, Jimenez EY, Somé JW, Vosti SA, Guissou RM, et al. Comparison of methods to assess adherence to small-quantity lipid-based nutrient supplements (SQ-LNS) and dispersible tablets among young Burkinabe children participating in a community-based intervention trial. Matern Child Nutr. 2014;1–30.