ADD ON THERAPY;
AGITATION;
AKATHISIA;
ARTICLE;
BODY WEIGHT DISORDER;
DRUG EFFICACY;
DRUG MECHANISM;
DRUG POTENCY;
DRUG TOLERABILITY;
HUMAN;
INTRINSIC ACTIVITY;
MAJOR DEPRESSION;
PRIORITY JOURNAL;
RECEPTOR BINDING;
SCHIZOPHRENIA;
WEIGHT GAIN;
AGONISTS;
DEPRESSIVE DISORDER, MAJOR;
DRUG EFFECTS;
An index of relative central α-Adrenergic receptor antagonism by antipsychotic medications
Mitzenberg MJ, Yoon JH. An index of relative central α-Adrenergic receptor antagonism by antipsychotic medications. Exp Clin Psychopharmacol. 2011; 19(1): 31-39.
5-HT2A receptor or alpha1-Adrenoceptor activation induces excitatory postsynaptic currents in layer v pyramidal cells of the medial prefrontal cortex
Marek GJ, Aghahanian GK. 5-HT2A receptor or alpha1-Adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex. Eur J Pharmacol. 1999; 367(2-3): 197-206.
Regulation of the release of serotonin in the dorsal raphe nucleus by alpha1 and alpha2 adrenoceptors
Pudovkina OL, Cremers T, Westerink B. Regulation of the release of serotonin in the dorsal raphe nucleus by alpha1 and alpha2 adrenoceptors. Synapse. 2003; 50(1): 77-82.
Stimulation of alpha1-Adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: Reversal by antipsychotic drugs
Amargós-Bosch M, Adell A, Bortolozzi A, Artigas F. Stimulation of alpha1-Adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. J Neurochem. 2003; 87(4): 831-842.
α 1 adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission
Mitrano D, Schroeder JP, Smith Y, et al. α1 adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission. Neuropsychopharmacology. 2012; 37(9): 2161-2172.
Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: Reducing extrapyramidal side effects
Stahl SM. Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal side effects. CNS Spectr. 2013; 18(6): 285-288.
The ABC's of dopamine receptor partial agonists-aripiprazole, brexpiprazole and cariprazine: The 15-min challenge to sort these agents out
Citrome L. The ABC's of dopamine receptor partial agonists-aripiprazole, brexpiprazole and cariprazine: the 15-min challenge to sort these agents out. Int J Clin Pract. 2015; 69(11): 1211-1220.