Optimisation of a system for the co-translational incorporation of a keto amino acid and its application to a tumour-specific Anticalin

Protein Engineering, Design and Selection

Volumn 28, Issue 12, 2015, Pages 553-565

  Reichert, Andreas J ^a   Poxleitner, Gabriele ^a   Dauner, Martin ^a   Skerra, Arne ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Genetic code expansion; Keto functionalisation; Non canonical amino acid; Synthetic biology; Unnatural amino acid

Indexed keywords

AMBER; AUTOMATION; DIAGNOSIS; EFFICIENCY; ESCHERICHIA COLI; FLUORESCENCE; RECOMBINANT PROTEINS; SYNTHETIC BIOLOGY; TUMORS;

AUTOMATED SCREENING; ENHANCED GREEN FLUORESCENT PROTEIN; FUNCTIONALISATION; GENETIC CODE; METHANOCOCCUS JANNASCHII; NON-CANONICAL AMINO ACIDS; RADIOMETAL CHELATES; UNNATURAL AMINO ACIDS;

AMINO ACIDS;

AMINO ACID; ANTICALIN; BACTERIAL PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; FIBRONECTIN; OXOAMINO ACID; PROTEIN; TRANSFER RNA; TUMOR ANTIGEN; TYROSINE TRANSFER RNA LIGASE; UNCLASSIFIED DRUG; 3-(4-ACETYLPHENYL)-2-AMINOPROPANOIC ACID; ANTINEOPLASTIC AGENT; PHENYLALANINE; RECOMBINANT PROTEIN;

ARTICLE; BACTERIAL CELL; BIOSYNTHESIS; CELL SURFACE; COLON CANCER; ESCHERICHIA COLI; GENE CASSETTE; GENE EXPRESSION; GENETIC CODE; GENETIC SELECTION; HUMAN; HUMAN CELL; METHANOCALDOCOCCUS JANNASCHII; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STOP CODON; ANALOGS AND DERIVATIVES; CHEMISTRY; GENETICS; METABOLISM; PROCEDURES; PROTEIN ENGINEERING;

ANTINEOPLASTIC AGENTS; ESCHERICHIA COLI; PHENYLALANINE; PROTEIN ENGINEERING; PROTEIN MODIFICATION, TRANSLATIONAL; RECOMBINANT PROTEINS; RNA, TRANSFER;

EID: 84959195197     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzv048     Document Type: Article

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