Long-term shedding of influenza virus, parainfluenza virus, respiratory syncytial virus and nosocomial epidemiology in patients with hematological disorders

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Lehners, Nicola ^a   Tabatabai, Julia ^a   Prifert, Christiane ^b   Wedde, Marianne ^c   Puthenparambil, Joe ^a   Weissbrich, Benedikt ^b   Biere, Barbara ^c   Schweiger, Brunhilde ^c   Egerer, Gerlinde ^a   Schnitzler, Paul ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HEMATOLOGIC DISEASE; HOSPITAL INFECTION; HUMAN; HUMAN PARAINFLUENZA VIRUS 3; HUMAN RESPIRATORY SYNCYTIAL VIRUS; HUMAN RESPIRATORY SYNCYTIAL VIRUS A; IMMUNOCOMPROMIZED PATIENT; INFECTION CONTROL; INFLUENZA; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); INFLUENZA B VIRUS; INFLUENZA VIRUS; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORTALITY; NUCLEOTIDE SEQUENCE; PARAINFLUENZA VIRUS INFECTION; PARAMYXOVIRINAE; PHYLOGENY; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT DISEASE; RETROSPECTIVE STUDY; THROAT CULTURE; VIRAL CLEARANCE; VIRUS DETECTION; VIRUS SHEDDING; VIRUS TRANSMISSION; ALLOTRANSPLANTATION; COHORT ANALYSIS; COMMUNICABLE DISEASE CONTROL; CROSS INFECTION; DNA SEQUENCE; METABOLISM; MIDDLE AGED; MUTATION; NOSE; ORTHOMYXOVIRIDAE; PARAMYXOVIRUS INFECTION; POLYMERASE CHAIN REACTION; TIME FACTOR; VERY ELDERLY; VIROLOGY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; COMMUNICABLE DISEASE CONTROL; CROSS INFECTION; FEMALE; GENOTYPE; HEMATOLOGIC DISEASES; HUMANS; INFLUENZA, HUMAN; MALE; MIDDLE AGED; MUTATION; NOSE; ORTHOMYXOVIRIDAE; PARAINFLUENZA VIRUS 3, HUMAN; PARAMYXOVIRIDAE INFECTIONS; PHYLOGENY; POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS; VIRUS SHEDDING; YOUNG ADULT;

EID: 84959432774     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148258     Document Type: Article

References (48)

1. Avetisyan G, Mattsson J, Sparrelid E, Ljungman P. Respiratory syncytial virus infection in recipients of allogeneic stem-cell transplantation: a retrospective study of the incidence, clinical features, and outcome. Transplantation 2009; 88: 1222-1226. PMID: 19935377
2. Chemaly RF, Ghosh S, Bodey GP, Rohatgi N, Safdar A, Keating MJ, et al. Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: a retrospective study at a major cancer center. Medicine (Baltimore) 2006; 85: 278-287.
3. Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med 2005; 352: 1749-1759. PMID: 15858184
4. Renaud C, Xie H, Seo S, Kuypers J, Cent A, Corey L, et al. Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients. Biol Blood Marrow Transplant 2013; 19: 1220-1226. doi: 10.1016/j.bbmt.2013.05.005 PMID: 23680472
5. du Prel JB, Puppe W, Gröndahl B, Knuf M, Weigl JAI, et al. Are meteorological parameters associated with acute respiratory tract infections? Clin Infect Dis 2009; 49: 861-868. doi: 10.1086/605435 PMID: 19663691
6. Englund JA, Karron RA, Cunningham CK, Larussa P, Melvin A, Yogev R, et al. Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children. Vaccine 2013; 31: 5706-5712. doi: 10.1016/j. vaccine.2013.09.046 PMID: 24103895
7. Nichols WG, Guthrie KA, Corey L, Boeckh M. Influenza infections after hematopoietic stem cell transplantation; risk factors, mortality, and the effect of antiviral therapy. Clin Infect Dis 2004; 39: 1300-1306. PMID: 15494906
8. Whimbey E, Champlin RE, Couch RB, Englund JA, Goodrich JM, Raad I, et al. Community respiratory virus infections among hospitalized adult bone marrow transplant recipients. Clin Infect Dis 1996; 22: 778-782. PMID: 8722930
9. Lehners N, Geis S, Eisenbach C, Neben K, Schnitzler P. Changes in severity of influenza A(H1N1) pdm09 infection from pandemic to first postpandemic season, Germany. Emerg Infect Dis 2013; 19: 748-755. doi: 10.3201/eid1905.130034 PMID: 23697801
10. Hirsch H, Boeckh M, Einsele H, Martino R, Ward KN (2012) Community-acquired respiratory virus (CARV) infections other than influenza and adenovirus: Respiratory syncytial-, human metapneumo-, parainfluenza-, rhino-, and coronavirus, 4th European Conference on Infections in Leukemia, Juan-les-Pins, France. 2012. Available: http://www.leukemia-net.org/content/treat-research/supportive-care/standards-sop-and-recommendations/index-eng.html.
11. Tomblyn M, Chiller T, Einsele H, Gress R, Sepkowitz K, Storek J, et al. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant 2009; 15: 1143-1238. doi: 10.1016/j.bbmt.2009.06.019 PMID: 19747629
12. Karron RA, Buchholz UJ, Collins PL. Live-attenuated respiratory syncytial virus vaccines. Curr Top Microbiol Immunol 2013; 372: 259-284. doi: 10.1007/978-3-642-38919-1-13 PMID: 24362694
13. Mazzulli T, Peret TC, McGeer A, Cann D, MacDonald KS, Chua R, et al. Molecular characterization of a nosocomial outbreak of human respiratory syncytial virus on an adult leukemia/lymphoma ward. J Infect Dis 1999; 180: 1686-1689. PMID: 10515833
14. Garcia O, Martin M, Dopazo J, Arbiza J, Frabasile S, Russi J, et al. Evolutionary pattern of human respiratory syncytial virus (subgroup A): cocirculating lineages and correlation of genetic and antigenic changes in the G glycoprotein. J Virol 1994; 68: 5448-5459. PMID: 8057427
15. Hayden FG. Prevention and treatment of influenza in immunocompromised patients. Am J Med 1997; 102: 55-60. PMID: 10868144
16. Falcone V, Bierbaum S, Kern W, Kontny U, Bertz H, Huzly D, et al. Influenza virus A(H1N1)pdm09 hemagglutinin polymorphism and associated disease in southern Germany during the 2010/11 influenza season. Arch Virol 2013; 158: 1297-1303. doi: 10.1007/s00705-013-1610-1 PMID: 23397331
17. Geis S, Prifert C, Weissbrich B, Lehners N, Egerer G, Eisenbach C, et al. Molecular characterization of a respiratory syncytial virus (RSV) outbreak in a hematology unit, Heidelberg, Germany. J Clin Microbiol 2013; 51: 155-162. doi: 10.1128/JCM.02151-12 PMID: 23100345
18. Lehners N, Schnitzler P, Geis S, Puthenparambil J, Benz MA, Alber B, et al. Risk factors and containment of a respiratory syncytial virus outbreak in a hematology and transplant unit. Bone Marrow Transplant 2013;1-6, doi: 10.1038/bmt.2013.94
19. Milano F, Campbell AP, Guthrie KA, Kuypers J, Englund JA, Corey L, et al. Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients. Blood 2010; 115: 2088-2094. doi: 10.1182/blood-2009-09-244152 PMID: 20042728
20. Peret TC, Hall CB, Schnabel KC, Golub JA, Anderson LJ. Circulation patterns of genetically distinct group A and B strains of human respiratory syncytial virus in a community. J Gen Virol 1998; 79: 2221-2229. PMID: 9747732
21. Tamura K, Nei M. Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol 1993; 10: 512-526. PMID: 8336541
22. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011; 28: 2731-2739. doi: 10.1093/molbev/msr121 PMID: 21546353
23. Nichols WG, Corey L, Gooley T, Davis C, Boeckh M. Parainfluenza virus infections after hematopoietic stem cell transplantation: risk factors, response to antiviral therapy, and effect on transplant outcome. Blood 2001; 98: 573-578. PMID: 11468152
24. Mayer JL, Lehners N, Egerer G, Kauczor HU, Heußel CP. (2014) CT-morphological characterization of respiratory syncytial virus (RSV) pneumonia in immune-compromised adults. Fortschr Röntgenstr 2014. doi: 10.1055/s-0033-1356353
25. McCarthy AJ, Kingman HM, Kelly C, Taylor GS, Caul EO, Grier D, et al. The outcome of 26 patients with respiratory syncytial virus infection following allogeneic stem cell transplantation. Bone marrow transplant 1999; 24: 1315-1322. PMID: 10627641
26. Torres HA, Aguilera EA, Mattiuzzi GN, Cabanillas ME, Rohatgi N, Sepulveda CA, et al. Characteristics and outcome of respiratory syncytial virus infection in patients with leukemia. Haematologica 2007; 92: 1216-1223. PMID: 17666367
27. Buda S, Schweiger B, Buchholz U, Köpke K, Prahm K, Haas W, et al. Influenza weekly report. Kalenderwoche 15 (06.04. bis 12.04.2013). Arbeitsgemeinschaft Influenza Robert Koch-Institut, Berlin. 2013: Available: http://influenza.rki.de/Wochenberichte/2012-2013/2013-15.pdf.
28. European Centre for Disease Prevention and Control. Influenza virus characterization. Summary Europe, March 2013 Pandemic influenza A(H1N1) virus mutations reported to be associated with severe disease. 2013. Available: http://www.ecdc.europa.eu/en/publications/Publications/influenzavirus-characterisation-mar-2013.pdf.
29. Grund S, Roggendorf M, Schweiger B. Outbreak of influenza virus A/H1N1 in a hospital ward for immunocompromised patients. Arch Virol 2010; 155: 1797-1802. doi: 10.1007/s00705-010-0771-4 PMID: 20697920
30. Pollara CP, Piccinelli G, Rossi G, Cattaneo C, Perandin F, Corbellini S, et al. Nosocomial outbreak of the pandemic Influenza A (H1N1) 2009 in critical hematologic patients during seasonal influenza 2010-2011: detection of oseltamivir resistant variant viruses. BMC Infect Dis 2013; 13: 127. doi: 10.1186/1471-2334-13-127 PMID: 23496867
31. Trento A, Galiano M, Videla C, Carballal G, Garcia-Barreno B, Melero JA, et al. Major changes in the G protein of human respiratory syncytial virus isolates introduced by a duplication of 60 nucleotides. J Gen Virol 2003; 84: 3115-3120. PMID: 14573817
32. Cane PA, Pringle CR. Evolution of subgroup A respiratory syncytial virus: evidence for progressive accumulation of amino acid changes in the attachment protein. J Virol 1995; 69: 2918-2925. PMID: 7707517
33. Reiche J, Schweiger B. Genetic variability of group A human respiratory syncytial virus strains circulating in Germany from 1998 to 2007. J Clin Microbiol 2009; 47: 1800-1810. doi: 10.1128/JCM.02286-08 PMID: 19386848
34. Eshaghi A, Duvvuri VR, Lai R, Nadarajah JT, Li A, Patel SN, et al. Genetic variability of human respiratory syncytial virus A strains circulating in Ontario: a novel genotype with a 72 nucleotide G gene duplication. PLoS ONE. 2012; 7: e32807. doi: 10.1371/journal.pone.0032807 PMID: 22470426
35. Prifert C, Streng A, Krempl CD, Liese J, Weissbrich B. Novel respiratory syncytial virus a genotype, Germany, 2011-2012. Emerg Infect Dis 2013; 19: 1029-1030. doi: 10.3201/eid1906.121582 PMID: 23735287
36. Panayiotou C, Richter J, Koliou M, Kalogirou N, Georgiou E, Christodoulou C. Epidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity. Epidemiol Infect 2014; 24: 1-6.
37. Trento A, Casas I, Calderón A, Garcia-Garcia ML, Calvo C, Perez-Breña P, et al. Ten years of global evolution of the human respiratory syncytial virus BA genotype with a 60-nucleotide duplication in the G protein gene. J Virol 2010; 84: 7500-7512. doi: 10.1128/JVI.00345-10 PMID: 20504933
38. Tabatabai J, Prifert C, Pfeil J, Grulich-Henn J, Schnitzler P. Novel respiratory syncytial virus (RSV) genotype ON1 predominates in Germany during winter season 2012-13. PLoS ONE 2014; 9: e109191. doi: 10.1371/journal.pone.0109191 PMID: 25290155
39. Pretorius MA, van Niekerk S, Tempia S, Moyes J, Cohen C, Madhi SA, et al. Replacement and positive evolution of subtype A and B respiratory syncytial virus G-protein genotypes from 1997-2012 in South Africa. J Infect Dis 2013; 208: S227-S237. PMID: 24265482
40. Abdallah A, Rowland KE, Schepetiuk SK, To LB, Bardy P. An outbreak of respiratory syncytial virus infection in a bone marrow transplant unit: effect on engraftment and outcome of pneumonia without specific antiviral treatment. Bone Marrow Transplant 2003; 32: 195-203. PMID: 12838285
41. Lavergne V, Ghannoum M, Weiss K, Roy J, Béliveau C. Successful prevention of respiratory syncytial virus nosocomial transmission following an enhanced seasonal infection control program. Bone Marrow Transplant 2011; 46: 137-142. doi: 10.1038/bmt.2010.67 PMID: 20383207
42. Lessler J, Reich NG, Brookmeyer R, Perl TM, Nelson KE, Cummings DA. Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect Dis 2009; 9: 291-300. doi: 10.1016/S1473-3099(09)70069-6 PMID: 19393959
43. Khanna N, Widmer AF, Decker M, Steffen I, Halter J, Heim D, et al. Respiratory syncytial virus infection in patients with hematological diseases: single-center study and review of the literature. Clin Infect Dis 2008; 46: 402-412. doi: 10.1086/525263 PMID: 18181739
44. Jalal H, Bibby DF, Bennett J, Sampson RE, Brink NS, MacKinnon S, et al. Molecular investigations of an outbreak of parainfluenza virus type 3 and respiratory syncytial virus infections in a hematology unit. J Clin Microbiol 2007; 45: 1690-1696. PMID: 17392447
45. Taylor GS, Vipond IB, Caul EO. Molecular epidemiology of outbreak of respiratory syncytial virus within bone marrow transplantation unit. J Clin Microbiol 2001; 39: 801-803. PMID: 11158157
46. Ljungman P, Cordonnier C, Einsele H, Englund J, Machado CM, Storek J, et al. Vaccination of hematopoietic cell transplant recipients. Bone Marrow Transplant 2009; 44: 521-526. doi: 10.1038/bmt.2009. 263 PMID: 19861986
47. Luchsinger V, Piedra PA, Ruiz M, Zunino E, Martinez MA, Machado C, et al. Role of neutralizing antibodies in adults with community-acquired pneumonia by respiratory syncytial virus. Clin Infect Dis 2012; 54: 905-912. doi: 10.1093/cid/cir955 PMID: 22238168
48. De Vincenzo JP. The promise, pitfalls and progress of RNA-interference-based antiviral therapy for respiratory viruses. Antivir Ther 2012; 17: 213-225. doi: 10.3851/IMP2064 PMID: 22311654