GDF-15 is elevated in children with mitochondrial diseases and is induced by mitochondrial dysfunction

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Montero, Raquel ^a,b,c,h   Yubero, Delia ^a,b,c,h   Villarroya, Joan ^c,d   Henares, Desiree ^a   Jou, Cristina ^a,b,c,h   Rodríguez, Maria Angeles ^a,c   Ramos, Federico ^a   Nascimento, Andrés ^a,b,c,h   Ortez, Carlos Ignacio ^a,c   Campistol, Jaume ^a,b,c,h   Perez Dueñas, Belen ^a,b,c,h   O'Callaghan, Mar ^a,c   Pineda, Mercedes ^b,c,h   Garcia Cazorla, Angeles ^a,b,c,h   Oferil, Jaume Colomer ^a   Montoya, Julio ^b,e,h   Ruiz Pesini, Eduardo ^b,e,h   Emperador, Sonia ^b,e,h   Meznaric, Marija ^f   Campderros, Laura ^c,d   Kalko, Susana G ^g   Villarroya, Francesc ^c,d   Artuch, Rafael ^a,b,c,h   Jimenez Mallebrera, Cecilia ^a,b,c,h   more..

^a HOSPITAL SANT JOAN DE DÉU   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^c Sant Joan de Deu   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

^e UNIVERSITY OF ZARAGOZA   (Spain)

^f UNIVERSITY OF LJUBLJANA   (Slovenia)

^g HOSPITAL CLÍNIC   (Spain)

^h INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIMYCIN A1; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR 21; GROWTH DIFFERENTIATION FACTOR 15; OLIGOMYCIN; FIBROBLAST GROWTH FACTOR; GDF15 PROTEIN, HUMAN; MESSENGER RNA;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FGF21 GENE; GDF15 GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MITOCHONDRIAL ENCEPHALOMYOPATHY; MOUSE; MYOTUBE; NONHUMAN; PREDICTIVE VALUE; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; ANIMAL; BLOOD; CASE CONTROL STUDY; CELL LINE; COHORT ANALYSIS; FEMALE; INFANT; MALE; METABOLISM; MYOBLAST; NEUROMUSCULAR DISEASE; PRESCHOOL CHILD; REPRODUCIBILITY; SKELETAL MUSCLE; SKELETAL MUSCLE CELL;

ADOLESCENT; ANIMALS; BIOMARKERS; CASE-CONTROL STUDIES; CELL LINE; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; FIBROBLAST GROWTH FACTORS; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; INFANT; MALE; MICE; MITOCHONDRIAL DISEASES; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MYOBLASTS; NEUROMUSCULAR DISEASES; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 84959431929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148709     Document Type: Article

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