Oxford Lithium Trial (OxLith) of the early affective, cognitive, neural and biochemical effects of lithium carbonate in bipolar disorder: Study protocol for a randomised controlled trial

Trials

Volumn 17, Issue 1, 2016, Pages

  Saunders, Kate E A ^a   Cipriani, Andrea ^a   Rendell, Jennifer ^a   Attenburrow, Mary Jane ^a   Nelissen, Natalie ^a   Bilderbeck, Amy C ^a   Vasudevan, Sridhar R ^b   Churchill, Grant ^b   Goodwin, Guy M ^a   Nobre, Anna C ^a   Harmer, Catherine J ^a   Harrison, Paul J ^a   Geddes, John R ^a  

^a WARNEFORD HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Bipolar disorder; Experimental medicine; Lithium; Mood instability

Indexed keywords

HYDROCORTISONE; LITHIUM CARBONATE; MELATONIN; PLACEBO; BIOLOGICAL MARKER; TRANQUILIZER;

ADULT; ARTICLE; BIPOLAR DISORDER; BMALL GENE; CIRCADIAN RHYTHM; COGNITION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GAD L1 GENE; GENE; GENE EXPRESSION; GSK3 GENE; HUMAN; IMP GENE; KIDNEY FUNCTION; MAGNETOENCEPHALOGRAPHY; MALE; MENTAL INSTABILITY; PARATHYROID FUNCTION; PER 1 GENE; PER 2 GENE; PHYSICAL ACTIVITY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SLEEP; THYROID FUNCTION; AFFECT; BLOOD; BRAIN; CLINICAL PROTOCOL; DRUG EFFECTS; ENGLAND; GENE EXPRESSION REGULATION; METABOLISM; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; TIME FACTOR; TREATMENT OUTCOME; YOUNG ADULT;

ADULT; AFFECT; ANTIMANIC AGENTS; BIOMARKERS; BIPOLAR DISORDER; BRAIN; CLINICAL PROTOCOLS; COGNITION; DOUBLE-BLIND METHOD; ENGLAND; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LITHIUM CARBONATE; MAGNETIC RESONANCE IMAGING; MAGNETOENCEPHALOGRAPHY; MALE; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; RESEARCH DESIGN; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84959312907     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/s13063-016-1230-7     Document Type: Article

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