Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 8, 2016, Pages 1987-1992

  Fay, Meredith E ^a,b,c   Myers, David R ^a,b,c   Kumar, Amit ^d   Turbyfield, Cory T ^a,e   Byler, Rebecca ^a,e   Crawford, Kaci ^a,e   Mannino, Robert G ^a,b,c   Laohapant, Alvin ^a,b,c   Tyburski, Erika A ^a,b,c   Sakurai, Yumiko ^a,b,c   Rosenbluth, Michael J ^a,b,c   Switz, Neil A ^f   Sulchek, Todd A ^e   Graham, Michael D ^d   Lam, Wilbur A ^a,b,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d University of Wisconsin Madison   (United States)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^f EVERGREEN STATE COLLEGE   (United States)

Author keywords

Atomic force microscopy; Cellular mechanics; Demargination; Leukocyte deformability; Microfluidics

Indexed keywords

ACTIN; ADRENALIN; CATECHOLAMINE; DEXAMETHASONE; GLUCOCORTICOID;

ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD CELL COUNT; CAPILLARY; CELL MIGRATION; CELLULAR PARAMETERS; GRANULOCYTE; HUMAN; HUMAN CELL; INNATE IMMUNITY; LEUKOCYTE ACTIVATION; LEUKOCYTE COUNT; LEUKOCYTE DEMARGINATION; LEUKOCYTE FUNCTION; MATHEMATICAL COMPUTING; MICROFLUIDICS; MICROVASCULATURE; NORMAL HUMAN; PRIORITY JOURNAL; RIGIDITY; STEM CELL MOBILIZATION; VEIN; BIOLOGICAL MODEL; CELL MOTION; CYTOLOGY; DEVICES; DRUG EFFECTS; FEMALE; LAB ON A CHIP; MALE; METABOLISM; PHYSIOLOGY; PROCEDURES;

CATECHOLAMINES; CELL MOVEMENT; FEMALE; GLUCOCORTICOIDS; GRANULOCYTES; HUMANS; LAB-ON-A-CHIP DEVICES; LEUKOCYTE COUNT; MALE; MODELS, CARDIOVASCULAR;

EID: 84959214243     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1508920113     Document Type: Article

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