메뉴 건너뛰기




Volumn 11, Issue 2, 2016, Pages 141-148

Induced pluripotent stem cell-derived mesenchymal stem/stromal cells: A leap toward personalized therapies for cancer

Author keywords

Cancer; Cell therapy; IPSCs; MSCs; Precision medicine

Indexed keywords

F ACTIN; KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; PLATELET DERIVED GROWTH FACTOR; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN; WNT3A PROTEIN;

EID: 84959342180     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1574888X10666151001114321     Document Type: Review
Times cited : (7)

References (69)
  • 1
    • 0016174481 scopus 로고
    • The effect of cells transferred into the mouse blastocyst on subsequent development
    • Brinster RL. The effect of cells transferred into the mouse blastocyst on subsequent development. J Exp Med 1974; 140(4): 1049-56.
    • (1974) J Exp Med , vol.140 , Issue.4 , pp. 1049-1056
    • Brinster, R.L.1
  • 2
    • 84870297256 scopus 로고    scopus 로고
    • Insights into bone marrow-derived mesenchymal stem cells safety for cutaneous repair and regeneration
    • Wu Y, Huang S, Enhe J, Fu X. Insights into bone marrow-derived mesenchymal stem cells safety for cutaneous repair and regeneration. Int Wound J 2012; 9(6): 586-94.
    • (2012) Int Wound J , vol.9 , Issue.6 , pp. 586-594
    • Wu, Y.1    Huang, S.2    Enhe, J.3    Fu, X.4
  • 3
    • 84878753775 scopus 로고    scopus 로고
    • Adipose tissue-derived multipotent stromal cells have a higher immunomodulatory capacity than their bone marrow-derived counterparts
    • Melief SM, Zwaginga JJ, Fibbe WE, Roelofs H. Adipose tissue-derived multipotent stromal cells have a higher immunomodulatory capacity than their bone marrow-derived counterparts. Stem Cells Transl Med 2013; 2(6): 455-63.
    • (2013) Stem Cells Transl Med , vol.2 , Issue.6 , pp. 455-463
    • Melief, S.M.1    Zwaginga, J.J.2    Fibbe, W.E.3    Roelofs, H.4
  • 6
    • 79952899995 scopus 로고    scopus 로고
    • Methods for making induced pluripotent stem cells: Reprogramming a la carte
    • Gonzalez F, Boue S, Izpisua Belmonte JC. Methods for making induced pluripotent stem cells: reprogramming a la carte. Nat Rev Genet 2011; 12(4): 231-42.
    • (2011) Nat Rev Genet , vol.12 , Issue.4 , pp. 231-242
    • Gonzalez, F.1    Boue, S.2    Izpisua Belmonte, J.C.3
  • 7
    • 38949186562 scopus 로고    scopus 로고
    • Mesenchymal stem cell preparations—comparing apples and oranges
    • Wagner W, Ho AD. Mesenchymal stem cell preparations—comparing apples and oranges. Stem Cell Rev 2007; 3(4): 239-48.
    • (2007) Stem Cell Rev , vol.3 , Issue.4 , pp. 239-248
    • Wagner, W.1    Ho, A.D.2
  • 8
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126(4): 663-76.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 9
    • 30544438742 scopus 로고    scopus 로고
    • Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture
    • Wang Y, Huso DL, Harrington J, et al. Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture. Cytotherapy 2005; 7(6): 509-19.
    • (2005) Cytotherapy , vol.7 , Issue.6 , pp. 509-519
    • Wang, Y.1    Huso, D.L.2    Harrington, J.3
  • 10
    • 68249094138 scopus 로고    scopus 로고
    • Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells
    • Nelson TJ, Martinez-Fernandez A, Yamada S, Perez-Terzic C, Ikeda Y, Terzic A. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 2009; 120(5): 408-16.
    • (2009) Circulation , vol.120 , Issue.5 , pp. 408-416
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Yamada, S.3    Perez-Terzic, C.4    Ikeda, Y.5    Terzic, A.6
  • 11
    • 77949350004 scopus 로고    scopus 로고
    • Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
    • Lian Q, Zhang Y, Zhang J, et al. Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation 2010; 121(9): 1113-23.
    • (2010) Circulation , vol.121 , Issue.9 , pp. 1113-1123
    • Lian, Q.1    Zhang, Y.2    Zhang, J.3
  • 12
    • 67349108858 scopus 로고    scopus 로고
    • Teratoma formation by human embryonic stem cells: Evaluation of essential parameters for future safety studies
    • Hentze H, Soong PL, Wang ST, Phillips BW, Putti TC, Dunn NR. Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies. Stem Cell Res 2009; 2(3): 198-210.
    • (2009) Stem Cell Res , vol.2 , Issue.3 , pp. 198-210
    • Hentze, H.1    Soong, P.L.2    Wang, S.T.3    Phillips, B.W.4    Putti, T.C.5    Dunn, N.R.6
  • 14
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85(8): 348-62.
    • (2009) Proc Jpn Acad Ser B Phys Biol Sci , vol.85 , Issue.8 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3    Saeki, K.4    Hasegawa, M.5
  • 15
    • 84868154075 scopus 로고    scopus 로고
    • Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression
    • Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nat Protoc 2012; 7(11): 2013-21.
    • (2012) Nat Protoc , vol.7 , Issue.11 , pp. 2013-2021
    • Dowey, S.N.1    Huang, X.2    Chou, B.K.3    Ye, Z.4    Cheng, L.5
  • 16
    • 34447510789 scopus 로고    scopus 로고
    • Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma
    • Stoff-Khalili MA, Rivera AA, Mathis JM, et al. Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma. Breast Cancer Res Treat 2007; 105(2): 157-67.
    • (2007) Breast Cancer Res Treat , vol.105 , Issue.2 , pp. 157-167
    • Stoff-Khalili, M.A.1    Rivera, A.A.2    Mathis, J.M.3
  • 17
    • 43049095411 scopus 로고    scopus 로고
    • Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma
    • Sonabend AM, Ulasov IV, Tyler MA, Rivera AA, Mathis JM, Lesniak MS. Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma. Stem Cells 2008; 26(3): 831-41.
    • (2008) Stem Cells , vol.26 , Issue.3 , pp. 831-841
    • Sonabend, A.M.1    Ulasov, I.V.2    Tyler, M.A.3    Rivera, A.A.4    Mathis, J.M.5    Lesniak, M.S.6
  • 18
    • 33645468259 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses
    • Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L. Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses. Mol Cancer Ther 2006; 5(3): 755-66.
    • (2006) Mol Cancer Ther , vol.5 , Issue.3 , pp. 755-766
    • Komarova, S.1    Kawakami, Y.2    Stoff-Khalili, M.A.3    Curiel, D.T.4    Pereboeva, L.5
  • 19
    • 33847612451 scopus 로고    scopus 로고
    • Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells
    • Ozaki Y, Nishimura M, Sekiya K, et al. Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells. Stem Cells Dev 2007; 16(1): 119-29.
    • (2007) Stem Cells Dev , vol.16 , Issue.1 , pp. 119-129
    • Ozaki, Y.1    Nishimura, M.2    Sekiya, K.3
  • 20
    • 77953716959 scopus 로고    scopus 로고
    • Treatment of metastatic neuroblastoma with systemic oncolytic virotherapy delivered by autologous mesenchymal stem cells: An exploratory study
    • Garcia-Castro J, Alemany R, Cascallo M, et al. Treatment of metastatic neuroblastoma with systemic oncolytic virotherapy delivered by autologous mesenchymal stem cells: an exploratory study. Cancer Gene Ther 2010; 17(7): 476-83.
    • (2010) Cancer Gene Ther , vol.17 , Issue.7 , pp. 476-483
    • Garcia-Castro, J.1    Alemany, R.2    Cascallo, M.3
  • 21
    • 84916897010 scopus 로고    scopus 로고
    • Mesenchymal stem cell-based NK4 gene therapy in nude mice bearing gastric cancer xenografts
    • Zhu Y, Cheng M, Yang Z, et al. Mesenchymal stem cell-based NK4 gene therapy in nude mice bearing gastric cancer xenografts. Drug Des Devel Ther 2014; 8: 2449-62.
    • (2014) Drug Des Devel Ther , vol.8 , pp. 2449-2462
    • Zhu, Y.1    Cheng, M.2    Yang, Z.3
  • 22
    • 79951841819 scopus 로고    scopus 로고
    • Concise review: Dissecting a discrepancy in the literature: Do mesenchymal stem cells support or suppress tumor growth?
    • Klopp AH, Gupta A, Spaeth E, Andreeff M, Marini F, 3rd. Concise review: Dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth? Stem Cells 2011; 29(1): 11-9.
    • (2011) Stem Cells , vol.29 , Issue.1 , pp. 11-19
    • Klopp, A.H.1    Gupta, A.2    Spaeth, E.3    Reeff, M.4    Marini, F.5
  • 23
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C, et al. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003; 102(10): 3837-44.
    • (2003) Blood , vol.102 , Issue.10 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3
  • 24
    • 84925507571 scopus 로고    scopus 로고
    • Conditioned medium from mesenchymal stem cells enhances the migration of hepatoma cells through CXCR4 up-regulation and F-actin remodeling
    • Li X, Luo Q, Sun J, Song G. Conditioned medium from mesenchymal stem cells enhances the migration of hepatoma cells through CXCR4 up-regulation and F-actin remodeling. Biotechnol Lett 2014 37(3): 511-21.
    • (2014) Biotechnol Lett , vol.37 , Issue.3 , pp. 511-521
    • Li, X.1    Luo, Q.2    Sun, J.3    Song, G.4
  • 25
    • 44849121129 scopus 로고    scopus 로고
    • Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing
    • Chen L, Tredget EE, Wu PY, Wu Y. Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS One 2008; 3(4): e1886.
    • (2008) Plos One , vol.3 , Issue.4
    • Chen, L.1    Tredget, E.E.2    Wu, P.Y.3    Wu, Y.4
  • 26
    • 70449716971 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce dermal fibroblast responses to injury
    • Smith AN, Willis E, Chan VT, et al. Mesenchymal stem cells induce dermal fibroblast responses to injury. Exp Cell Res 2010; 316(1): 48-54.
    • (2010) Exp Cell Res , vol.316 , Issue.1 , pp. 48-54
    • Smith, A.N.1    Willis, E.2    Chan, V.T.3
  • 27
    • 35348831024 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis
    • Wu Y, Chen L, Scott PG, Tredget EE. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 2007; 25(10): 2648-59.
    • (2007) Stem Cells , vol.25 , Issue.10 , pp. 2648-2659
    • Wu, Y.1    Chen, L.2    Scott, P.G.3    Tredget, E.E.4
  • 28
    • 84859811743 scopus 로고    scopus 로고
    • Towards whole-body imaging at the single cell level using ultra-sensitive stem cell labeling with oligo-arginine modified upconversion nanoparticles
    • Wang C, Cheng L, Xu H, Liu Z. Towards whole-body imaging at the single cell level using ultra-sensitive stem cell labeling with oligo-arginine modified upconversion nanoparticles. Biomaterials 2012; 33(19): 4872-81.
    • (2012) Biomaterials , vol.33 , Issue.19 , pp. 4872-4881
    • Wang, C.1    Cheng, L.2    Xu, H.3    Liu, Z.4
  • 29
    • 0035144015 scopus 로고    scopus 로고
    • Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion
    • Devine SM, Bartholomew AM, Mahmud N, et al. Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion. Exp Hematol 2001; 29(2): 244-55.
    • (2001) Exp Hematol , vol.29 , Issue.2 , pp. 244-255
    • Devine, S.M.1    Bartholomew, A.M.2    Mahmud, N.3
  • 30
    • 77949350004 scopus 로고    scopus 로고
    • Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
    • Lian Q, Zhang Y, Zhang J, et al. Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation 2010; 121(9): 1113-23.
    • (2010) Circulation , vol.121 , Issue.9 , pp. 1113-1123
    • Lian, Q.1    Zhang, Y.2    Zhang, J.3
  • 31
    • 84904107750 scopus 로고    scopus 로고
    • Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow- derived mesenchymal stromal cells from the same donor
    • Diederichs S, Tuan RS. Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow- derived mesenchymal stromal cells from the same donor. Stem Cells Dev 2014; 23(14): 1594-610.
    • (2014) Stem Cells Dev , vol.23 , Issue.14 , pp. 1594-1610
    • Diederichs, S.1    Tuan, R.S.2
  • 32
    • 84857485529 scopus 로고    scopus 로고
    • Differentiation efficiency of induced pluripotent stem cells depends on the number of reprogramming factors
    • Lohle M, Hermann A, Glass H, et al. Differentiation efficiency of induced pluripotent stem cells depends on the number of reprogramming factors. Stem Cells 2012; 30(3): 570-9.
    • (2012) Stem Cells , vol.30 , Issue.3 , pp. 570-579
    • Lohle, M.1    Hermann, A.2    Glass, H.3
  • 33
    • 34548017177 scopus 로고    scopus 로고
    • Wound healing effect of adipose-derived stem cells: A critical role of secretory factors on human dermal fibroblasts
    • Kim WS, Park BS, Sung JH, et al. Wound healing effect of adipose-derived stem cells: a critical role of secretory factors on human dermal fibroblasts. J Dermatol Sci 2007; 48(1): 15-24.
    • (2007) J Dermatol Sci , vol.48 , Issue.1 , pp. 15-24
    • Kim, W.S.1    Park, B.S.2    Sung, J.H.3
  • 34
    • 84908046151 scopus 로고    scopus 로고
    • Multiple paracrine factors secreted by mesenchymal stem cells contribute to angiogenesis
    • Kwon HM, Hur SM, Park KY, et al. Multiple paracrine factors secreted by mesenchymal stem cells contribute to angiogenesis. Vascul Pharmacol 2014; 63(1): 19-28.
    • (2014) Vascul Pharmacol , vol.63 , Issue.1 , pp. 19-28
    • Kwon, H.M.1    Hur, S.M.2    Park, K.Y.3
  • 35
    • 84908674065 scopus 로고    scopus 로고
    • Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow- derived stromal cells in vitro
    • Schnabel LV, Abratte CM, Schimenti JC, et al. Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow- derived stromal cells in vitro. Regen Med 2014; 9(5): 621-35.
    • (2014) Regen Med , vol.9 , Issue.5 , pp. 621-635
    • Schnabel, L.V.1    Abratte, C.M.2    Schimenti, J.C.3
  • 36
    • 77950628997 scopus 로고    scopus 로고
    • Mesenchymal stem cell-conditioned medium accelerates skin wound healing: An in vitro study of fibroblast and keratinocyte scratch assays
    • Walter MN, Wright KT, Fuller HR, MacNeil S, Johnson WE. Mesenchymal stem cell-conditioned medium accelerates skin wound healing: an in vitro study of fibroblast and keratinocyte scratch assays. Exp Cell Res 2010; 316(7): 1271-81.
    • (2010) Exp Cell Res , vol.316 , Issue.7 , pp. 1271-1281
    • Walter, M.N.1    Wright, K.T.2    Fuller, H.R.3    Macneil, S.4    Johnson, W.E.5
  • 37
    • 84925338126 scopus 로고    scopus 로고
    • Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis
    • Zhang J, Guan J, Niu X, et al. Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis. J Transl Med 2015; 13: 49.
    • (2015) J Transl Med , vol.13 , pp. 49
    • Zhang, J.1    Guan, J.2    Niu, X.3
  • 38
    • 84925338126 scopus 로고    scopus 로고
    • Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis
    • Zhang J, Guan J, Niu X, et al. Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis. J Transl Med 2015; 13(1): 49.
    • (2015) J Transl Med , vol.13 , Issue.1 , pp. 49
    • Zhang, J.1    Guan, J.2    Niu, X.3
  • 39
    • 84977904380 scopus 로고    scopus 로고
    • MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs
    • Zhao Q, Gregory CA, Lee RH, et al. MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs. Proc Natl Acad Sci USA 2014.
    • (2014) Proc Natl Acad Sci USA
    • Zhao, Q.1    Gregory, C.A.2    Lee, R.H.3
  • 40
    • 84884288934 scopus 로고    scopus 로고
    • Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
    • Ran FA, Hsu PD, Lin CY, et al. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 2013; 154(6): 1380-9.
    • (2013) Cell , vol.154 , Issue.6 , pp. 1380-1389
    • Ran, F.A.1    Hsu, P.D.2    Lin, C.Y.3
  • 41
    • 84873733109 scopus 로고    scopus 로고
    • A TALEN genome-editing system for generating human stem cell-based disease models
    • Ding Q, Lee YK, Schaefer EA, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 2013; 12(2): 238-51.
    • (2013) Cell Stem Cell , vol.12 , Issue.2 , pp. 238-251
    • Ding, Q.1    Lee, Y.K.2    Schaefer, E.A.3
  • 42
    • 84906338195 scopus 로고    scopus 로고
    • Treatment of Crohn's disease complicated with myelodysplastic syndrome via allogeneic hematopoietic stem cell transplantation: Case report and literature review
    • Hu C, Lv L, Liu D, Huo J. Treatment of Crohn's disease complicated with myelodysplastic syndrome via allogeneic hematopoietic stem cell transplantation: case report and literature review. Clin J Gastroenterol 2014; 7: 299-304.
    • (2014) Clin J Gastroenterol , vol.7 , pp. 299-304
    • Hu, C.1    Lv, L.2    Liu, D.3    Huo, J.4
  • 43
    • 84919354336 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy
    • Gu F, Wang D, Zhang H, et al. Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy. Clin Rheumatol 2014; 33(11): 1611-9.
    • (2014) Clin Rheumatol , vol.33 , Issue.11 , pp. 1611-1619
    • Gu, F.1    Wang, D.2    Zhang, H.3
  • 44
    • 84860754338 scopus 로고    scopus 로고
    • Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor- tropic properties
    • Yi BR, Kim SU, Kim YB, Lee HJ, Cho MH, Choi KC. Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor- tropic properties. Oncol Rep 2012; 27(6): 1823-8.
    • (2012) Oncol Rep , vol.27 , Issue.6 , pp. 1823-1828
    • Yi, B.R.1    Kim, S.U.2    Kim, Y.B.3    Lee, H.J.4    Cho, M.H.5    Choi, K.C.6
  • 45
    • 84869749821 scopus 로고    scopus 로고
    • Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury
    • Menge T, Zhao Y, Zhao J, et al. Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury. Sci Transl Med 2012; 4(161): 161ra50.
    • (2012) Sci Transl Med , vol.4 , Issue.161
    • Menge, T.1    Zhao, Y.2    Zhao, J.3
  • 46
    • 84864219921 scopus 로고    scopus 로고
    • Antitumor activities of human placenta-derived mesenchymal stem cells expressing endostatin on ovarian cancer
    • Zheng L, Zhang D, Chen X, Yang L, Wei Y, Zhao X. Antitumor activities of human placenta-derived mesenchymal stem cells expressing endostatin on ovarian cancer. PLoS One 2012; 7(7): e39119.
    • (2012) Plos One , vol.7 , Issue.7
    • Zheng, L.1    Zhang, D.2    Chen, X.3    Yang, L.4    Wei, Y.5    Zhao, X.6
  • 47
    • 63849148548 scopus 로고    scopus 로고
    • Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
    • Sasportas LS, Kasmieh R, Wakimoto H, et al. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci USA 2009; 106(12): 4822-7.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.12 , pp. 4822-4827
    • Sasportas, L.S.1    Kasmieh, R.2    Wakimoto, H.3
  • 48
    • 84927631755 scopus 로고    scopus 로고
    • Bone Marrow-Derived Stem Cell Therapy for Metastatic Brain Cancers
    • Kaneko Y, Tajiri N, Staples M, et al. Bone Marrow-Derived Stem Cell Therapy for Metastatic Brain Cancers. Cell Transplant 2015; 24(4): 625-30.
    • (2015) Cell Transplant , vol.24 , Issue.4 , pp. 625-630
    • Kaneko, Y.1    Tajiri, N.2    Staples, M.3
  • 49
    • 84888395554 scopus 로고    scopus 로고
    • Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: Implications for clinical use
    • Metz MZ, Gutova M, Lacey SF, et al. Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use. Stem Cells Transl Med 2013; 2(12): 983-92.
    • (2013) Stem Cells Transl Med , vol.2 , Issue.12 , pp. 983-992
    • Metz, M.Z.1    Gutova, M.2    Lacey, S.F.3
  • 50
    • 33750081777 scopus 로고    scopus 로고
    • FDA regulation of stem-cell-based therapies
    • Halme DG, Kessler DA. FDA regulation of stem-cell-based therapies. N Engl J Med 2006; 355(16): 1730-5.
    • (2006) N Engl J Med , vol.355 , Issue.16 , pp. 1730-1735
    • Halme, D.G.1    Kessler, D.A.2
  • 51
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells. Cell 2008; 134(5): 877-86.
    • (2008) Cell , vol.134 , Issue.5 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3
  • 52
    • 84859108713 scopus 로고    scopus 로고
    • Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma
    • Matsuoka J, Yashiro M, Sakurai K, et al. Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma. J Surg Res 2012; 174(1): 130-5.
    • (2012) J Surg Res , vol.174 , Issue.1 , pp. 130-135
    • Matsuoka, J.1    Yashiro, M.2    Sakurai, K.3
  • 53
    • 48249105531 scopus 로고    scopus 로고
    • Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
    • Chiou SH, Yu CC, Huang CY, et al. Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma. Clin Cancer Res 2008; 14(13): 4085-95.
    • (2008) Clin Cancer Res , vol.14 , Issue.13 , pp. 4085-4095
    • Chiou, S.H.1    Yu, C.C.2    Huang, C.Y.3
  • 54
    • 68949218780 scopus 로고    scopus 로고
    • Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells
    • Saiki Y, Ishimaru S, Mimori K, et al. Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells. Ann Surg Oncol 2009; 16(9): 2638-44.
    • (2009) Ann Surg Oncol , vol.16 , Issue.9 , pp. 2638-2644
    • Saiki, Y.1    Ishimaru, S.2    Mimori, K.3
  • 55
    • 0026630266 scopus 로고
    • APC mutations occur early during colorectal tumorigenesis
    • Powell SM, Zilz N, Beazer-Barclay Y, et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359(6392): 235-7.
    • (1992) Nature , vol.359 , Issue.6392 , pp. 235-237
    • Powell, S.M.1    Zilz, N.2    Beazer-Barclay, Y.3
  • 56
    • 0026726952 scopus 로고
    • Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas
    • Cottrell S, Bicknell D, Kaklamanis L, Bodmer WF. Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet 1992; 340(8820): 626-30.
    • (1992) Lancet , vol.340 , Issue.8820 , pp. 626-630
    • Cottrell, S.1    Bicknell, D.2    Kaklamanis, L.3    Bodmer, W.F.4
  • 57
    • 17344365851 scopus 로고    scopus 로고
    • Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium
    • Ford D, Easton DF, Stratton M, et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am J Hum Genet 1998; 62(3): 676-89.
    • (1998) Am J Hum Genet , vol.62 , Issue.3 , pp. 676-689
    • Ford, D.1    Easton, D.F.2    Stratton, M.3
  • 59
    • 84863124648 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
    • Hamilton A, Helgason GV, Schemionek M, et al. Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival. Blood 2012; 119(6): 1501-10.
    • (2012) Blood , vol.119 , Issue.6 , pp. 1501-1510
    • Hamilton, A.1    Helgason, G.V.2    Schemionek, M.3
  • 60
    • 84866289168 scopus 로고    scopus 로고
    • Regulations and guidelines governing stem cell based products: Clinical considerations
    • George B. Regulations and guidelines governing stem cell based products: Clinical considerations. Perspect Clin Res 2011; 2(3): 94-9.
    • (2011) Perspect Clin Res , vol.2 , Issue.3 , pp. 94-99
    • George, B.1
  • 61
    • 84929832509 scopus 로고    scopus 로고
    • Establishing criteria for human mesenchymal stem cell potency
    • Samsonraj RM, Rai B, Sathiyanathan P, et al. Establishing criteria for human mesenchymal stem cell potency. Stem cells 2015; 33(6): 1878-91.
    • (2015) Stem Cells , vol.33 , Issue.6 , pp. 1878-1891
    • Samsonraj, R.M.1    Rai, B.2    Sathiyanathan, P.3
  • 62
    • 84922568930 scopus 로고    scopus 로고
    • Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications
    • Wuchter P, Bieback K, Schrezenmeier H, et al. Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications. Cytotherapy 2015; 17(2): 128-39.
    • (2015) Cytotherapy , vol.17 , Issue.2 , pp. 128-139
    • Wuchter, P.1    Bieback, K.2    Schrezenmeier, H.3
  • 63
    • 80052749542 scopus 로고    scopus 로고
    • An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells
    • Tang C, Lee AS, Volkmer JP, et al. An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol 2011; 29(9): 829-34.
    • (2011) Nat Biotechnol , vol.29 , Issue.9 , pp. 829-834
    • Tang, C.1    Lee, A.S.2    Volkmer, J.P.3
  • 64
    • 0038700553 scopus 로고    scopus 로고
    • Selective ablation of human embryonic stem cells expressing a "suicide" gene
    • Schuldiner M, Itskovitz-Eldor J, Benvenisty N. Selective ablation of human embryonic stem cells expressing a "suicide" gene. Stem Cells 2003; 21(3): 257-65.
    • (2003) Stem Cells , vol.21 , Issue.3 , pp. 257-265
    • Schuldiner, M.1    Itskovitz-Eldor, J.2    Benvenisty, N.3
  • 65
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009; 458(7239): 771-5.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 66
    • 77953482266 scopus 로고    scopus 로고
    • Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-beta/activin/nodal signaling using SB-431542
    • Mahmood A, Harkness L, Schroder HD, Abdallah BM, Kassem M. Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-beta/activin/nodal signaling using SB-431542. J Bone Miner Res 2010; 25(6): 1216-33.
    • (2010) J Bone Miner Res , vol.25 , Issue.6 , pp. 1216-1233
    • Mahmood, A.1    Harkness, L.2    Schroder, H.D.3    Abdallah, B.M.4    Kassem, M.5
  • 67
    • 84868227016 scopus 로고    scopus 로고
    • Induction of cancerous stem cells during embryonic stem cell differentiation
    • Fujimori H, Shikanai M, Teraoka H, Masutani M, Yoshioka K. Induction of cancerous stem cells during embryonic stem cell differentiation. J Biol Chem 2012; 287(44): 36777-91.
    • (2012) J Biol Chem , vol.287 , Issue.44 , pp. 36777-36791
    • Fujimori, H.1    Shikanai, M.2    Teraoka, H.3    Masutani, M.4    Yoshioka, K.5
  • 68
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010; 467(7313): 285-90.
    • (2010) Nature , vol.467 , Issue.7313 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 69
    • 84926217252 scopus 로고    scopus 로고
    • A single epidermal stem cell strategy for safe ex vivo gene therapy
    • Droz-Georget Lathion S, Rochat A, Knott G, et al. A single epidermal stem cell strategy for safe ex vivo gene therapy. EMBO Mol Med 2015; 7(4): 380-93.
    • (2015) EMBO Mol Med , vol.7 , Issue.4 , pp. 380-393
    • Droz-Georget Lathion, S.1    Rochat, A.2    Knott, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.