Cholesteryl esters stabilize human CD1c conformations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 9, 2016, Pages E1266-E1275

  Mansour, Salah ^a,b   Tocheva, Anna S ^a   Cave Ayland, Chris ^b   Machelett, Moritz M ^b   Sander, Barbara ^b   Lissin, Nikolai M ^c   Molloy, Peter E ^c   Baird, Mark S ^d   Stübs, Gunthard ^e   Schröder, Nicolas W J ^f   Schumann, Ralf R ^g   Rademann, Jörg ^h   Postle, Anthony D ^a   Jakobsen, Bent K ^c   Marshall, Ben G ^a,b   Gosain, Rajendra ^b   Elkington, Paul T ^a,b   Elliott, Tim ^a,b   Skylaris, Chris Kriton ^b   Essex, Jonathan W ^b   Tews, Ivo ^b   Gadola, Stephan D ^a,b,i   more..

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c Immunocore Limited   (United Kingdom)

^d BANGOR UNIVERSITY   (United Kingdom)

^e UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^f OTTO VON GUERICKE UNIVERSITY   (Germany)

^g CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^h FREIE UNIVERSITÄT BERLIN   (Germany)

ⁱ NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antigen presentation; CD1; Cholesteryl ester; Lipid antigen; Tcell

Indexed keywords

ACYLATED STERYL GLYCOSIDE; CD1C ANTIGEN; CHOLESTEROL ESTER; GLYCOSIDE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; CD1 ANTIGEN; CD1C PROTEIN, HUMAN; CD1D ANTIGEN; GLYCOPROTEIN;

ALPHA HELIX; ARTICLE; CONTROLLED STUDY; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN REFOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; T LYMPHOCYTE; CHEMISTRY; HUMAN; IMMUNOLOGY; METABOLISM;

ANTIGENS, CD1; ANTIGENS, CD1D; CHOLESTEROL ESTERS; GLYCOPROTEINS; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; T-LYMPHOCYTES;

EID: 84959386279     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1519246113     Document Type: Article

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