-
1
-
-
84927150740
-
Immune checkpoint blockade in cancer therapy
-
Postow M.A., Callahan M.K., Wolchok J.D. Immune checkpoint blockade in cancer therapy. J Clin Oncol 2015, 33(17):1974-1982.
-
(2015)
J Clin Oncol
, vol.33
, Issue.17
, pp. 1974-1982
-
-
Postow, M.A.1
Callahan, M.K.2
Wolchok, J.D.3
-
2
-
-
84944472689
-
Releasing the brakes on cancer immunotherapy
-
Ribas A. Releasing the brakes on cancer immunotherapy. N Engl J Med 2015, 373(16):1490-1492.
-
(2015)
N Engl J Med
, vol.373
, Issue.16
, pp. 1490-1492
-
-
Ribas, A.1
-
3
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi F.S., O'Day S.J., McDermott D.F., Weber R.W., Sosman J.A., Haanen J.B., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010, 363(8):711-723.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
4
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C., Long G.V., Brady B., Dutriaux C., Maio M., Mortier L., et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med 2015, 372(4):320-330.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
Dutriaux, C.4
Maio, M.5
Mortier, L.6
-
5
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J., Reckamp K.L., Baas P., Crino L., Eberhardt W.E., Poddubskaya E., et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 2015, 373(2):123-135.
-
(2015)
N Engl J Med
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
-
6
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh P.C., Harview C.L., Yearley J.H., Shintaku I.P., Taylor E.J., Robert L., et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014, 515(7528):568-571.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
7
-
-
85026925656
-
-
Yervoy (ipilimumab) prescribing information
-
Yervoy (ipilimumab) prescribing information. <>. http://packageinserts.bms.com/pi/pi_yervoy.pdf.
-
-
-
-
8
-
-
85026931652
-
-
Nivolumab (Opdivo) prescribing information.
-
Nivolumab (Opdivo) prescribing information. <>. http://packageinserts.bms.com/pi/pi_opdivo.pdf.
-
-
-
-
9
-
-
85026929877
-
-
Pembrolizumab (Keytruda) prescribing information.
-
Pembrolizumab (Keytruda) prescribing information. <>. http://www.merck.com/product/usa/pi_circulars/k/keytruda/keytruda_pi.pdf.
-
-
-
-
10
-
-
84926418972
-
Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: an open-label, single-arm, phase 2 study
-
Calabro L., Morra A., Fonsatti E., Cutaia O., Fazio C., Annesi D., et al. Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: an open-label, single-arm, phase 2 study. Lancet Respir Med 2015, 3(4):301-309.
-
(2015)
Lancet Respir Med
, vol.3
, Issue.4
, pp. 301-309
-
-
Calabro, L.1
Morra, A.2
Fonsatti, E.3
Cutaia, O.4
Fazio, C.5
Annesi, D.6
-
12
-
-
58149335347
-
Immunity, autoimmunity and autoimmune diseases in older people
-
Rosato E., Salsano F. Immunity, autoimmunity and autoimmune diseases in older people. J Biol Regul Homeostat Agents 2008, 22(4):217-224.
-
(2008)
J Biol Regul Homeostat Agents
, vol.22
, Issue.4
, pp. 217-224
-
-
Rosato, E.1
Salsano, F.2
-
14
-
-
84893137826
-
Optimization of immunotherapy in elderly cancer patients
-
Tomihara K., Curiel T.J., Zhang B. Optimization of immunotherapy in elderly cancer patients. Crit Rev Oncogol 2013, 18(6):573-583.
-
(2013)
Crit Rev Oncogol
, vol.18
, Issue.6
, pp. 573-583
-
-
Tomihara, K.1
Curiel, T.J.2
Zhang, B.3
-
15
-
-
84959439434
-
Immune checkpoint protein expression is up-regulated in tumor-bearing elderly mice
-
April 18-22; Philadelphia, PA
-
Lim SJ, Kim JM, Lee WS, Kwon WS, Kim TS, Park KH, et al. Immune checkpoint protein expression is up-regulated in tumor-bearing elderly mice. In: Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA [abstr 4055].
-
(2015)
Proceedings: AACR 106th Annual Meeting 2015
-
-
Lim, S.J.1
Kim, J.M.2
Lee, W.S.3
Kwon, W.S.4
Kim, T.S.5
Park, K.H.6
-
16
-
-
84890501668
-
The immune system and aging: a review
-
Castelo-Branco C., Soveral I. The immune system and aging: a review. Gynecol Endocrinol 2014, 30(1):16-22.
-
(2014)
Gynecol Endocrinol
, vol.30
, Issue.1
, pp. 16-22
-
-
Castelo-Branco, C.1
Soveral, I.2
-
17
-
-
84925548115
-
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
-
Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009, 62(10):1006-1012.
-
(2009)
J Clin Epidemiol
, vol.62
, Issue.10
, pp. 1006-1012
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
18
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: is blinding necessary?
-
Jadad A.R., Moore R.A., Carroll D., Jenkinson C., Reynolds D.J., Gavaghan D.J., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials 1996, 17(1):1-12.
-
(1996)
Control Clin Trials
, vol.17
, Issue.1
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
Jenkinson, C.4
Reynolds, D.J.5
Gavaghan, D.J.6
-
19
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins J.P., Thompson S.G., Deeks J.J., Altman D.G. Measuring inconsistency in meta-analyses. BMJ 2003, 327(7414):557-560.
-
(2003)
BMJ
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
20
-
-
0022992740
-
Meta-analysis in clinical trials
-
DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7(3):177-188.
-
(1986)
Control Clin Trials
, vol.7
, Issue.3
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
21
-
-
0028659004
-
Operating characteristics of a rank correlation test for publication bias
-
Begg C.B., Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50(4):1088-1101.
-
(1994)
Biometrics
, vol.50
, Issue.4
, pp. 1088-1101
-
-
Begg, C.B.1
Mazumdar, M.2
-
22
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M., Davey Smith G., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315(7109):629-634.
-
(1997)
BMJ
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
23
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C., Thomas L., Bondarenko I., O'Day S., Weber J., Garbe C., et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011, 364(26):2517-2526.
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
-
24
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas A., Kefford R., Marshall M.A., Punt C.J., Haanen J.B., Marmol M., et al. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol 2013, 31(5):616-622.
-
(2013)
J Clin Oncol
, vol.31
, Issue.5
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
-
25
-
-
84901641673
-
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
-
Kwon E.D., Drake C.G., Scher H.I., Fizazi K., Bossi A., van den Eertwegh A.J., et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncol 2014, 15(7):700-712.
-
(2014)
Lancet Oncol
, vol.15
, Issue.7
, pp. 700-712
-
-
Kwon, E.D.1
Drake, C.G.2
Scher, H.I.3
Fizazi, K.4
Bossi, A.5
van den Eertwegh, A.J.6
-
26
-
-
84938205998
-
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial
-
Ribas A., Puzanov I., Dummer R., Schadendorf D., Hamid O., Robert C., et al. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncol 2015, 16(8):908-918.
-
(2015)
Lancet Oncol
, vol.16
, Issue.8
, pp. 908-918
-
-
Ribas, A.1
Puzanov, I.2
Dummer, R.3
Schadendorf, D.4
Hamid, O.5
Robert, C.6
-
27
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H., Paz-Ares L., Horn L., Spigel D.R., Steins M., Ready N.E., et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med 2015.
-
(2015)
N Engl J Med
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
Spigel, D.R.4
Steins, M.5
Ready, N.E.6
-
28
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer R.J., Escudier B., McDermott D.F., George S., Hammers H.J., Srinivas S., et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med 2015.
-
(2015)
N Engl J Med
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
George, S.4
Hammers, H.J.5
Srinivas, S.6
-
29
-
-
84941789707
-
Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients
-
Sa S., Qian W., Ellis S., Mason E., Khattak M.A., Gupta A., et al. Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients. Melanoma Res 2015, 25(5):432-442.
-
(2015)
Melanoma Res
, vol.25
, Issue.5
, pp. 432-442
-
-
Sa, S.1
Qian, W.2
Ellis, S.3
Mason, E.4
Khattak, M.A.5
Gupta, A.6
-
30
-
-
84916881425
-
Ipilimumab for advanced melanoma: experience from the spanish expanded access program
-
Berrocal A., Arance A., Lopez Martin J.A., Soriano V., Munoz E., Alonso L., et al. Ipilimumab for advanced melanoma: experience from the spanish expanded access program. Melanoma Res 2014, 24(6):577-583.
-
(2014)
Melanoma Res
, vol.24
, Issue.6
, pp. 577-583
-
-
Berrocal, A.1
Arance, A.2
Lopez Martin, J.A.3
Soriano, V.4
Munoz, E.5
Alonso, L.6
-
31
-
-
84901246811
-
Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohort
-
Ascierto P.A., Simeone E., Sileni V.C., Pigozzo J., Maio M., Altomonte M., et al. Clinical experience with ipilimumab 3 mg/kg: real-world efficacy and safety data from an expanded access programme cohort. J Transl Med 2014, 12:116.
-
(2014)
J Transl Med
, vol.12
, pp. 116
-
-
Ascierto, P.A.1
Simeone, E.2
Sileni, V.C.3
Pigozzo, J.4
Maio, M.5
Altomonte, M.6
-
32
-
-
84899543113
-
Efficacy and safety of ipilimumab in elderly patients with pretreated advanced melanoma treated at Italian centres through the expanded access programme
-
Chiarion Sileni V., Pigozzo J., Ascierto P.A., Grimaldi A.M., Maio M., Di Guardo L., et al. Efficacy and safety of ipilimumab in elderly patients with pretreated advanced melanoma treated at Italian centres through the expanded access programme. J Exp Clin Cancer Res 2014, 33:30.
-
(2014)
J Exp Clin Cancer Res
, vol.33
, pp. 30
-
-
Chiarion Sileni, V.1
Pigozzo, J.2
Ascierto, P.A.3
Grimaldi, A.M.4
Maio, M.5
Di Guardo, L.6
-
33
-
-
77955720671
-
Tracing thymic output in older individuals
-
Mitchell W.A., Lang P.O., Aspinall R. Tracing thymic output in older individuals. Clin Exp Immunol 2010, 161(3):497-503.
-
(2010)
Clin Exp Immunol
, vol.161
, Issue.3
, pp. 497-503
-
-
Mitchell, W.A.1
Lang, P.O.2
Aspinall, R.3
-
34
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor K., Li G., Vallejo A.N., Lee W.W., Koetz K., Bryl E., et al. The influence of age on T cell generation and TCR diversity. J Immunol 2005, 174(11):7446-7452.
-
(2005)
J Immunol
, vol.174
, Issue.11
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
Lee, W.W.4
Koetz, K.5
Bryl, E.6
-
35
-
-
0020500246
-
The immune response of aged mice to influenza: diminished T-cell proliferation, interleukin 2 production and cytotoxicity
-
Effros R.B., Walford R.L. The immune response of aged mice to influenza: diminished T-cell proliferation, interleukin 2 production and cytotoxicity. Cell Immunol 1983, 81(2):298-305.
-
(1983)
Cell Immunol
, vol.81
, Issue.2
, pp. 298-305
-
-
Effros, R.B.1
Walford, R.L.2
-
36
-
-
0025290641
-
Polymorphism of age-related changes in interleukin (IL) production: differential changes of T helper subpopulations, synthesizing IL 2, IL 3 and IL 4
-
Kubo M., Cinader B. Polymorphism of age-related changes in interleukin (IL) production: differential changes of T helper subpopulations, synthesizing IL 2, IL 3 and IL 4. Eur J Immunol 1990, 20(6):1289-1296.
-
(1990)
Eur J Immunol
, vol.20
, Issue.6
, pp. 1289-1296
-
-
Kubo, M.1
Cinader, B.2
-
37
-
-
0025086403
-
Age-related decrement in cytotoxic T lymphocyte (CTL) activity is associated with decreased levels of mRNA encoded by two CTL-associated serine esterase genes and the perforin gene in mice
-
Bloom E.T., Umehara H., Bleackley R.C., Okumura K., Mostowski H., Babbitt J.T. Age-related decrement in cytotoxic T lymphocyte (CTL) activity is associated with decreased levels of mRNA encoded by two CTL-associated serine esterase genes and the perforin gene in mice. Eur J Immunol 1990, 20(10):2309-2316.
-
(1990)
Eur J Immunol
, vol.20
, Issue.10
, pp. 2309-2316
-
-
Bloom, E.T.1
Umehara, H.2
Bleackley, R.C.3
Okumura, K.4
Mostowski, H.5
Babbitt, J.T.6
-
38
-
-
33845408098
-
High accumulation of T regulatory cells prevents the activation of immune responses in aged animals
-
Sharma S., Dominguez A.L., Lustgarten J. High accumulation of T regulatory cells prevents the activation of immune responses in aged animals. J Immunol 2006, 177(12):8348-8355.
-
(2006)
J Immunol
, vol.177
, Issue.12
, pp. 8348-8355
-
-
Sharma, S.1
Dominguez, A.L.2
Lustgarten, J.3
-
39
-
-
37349003404
-
Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice
-
Grizzle W.E., Xu X., Zhang S., Stockard C.R., Liu C., Yu S., et al. Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice. Mech Ageing Dev 2007, 128(11-12):672-680.
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.11-12
, pp. 672-680
-
-
Grizzle, W.E.1
Xu, X.2
Zhang, S.3
Stockard, C.R.4
Liu, C.5
Yu, S.6
-
40
-
-
84860181087
-
Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice
-
Hurez V., Daniel B.J., Sun L., Liu A.J., Ludwig S.M., Kious M.J., et al. Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice. Cancer Res 2012, 72(8):2089-2099.
-
(2012)
Cancer Res
, vol.72
, Issue.8
, pp. 2089-2099
-
-
Hurez, V.1
Daniel, B.J.2
Sun, L.3
Liu, A.J.4
Ludwig, S.M.5
Kious, M.J.6
|