Associations between vitamin B-12 status and oxidative stress and inflammation in diabetic vegetarians and omnivores

Nutrients

Volumn 8, Issue 3, 2016, Pages

  Lee, Yau Jiunn ^a   Wang, Ming Yang ^b   Lin, Mon Chiou ^c   Lin, Ping Ting ^d,e  

^a Lee's Endocrinologic Clinic   (Taiwan)

^b JEN AI HOSPITAL   (Taiwan)

^c Department of Dietetics and Nutrition   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Diabetes; Inflammation; Oxidative stress; Vegetarian; Vitamin B 12

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; C REACTIVE PROTEIN; CATALASE; CYANOCOBALAMIN; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; METFORMIN; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; AUTACOID; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; HEMOGLOBIN A1C PROTEIN, HUMAN; LIPID;

ADULT; AGED; ARTICLE; BLOOD BIOCHEMISTRY; CROSS-SECTIONAL STUDY; DIAGNOSTIC TEST; DIETARY INTAKE; ELECTROCHEMILUMINESCENCE IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; OMNIVORE; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; SPECTROPHOTOMETRY; VEGETARIAN; VEGETARIAN DIET; VITAMIN DEFICIENCY; BLOOD; COMPARATIVE STUDY; DIABETES MELLITUS, TYPE 2; FEEDING BEHAVIOR; MEAT; METABOLISM; NUTRITIONAL STATUS; PATHOPHYSIOLOGY; VERY ELDERLY; VITAMIN B 12 DEFICIENCY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS; BLOOD GLUCOSE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIET, VEGETARIAN; FEEDING BEHAVIOR; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LIPIDS; MALE; MEAT; MIDDLE AGED; NUTRITIONAL STATUS; OXIDATIVE STRESS; VEGETARIANS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY; YOUNG ADULT;

EID: 84959202706     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8030118     Document Type: Article

References (34)

1. Evatt, M.; Terry, P.D.; Ziegler, T.R.; Oakley, G.P. Association between vitamin B12-containing supplement consumption and prevalence of biochemically defined B12 deficiency in adults in NHANES III (third national health and nutrition examination survey). Public Health Nutr. 2010, 13, 25-31. [CrossRef] [PubMed]
2. Pawlak, R. Is vitamin B12 deficiency a risk factor for cardiovascular disease in vegetarians? Am. J. Prev. Med. 2015, 48, e11-e26. [CrossRef] [PubMed]
3. DeFronzo, R.A.; Goodman, A.M. The Multicenter Metformin Study Group. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. N. Engl. J. Med. 1995, 333, 541-549. [CrossRef] [PubMed]
4. De Jager, J.; Kooy, A.; Lehert, P.; Wulffelé, M.G.; van der Kolk, J.; Bets, D.; Verburg, J.; Donker, A.J.; Stehouwer, C.D. Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: Randomised placebo controlled trial. BMJ 2010, 340, c2181. [CrossRef] [PubMed]
5. Reinstatler, L.; Qi, Y.P.; Williamson, R.S.; Garn, J.V.; Oakley, G.P., Jr. Association of biochemical B12 deficiency with metformin therapy and vitamin B12 supplements: The National Health and Nutrition Examination Survey, 1999-2006. Diabetes Care 2012, 35, 327-333. [CrossRef] [PubMed]
6. Rains, J.L.; Jain, S.K. Oxidative stress, insulin signaling, and diabetes. Free Radic. Biol. Med. 2011, 50, 567-575. [CrossRef] [PubMed]
7. Al-Maskari, M.Y.; Waly, M.I.; Ali, A.; Al-Shuaibi, Y.S.; Ouhtit, A. Folate and vitamin B12 deficiency and hyperhomocysteinemia promote oxidative stress in adult type 2 diabetes. Nutrition 2012, 28, e23-e26. [CrossRef] [PubMed]
8. Birch, C.S.; Brasch, N.E.; McCaddon, A.; Williams, J.H. A novel role for vitamin B (12): Cobalamins are intracellular antioxidants in vitro. Free Radic. Biol. Med. 2009, 47, 184-188. [CrossRef] [PubMed]
9. Solomon, L.R. Functional cobalamin (vitamin B12) deficiency: Role of advanced age and disorders associated with increased oxidative stress. Eur. J. Clin. Nutr. 2015, 69, 687-692. [CrossRef] [PubMed]
10. Kräutler, B. Vitamin B12: Chemistry and biochemistry. Biochem. Soc. Trans. 2005, 33, 806-810. [CrossRef] [PubMed]
11. Ling, C.T.; Chow, B.F. Effect of vitamin B12 on the levels of soluble sulfhydryl compounds in blood. J. Biol. Chem. 1953, 202, 445-446. [PubMed]
12. McCaddon, A.; Regland, B.; Hudson, P.; Davies, G. Functional vitamin B12 deficiency and Alzheimer disease. Neurology 2002, 58, 1395-1399. [CrossRef] [PubMed]
13. Veber, D.; Mutti, E.; Tacchini, L.; Gammella, E.; Tredici, G.; Scalabrino, G. Indirect down-regulation of nuclear NF-kappaB levels by cobalamin in the spinal cord and liver of the rat. J. Neurosci. Res. 2008, 86, 1380-1387. [CrossRef] [PubMed]
14. Botsoglou, N.A. Rapid, sensitive, and specific thiobarbituric acid method for measuring lipid peroxidation in animal tissue, food and feedstuff samples. J. Agric. Food Chem. 1994, 42, 1931-1937. [CrossRef]
15. Aebi, H. Catalase in vitro. Methods Enzymol. 1984, 105, 121-126. [PubMed]
16. Marklund, S.; Marklund, G. Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974, 47, 469-474. [CrossRef] [PubMed]
17. Paglia, D.; Valentine, W. Studies on the qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 1967, 70, 159-169.
18. Barnard, N.D.; Katcher, H.I.; Jenkins, D.J.; Cohen, J.; Turner-McGrievy, G. Vegetarian and vegan diets in type 2 diabetes management. Nutr. Rev. 2009, 67, 255-263. [CrossRef] [PubMed]
19. Jenkins, D.J.; Kendall, C.W.; Marchie, A.; Jenkins, A.L.; Augustin, L.S.; Ludwig, D.S.; Barnard, N.D.; Anderson, J.W. Type 2 diabetes and the vegetarian diet. Am. J. Clin. Nutr. 2003, 78, 610S-616S. [PubMed]
20. Kahleova, H.; Pelikanova, T. Vegetarian diets in the prevention and treatment of type 2 diabetes. J. Am. Coll. Nutr. 2015, 27, 1-11. [CrossRef] [PubMed]
21. Sabaté, J.; Wien, M. A perspective on vegetarian dietary patterns and risk of metabolic syndrome. Br. J. Nutr. 2015, 113, S136-S143. [CrossRef] [PubMed]
22. Tonstad, S.; Butler, T.; Yan, R.; Fraser, G.E. Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care 2009, 32, 791-796. [CrossRef] [PubMed]
23. Manzanares, W.; Hardy, G. Vitamin B12: The forgotten micronutrient for critical care. Curr. Opin. Clin. Nutr. Metab. Care 2010, 13, 662-668. [CrossRef] [PubMed]
24. Wheatley, C. A scarlet pimpernel for the resolution of inflammation? The role of supra-therapeutic doses of cobalamin, in the treatment of systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, and septic or traumatic shock. Med. Hypotheses 2006, 67, 124-142. [CrossRef] [PubMed]
25. Dagnelie, P.C.; van Staveren, W.A.; van den Berg, H. Vitamin B-12 from algae appears not to be bioavailable. Am. J. Clin. Nutr. 1991, 53, 695-697. [PubMed]
26. Wheatley, C. The return of the Scarlet Pimpernel: Cobalamin in inflammation II—Cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS. J. Nutr. Environ. Med. 2007, 16, 181-211. [CrossRef] [PubMed]
27. Watanabe, F. Vitamin B12 sources and bioavailability. Exp. Biol. Med. 2007, 232, 1266-1274. [CrossRef] [PubMed]
28. Valdés-Ramos, R.; Guadarrama-López, A.L.; Martínez-Carrillo, B.E.; Benítez-Arciniega, A.D. Vitamins and type 2 diabetes mellitus. Endocr. Metab. Immune Disord. Drug Targets 2015, 15, 54-63. [CrossRef] [PubMed]
29. Chow, B.F.; Stone, H.H. The relationship of vitamin B12 to carbohydrate metabolism and diabetes mellitus. Am. J. Clin. Nutr. 1957, 5, 431-439. [PubMed]
30. Krishnaveni, G.V.; Hill, J.C.; Veena, S.R.; Bhat, D.S.; Wills, A.K.; Karat, C.L.; Yajnik, C.S.; Fall, C.H. Low plasma vitamin B12 in pregnancy is associated with gestational “diabesity” and later diabetes. Diabetologia 2009, 52, 2350-2358. [CrossRef] [PubMed]
31. Knight, B.A.; Shields, B.M.; Brook, A.; Hill, A.; Bhat, D.S.; Hattersley, A.T.; Yajnik, C.S. Lower Circulating B12 is associated with higher obesity and insulin resistance during pregnancy in a non-diabetic white British population. PLoS ONE 2015, 10, e0135268. [CrossRef] [PubMed]
32. Yajnik, C.S.; Deshpande, S.S.; Jackson, A.A.; Refsum, H.; Rao, S.; Fisher, D.J.; Bhat, D.S.; Naik, S.S.; Coyaji, K.J.; Joglekar, C.V., et al. Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: The Pune Maternal Nutrition Study. Diabetologia 2008, 51, 29-38. [CrossRef] [PubMed]
33. Stewart, C.P.; Christian, P.; Schulze, K.J.; Arguello, M.; LeClerq, S.C.; Khatry, S.K.; West, K.P., Jr. Low maternal vitamin B-12 status is associated with offspring insulin resistance regardless of antenatal micronutrient supplementation in rural Nepal. J. Nutr. 2011, 141, 1912-1917. [CrossRef] [PubMed]
34. Adaikalakoteswari, A.; Jayashri, R.; Sukumar, N.; Venkataraman, H.; Pradeepa, R.; Gokulakrishnan, K.; Anjana, R.M.; McTernan, P.G.; Tripathi, G.; Patel, V., et al. Vitamin B12 deficiency is associated with adverse lipid profile in Europeans and Indians with type 2 diabetes. Cardiovasc. Diabetol. 2014, 13, 129. [CrossRef] [PubMed]