Is immune system-related hypertension associated with ovarian hormone deficiency?

Experimental Physiology

Volumn 101, Issue 3, 2016, Pages 368-374

  Sandberg, Kathryn ^a   Ji, Hong ^a   Einstein, Gillian ^b   Au, April ^b   Hay, Meredith ^c  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 8; RANTES; TUMOR NECROSIS FACTOR ALPHA; SEX HORMONE;

ADAPTIVE IMMUNITY; ARTICLE; BLOOD PRESSURE REGULATION; BRAIN REGION; CELL INFILTRATION; DISEASE ASSOCIATION; DISEASE COURSE; ESTROGEN THERAPY; FEMALE; GENE EXPRESSION; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HORMONE SYNTHESIS; HUMAN; HYPERTENSION; IMMUNE SYSTEM; IMMUNE SYSTEM RELATED HYPERTENSION; NONHUMAN; OVARIAN HORMONE DEFICIENCY; OVARY DISEASE; SEX DIFFERENCE; T LYMPHOCYTE; UPREGULATION; BLOOD PRESSURE; DEFICIENCY; IMMUNOLOGY; METABOLISM; OVARY; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT;

BLOOD PRESSURE; FEMALE; GONADAL STEROID HORMONES; HUMANS; HYPERTENSION; IMMUNE SYSTEM; OVARY; SEX CHARACTERISTICS;

EID: 84959375998     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/EP085149     Document Type: Article

References (37)

1. Abu-Taha M, Rius C, Hermenegildo C, Noguera I, Cerda-Nicolas JM, Issekutz AC, Jose PJ, Cortijo J, Morcillo EJ & Sanz MJ (2009). Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan. J Immunol 183, 1393-1402.
2. Amador CA, Barrientos V, Peña J, Herrada AA, González M, Valdés S, Carrasco L, Alzamora R, Figueroa F, Kalergis AM & Michea L (2014). Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. Hypertension 63, 797-803.
3. Amadori A, Zamarchi R, De Silvestro G, Forza G, Cavatton G, Danieli GA, Clementi M & Chieco-Bianchi L (1995). Genetic control of the CD4/CD8 T-cell ratio in humans. Nat Med 1, 1279-1283.
4. Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR & Cotman CW (2008). Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc Natl Acad Sci USA 105, 15605-15610.
5. De Miguel C, Lund H & Mattson DL (2011). High dietary protein exacerbates hypertension and renal damage in Dahl SS rats by increasing infiltrating immune cells in the kidney. Hypertension 57, 269-274.
6. Deswal A, Petersen NJ, Feldman AM, Young JB, White BG & Mann DL (2001). Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST). Circulation 103, 2055-2059.
7. DonCarlos LL, Azcoitia I & Garcia-Segura LM (2009). Neuroprotective actions of selective estrogen receptor modulators. Psychoneuroendocrinology 34(Suppl 1), S113-S122.
8. Foks AC, Lichtman AH & Kuiper J (2015). Treating atherosclerosis with regulatory T cells. Arterioscler Thromb Vasc Biol 35, 280-287.
9. Guzik TJ, Hoch NE, Brown KA, McCann LA, Rahman A, Dikalov S, Goronzy J, Weyand C & Harrison DG (2007). Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med 204, 2449-2460.
10. Harrison DG, Guzik TJ, Lob HE, Madhur MS, Marvar PJ, Thabet SR, Vinh H & Weyand CM (2011). Inflammation, immunity, and hypertension. Hypertension 57, 132-140.
11. Hinojosa-Laborde C, Craig T, Zheng W, Ji H, Haywood JR & Sandberg K (2004). Ovariectomy augments hypertension in aging female Dahl salt-sensitive rats. Hypertension 44, 405-409.
12. Ji H, Zheng W, Li X, Liu J, Wu X, Zhang MA, Umans JG, Hay M, Speth RC, Dunn SE & Sandberg K (2014). Sex-specific T cell regulation of angiotensin II-dependent hypertension. Hypertension 64, 573-582.
13. Johann S & Beyer C (2013). Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia. J Steroid Biochem Mol Biol 137, 71-81.
14. Korn T, Bettelli E, Oukka M & Kuchroo VK (2009). IL-17 and Th17 cells. Annu Rev Immunol 27, 485-517.
15. Lob HE, Schultz D, Marvar PJ, Davisson RL & Harrison DG (2012). Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension 61, 382-387.
16. + T cells to initiate and augment acute cardiac inflammatory response to high blood pressure. J Immunol 192, 3365-3373.
17. Mattson DL, Lund H, Guo C, Rudemiller N, Geurts AM & Jacob H (2013). Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage. Am J Physiol Regul Integr Comp Physiol 304, R407-R414.
18. Miller AP, Chen YF, Xing D, Feng W & Oparil S (2003). Hormone replacement therapy and inflammation: interactions in cardiovascular disease. Hypertension 42, 657-663.
19. Pal L & Santoro N (2002). Premature ovarian failure (POF): discordance between somatic and reproductive aging. Ageing Res Rev 1, 413-423.
20. Pollow DP, Uhrlaub J, Romero-Aleshire MJ, Sandberg K, Nikolich-Zugich J, Brooks HL & Hay M (2014). Sex differences in T-lymphocyte tissue infiltration and development of angiotensin II hypertension. Hypertension 64, 384-390.
21. Rodríguez-Iturbe B, Quiroz Y, Ferrebuz A, Parra G & Vaziri ND (2004). Evolution of renal interstitial inflammation and NF-κB activation in spontaneously hypertensive rats. Am J Nephrol 24, 587-594.
22. Rodríguez-Iturbe B, Quiroz Y, Nava M, Bonet L, Chávez M, Herrera-Acosta J, Johnson RJ & Pons HA (2002). Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive rats. Am J Physiol Renal Physiol 282, F191-F201.
23. Rudemiller N, Lund H, Jacob HJ, Geurts AM, Mattson DL & Program PK (2014). CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. Hypertension 63, 559-564.
24. Sandberg K & Ji H (2012). Sex differences in primary hypertension. Biol Sex Differ 3, 7.
25. Sandberg K, Ji H & Hay M (2015). Sex-specific immune modulation of primary hypertension. Cell Immunol 294, 95-101.
26. Sárvári M, Hrabovszky E, Kalló I, Solymosi N, Likó I, Berchtold N, Cotman C & Liposits Z (2012). Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. J Neuroinflammation 9, 264.
27. Schulman IH, Aranda P, Raij L, Veronesi M, Aranda FJ & Martin R (2006). Surgical menopause increases salt sensitivity of blood pressure. Hypertension 47, 1168-1174.
28. Spence RD, Hamby ME, Umeda E, Itoh N, Du S, Wisdom AJ, Cao Y, Bondar G, Lam J, Ao Y, Sandoval F, Suriany S, Sofroniew MV & Voskuhl RR (2011). Neuroprotection mediated through estrogen receptor-α in astrocytes. Proc Natl Acad Sci USA 108, 8867-8872.
29. Staessen JA, Celis H & Fagard R (1998). The epidemiology of the association between hypertension and menopause. J Hum Hypertens 12, 587-592.
30. Staessen JA, Ginocchio G, Thijs L & Fagard R (1997). Conventional and ambulatory blood pressure and menopause in a prospective population study. J Hum Hypertens 11, 507-514.
31. Tipton AJ, Baban B & Sullivan JC (2012). Female spontaneously hypertensive rats have greater renal anti-inflammatory T lymphocyte infiltration than males. Am J Physiol Regul Integr Comp Physiol 303, R359-R367.
32. Tipton AJ, Baban B & Sullivan JC (2014). Female spontaneously hypertensive rats have a compensatory increase in renal regulatory T cells in response to elevations in blood pressure. Hypertension 64, 557-564.
33. Tipton AJ & Sullivan JC (2014). Sex differences in T cells in hypertension. Clin Ther 36, 1882-1900.
34. Xue B, Johnson AK & Hay M (2007). Sex differences in angiotensin II-induced hypertension. Braz J Med Biol Res 40, 727-734.
35. Xue B, Pamidimukkala J & Hay M (2005). Sex differences in the development of angiotensin II-induced hypertension in conscious mice. Am J Physiol Heart Circ Physiol 288, H2177-H2184.
36. Zhang MA, Rego D, Moshkova M, Kebir H, Chruscinski A, Nguyen H, Akkermann R, Stanczyk FZ, Prat A, Steinman L & Dunn SE (2012). Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way. Proc Natl Acad Sci USA 109, 9505-9510.
37. Zheng W, Ji H, Maric C, Wu X & Sandberg K (2008). Effect of dietary sodium on estrogen regulation of blood pressure in Dahl salt-sensitive rats. Am J Physiol Heart Circ Physiol 294, H1508-H1513.