Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)

Biological Research for Nursing

Volumn 18, Issue 2, 2016, Pages 193-198

  Heitkemper, Margaret M ^a   Han, Claire Jungyoun ^a   Jarrett, Monica E ^a   Gu, Haiwei ^a   Djukovic, Danijel ^a   Shulman, Robert J ^b   Raftery, Daniel ^a,c   Henderson, Wendy A ^d   Cain, Kevin C ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d NATIONAL INSTITUTE OF NURSING RESEARCH   (United States)

Author keywords

irritable bowel syndrome; melatonin; metabolomics; sleep; tryptophan

Indexed keywords

BIOLOGICAL MARKER; HYDROCORTISONE; TRYPTOPHAN;

ADOLESCENT; ADULT; BLOOD; COMPARATIVE STUDY; FEMALE; HUMAN; IRRITABLE COLON; MENTAL STRESS; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PILOT STUDY; POLYSOMNOGRAPHY; SLEEP; SLEEP DISORDER; YOUNG ADULT;

ADOLESCENT; ADULT; BIOMARKERS; FEMALE; HUMANS; HYDROCORTISONE; IRRITABLE BOWEL SYNDROME; MIDDLE AGED; PILOT PROJECTS; POLYSOMNOGRAPHY; SLEEP; SLEEP WAKE DISORDERS; STRESS, PSYCHOLOGICAL; TRYPTOPHAN; YOUNG ADULT;

EID: 84959349331     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800415594251     Document Type: Article

References (17)

1. L.AspM.HoltzeS.B.PowellH.KarlssonS.Erhardt (2010). Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice. International Journal of Neuropsychopharmacology, 13, 475–485. doi:10.1017/s1461145709990253
2. A.A.Badawy (2013). Tryptophan: The key to boosting brain serotonin synthesis in depressive illness. Journal of Psychopharmacology, 27, 878–893. doi:10.1177/0269881113499209
3. G.ClarkeP.FitzgeraldJ.F.CryanE.M.CassidyE.M.QuigleyT.G.Dinan (2009). Tryptophan degradation in irritable bowel syndrome: Evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterology, 9, 6. doi:10.1186/1471-230x-9-6-
4. L.M.DelRossoA.L.ChessonR.Hoque (2014). Manual characterization of sleep spindle index in patients with narcolepsy and idiopathic hypersomnia. Sleep Disorders, 2014, 1–4. doi:10.1155/2014/271802
5. D.DrossmanE.CorazziariM.DelvauxR.SpillerN.TalleyW.ThompsonW.E.Whitehead (2006). Rome III: The functional gastrointestinal disorders (3rd ed.). McLean, VA: Degnon Associates, Inc.
6. P.FitzgeraldM.Cassidy EugeneG.ClarkeP.ScullyS.BarryM.M.Quigley Eamonn…G.Dinan Timothy (2008). Tryptophan catabolism in females with irritable bowel syndrome: Relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity. Neurogastroenterology and Motility, 20, 1291–1297. doi:10.1111/j.1365-2982.2008.01195.x
7. K.Fukuda (2014). Etiological classification of depression based on the enzymes of tryptophan metabolism. BMC Psychiatry, 14, 8. doi:10.1186/s12888-014-0372-y
8. M.M.HeitkemperK.C.CainW.DeechakawanA.PoppeS.E.JunR.L.BurrM.E.Jarrett (2012). Anticipation of public speaking and sleep and the hypothalamic-pituitary-adrenal axis in women with irritable bowel syndrome. Neurogastroenterology and Motility, 24, 626–631, e270–e271. doi:10.1111/j.1365-2982.2012.01915.x
9. A.IcenhourJ.LanghorstS.BensonM.SchlamannS.HampelH.Engler…S.Elsenbruch (2015). Neural circuitry of abdominal pain-related fear learning and reinstatement in irritable bowel syndrome. Neurogastroenterology and Motility, 27, 114–127. doi:10.1111/nmo.12489
10. M.JarrettM.HeitkemperK.C.CainR.L.BurrV.Hertig (2000). Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. Digestive Diseases and Sciences, 45, 952–959.
11. P.J.KennedyA.P.AllenA.O’NeillE.M.QuigleyJ.F.CryanT.G.DinanG.Clarke (2014). Acute tryptophan depletion reduces kynurenine levels: Implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome. Psychopharmacology, 232, 1357–1371. doi:10.1007/s00213-014-3767-z
12. J.M.LacknerJ.JaccardC.Baum (2013). Multidomain patient-reported outcomes of irritable bowel syndrome: Exploring person-centered perspectives to better understand symptom severity scores. Value in Health, 16, 97–103. doi:10.1016/j.jval.2012.08.2207
13. S.M.O’MahonyG.ClarkeY.E.BorreT.G.DinanJ.F.Cryan (2015). Serotonin, tryptophan metabolism and the brain-gut-microbiome axis. Behavioural Brain Research, 277C, 32–48. doi:10.1016/j.bbr.2014.07.027
14. J.SavitzW.C.DrevetsC.M.SmithT.A.VictorB.E.WurfelP.S.Bellgowan…R.Dantzer (2015). Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder. Neuropsychopharmacology, 40, 463–471. doi:10.1038/npp.2014.194
15. K.T.H.SiahR.K.M.WongK.Y.Ho (2014). Melatonin for the treatment of irritable bowel syndrome. World Journal of Gastroenterology, 20, 2492. doi:10.3748/wjg.v20.i10.2492
16. L.ZhangJ.T.GongH.Q.ZhangQ.H.SongG.H.XuL.Cai…H.W.Zhang (2015). Melatonin attenuates noise stress-induced gastrointestinal motility disorder and gastric stress ulcer: Role of gastrointestinal hormones and oxidative stress. Journal of Neurogastroenterology and Motility, 21, 189–199. doi:10.5056/jnm14119
17. J.ZhuD.DjukovicL.DengH.GuF.HimmatiE.G.ChioreanD.Raftery (2014). Colorectal cancer detection using targeted serum metabolic profiling. Journal of Proteome Research, 13, 4120–4130.