Role of Daphnetin in Rat Severe Acute Pancreatitis Through the Regulation of TLR4/NF-κ B Signaling Pathway Activation

American Journal of Chinese Medicine

Volumn 44, Issue 1, 2016, Pages 149-163

  Liu, Zhiyong ^a,b   Liu, Jiao ^a,b   Zhao, Kailiang ^a   Shi, Qiao ^a   Zuo, Teng ^a   Wang, Guirong ^b   Wang, Weixing ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Daphnetin; Nuclear Factor B; Severe Acute Pancreatitis; Toll like Receptor

Indexed keywords

ALANINE AMINOTRANSFERASE; CREATININE; DAPHNETIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; SUPEROXIDE DISMUTASE; TAUROCHOLIC ACID; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; AUTACOID; CYTOKINE; TLR4 PROTEIN, RAT; UMBELLIFERONE DERIVATIVE;

ACUTE PANCREATITIS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BILIOPANCREATIC DUCT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG STRUCTURE; EDEMA; ENZYME ACTIVITY; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY CELL; MALE; NECROSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PANCREAS DUCT; PANCREATIC TISSUE; PROTEIN EXPRESSION; RAT; RAT MODEL; SEVERE ACUTE PANCREATITIS; SIGNAL TRANSDUCTION; ACUTE DISEASE; ANIMAL; CHEMISTRY; DISEASE MODEL; DRACAENA; DRUG EFFECTS; GENE EXPRESSION; GENETICS; INTRAPERITONEAL DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; METABOLISM; PANCREATITIS; PHYTOTHERAPY; SEVERITY OF ILLNESS INDEX; WISTAR RAT;

ACUTE DISEASE; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; DISEASE MODELS, ANIMAL; DRACAENA; GENE EXPRESSION; INFLAMMATION MEDIATORS; INJECTIONS, INTRAPERITONEAL; MALE; NF-KAPPA B; PANCREATITIS; PHYTOTHERAPY; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; UMBELLIFERONES;

EID: 84959271557     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X16500105     Document Type: Article

References (30)

1. Algul, H., Y. Tando, G. Schneider, H. Weidenbach, G. Adler and R.M. Schmid. Acute experimental pancreatitis and NF-κB/Rel activation. Pancreatology 2: 503-509, 2002.
2. Awla, D., A. Abdulla, S. Regner and H. Thorlacius. TLR4 but not TLR2 regulates inflammation and tissue damage in acute pancreatitis induced by retrograde infusion of taurocholate. Inflamm. Res. 60: 1093-1098, 2011.
3. Blackwell, T. S. and J. W. Christman. The role of nuclear factor-κB in cytokine gene regulation. Am. J. Resp. Cell Mol. 17: 3-9, 1997.
4. Brady, M., S. Christmas, R. Sutton, J. Neoptolemos and J. Slavin. Cytokines and acute pancreatitis. Bailliere Clin. Gastr. 13: 265-289, 1999.
5. Chen, C.C., S.S. Wang, R.H. Lu, F.Y. Chang and S.D. Lee. Serum interleukin 10 and interleukin 11 in patients with acute pancreatitis. Gut 45: 895-899, 1999.
6. de Beaux, A.C., A. S. Goldie, J. A. Ross, D.C. Carter and K.C. Fearon. Serum concentrations of inflammatory mediators related to organ failure in patients with acute pancreatitis. Brit. J. Surg. 83: 349-353, 1996.
7. Feily, A. and H. Reza Fallahi. Potential utility of daphnetin as a novel treatment for pemphigus vulgaris. Giorn. Ital. Dermatol. Venereol. 145: 557-558, 2010.
8. Frossard, J. L., C. M. Pastor and A. Hadengue. Effect of hyperthermia on NF-κB binding activity in cerulein-induced acute pancreatitis. Am. J. Physiol.-Gastr. L. 280: G1157-1162, 2001.
9. Fylaktakidou, K.C., D.J. Hadjipavlou-Litina, K.E. Litinas and D.N. Nicolaides. Natural and synthetic coumarin derivatives with anti-inflammatory/antioxidant activities. Curr. Pharm. Design 10: 3813-3833, 2004.
10. Gao, Q., J. Shan, L. Di, L. Jiang and H. Xu. Therapeutic effects of daphnetin on adjuvant-induced arthritic rats. J. Ethnopharmacol. 120: 259-263, 2008.
11. Genovese, T., E. Mazzon, R. Di Paola, C. Muia, C. Crisafulli, M. Menegazzi, G. Malleo, H. Suzuki and S. Cuzzocrea. Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice. Shock 25: 161-167, 2006.
12. Grewal, H. P., M. Kotb, A.M. el Din, M. Ohman, A. Salem, L. Gaber and A.O. Gaber. Induction of tumor necrosis factor in severe acute pancreatitis and its subsequent reduction after hepatic passage. Surgery 115: 213-221, 1994.
13. Jaffray, C., J. Yang, G. Carter, C. Mendez and J. Norman. Pancreatic elastase activates pulmonary nuclear factor κB and inhibitory κB, mimicking pancreatitis-associated adult respiratory distress syndrome. Surgery 128: 225-231, 2000.
14. Laveda, R., J. Martinez, C. Munoz, J.C. Penalva, J. Saez, G. Belda, S. Navarro, F. Feu, A. Mas, J. M. Palazon, J. Sanchez-Paya, J. Such and M. Perez-Mateo. Different profile of cytokine synthesis according to the severity of acute pancreatitis. World J. Gastroenterol. 11: 5309-5313, 2005.
15. Leser, H. G., V. Gross, C. Scheibenbogen, A. Heinisch, R. Salm, M. Lausen, K. Ruckauer, R. Andreesen, E.H. Farthmann and J. Scholmerich. Elevation of serum interleukin-6 concentration precedes acute-phase response and reflects severity in acute pancreatitis. Gastro-enterology 101: 782-785, 1991.
16. Liu, Z. Y., J. Liu, K. L. Zhao, L. K. Wang, Q. Shi, T. Zuo, T.Y. Liu, L. Zhao and W.X. Wang. Protective effects of daphnetin on sodium taurocholate-induced severe acute pancreatitis in rats. Mol. Med. Rep. 9: 1709-1714, 2014.
17. Long, J., N. Song, X.P. Liu, K.J. Guo and R.X. Guo. Nuclear factor-κB activation on the reactive oxygen species in acute necrotizing pancreatitic rats. World J. Gastroenterol. 11: 4277-4280, 2005.
18. Makhija, R. and A.N. Kingsnorth. Cytokine storm in acute pancreatitis. J. Hepato-biliary-pan. 9: 401-410, 2002.
19. Osman, M. O., N.O. Jacobsen, J. U. Kristensen, B. Deleuran, B. Gesser, C.G. Larsen and S. L. Jensen. IT 9302, a synthetic interleukin-10 agonist, diminishes acute lung injury in rabbits with acute necrotizing pancreatitis. Surgery 124: 584-592, 1998.
20. Pezzilli, R., P. Billi, R. Miniero and B. Barakat. Serum interleukin-10 in human acute pancreatitis. Dig. Dis. Sci. 42: 1469-1472, 1997.
21. Rakonczay, Z., Jr., P. Hegyi, T. Takacs, J. McCarroll and A.K. Saluja. The role of NF-κB activation in the pathogenesis of acute pancreatitis. Gut 57: 259-267, 2008.
22. Raraty, M. G., S. Connor, D. N. Criddle, R. Sutton and J. P. Neoptolemos. Acute pancreatitis and organ failure: Pathophysiology, natural history, and management strategies. Curr. Gastro-enterol. Rep. 6: 99-103, 2004.
23. Satoh, A., T. Shimosegawa, M. Fujita, K. Kimura, A. Masamune, M. Koizumi and T. Toyota. Inhibition of nuclear factor-kappaB activation improves the survival of rats with taurocholate pancreatitis. Gut 44: 253-258, 1999.
24. Schmidt, J., D. W. Rattner, K. Lewandrowski, C. C. Compton, U. Mandavilli, W. T. Knoefel and A. L. Warshaw. A better model of acute pancreatitis for evaluating therapy. Ann. Surg. 215: 44-56, 1992.
25. Schneider, L., M. Pietschmann, W. Hartwig, S. S. Marcos, T. Hackert, M. M. Gebhard, W. Uhl, M. W. Buchler and J. Werner. Inosine reduces microcirculatory disturbance and inflammatory organ damage in experimental acute pancreatitis in rats. Am. J. Surg. 191: 510-514, 2006.
26. Tu, L., S. Li, Y. Fu, R. Yao, Z. Zhang, S. Yang, X. Zeng and N. Kuang. The therapeutic effects of daphnetin in collagen-induced arthritis involve its regulation of Th17 cells. Int. Immuno-pharmacol. 13: 417-423, 2012.
27. Yang, L., Q. Yang, K. Zhang, Y. J. Li, Y. M. Wu, S. B. Liu, L. H. Zheng and M. G. Zhao. Neuroprotective effects of daphnetin against NMDA receptor-mediated excitotoxicity. Molecules 19: 14542-14555, 2014.
28. Ye, B., Y. Q. Zheng, W. H. Wu and J. Zhang. Iron chelator daphnetin against Pneumocystis carinii in vitro. Chinese Med. J. Peking 117: 1704-1708, 2004.
29. Yesilada, E., H. Taninaka, Y. Takaishi, G. Honda, E. Sezik, H. Momota, Y. Ohmoto and T. Taki. In vitro inhibitory effects of Daphne oleoides ssp. oleoides on inflammatory cytokines and activity-guided isolation of active constituents. Cytokine 13: 359-364, 2001.
30. Zou, W. G., D. S. Wang, M. F. Lang, D. Y. Jin, D. H. Xu, Z. C. Zheng, Z. H. Wu and X. Y. Liu. Human interleukin 10 gene therapy decreases the severity and mortality of lethal pancreatitis in rats. J. Surg. Res. 103: 121-126, 2002.