Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes

Oxidative Medicine and Cellular Longevity

Volumn 2016, Issue , 2016, Pages

  Fan, Zhuo ^a   Wen, Ting ^a   Chen, Yaoxu ^a   Huang, Lijie ^a   Lin, Wei ^a   Yin, Chunxia ^a   Tan, Wen ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOELECTRIC POTENTIALS; CARDIOVASCULAR SYSTEM; CHEMICAL ACTIVATION; DRUG THERAPY; METABOLISM;

ACID HYDROLYSIS; ANTI-HYPERTENSION; CARDIAC HYPERTROPHY; CURRENT AMPLITUDE; METABOLIC PATHWAYS; METABOLIC STRESS; PATHOLOGICAL CONDITIONS; VENTRICULAR MYOCYTES;

MITOCHONDRIA;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCIUM CHANNEL L TYPE; DIAZOXIDE; FLAVOPROTEIN; GLIBENCLAMIDE; ISOSTEVIOL; KAURANE DERIVATIVE; PINACIDIL; REACTIVE OXYGEN METABOLITE;

ACTION POTENTIAL; ANIMAL; CARDIAC MUSCLE CELL; CHANNEL GATING; CYTOLOGY; DRUG EFFECTS; FLUORESCENCE; GUINEA PIG; HEART VENTRICLE; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; SARCOLEMMA; TIME FACTOR;

ACETYLCYSTEINE; ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS, L-TYPE; DIAZOXIDE; DITERPENES, KAURANE; FLAVOPROTEINS; FLUORESCENCE; GLYBURIDE; GUINEA PIGS; HEART VENTRICLES; ION CHANNEL GATING; KATP CHANNELS; MITOCHONDRIA; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; PINACIDIL; REACTIVE OXYGEN SPECIES; SARCOLEMMA; TIME FACTORS;

EID: 84959378240     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2016/6362812     Document Type: Article

References (46)

1. A. Noma, "ATP-regulated K+ channels in cardiac muscle," Nature, vol. 305, no. 5930, pp. 147-148, 1983.
2. F. M. Ashcroft, "Adenosine 5-triphosphate-sensitive potassium channels," Annual Review of Neuroscience, vol. 11, pp. 97-118, 1988.
3. A. Terzic, A. Jahangir, and Y. Kurachi, "Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs," The American Journal of Physiology- Cell Physiology, vol. 269, no. 3, pp. C525-C545, 1995.
4. N. Inagaki, T. Gonoi, J. P. Clement et al., "Reconstitution of KATP: An inward rectifier subunit plus the sulfonylurea receptor," Science, vol. 270, no. 5239, pp. 1166-1170, 1995.
5. S. J. Tucker, F. M. Gribble,C. Zhao, S. Trapp, and F. M. Ashcroft, "Truncation of Kir6. 2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor," Nature, vol. 387, no. 6629, pp. 179-183, 1997.
6. M. A. Burke, R. K. Mutharasan, andH. Ardehali, "The sulfonylurea receptor, an atypical ATP-binding cassette protein, and its regulation of the KATP channel," Circulation Research, vol. 102, no. 2, pp. 164-176, 2008.
7. T. Miki, K. Nagashima, F. Tashiro et al., "Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice," Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 18, pp. 10402-10406, 1998.
8. F. M. Ashcroft, "ATP-sensitive potassium channelopathies: focus on insulin secretion," Journal of Clinical Investigation, vol. 115, no. 8, pp. 2047-2058, 2005.
9. G. C. Kane, X.-K. Liu, S. Yamada, T. M. Olson, and A. Terzic, "Cardiac KATP channels in health and disease," Journal of Molecular and Cellular Cardiology, vol. 38, no. 6, pp. 937-943, 2005.
10. M. V. Cohen, C. P. Baines, and J. M. Downey, "Ischemic preconditioning: from adenosine receptor to KATP channel," Annual Review of Physiology, vol. 62, no. 1, pp. 79-109, 2000.
11. W. C. Cole,C. D. McPherson, andD. Sontag, "ATP-regulatedK+ channels protect themyocardium against ischemia/reperfusion damage," Circulation Research, vol. 69, no. 3, pp. 571-581, 1991.
12. G. J. Gross and J. A. Auchampach, "Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs," Circulation Research, vol. 70, no. 2, pp. 223-233, 1992.
13. T. Mizumura, K. Nithipatikom, and G. J. Gross, "Bimakalim, an ATP-sensitive potassium channel opener, mimics the effects of ischemic preconditioning to reduce infarct size, adenosine release, and neutrophil function in dogs," Circulation, vol. 92, no. 5, pp. 1236-1245, 1995.
14. K. D. Garlid, P. Dos Santos, Z.-J. Xie, A. D. T. Costa, and P. Paucek, "Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K+ channel in cardiac function and cardioprotection," Biochimica et Biophysica Acta (BBA)- Bioenergetics, vol. 1606, no. 1-3, pp. 1-21, 2003.
15. D. M. Hodgson, L. V. Zingman, G. C. Kane et al., "Cellular remodeling in heart failure disrupts KATP channel-dependent stress tolerance," The EMBO Journal, vol. 22, no. 8, pp. 1732-1742, 2003.
16. H. Takaba, T. Nagao, S. Ibayashi, T. Kitazono, K. Fujii, and M. Fujishima, "Altered cerebrovascular response to a potassium channel opener in hypertensive rats," Hypertension, vol. 28, no. 1, pp. 143-146, 1996.
17. F. Yuan, N. R. Brandt, J. M. Pinto, B. J. Wasserlauf, R. J. Myerburg, and A. L. Bassett, "Hypertrophy decreases cardiac KATP channel responsiveness to exogenous and locally generated (Glycolytic) ATP," Journal ofMolecular and Cellular Cardiology, vol. 29, no. 10, pp. 2837-2848, 1997.
18. Z. V. Alvin, R. M. Millis, W. Hajj-Mousssa, and G. E. Haddad, "ATP-sensitive potassium channel currents in eccentrically hypertrophied cardiac myocytes of volume-overloaded rats," International Journal of Cell Biology, vol. 2011, Article ID838951, 6 pages, 2011.
19. J. M. C. Geuns, "Stevioside," Phytochemistry, vol. 64, no. 5, pp. 913-921, 2003.
20. M. S. Melis and A. R. Sainati, "Participation of prostaglandins in the effect of stevioside on rat renal function and arterial pressure," Brazilian Journal of Medical and Biological Research, vol. 24, no. 12, pp. 1269-1276, 1991.
21. P. Chan, D.-Y. Xu, J.-C. Liu et al., "The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats," Life Sciences, vol. 63, no. 19, pp. 1679-1684, 1998.
22. Y.-H. Hsu, J.-C. Liu, P.-F. Kao et al., "Antihypertensive effect of stevioside in different strains of hypertensive rats," Chinese Medical Journal, vol. 65, no. 1, pp. 1-6, 2002.
23. M.-H. Hsieh, P. Chan, Y.-M. Sue et al., "Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: A two-year, randomized, placebo-controlled study," Clinical Therapeutics, vol. 25, no. 11, pp. 2797-2808, 2003.
24. K. Yasukawa, S. Kitanaka, and S. Seo, "Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin," Biological and Pharmaceutical Bulletin, vol. 25,no. 11, pp. 1488-1490, 2002.
25. J.-C. Liu, P.-F. Kao, M.-H. Hsieh, Y.-J. Chen, and P. Chan, "The antihypertensive effect of stevioside derivative isosteviol in spontaneously hypertensive rats," Acta Cardiologica Sinica, vol. 17, no. 3, pp. 133-140, 2001.
26. J. Ma, Z. Ma, J. Wang et al., "Isosteviol reduces plasma glucose levels in the intravenous glucose tolerance test in Zucker diabetic fatty rats,"Diabetes, Obesity andMetabolism, vol. 9, no. 4, pp. 597-599, 2007.
27. W. Tan, "The use of kauranes compounds in the manufacture medicament," PCT Patent WO/110383, World Intelleture Property Organization, 2005.
28. D. Xu, S. Zhang, D. Foster Jr., and J. Wang, "The effects of isosteviol against myocardium injury induced by ischaemiareperfusion in the isolated guinea pig heart," Clinical and Experimental Pharmacology and Physiology, vol. 34, no. 5-6, pp. 488-493, 2007.
29. D. Xu, Y. Li, J. Wang, A. K. Davey, S. Zhang, and A. M. Evans, "The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury," Life Sciences, vol. 80, no. 4, pp. 269-274, 2007.
30. R. Padrini, S. Bova, G. Cargnelli, D. Piovan, and M. Ferrari, "Effects of pinacidil on guinea-pig isolated perfused heart with particular reference to the proarrhythmic effect," British Journal of Pharmacology, vol. 105, no. 3, pp. 715-719, 1992.
31. Y. Liu, T. Sato, B. O'Rourke, and E. Marban, "Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?" Circulation, vol. 97, no. 24, pp. 2463-2469, 1998.
32. P. Jezek and L. Hlavatá, "Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism," The International Journal of Biochemistry & Cell Biology, vol. 37, no. 12, pp. 2478-2503, 2005.
33. A. J. Lambert and M. D. Brand, "Reactive oxygen species production by mitochondria," Methods in Molecular Biology, vol. 554, pp. 165-181, 2009.
34. J. F. Turrens, "Mitochondrial formation of reactive oxygen species," Journal of Physiology, vol. 552, no. 2, pp. 335-344, 2003.
35. T. Pain,X.-M. Yang, S. D. Critz et al., "Openingofmitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals," Circulation Research, vol. 87, no. 6, pp. 460-466, 2000.
36. M. V. Cohen, X.-M. Yang, G. S. Liu, G. Heusch, and J. M. Downey, "Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and openingmitochondrial K(ATP) channels," Circulation Research, vol. 89, no. 3, pp. 273-278, 2001.
37. K. D. Garlid, A. D. T. Costa, C. L. Quinlan, S. V. Pierre, and P. Dos Santos, "Cardioprotective signaling to mitochondria," Journal of Molecular and Cellular Cardiology, vol. 46, no. 6, pp. 858-866, 2009.
38. A. Sukhodub, S. Jovanovíc,D. U. Qingyou et al., "AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmalATP-sensitive K+ channels," Journal of Cellular Physiology, vol. 210, no. 1, pp. 224-236, 2007.
39. K. Hu, C. S. Huang, Y. N. Jan, and L. Y. Jan, "ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C," Neuron, vol. 38, no. 3, pp. 417-432, 2003.
40. A. G. Edwards, M. L. Rees, R. A. Gioscia et al., "PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance tomyocardial infarction,"The Journal of Physiology, vol. 587, no. 23, pp. 5723-5737, 2009.
41. P. J. Hanley, M. Mickel, M. Löffler, U. Brandt, and J. Daut, "KATP channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart," Journal of Physiology, vol. 542, part 3, pp. 735-741, 2002.
42. N. D'hahan, C. Moreau, A. L. Prost et al., "Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP," Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 21, pp. 12162-12167, 1999.
43. A. P. Wojtovich and P. S. Brookes, "The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation ofmitochondrial KATP channels," Basic Research in Cardiology, vol. 104, no. 2, pp. 121-129, 2009.
44. A. P. Wojtovich, K. W. Nehrke, and P. S. Brookes, "The mitochondrial complex II and ATP-sensitive potassium channel interaction: quantitation of the channel in heartmitochondria," Acta Biochimica Polonica, vol. 57, no. 4, pp. 431-434, 2010.
45. E. L. Holmuhamedov, A. Jahangir, A. Oberlin, A. Komarov, M. Colombini, and A. Terzic, "Potassium channel openers are uncoupling protonophores: implication in cardioprotection," FEBS Letters, vol. 568, no. 1-3, pp. 167-170, 2004.
46. M. Bienengraeber, A. E. Alekseev,M. R. Abrahamet al., "ATPase activity of the sulfonylurea receptor: A catalytic function for the KATP channel complex," The FASEB Journal, vol. 14, no. 13, pp. 1943-1952, 2000.