Post-treatment with cocaine- and amphetamine-regulated transcript enhances infarct resolution, reinnervation, and angiogenesis in stroke rats - an MRI study

NMR in Biomedicine

Volumn 29, Issue 3, 2016, Pages 361-370

  Liu, H S ^a,b,c,f   Shen, H ^a   Luo, Y ^d   Hoffer, B J ^a,d   Wang, Y ^e   Yang, Y ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^f Translational Imaging Research Center   (Taiwan)

Author keywords

Cocaine and amphetamine regulated transcript; Fractional anisotropy; MRI; Susceptibility weighted imaging

Indexed keywords

ANIMALS; ANISOTROPY; MAGNETIC RESONANCE IMAGING; NONINVASIVE MEDICAL PROCEDURES; PROTEINS; RATS; TENSORS;

COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT; FRACTIONAL ANISOTROPY; IMMUNOREACTIVITIES; MIDDLE CEREBRAL ARTERY OCCLUSIONS; NON-INVASIVE TREATMENT; POST TREATMENT; SMOOTH MUSCLE ACTINS; SUSCEPTIBILITY WEIGHTED IMAGING;

DIFFUSION TENSOR IMAGING;

ALPHA SMOOTH MUSCLE ACTIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; N ACETYLASPARTIC ACID; NERVE PROTEIN;

ADULT; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FOLLOW UP; FRACTIONAL ANISOTROPY; HEMISPHERE; IMMUNOREACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; REINNERVATION; SUSCEPTIBILITY WEIGHTED IMAGING; WHITE MATTER; ANIMAL; ANISOTROPY; CEREBRAL INFARCTION; COMPLICATION; DRUG EFFECTS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; STROKE; VASCULARIZATION;

ANIMALS; ANISOTROPY; CEREBRAL CORTEX; CEREBRAL INFARCTION; MAGNETIC RESONANCE IMAGING; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE TISSUE PROTEINS; RATS, SPRAGUE-DAWLEY; STROKE;

EID: 84959065316     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.3461     Document Type: Article

References (41)

1. Barber P, Zhang J, Demchuk A, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology 2001; 56(8): 1015-20.
2. Reed SD, Cramer SC, Blough DK, Meyer K, Jarvik JG. Treatment with tissue plasminogen activator and inpatient mortality rates for patients with ischemic stroke treated in community hospitals. Stroke 2001; 32(8): 1832-40.
3. Luo Y, Kuo CC, Shen H, Chou J, Greig NH, Hoffer BJ, Wang Y. Delayed treatment with a p53 inhibitor enhances recovery in stroke brain. Ann. Neurol. 2009; 65(5): 520-30.
4. Luo Y, Shen H, Liu HS, Yu SJ, Reiner DJ, Harvey BK, Hoffer BJ, Yang Y, Wang Y. CART peptide induces neuroregeneration in stroke rats. J. Cereb. Blood Flow Metab. 2013; 33(2): 300-10.
5. Douglass J, McKinzie AA, Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J. Neurosci. 1995; 15(3 Pt 2): 2471-81.
6. Xu Y, Zhang W, Klaus J, Young J, Koerner I, Sheldahl LC, Hurn PD, Martínez-Murillo F, Alkayed NJ. Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection. Proc. Natl. Acad. Sci. U. S. A. 2006; 103(39): 14489-94.
7. Roh MS, Cui FJ, Ahn YM, Kang UG. Up-regulation of cocaine- and amphetamine-regulated transcript (CART) in the rat nucleus accumbens after repeated electroconvulsive shock. Neurosci. Res. 2009; 65(2): 210-3.
8. Jia J, Chen X, Zhu W, Luo Y, Hua Z, Xu Y. CART protects brain from damage through ERK activation in ischemic stroke. Neuropeptides 2008; 42(5/6): 653-61.
9. Wang Y, Qiu B, Liu J, Zhu WG, Zhu S. Cocaine- and amphetamine-regulated transcript facilitates the neurite outgrowth in cortical neurons after oxygen and glucose deprivation through PTN-dependent pathway. Neuroscience 2014; 277: 103-10.
10. Haacke EM, Xu Y, Cheng YC, Reichenbach JR. Susceptibility weighted imaging (SWI). Magn. Reson. Med. 2004; 52(3): 612-8.
11. Borlongan CV, Hida H, Nishino H. Early assessment of motor dysfunctions aids in successful occlusion of the middle cerebral artery. Neuroreport 1998; 9(16): 3615-21.
12. Xiang QS, Ye FQ. Correction for geometric distortion and N/2 ghosting in EPI by phase labeling for additional coordinate encoding (PLACE). Magn. Reson. Med. 2007; 57(4): 731-41.
13. Chan KC, Khong PL, Lau HF, Cheung PT, Wu EX. Late measures of microstructural alterations in severe neonatal hypoxic-ischemic encephalopathy by MR diffusion tensor imaging. Int. J. Dev. Neurosci. 2009; 27(6): 607-15.
14. Liu HS, Shen H, Harvey BK, Castillo P, Lu H, Yang Y, Wang Y. Post-treatment with amphetamine enhances reinnervation of the ipsilateral side cortex in stroke rats. Neuroimage 2011; 56(1): 280-9.
15. Masutani Y, Aoki S, Abe O, Hayashi N, Otomo K. MR diffusion tensor imaging: recent advance and new techniques for diffusion tensor visualization. Eur. J. Radiol. 2003; 46(1): 53-66.
16. Phillips WEI, Velthuizen RP, Phuphanich S, Hall LO, Clarke LP, Silbiger ML. Application of fuzzy c-means segmentation technique for tissue differentiation in MR images of a hemorrhagic glioblastoma multiforme. Magn. Reson. Imaging 1995; 13(2): 277-90.
17. Wilson B, Dhas JPM. An experimental analysis of fuzzy c-means and k-means segmentation algorithm for iron detection in brain SWI using Matlab. Int. J. Comput. Appl. 2014; 104(15): 36-8.
18. Shen H, Wang Y. Correlation of locomotor activity and brain infarction in rats with transient focal ischemia. J. Neurosci. Methods 2010; 186(2): 150-4.
19. Abrahams JM, Gokhan S, Flamm ES, Mehler MF. De novo neurogenesis and acute stroke: are exogenous stem cells really necessary? Neurosurgery 2004; 54(1): 150-5.
20. Kawamata T, Dietrich WD, Schallert T, Gotts JE. R.R. C, Benowitz LI, Finklestein SP. Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc. Natl. Acad. Sci. U. S. A. 1997; 94(15): 8179-84.
21. Dijkhuizen RM, Ren J, Mandeville JB, Wu O, Ozdag FM, Moskowitz MA, Rosen BR, Finklestein SP. Functional magnetic resonance imaging of reorganization in rat brain after stroke. Proc. Natl. Acad. Sci. U. S. A. 2001; 98(22): 12766-71.
22. Provenzale JM, Liang L, DeLong D, White LE. Diffusion tensor imaging assessment of brain white matter maturation during the first postnatal year. Am. J. Roentgenol. 2007; 189(2): 476-86.
23. Löbel U, Sedlacik J, Güllmar D, Kaiser WA, Reichenbach JR, Mentzel HJ. Diffusion tensor imaging: the normal evolution of ADC, RA, FA, and eigenvalues studied in multiple anatomical regions of the brain. Neuroradiology 2009; 51(4): 253-63.
24. Font MA, Arboix A, Krupinski J. Angiogenesis, neurogenesis and neuroplasticity in ischemic stroke. Curr. Cardiol. Rev. 2010; 6(3): 238-44.
25. Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 1996; 16(9): 4604-13.
26. Teng H, Zhang ZG, Wang L, Zhang RL, Zhang L, Morris D, Gregg SR, Wu Z, Jiang A, Lu M, Zlokovic BV, Chopp M. Coupling of angiogenesis and neurogenesis in cultured endothelial cells and neural progenitor cells after stroke. J. Cereb. Blood Flow Metab. 2008; 28(4): 764-71.
27. Ding G, Jiang Q, Li L, Zhang L, Wang Y, Zhang ZG, Lu M, Panda S, Li Q, Ewing JR, Chopp M. Cerebral tissue repair and atrophy after embolic stroke in rat: a magnetic resonance imaging study of erythropoietin therapy. J. Neurosci. Res. 2010; 88(14): 3206-14.
28. Ding GL, Chopp M, Li L, Li Z, Zhang L, Zhang ZG, Li QJ, Jiang Q. Magnetic resonance imaging of stroke in the rat. Bo Pu Xue Za Zhi 2014; 31(1): 116-32.
29. Krupinski J, Kaluza J, Kumar P, Kumar S, Wang JM. Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 1994; 25(9): 1794-8.
30. Beck H, Plate KH. Angiogenesis after cerebral ischemia. Acta Neuropathol. 2009; 117(5): 481-96.
31. Wang L, Zhang Z, Wang Y, Zhang R, Chopp M. Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats. Stroke 2004; 35(7): 1732-7.
32. Li L, Jiang Q, Zhang L, Ding G, Gang ZZ, Li Q, Ewing JR, Lu M, Panda S, Ledbetter KA, Whitton PA, Chopp M. Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke. Brain Res. 2007; 1132(1): 185-92.
33. Lu H, Wang Y, He X, Yuan F, Lin X, Xie B, Tang G, Huang J, Tang Y, Jin K, Chen S, Yang GY. Netrin-1 hyperexpression in mouse brain promotes angiogenesis and long-term neurological recovery after transient focal ischemia. Stroke 2012; 43(3): 838-43.
34. Li Y, Huang J, He X, Tang G, Tang YH, Liu Y, Lin X, Lu Y, Yang GY, Wang Y. Postacute stromal cell-derived factor-1α expression promotes neurovascular recovery in ischemic mice. Stroke 2014; 45(6): 1822-9.
35. Ergul A, Alhusban A, Fagan SC. Angiogenesis: a harmonized target for recovery after stroke. Stroke 2012; 43(8): 2270-4.
36. Janiuk I, Olkowski B, Szczotka-Bochniarz A. Identification and differential distribution of CART in the small intestine depending on the diet. J. Anim. Physiol. Anim. Nutr. 2014; 98(6): 1117-23.
37. Arciszewski MB, Calka J, Majewski M. Cocaine- and amphetamine-regulated transcript (CART) is expressed in the ovine pancreas. Ann. Anat. 2008; 190(3): 292-9.
38. Iliff JJ, Alkayed NJ, Gloshani KJ, Traystman RJ, West GA. Cocaine- and amphetamine-regulated transcript (CART) peptide: a vasoactive role in the cerebral circulation. J. Cereb. Blood Flow Metab. 2005; 25(10): 1376-85.
39. Iliff JJ, Alkayed NJ, Golshani KJ, Weinstein J, Traystman RJ, West GA. In vivo cerebrovascular effects of cocaine- and amphetamine-regulated transcript (CART) peptide. J. Cardiovasc. Pharmacol. 2008; 52(1): 82-9.
40. Ding G, Jiang Q, Li L, Zhang L, Zhang ZG, Ledbetter KA, Gollapalli L, Panda S, Li Q, Ewing JR, Chopp M. Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI. Stroke 2008; 39(5): 1563-8.
41. Park MJ, Kim HS, Jahng GH, Ryu CW, Park SM, Kim SY. Semiquantitative assessment of intratumoral susceptibility signals using non-contrast-enhanced high-field high-resolution susceptibility-weighted imaging in patients with gliomas: comparison with MR perfusion imaging. Am. J. Neuroradiol. 2009; 30(7): 1402-8.