메뉴 건너뛰기




Volumn 25, Issue 2, 2016, Pages 436-446

Impact of Metformin on the Severity and Outcomes of Acute Ischemic Stroke in Patients with Type 2 Diabetes Mellitus

Author keywords

Acute ischemic stroke; Acute stroke outcome; Diabetes mellitus; Metformin; Stroke severity

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; ANTICOAGULANT AGENT; ANTIHYPERTENSIVE AGENT; CALCIUM CHANNEL BLOCKING AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INCRETIN; INSULIN; METFORMIN; SULFONYLUREA; ANTIDIABETIC AGENT;

EID: 84959369077     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2015.10.016     Document Type: Article
Times cited : (57)

References (33)
  • 1
    • 19944434137 scopus 로고    scopus 로고
    • Type 2 diabetes and risk of non-embolic ischaemic stroke in Japanese men and women
    • H. Iso, H. Imano, A. Kitamura, and et al. Type 2 diabetes and risk of non-embolic ischaemic stroke in Japanese men and women Diabetologia 47 2004 2137 2144
    • (2004) Diabetologia , vol.47 , pp. 2137-2144
    • Iso, H.1    Imano, H.2    Kitamura, A.3
  • 2
    • 77953821528 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies
    • N. Sarwar, Gao P., S.R. Seshasai, and et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies Lancet 375 2010 2215 2222
    • (2010) Lancet , vol.375 , pp. 2215-2222
    • Sarwar, N.1    Gao, P.2    Seshasai, S.R.3
  • 3
    • 65649106228 scopus 로고    scopus 로고
    • Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: A meta-analysis of randomised controlled trials
    • K.K. Ray, S.R. Seshasai, S. Wijesuriya, and et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials Lancet 373 2009 1765 1772
    • (2009) Lancet , vol.373 , pp. 1765-1772
    • Ray, K.K.1    Seshasai, S.R.2    Wijesuriya, S.3
  • 4
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS)
    • UK Prospective Diabetes Study (UKPDS) Group Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) Lancet 352 1998 854 865
    • (1998) Lancet , vol.352 , pp. 854-865
  • 5
    • 84893347537 scopus 로고    scopus 로고
    • Metformin-inclusive therapy reduces the risk of stroke in patients with diabetes: A 4-year follow-up study
    • Cheng Y.Y., H.B. Leu, Chen T.J., and et al. Metformin-inclusive therapy reduces the risk of stroke in patients with diabetes: a 4-year follow-up study J Stroke Cerebrovasc Dis 23 2014 e99 e105
    • (2014) J Stroke Cerebrovasc Dis , vol.23 , pp. e99-e105
    • Cheng, Y.Y.1    Leu, H.B.2    Chen, T.J.3
  • 6
    • 79952069056 scopus 로고    scopus 로고
    • Sulfonylurea use before stroke does not influence outcome
    • C.G. Favilla, M.T. Mullen, M. Ali, and et al. Sulfonylurea use before stroke does not influence outcome Stroke 42 2011 710 715
    • (2011) Stroke , vol.42 , pp. 710-715
    • Favilla, C.G.1    Mullen, M.T.2    Ali, M.3
  • 7
    • 0034825944 scopus 로고    scopus 로고
    • Sulfonylurea drugs do not influence initial stroke severity and in-hospital outcome in stroke patients with diabetes
    • M. Weih, N. Amberger, S. Wegener, and et al. Sulfonylurea drugs do not influence initial stroke severity and in-hospital outcome in stroke patients with diabetes Stroke 32 2001 2029 2032
    • (2001) Stroke , vol.32 , pp. 2029-2032
    • Weih, M.1    Amberger, N.2    Wegener, S.3
  • 8
    • 78149357102 scopus 로고    scopus 로고
    • Effects of metformin in experimental stroke
    • Li J., S.E. Benashski, V.R. Venna, and et al. Effects of metformin in experimental stroke Stroke 41 2010 2645 2652
    • (2010) Stroke , vol.41 , pp. 2645-2652
    • Li, J.1    Benashski, S.E.2    Venna, V.R.3
  • 9
    • 84902547561 scopus 로고    scopus 로고
    • Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke
    • V.R. Venna, Li J., M.D. Hammond, and et al. Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke Eur J Neurosci 39 2014 2129 2138
    • (2014) Eur J Neurosci , vol.39 , pp. 2129-2138
    • Venna, V.R.1    Li, J.2    Hammond, M.D.3
  • 10
    • 0023889706 scopus 로고
    • Interobserver agreement for the assessment of handicap in stroke patients
    • J.C. van Swieten, P.J. Koudstaal, M.C. Visser, and et al. Interobserver agreement for the assessment of handicap in stroke patients Stroke 19 1988 604 607
    • (1988) Stroke , vol.19 , pp. 604-607
    • Van Swieten, J.C.1    Koudstaal, P.J.2    Visser, M.C.3
  • 11
    • 65549111017 scopus 로고    scopus 로고
    • Revised equations for estimated GFR from serum creatinine in Japan
    • S. Matsuo, E. Imai, M. Horio, and et al. Revised equations for estimated GFR from serum creatinine in Japan Am J Kidney Dis 53 2009 982 992
    • (2009) Am J Kidney Dis , vol.53 , pp. 982-992
    • Matsuo, S.1    Imai, E.2    Horio, M.3
  • 12
    • 75149130955 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association Diagnosis and classification of diabetes mellitus Diabetes Care 33 Suppl 1 2010 S62 S69
    • (2010) Diabetes Care , vol.33 , pp. S62-S69
  • 13
    • 0025412531 scopus 로고
    • Special report from the National Institute of Neurological Disorders and Stroke. Classification of cerebrovascular diseases III
    • Special report from the National Institute of Neurological Disorders and Stroke. Classification of cerebrovascular diseases III Stroke 21 1990 637 676
    • (1990) Stroke , vol.21 , pp. 637-676
  • 14
    • 0027514354 scopus 로고
    • Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment
    • H.P. Adams Jr, B.H. Bendixen, L.J. Kappelle, and et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment Stroke 24 1993 35 41
    • (1993) Stroke , vol.24 , pp. 35-41
    • Adams, H.P.1    Bendixen, B.H.2    Kappelle, L.J.3
  • 15
    • 0024328055 scopus 로고
    • Measurements of acute cerebral infarction: A clinical examination scale
    • T. Brott, H.P. Adams Jr, C.P. Olinger, and et al. Measurements of acute cerebral infarction: a clinical examination scale Stroke 20 1989 864 870
    • (1989) Stroke , vol.20 , pp. 864-870
    • Brott, T.1    Adams, H.P.2    Olinger, C.P.3
  • 16
    • 0344299275 scopus 로고    scopus 로고
    • Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
    • H.P. Adams Jr, P.H. Davis, E.C. Leira, and et al. Baseline NIH Stroke Scale score strongly predicts outcome after stroke: a report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Neurology 53 1999 126 131
    • (1999) Neurology , vol.53 , pp. 126-131
    • Adams, H.P.1    Davis, P.H.2    Leira, E.C.3
  • 17
    • 84872296782 scopus 로고    scopus 로고
    • Effect of previous statin therapy on severity and outcome in ischemic stroke patients: A population-based study
    • C. Aboa-Eboule, C. Binquet, A. Jacquin, and et al. Effect of previous statin therapy on severity and outcome in ischemic stroke patients: a population-based study J Neurol 260 2013 30 37
    • (2013) J Neurol , vol.260 , pp. 30-37
    • Aboa-Eboule, C.1    Binquet, C.2    Jacquin, A.3
  • 18
    • 84872929861 scopus 로고    scopus 로고
    • Statin therapy and outcome after ischemic stroke: Systematic review and meta-analysis of observational studies and randomized trials
    • D. Ni Chroinin, K. Asplund, S. Asberg, and et al. Statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and randomized trials Stroke 44 2013 448 456
    • (2013) Stroke , vol.44 , pp. 448-456
    • Ni Chroinin, D.1    Asplund, K.2    Asberg, S.3
  • 19
    • 83455234919 scopus 로고    scopus 로고
    • Effect of prior medical treatments on ischemic stroke severity and outcome
    • S. Sacco, D. Toni, A.A. Bignamini, and et al. Effect of prior medical treatments on ischemic stroke severity and outcome Funct Neurol 26 2011 133 139
    • (2011) Funct Neurol , vol.26 , pp. 133-139
    • Sacco, S.1    Toni, D.2    Bignamini, A.A.3
  • 20
    • 51449085994 scopus 로고    scopus 로고
    • Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: A double-blind, active and placebo-controlled study
    • H.C. Diener, R.L. Sacco, S. Yusuf, and et al. Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study Lancet Neurol 7 2008 875 884
    • (2008) Lancet Neurol , vol.7 , pp. 875-884
    • Diener, H.C.1    Sacco, R.L.2    Yusuf, S.3
  • 21
    • 25444522320 scopus 로고    scopus 로고
    • Angiotensin 2 type 2 receptor activity and ischemic stroke severity
    • B. Ovbiagele, C.S. Kidwell, S. Starkman, and et al. Angiotensin 2 type 2 receptor activity and ischemic stroke severity Neurology 65 2005 851 854
    • (2005) Neurology , vol.65 , pp. 851-854
    • Ovbiagele, B.1    Kidwell, C.S.2    Starkman, S.3
  • 22
    • 33745943872 scopus 로고    scopus 로고
    • Previous use of aspirin and baseline stroke severity: An analysis of 17,850 patients in the International Stroke Trial
    • S. Ricci, S. Lewis, P. Sandercock, and et al. Previous use of aspirin and baseline stroke severity: an analysis of 17,850 patients in the International Stroke Trial Stroke 37 2006 1737 1740
    • (2006) Stroke , vol.37 , pp. 1737-1740
    • Ricci, S.1    Lewis, S.2    Sandercock, P.3
  • 23
    • 0035214917 scopus 로고    scopus 로고
    • Effect of prior aspirin use on stroke severity in the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
    • J.L. Wilterdink, B. Bendixen, H.P. Adams Jr, and et al. Effect of prior aspirin use on stroke severity in the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Stroke 32 2001 2836 2840
    • (2001) Stroke , vol.32 , pp. 2836-2840
    • Wilterdink, J.L.1    Bendixen, B.2    Adams, H.P.3
  • 24
    • 80053312968 scopus 로고    scopus 로고
    • Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke: The Fukuoka Stroke Registry
    • M. Kamouchi, T. Matsuki, J. Hata, and et al. Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke: the Fukuoka Stroke Registry Stroke 42 2011 2788 2794
    • (2011) Stroke , vol.42 , pp. 2788-2794
    • Kamouchi, M.1    Matsuki, T.2    Hata, J.3
  • 25
    • 84914707751 scopus 로고    scopus 로고
    • Antidiabetic treatment, stroke severity and outcome
    • D. Magkou, and K. Tziomalos Antidiabetic treatment, stroke severity and outcome World Journal of Diabetes 5 2014 84 88
    • (2014) World Journal of Diabetes , vol.5 , pp. 84-88
    • Magkou, D.1    Tziomalos, K.2
  • 26
    • 0030953564 scopus 로고    scopus 로고
    • Stroke recurrence: Predictors, severity, and prognosis. The Copenhagen Stroke Study
    • H.S. Jorgensen, H. Nakayama, J. Reith, and et al. Stroke recurrence: predictors, severity, and prognosis. The Copenhagen Stroke Study Neurology 48 1997 891 895
    • (1997) Neurology , vol.48 , pp. 891-895
    • Jorgensen, H.S.1    Nakayama, H.2    Reith, J.3
  • 27
    • 6344292389 scopus 로고    scopus 로고
    • Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species
    • Zou M.H., S.S. Kirkpatrick, B.J. Davis, and et al. Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species J Biol Chem 279 2004 43940 43951
    • (2004) J Biol Chem , vol.279 , pp. 43940-43951
    • Zou, M.H.1    Kirkpatrick, S.S.2    Davis, B.J.3
  • 28
    • 0036095269 scopus 로고    scopus 로고
    • Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation
    • Y. Ido, D. Carling, and N. Ruderman Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation Diabetes 51 2002 159 167
    • (2002) Diabetes , vol.51 , pp. 159-167
    • Ido, Y.1    Carling, D.2    Ruderman, N.3
  • 29
    • 33646105593 scopus 로고    scopus 로고
    • Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells
    • K. Isoda, J.L. Young, A. Zirlik, and et al. Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells Arterioscler Thromb Vasc Biol 26 2006 611 617
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 611-617
    • Isoda, K.1    Young, J.L.2    Zirlik, A.3
  • 30
    • 33644749330 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
    • D. Kukidome, T. Nishikawa, K. Sonoda, and et al. Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells Diabetes 55 2006 120 127
    • (2006) Diabetes , vol.55 , pp. 120-127
    • Kukidome, D.1    Nishikawa, T.2    Sonoda, K.3
  • 31
    • 18044393806 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle
    • N. Ouchi, R. Shibata, and K. Walsh AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle Circ Res 96 2005 838 846
    • (2005) Circ Res , vol.96 , pp. 838-846
    • Ouchi, N.1    Shibata, R.2    Walsh, K.3
  • 32
    • 19444380162 scopus 로고    scopus 로고
    • Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells
    • N. Ouslimani, J. Peynet, D. Bonnefont-Rousselot, and et al. Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells Metabolism 54 2005 829 834
    • (2005) Metabolism , vol.54 , pp. 829-834
    • Ouslimani, N.1    Peynet, J.2    Bonnefont-Rousselot, D.3
  • 33
    • 33846786408 scopus 로고    scopus 로고
    • Metformin reduces endothelial cell expression of both the receptor for advanced glycation end products and lectin-like oxidized receptor 1
    • N. Ouslimani, M. Mahrouf, J. Peynet, and et al. Metformin reduces endothelial cell expression of both the receptor for advanced glycation end products and lectin-like oxidized receptor 1 Metabolism 56 2007 308 313
    • (2007) Metabolism , vol.56 , pp. 308-313
    • Ouslimani, N.1    Mahrouf, M.2    Peynet, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.