Clopidogrel pharmacokinetics and pharmacodynamics in out-of-hospital cardiac arrest patients with acute coronary syndrome undergoing target temperature management

Resuscitation

Volumn 102, Issue , 2016, Pages 63-69

  Kaufmann, Jan ^a   Wellnhofer, Ernst ^a   Stockmann, Helena ^b   Graf, Kristof ^c   Fleck, Eckart ^a   Schroeder, Tim ^b   Stawowy, Philipp ^a   Storm, Christian ^b  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c Judisches Krankenhaus Berlin   (Germany)

Author keywords

Acute coronary syndrome; Clopidogrel metabolism; Hypothermia; Platelet aggregation

Indexed keywords

CLOPIDOGREL; CYTOCHROME P450 2C19; TROPONIN; ANTITHROMBOCYTIC AGENT; TICLOPIDINE;

ACUTE CORONARY SYNDROME; AGED; ANALYTIC METHOD; ARTICLE; BLOOD ANALYSIS; BLOOD CLOTTING PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG METABOLISM; EX VIVO STUDY; FEEDBACK SYSTEM; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIGHT TRANSMITTANCE AGGREGOMETRY; LOADING DRUG DOSE; MALE; MULTIPLE ELECTRODE PLATELET AGGREGOMETRY; OUT OF HOSPITAL CARDIAC ARREST; PHARMACODYNAMICS; PRIORITY JOURNAL; TARGET TEMPERATURE MANAGEMENT; TEMPERATURE DEPENDENCE; THERMOREGULATION; THROMBOCYTE FUNCTION; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; BLOOD; CLINICAL TRIAL; COMPLICATION; FOLLOW UP; INDUCED HYPOTHERMIA; MULTICENTER STUDY; OUT-OF-HOSPITAL CARDIAC ARREST; PROCEDURES; PROSPECTIVE STUDY; RESUSCITATION; TREATMENT OUTCOME;

ACUTE CORONARY SYNDROME; AGED; CARDIOPULMONARY RESUSCITATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPOTHERMIA, INDUCED; MALE; OUT-OF-HOSPITAL CARDIAC ARREST; PLATELET AGGREGATION INHIBITORS; PROSPECTIVE STUDIES; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84959302552     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2016.02.012     Document Type: Article

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