Nonalcoholic steatohepatitis is strongly associated with sarcopenic obesity in patients with cirrhosis undergoing liver transplant evaluation

Journal of Gastroenterology and Hepatology (Australia)

Volumn 31, Issue 3, 2016, Pages 628-633

  Carias, Sandra ^a   Castellanos, Ana Lia ^a   Vilchez, Valery ^a   Nair, Rashmi ^a   Dela Cruz, Anna Christina ^a   Watkins, Jennifer ^a   Barrett, Terrence ^a   Trushar, Patel ^a   Esser, Karyn ^a   Gedaly, Roberto ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cirrhosis; Liver transplantation; Obesity; Sarcopenia

Indexed keywords

ADULT; ALCOHOL LIVER DISEASE; ARTICLE; BODY HEIGHT; BODY MASS; CHRONIC HEPATITIS C; COMPUTER ASSISTED TOMOGRAPHY; DEMOGRAPHY; DISEASE ASSOCIATION; END STAGE LIVER DISEASE; FEMALE; HOSPITAL READMISSION; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER GRAFT; MAJOR CLINICAL STUDY; MALE; MASS; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROGNOSIS; QUALITY OF LIFE; RETROSPECTIVE STUDY; SARCOPENIA; SARCOPENIC OBESITY; THERAPY EFFECT; AGED; COMPLICATION; LIVER TRANSPLANTATION; MIDDLE AGED; MORTALITY; OBESITY; RISK; SURVIVAL RATE; YOUNG ADULT;

ADULT; AGED; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; RETROSPECTIVE STUDIES; RISK; SARCOPENIA; SURVIVAL RATE; YOUNG ADULT;

EID: 84959095061     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.13166     Document Type: Article

References (30)

1. Sakuma K, A Yamaguchi. Sarcopenic obesity and endocrinal adaptation with age. Int J. Endocrinol. 2013; 2013: 204164.
2. Cesari M et al. Sarcopenia, obesity, and inflammation-results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study. Am. J. Clin. Nutr. 2005; 82: 428-34.
3. Roubenoff R. Sarcopenic obesity: the confluence of two epidemics. Obes. Res. 2004; 12: 887-8.
4. Batsis JA et al. Sarcopenia, sarcopenic obesity and mortality in older adults: results from the National Health and Nutrition Examination Survey III. Eur. J. Clin. Nutr. 2014; 68: 1001-7.
5. Kim TN et al. Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study. Int. J. Obes. (Lond) 2009; 33: 885-92.
6. Dasarathy S. Consilience in sarcopenia of cirrhosis. J Cachexia Sarcopenia Muscle. 2012; 3: 225-37.
7. Masuda T et al. Sarcopenia is a prognostic factor in living donor liver transplantation. Liver Transpl. 2014; 20: 401-7.
8. Montano-Loza AJ. Clinical relevance of sarcopenia in patients with cirrhosis. World J. Gastroenterol. 2014; 20: 8061-71.
9. Montano-Loza AJ et al. Severe muscle depletion predicts postoperative length of stay but is not associated with survival after liver transplantation. Liver Transpl. 2014; 20: 640-8.
10. Tandon P et al. Severe muscle depletion in patients on the liver transplant wait list: its prevalence and independent prognostic value. Liver Transpl. 2012; 18: 1209-16.
11. Englesbe MJ et al. Sarcopenia and mortality after liver transplantation. J. Am. Coll. Surg. 2010; 211: 271-8.
12. Hong HC et al. Relationship between sarcopenia and nonalcoholic fatty liver disease: the Korean Sarcopenic Obesity Study. Hepatology 2014; 59: 1772-8.
13. Kim TN et al. Relationships between sarcopenic obesity and insulin resistance, inflammation, and vitamin D status: the Korean Sarcopenic Obesity Study. Clin. Endocrinol. 2013; 78: 525-32.
14. Bertolotti M et al. Nonalcoholic fatty liver disease and aging: epidemiology to management. World J. Gastroenterol. 2014; 20: 14185-204.
15. Choi HY et al., Increased selenoprotein p levels in subjects with visceral obesity and nonalcoholic fatty liver disease. Diabetes Metab J. 2013; 37: 63-71.
16. Hui E et al. Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: role of adipokines. J. Diabetes Investig. 2013; 4: 413-25.
17. Montano-Loza AJ, Angulo P, Meza-Junco J, Prado CMM, Sawyer MB, Beaumont C, Esfandiari N, Ma M, Baracos VE. Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis. J. Cachex. Sarcopenia Muscle 2015, doi: 10.1002/jcsm.12039.
18. Durand F et al. Prognostic value of muscle atrophy in cirrhosis using psoas muscle thickness on computed tomography. J. Hepatol. 2014; 60: 1151-7.
19. Giusto M et al. Sarcopenia in liver cirrhosis: the role of computed tomography scan for the assessment of muscle mass compared with dual-energy X-ray absorptiometry and anthropometry. Eur. J. Gastroenterol. Hepatol. 2015; 27: 328-34.
20. Dasarathy S. Posttransplant sarcopenia: an underrecognized early consequence of liver transplantation. Dig. Dis. Sci. 2013; 58: 3103-11.
21. Bergerson JT et al. Liver transplantation arrests and reverses muscle wasting. Clin. Transplant. 2015; 29: 216-21.
22. Giusto M et al. Changes in nutritional status after liver transplantation. World J. Gastroenterol. 2014; 20: 10682-90.
23. Hamaguchi Y et al. Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation. Liver Transpl. 2014; 20: 1413-9.
24. Lorenzo MD et al. Sarcopenic obesity: correlation with clinical, functional, and psychological status in a rehabilitation setting. J. Nutr. Food Sci. 2014; 5: 2020-2031.
25. Stenholm S et al. Sarcopenic obesity: definition, cause and consequences. Curr. Opin. Clin. Nutr. Metab. Care 2008; 11: 693-700.
26. Schütz T et al. Weight gain in long-term survivors of kidney or liver transplantation-another paradigm of sarcopenic obesity? Nutrition 2012; 28: 378-383.
27. Kim MK et al. Vitamin D deficiency is associated with sarcopenia in older Koreans, regardless of obesity: the Fourth Korea National Health and Nutrition Examination Surveys (KNHANES IV) 2009. J. Clin. Endocrinol. Metab. 2011; 96: 3250-6.
28. Srikanthan P, AL Hevener, AS Karlamangla. Sarcopenia exacerbates obesity-associated insulin resistance and dysglycemia: findings from the National Health and Nutrition Examination Survey III. PLoS One 2010; 5: e10805.
29. Araki A, Z Heying, S Mori. Relationship between sarcopenic obesity or sarcopenia and insulin resistance or functional disability. Nihon Ronen Igakkai Zasshi 2012; 49: 210-3.
30. Levine ME, EM Crimmins. Sarcopenic obesity and cognitive functioning: the mediating roles of insulin resistance and inflammation? Curr. Gerontol. Geriatr. Res. 2012; 2012: 826398.