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Volumn 11, Issue 2, 2016, Pages

A simple test of class-level genetic association can reveal novel cardiometabolic trait loci

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARDIOMETABOLIC TRAIT LOCUS; COMPUTER PROGRAM; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC CLASS ASSOCIATION TESTING; GENETIC SCREENING; HUMAN; QUANTITATIVE TRAIT LOCUS; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STANDARDIZATION; STATISTICAL ANALYSIS; CARDIAC MUSCLE; GENE LOCUS; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; META ANALYSIS (TOPIC); METABOLIC DISORDER; METABOLISM; PHENOTYPE;

EID: 84959423145     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148218     Document Type: Article
Times cited : (6)

References (32)
  • 1
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • 20686565 Aug
    • Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug; 466:707-713. doi: 10.1038/ nature09270 PMID: 20686565
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3    Edmondson, A.C.4    Stylianou, I.M.5    Koseki, M.6
  • 2
    • 84887099827 scopus 로고    scopus 로고
    • Discovery and refinement of loci associated with lipid levels
    • 24097068 Nov
    • Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafson S, Kanoni S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013 Nov; 45(11):1274-1283. doi: 10.1038/ng. 2797 PMID: 24097068
    • (2013) Nat Genet. , vol.45 , Issue.11 , pp. 1274-1283
    • Willer, C.J.1    Schmidt, E.M.2    Sengupta, S.3    Peloso, G.M.4    Gustafson, S.5    Kanoni, S.6
  • 3
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • 21378990 Apr
    • Schunkert H, Konig IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Apr; 43 (4):333-338. doi: 10.1038/ng.784 PMID: 21378990
    • (2011) Nat Genet. , vol.43 , Issue.4 , pp. 333-338
    • Schunkert, H.1    Konig, I.R.2    Kathiresan, S.3    Reilly, M.P.4    Assimes, T.L.5    Holm, H.6
  • 4
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • 23202125 Jan
    • Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013 Jan; 45(1):25-33. doi: 10.1038/ng.2480 PMID: 23202125
    • (2013) Nat Genet. , vol.45 , Issue.1 , pp. 25-33
    • Deloukas, P.1    Kanoni, S.2    Willenborg, C.3    Farrall, M.4    Assimes, T.L.5    Thompson, J.R.6
  • 5
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • 20581827 Jul
    • Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010 Jul; 42(7):579-589. doi: 10.1038/ng.609 PMID: 20581827
    • (2010) Nat Genet. , vol.42 , Issue.7 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3    Morris, A.P.4    Dina, C.5    Welch, R.P.6
  • 6
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • 22885922 Sep
    • Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012 Sep; 44(9):981-990. doi: 10.1038/ng.2383 PMID: 22885922
    • (2012) Nat Genet. , vol.44 , Issue.9 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3    Ferreira, T.4    Segre, A.V.5    Steinthorsdottir, V.6
  • 7
    • 78049337953 scopus 로고    scopus 로고
    • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    • 20935630 Nov
    • Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42 (11):937-948. doi: 10.1038/ng.686 PMID: 20935630
    • (2010) Nat Genet. , vol.42 , Issue.11 , pp. 937-948
    • Speliotes, E.K.1    Willer, C.J.2    Berndt, S.I.3    Monda, K.L.4    Thorleifsson, G.5    Jackson, A.U.6
  • 8
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • 20881960 Oct
    • Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct; 467 (7317):832-838. doi: 10.1038/nature09410 PMID: 20881960
    • (2010) Nature , vol.467 , Issue.7317 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3    Berndt, S.I.4    Weedon, M.N.5    Rivadeneira, F.6
  • 9
    • 78049349396 scopus 로고    scopus 로고
    • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
    • 20935629 Nov
    • Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010 Nov; 42(11):949-960. doi: 10.1038/ng.685 PMID: 20935629
    • (2010) Nat Genet. , vol.42 , Issue.11 , pp. 949-960
    • Heid, I.M.1    Jackson, A.U.2    Randall, J.C.3    Winkler, T.W.4    Qi, L.5    Steinthorsdottir, V.6
  • 10
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • 20081858 Feb
    • Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010 Feb; 42(2):105-116. doi: 10.1038/ng.520 PMID: 20081858
    • (2010) Nat Genet. , vol.42 , Issue.2 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3    Saxena, R.4    Soranzo, N.5    Jackson, A.U.6
  • 11
    • 78649461131 scopus 로고    scopus 로고
    • Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways
    • 20858683 Dec
    • Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, et al. Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways. Diabetes. 2010 Dec; 59 (12):3229-3239. doi: 10.2337/db10-0502 PMID: 20858683
    • (2010) Diabetes. , vol.59 , Issue.12 , pp. 3229-3239
    • Soranzo, N.1    Sanna, S.2    Wheeler, E.3    Gieger, C.4    Radke, D.5    Dupuis, J.6
  • 12
    • 77955981355 scopus 로고    scopus 로고
    • Genome-wide gene and pathway analysis
    • 20442747 Sep
    • Luo L, Peng G, Zhu Y, Dong H, Amos CI, Xiong M. Genome-wide gene and pathway analysis. Eur J Hum Genet. 2010 Sep; 18(9):1045-1053. doi: 10.1038/ejhg.2010.62 PMID: 20442747
    • (2010) Eur J Hum Genet. , vol.18 , Issue.9 , pp. 1045-1053
    • Luo, L.1    Peng, G.2    Zhu, Y.3    Dong, H.4    Amos, C.I.5    Xiong, M.6
  • 13
    • 77955064853 scopus 로고    scopus 로고
    • A versatile gene-based test for genome-wide association studies
    • 20598278 Jul
    • Liu JZ, McRae AF, Nyholt DR, Medland SE, Wray NR, Brown KM, et al. A versatile gene-based test for genome-wide association studies. Am J Hum Genet. 2010 Jul; 87(1):139-145. doi: 10.1016/j.ajhg. 2010.06.009 PMID: 20598278
    • (2010) Am J Hum Genet. , vol.87 , Issue.1 , pp. 139-145
    • Liu, J.Z.1    McRae, A.F.2    Nyholt, D.R.3    Medland, S.E.4    Wray, N.R.5    Brown, K.M.6
  • 14
    • 0034781050 scopus 로고    scopus 로고
    • A simple correction for multiple comparisons in interval mapping genome scans
    • Cheverud JM. A simple correction for multiple comparisons in interval mapping genome scans. Heredity. 2001; 87: 5 2-58. doi: 10.1046/j.1365-2540.2001.00901.x
    • (2001) Heredity. , vol.87 , pp. 52-58
    • Cheverud, J.M.1
  • 15
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • 14997420
    • Nyholt DR. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. American Journal of Human Genetics. 2004; 74:765-769. doi: 10.1086/ 383251 PMID: 14997420
    • (2004) American Journal of Human Genetics. , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 16
    • 79952467494 scopus 로고    scopus 로고
    • GATES: A rapid and powerful gene-based association test using extended Simes procedure
    • Mar
    • LiMX, Gui HS, Kwan JS, Sham PC. GATES: a rapid and powerful gene-based association test using extended Simes procedure. Am J HumGenet. 2011 Mar; 88(3):283-293. doi: 10.1016/j.ajhg.2011.01.019
    • (2011) Am J HumGenet. , vol.88 , Issue.3 , pp. 283-293
    • Li, M.X.1    Gui, H.S.2    Kwan, J.S.3    Sham, P.C.4
  • 17
    • 77953121307 scopus 로고    scopus 로고
    • Powerful SNP-set analysis for case-control genome-wide association studies
    • 20560208 Jun
    • Wu MC, Kraft P, Epstein MP, Taylor DM, Chanock SJ, Hunter DJ, et al. Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet. 2010 Jun; 86(6):929-942. doi: 10.1016/j.ajhg.2010.05.002 PMID: 20560208
    • (2010) Am J Hum Genet. , vol.86 , Issue.6 , pp. 929-942
    • Wu, M.C.1    Kraft, P.2    Epstein, M.P.3    Taylor, D.M.4    Chanock, S.J.5    Hunter, D.J.6
  • 18
    • 84856052210 scopus 로고    scopus 로고
    • Gene-based tests of association
    • 21829371 Jul
    • Huang H, Chanda P, Alonso A, Bader JS, Arking DE. Gene-based tests of association. PLoS Genet. 2011 Jul; 7(7):e1002177. doi: 10.1371/journal.pgen.1002177 PMID: 21829371
    • (2011) PLoS Genet. , vol.7 , Issue.7
    • Huang, H.1    Chanda, P.2    Alonso, A.3    Bader, J.S.4    Arking, D.E.5
  • 19
    • 50949095168 scopus 로고    scopus 로고
    • Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
    • 18691683 Sep
    • Li B, Leal SM. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet. 2008 Sep; 83(3):311-321. doi: 10.1016/j.ajhg.2008. 06.024 PMID: 18691683
    • (2008) Am J Hum Genet. , vol.83 , Issue.3 , pp. 311-321
    • Li, B.1    Leal, S.M.2
  • 20
    • 84881660693 scopus 로고    scopus 로고
    • Meta-analysis of gene-level associations for rare variants based on single-variant statistics
    • Aug
    • Hu YJ, Berndt SI, Gustafsson S, Ganna A, Hirschhorn J, North KE, et al. Meta-analysis of gene-level associations for rare variants based on single-variant statistics. Am J Hum Genet. 2013 Aug; 93 (2):236-248. doi: 10.1016/j.ajhg.2013.06.011
    • (2013) Am J Hum Genet. , vol.93 , Issue.2 , pp. 236-248
    • Hu, Y.J.1    Berndt, S.I.2    Gustafsson, S.3    Ganna, A.4    Hirschhorn, J.5    North, K.E.6
  • 21
    • 84895808047 scopus 로고    scopus 로고
    • Meta-analysis of gene-level tests for rare variant association
    • 24336170 Feb
    • Liu DJ, Peloso GM, Zhan X, Holmen OL, Zawistowski M, Feng S, et al. Meta-analysis of gene-level tests for rare variant association. Nat Genet. 2014 Feb; 46(2):200-204. doi: 10.1038/ng.2852 PMID: 24336170
    • (2014) Nat Genet. , vol.46 , Issue.2 , pp. 200-204
    • Liu, D.J.1    Peloso, G.M.2    Zhan, X.3    Holmen, O.L.4    Zawistowski, M.5    Feng, S.6
  • 22
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • 12808457 Jul
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003 Jul; 34(3):267-273. doi: 10.1038/ng1180 PMID: 12808457
    • (2003) Nat Genet. , vol.34 , Issue.3 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3    Subramanian, A.4    Sihag, S.5    Lehar, J.6
  • 23
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • 16199517 Oct
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005 Oct; 102:15545-15550. doi: 10.1073/pnas.0506580102 PMID: 16199517
    • (2005) Proc Natl Acad Sci USA. , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 24
    • 77449140764 scopus 로고    scopus 로고
    • Gene and pathway-based second-wave analysis of genome-wide association studies
    • 19584899 Jan
    • Peng G, Luo L, Siu H, Zhu Y, Hu P, Hong S, et al. Gene and pathway-based second-wave analysis of genome-wide association studies. Eur J Hum Genet. 2010 Jan; 18(1):111-117. doi: 10.1038/ejhg. 2009.115 PMID: 19584899
    • (2010) Eur J Hum Genet. , vol.18 , Issue.1 , pp. 111-117
    • Peng, G.1    Luo, L.2    Siu, H.3    Zhu, Y.4    Hu, P.5    Hong, S.6
  • 25
    • 77957342306 scopus 로고    scopus 로고
    • Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
    • Aug
    • Segre AV, Groop L, Mootha VK, Daly MJ, Altshuler D. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 2010 Aug; 6. doi: 10.1371/journal.pgen.1001058
    • (2010) PLoS Genet. , vol.6
    • Segre, A.V.1    Groop, L.2    Mootha, V.K.3    Daly, M.J.4    Altshuler, D.5
  • 26
    • 79955121427 scopus 로고    scopus 로고
    • SNP-based pathway enrichment analysis for genome-wide association studies
    • 21496265
    • Weng L, Macciardi F, Subramanian A, Guffanti G, Potkin SG, Yu Z, et al. SNP-based pathway enrichment analysis for genome-wide association studies. BMC Bioinformatics. 2011; 12:99. doi: 10.1186/ 1471-2105-12-99 PMID: 21496265
    • (2011) BMC Bioinformatics. , vol.12 , pp. 99
    • Weng, L.1    Macciardi, F.2    Subramanian, A.3    Guffanti, G.4    Potkin, S.G.5    Yu, Z.6
  • 27
    • 84873562917 scopus 로고    scopus 로고
    • Mixed modeling of meta-analysis Pvalues (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol
    • 23405096
    • Foulkes AS, Matthews GJ, Das U, Ferguson JF, Lin R, Reilly MP. Mixed modeling of meta-analysis Pvalues (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol. PLoS ONE. 2013; 8(2):e54812. doi: 10.1371/journal.pone.0054812 PMID: 23405096
    • (2013) PLoS ONE. , vol.8 , Issue.2
    • Foulkes, A.S.1    Matthews, G.J.2    Das, U.3    Ferguson, J.F.4    Lin, R.5    Reilly, M.P.6
  • 28
    • 80051499915 scopus 로고    scopus 로고
    • Rare-variant association testing for sequencing data with the sequence kernel association test
    • 21737059 Jul
    • Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X. Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet. 2011 Jul; 89(1):82-93. doi: 10.1016/j.ajhg. 2011.05.029 PMID: 21737059
    • (2011) Am J Hum Genet. , vol.89 , Issue.1 , pp. 82-93
    • Wu, M.C.1    Lee, S.2    Cai, T.3    Li, Y.4    Boehnke, M.5    Lin, X.6
  • 29
    • 84880294630 scopus 로고    scopus 로고
    • General framework for meta-analysis of rare variants in sequencing association studies
    • 23768515 Jul
    • Lee S, Teslovich TM, Boehnke M, Lin X. General framework for meta-analysis of rare variants in sequencing association studies. Am J Hum Genet. 2013 Jul; 93(1):42-53. doi: 10.1016/j.ajhg.2013.05. 010 PMID: 23768515
    • (2013) Am J Hum Genet. , vol.93 , Issue.1 , pp. 42-53
    • Lee, S.1    Teslovich, T.M.2    Boehnke, M.3    Lin, X.4
  • 30
    • 79251619566 scopus 로고    scopus 로고
    • Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: Two genome-wide association studies
    • 21239051 Jan
    • Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, et al. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet. 2011 Jan; 377 (9763):383-392. doi: 10.1016/S0140-6736(10)61996-4 PMID: 21239051
    • (2011) Lancet. , vol.377 , Issue.9763 , pp. 383-392
    • Reilly, M.P.1    Li, M.2    He, J.3    Ferguson, J.F.4    Stylianou, I.M.5    Mehta, N.N.6
  • 31
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • 21890647 Sep
    • Cabili MN, Trapnell C, Goff L, Koziol M, Tazon-Vega B, Regev A, et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 2011 Sep; 25(18):1915-1927. doi: 10.1101/gad.17446611 PMID: 21890647
    • (2011) Genes Dev. , vol.25 , Issue.18 , pp. 1915-1927
    • Cabili, M.N.1    Trapnell, C.2    Goff, L.3    Koziol, M.4    Tazon-Vega, B.5    Regev, A.6
  • 32
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
    • Sep
    • Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012 Sep; 22(9):1775-1789. doi: 10.1101/gr.132159.111
    • (2012) Genome Res. , vol.22 , Issue.9 , pp. 1775-1789
    • Derrien, T.1    Johnson, R.2    Bussotti, G.3    Tanzer, A.4    Djebali, S.5    Tilgner, H.6


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