Economic impact of dementia by disease severity: exploring the relationship between stage of dementia and cost of care in Taiwan

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Ku, Li Jung Elizabeth ^a   Pai, Ming Chyi ^a   Shih, Pei Yu ^a  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BEHAVIOR DISORDER; CAREGIVER BURDEN; COGNITIVE DEFECT; CONTROLLED STUDY; COST OF ILLNESS; DEMENTIA; DISEASE ASSOCIATION; DISEASE SEVERITY; ECONOMIC EVALUATION; FEMALE; FUNCTIONAL DISEASE; HEALTH CARE COST; HUMAN; MALE; MEDICAL HISTORY; OUTCOME ASSESSMENT; SYNDROME DELINEATION; TAIWAN; VERY ELDERLY; CAREGIVER; COMMUNITY CARE; ECONOMICS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PSYCHOLOGY; SEVERITY OF ILLNESS INDEX;

AGED; AGED, 80 AND OVER; CAREGIVERS; COMMUNITY HEALTH SERVICES; COST OF ILLNESS; DEMENTIA; FEMALE; HEALTH CARE COSTS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; SEVERITY OF ILLNESS INDEX; TAIWAN;

EID: 84959421237     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148779     Document Type: Article

References (35)

1. Wimo A, Prince MJ. World Alzheimer Report 2010: The global economic impact of dementia: Alzheimer's Disease International; 2010.
2. Alzheimer's Association. 2015 Alzheimer's disease facts and figures. Alzheimer's & dementia: The journal of the Alzheimer's Association. 11(3):332.
3. Quentin W, Riedel-Heller SG, Luppa M, Rudolph A, Konig HH. Cost-of-illness studies of dementia: a systematic review focusing on stage dependency of costs. Acta psychiatrica Scandinavica. 2010; 121 (4):243-59. doi:10.1111/j.1600-0447.2009.01461.x PMID: 19694634.
4. Wimo A, Prince MJ, Guerchet M, Ali G-C, Wu Y-T, Prina M. World Alzheimer Report 2015: The global impact of dementia. Alzheimer's Disease International, 2015.
5. Mauskopf J, Racketa J, Sherrill E. Alzheimer's disease: The strength of association of costs with different measures of disease severity. The journal of nutrition, health & aging. 2010; 14(8):655-63. Epub 2010/10/06. PMID: 20922342.
6. Schaller S, Mauskopf J, Kriza C, Wahlster P, Kolominsky-Rabas PL. The main cost drivers in dementia: a systematic review. International journal of geriatric psychiatry. 2015; 30(2):111-29. doi:10.1002/gps.4198PMID: 25320002.
7. Lim J, Goh J, Chionh HL, Yap P. Why do patients and their families not use services for dementia? Perspectives from a developed Asian country. International Psychogeriatrics. 2012; 24(10):1571-80. doi:10.1017/S1041610212000919PMID: 22647248.
8. Schwarzkopf L, Menn P, Kunz S, Holle R, Lauterberg J, Marx P, et al. Costs of care for dementia patients in community setting: an analysis for mild and moderate disease stage. Value Health. 2011; 14 (6):827-35. Epub 2011/09/15. doi:10.1016/j.jval.2011.04.005 PMID: 21914502.
9. Chong MS, Tan WS, Chan M, Lim WS, Ali N, Ang YY, et al. Cost of informal care for community-dwelling mild-moderate dementia patients in a developed Southeast Asian country. International psychogeriatrics. 2013; 25(09):1475-83doi:10.1017/S1041610213000707.
10. Fuh JL, Wang SJ. Dementia in Taiwan: past, present, and future. Acta Neurologica Taiwanica. 2008; 17(3):153-61. PMID: 18975520.
11. Sun Y, Lee HJ, Yang SC, Chen TF, Lin KN, Lin CC, et al. A nationwide survey of mild cognitive impairment and dementia, including very mild dementia, in Taiwan. PLOS one. 2014; 9(6):e100303. Epub 2014/06/19. doi:10.1371/journal.pone.0100303 PMID: 24940604; PubMed Central PMCID: PMC4062510.
12. Chou LF, Chang CW, Fu JL, Wang SJ. The economic costs of dementia in Taiwan. Natil Chengchi Univ J. 2000; 82:1-26.
13. Kuo YC, Lan CF, Chen LK, Lan VM. Dementia care costs and the patient's quality of life (QoL) in Taiwan: home versus institutional care services. Archives of gerontology and geriatrics. 2010; 51(2):159- 63. Epub2010/01/01.doi:10.1016/j.archger.2009.10.001 PMID: 20042244.
14. Jonsson L, Wimo A. The cost of dementia in Europe: a review of the evidence, and methodological considerations. PharmacoEconomics. 2009; 27(5):391-403. PMID: 19586077. doi:10.2165/00019053-200927050-00004.
15. Rapp T, Andrieu S, Molinier L, Grand A, Cantet C, Mullins CD, et al. Exploring the relationship between Alzheimer's disease severity and longitudinal costs. Value in health: The journal of the International Society for Pharmacoeconomics and Outcomes Research. 2012; 15(3):412-9. doi:10.1016/j.jval.2012.02.003 PMID: 22583450.
16. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition1994.
17. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. The British Journal of Psychiatry. 1982; 140(6):566-72.
18. Chuo LJ, Sheu WHH, Pai MC, Kuo YM. Genotype and Plasma Concentration of Cystatin C in Patients with Late-Onset Alzheimer Disease. Dementia and Geriatric Cognitive Disorders. 2007; 23(4):251-7. PMID: 17310123.
19. Bureau of National Health Insurance. Reimbursement rule of drugs acting on the nervous system Taiwan 2013. Available: http://www.nhi.gov.tw/. Accessed 9 July 2013.
20. Benaim C, Froger J, Compan B, Pelissier J. The assessment of autonomy in elderly people. Ann Readapt Med Phys. 2005; 48(6):336-40. PMID: 15932780.
21. Thomas P, Lalloué F, Preux PM, Hazif-Thomas C, Pariel S, Inscale R, et al. Dementia patients caregivers quality of life: The PIXEL study. International journal of geriatric psychiatry. 2006; 21(1):50-6. PMID: 16323256.
22. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The Neuropsychiatric Inventory comprehensive assessment of psychopathology in dementia. Neurology. 1994; 44 (12):2308-. PMID: 7991117.
23. Wimo A, Gustavsson A, Jonsson L, Winblad B, Hsu MA, Gannon B. Application of Resource Utilization in Dementia (RUD) instrument in a global setting. Alzheimer's & dementia: The journal of the Alzheimer's Association. 2013; 9(4):429-35 e17. Epub 2012/11/13doi:10.1016/j.jalz.2012.06.008 PMID: 23142433.
24. Ministry of Health and Welfare. Social Welfare Subsidized Items and Schedule 2014 [updated 2014/09/24]. Available: http://www.sfaa.gov.tw/SFAA/Pages/Detail.aspx?nodeid=428&pid=3156.
25. International Monetary Fund. World Economic Outlook Database 2015. Available: https://www.imf.org/external/pubs/ft/weo/2015/01/weodata/index.aspx.
26. Manning WG, Mullahy J. Estimating log models: To transform or not to transform? Journal of health economics. 2001; 20(4):461-94. PMID: 11469231.
27. Lafortune L, Béland F, Bergman H, Ankri J. Health state profiles and service utilization in community-living elderly. Medical care. 2009; 47(3):286-94. doi:10.1097/MLR.0b013e3181894293PMID: 19165121.
28. Jönsson L, Jönhagen ME, Kilander L, Soininen H, Hallikainen M, Waldemar G, et al. Determinants of costs of care for patients with Alzheimer's disease. International journal of geriatric psychiatry. 2006; 21 (5):449-59. PMID: 16676288.
29. Chan SWC. Family Caregiving in Dementia: The Asian Perspective of a Global Problem. Dementia and Geriatric Cognitive Disorders. 2010; 30(6):469-78. doi:10.1159/000322086WOS:000286429200005. PMID: 21252540.
30. Hill J, F H, Thomas SK, Chang S. Functional impairment, healthcare costs and the prevalence of institutionalization in patients with Alzheimer's disease and other dementias. Pharmacoeconomics. 2006; 24 (3):265-80. PMID: 16519548.
31. Leicht H, Konig HH, Stuhldreher N, Bachmann C, Bickel H, Fuchs A, et al. Predictors of costs in dementia in a longitudinal perspective. PLOS One. 2013; 8(7):e70018doi:10.1371/journal.pone.0070018 PMID: 23875017; PubMed Central PMCID: PMCPMC3715502.
32. Small GW, M D, Brooks RL, Papadopoulos G. The impact of symptom severity on the cost of Alzheimer's disease. Journal of the American Geriatrics Society. 2002; 50(2):321-7. PMID: 12028215.
33. Neubauer S, Holle R, Menn P, Grossfeld-Schmitz M, Graesel E. Measurement of informal care time in a study of patients with dementia. International psychogeriatrics/IPA. 2008; 20(6):1160-76. doi:10.1017/S1041610208007564 PMID: 18606044.
34. Zhu CW, Leibman C, McLaughlin T, Zbrozek AS, Scarmeas N, Albert M, et al. Patient dependence and longitudinal changes in costs of care in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 2008; 26(5):416-23. Epub 2008/10/24. doi:10.1159/000164797 PMID: 18946219; PubMed Central PMCID: PMC2631662.
35. Gerves C, Chauvin P, Bellanger MM. Evaluation of full costs of care for patients with Alzheimer's disease in France: The predominant role of informal care. Health Policy. 2014; 116(1):114-22. doi:10.1016/j.healthpol.2014.01.001 PMID: 24461717.