-
1
-
-
77952316009
-
Inflammatory bowel disease
-
Kaser, A., Zeissig, S. and Blumberg, R. S., Inflammatory bowel disease. Annu. Rev. Immunol. 2010. 28: 573-621.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 573-621
-
-
Kaser, A.1
Zeissig, S.2
Blumberg, R.S.3
-
2
-
-
34248136340
-
Inflammatory bowel disease: clinical aspects and established and evolving therapies
-
Baumgart, D. C. and Sandborn, W. J., Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007. 369: 1641-1657.
-
(2007)
Lancet
, vol.369
, pp. 1641-1657
-
-
Baumgart, D.C.1
Sandborn, W.J.2
-
3
-
-
77957346794
-
Risk factors associated with progression to intestinal complications of Crohn's disease in a population-based cohort
-
Thia, K. T., Sandborn, W. J., Harmsen, W. S., Zinsmeister, A. R. and Loftus, E. V., Jr., Risk factors associated with progression to intestinal complications of Crohn's disease in a population-based cohort. Gastroenterology 2010. 139: 1147-1155.
-
(2010)
Gastroenterology
, vol.139
, pp. 1147-1155
-
-
Thia, K.T.1
Sandborn, W.J.2
Harmsen, W.S.3
Zinsmeister, A.R.4
Loftus, E.V.5
-
4
-
-
0036061640
-
Long-term evolution of disease behavior of Crohn's disease
-
Cosnes, J., Cattan, S., Blain, A., Beaugerie, L., Carbonnel, F., Parc, R. and Gendre, J. P., Long-term evolution of disease behavior of Crohn's disease. Inflamm. Bowel Dis. 2002. 8: 244-250.
-
(2002)
Inflamm. Bowel Dis.
, vol.8
, pp. 244-250
-
-
Cosnes, J.1
Cattan, S.2
Blain, A.3
Beaugerie, L.4
Carbonnel, F.5
Parc, R.6
Gendre, J.P.7
-
5
-
-
84878759525
-
Crohn's disease complicated by strictures: a systematic review
-
Rieder, F., Zimmermann, E. M., Remzi, F. H. and Sandborn, W. J., Crohn's disease complicated by strictures: a systematic review. Gut 2013. 62: 1072-1084.
-
(2013)
Gut
, vol.62
, pp. 1072-1084
-
-
Rieder, F.1
Zimmermann, E.M.2
Remzi, F.H.3
Sandborn, W.J.4
-
6
-
-
84905483770
-
Mechanisms that mediate the development of fibrosis in patients with Crohn's disease
-
Li, C. and Kuemmerle, J. F., Mechanisms that mediate the development of fibrosis in patients with Crohn's disease. Inflamm. Bowel Dis. 2014. 20: 1250-1258.
-
(2014)
Inflamm. Bowel Dis.
, vol.20
, pp. 1250-1258
-
-
Li, C.1
Kuemmerle, J.F.2
-
7
-
-
84863702343
-
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
-
Wynn, T. A. and Ramalingam, T. R., Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat. Med. 2012. 18: 1028-1040.
-
(2012)
Nat. Med.
, vol.18
, pp. 1028-1040
-
-
Wynn, T.A.1
Ramalingam, T.R.2
-
8
-
-
0037484424
-
Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts: role of interleukin-17
-
Bamba, S., Andoh, A., Yasui, H., Araki, Y., Bamba, T. and Fujiyama, Y., Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts: role of interleukin-17. J. Gastroenterol. 2003. 38: 548-554.
-
(2003)
J. Gastroenterol.
, vol.38
, pp. 548-554
-
-
Bamba, S.1
Andoh, A.2
Yasui, H.3
Araki, Y.4
Bamba, T.5
Fujiyama, Y.6
-
9
-
-
66649106333
-
Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures
-
Di Sabatino, A., Jackson, C. L., Pickard, K. M., Buckley, M., Rovedatti, L., Leakey, N. A., Picariello L. et al., Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures. Gut 2009. 58: 777-789.
-
(2009)
Gut
, vol.58
, pp. 777-789
-
-
Di Sabatino, A.1
Jackson, C.L.2
Pickard, K.M.3
Buckley, M.4
Rovedatti, L.5
Leakey, N.A.6
Picariello, L.7
-
10
-
-
0036008967
-
Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblasts
-
Okuno, T., Andoh, A., Bamba, S., Araki, Y., Fujiyama, Y., Fujiyama, M. and Bamba, T., Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblasts. Scand. J. Gastroenterol. 2002. 37: 317-324.
-
(2002)
Scand. J. Gastroenterol.
, vol.37
, pp. 317-324
-
-
Okuno, T.1
Andoh, A.2
Bamba, S.3
Araki, Y.4
Fujiyama, Y.5
Fujiyama, M.6
Bamba, T.7
-
11
-
-
57249094020
-
IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis
-
2003-2013, 2013
-
Fichtner-Feigl, S., Young, C. A., Kitani, A., Geissler, E. K., Schlitt, H. J. and Strober, W., IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis. Gastroenterology 2008. 135: 2003-2013, 2013 e2001-e2007.
-
(2008)
Gastroenterology
, vol.135
, pp. e2001-e2007
-
-
Fichtner-Feigl, S.1
Young, C.A.2
Kitani, A.3
Geissler, E.K.4
Schlitt, H.J.5
Strober, W.6
-
12
-
-
84875535234
-
The immunology of fibrosis
-
Wick, G., Grundtman, C., Mayerl, C., Wimpissinger, T. F., Feichtinger, J., Zelger, B., Sgonc, R. et al., The immunology of fibrosis. Annu. Rev. Immunol. 2013. 31: 107-135.
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 107-135
-
-
Wick, G.1
Grundtman, C.2
Mayerl, C.3
Wimpissinger, T.F.4
Feichtinger, J.5
Zelger, B.6
Sgonc, R.7
-
13
-
-
0344792632
-
A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B
-
Lawrance, I. C., Wu, F., Leite, A. Z., Willis, J., West, G. A., Fiocchi, C. and Chakravarti, S., A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B. Gastroenterology 2003. 125: 1750-1761.
-
(2003)
Gastroenterology
, vol.125
, pp. 1750-1761
-
-
Lawrance, I.C.1
Wu, F.2
Leite, A.Z.3
Willis, J.4
West, G.A.5
Fiocchi, C.6
Chakravarti, S.7
-
14
-
-
0034116376
-
The PAS superfamily: sensors of environmental and developmental signals
-
Gu, Y. Z., Hogenesch, J. B. and Bradfield, C. A., The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 2000. 40: 519-561.
-
(2000)
Annu. Rev. Pharmacol. Toxicol.
, vol.40
, pp. 519-561
-
-
Gu, Y.Z.1
Hogenesch, J.B.2
Bradfield, C.A.3
-
15
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison, M. S. and Nagy, S. R., Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 2003. 43: 309-334.
-
(2003)
Annu. Rev. Pharmacol. Toxicol.
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
16
-
-
0029418619
-
Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands
-
Rannug, U., Rannug, A., Sjoberg, U., Li, H., Westerholm, R. and Bergman, J., Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands. Chem. Biol. 1995. 2: 841-845.
-
(1995)
Chem. Biol.
, vol.2
, pp. 841-845
-
-
Rannug, U.1
Rannug, A.2
Sjoberg, U.3
Li, H.4
Westerholm, R.5
Bergman, J.6
-
17
-
-
34447511096
-
The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
-
Barouki, R., Coumoul, X. and Fernandez-Salguero, P. M., The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett. 2007. 581: 3608-3615.
-
(2007)
FEBS Lett.
, vol.581
, pp. 3608-3615
-
-
Barouki, R.1
Coumoul, X.2
Fernandez-Salguero, P.M.3
-
18
-
-
84873318096
-
The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response
-
Quintana, F. J., The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response. Immunology 2013. 138: 183-189.
-
(2013)
Immunology
, vol.138
, pp. 183-189
-
-
Quintana, F.J.1
-
19
-
-
79959918506
-
Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract
-
Monteleone, I., Rizzo, A., Sarra, M., Sica, G., Sileri, P., Biancone, L., Macdonald, T. T. et al., Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract. Gastroenterology 2011. 141: 237-248, e231.
-
(2011)
Gastroenterology
, vol.141
, pp. 237-248
-
-
Monteleone, I.1
Rizzo, A.2
Sarra, M.3
Sica, G.4
Sileri, P.5
Biancone, L.6
Macdonald, T.T.7
-
20
-
-
79953647514
-
The aryl hydrocarbon receptor ligand ITE inhibits TGFbeta1-induced human myofibroblast differentiation
-
Lehmann, G. M., Xi, X., Kulkarni, A. A., Olsen, K. C., Pollock, S. J., Baglole, C. J., Gupta, S. et al., The aryl hydrocarbon receptor ligand ITE inhibits TGFbeta1-induced human myofibroblast differentiation. Am. J. Pathol. 2011. 178: 1556-1567.
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 1556-1567
-
-
Lehmann, G.M.1
Xi, X.2
Kulkarni, A.A.3
Olsen, K.C.4
Pollock, S.J.5
Baglole, C.J.6
Gupta, S.7
-
21
-
-
84893052989
-
Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Lahoti, T. S., Hughes, J. M., Kusnadi, A., John, K., Zhu, B., Murray, I. A., Gowda, K. et al., Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. J. Pharmacol. Exp. Ther. 2014. 348: 236-245.
-
(2014)
J. Pharmacol. Exp. Ther.
, vol.348
, pp. 236-245
-
-
Lahoti, T.S.1
Hughes, J.M.2
Kusnadi, A.3
John, K.4
Zhu, B.5
Murray, I.A.6
Gowda, K.7
-
22
-
-
84883785188
-
Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes
-
Lahoti, T. S., John, K., Hughes, J. M., Kusnadi, A., Murray, I. A., Krishnegowda, G., Amin, S. et al., Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes. Ann. Rheum. Dis. 2013. 72: 1708-1716.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 1708-1716
-
-
Lahoti, T.S.1
John, K.2
Hughes, J.M.3
Kusnadi, A.4
Murray, I.A.5
Krishnegowda, G.6
Amin, S.7
-
23
-
-
84891294432
-
Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin
-
Pierre, S., Chevallier, A., Teixeira-Clerc, F., Ambolet-Camoit, A., Bui, L. C., Bats, A. S., Fournet, J. C. et al., Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin. Toxicol. Sci. 2014. 137: 114-124.
-
(2014)
Toxicol. Sci.
, vol.137
, pp. 114-124
-
-
Pierre, S.1
Chevallier, A.2
Teixeira-Clerc, F.3
Ambolet-Camoit, A.4
Bui, L.C.5
Bats, A.S.6
Fournet, J.C.7
-
24
-
-
0029000839
-
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
-
Fernandez-Salguero, P., Pineau, T., Hilbert, D. M., McPhail, T., Lee, S. S., Kimura, S., Nebert, D. W. et al., Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science 1995. 268: 722-726.
-
(1995)
Science
, vol.268
, pp. 722-726
-
-
Fernandez-Salguero, P.1
Pineau, T.2
Hilbert, D.M.3
McPhail, T.4
Lee, S.S.5
Kimura, S.6
Nebert, D.W.7
-
25
-
-
4844221874
-
Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-beta-binding protein-1
-
Corchero, J., Martin-Partido, G., Dallas, S. L. and Fernandez-Salguero, P. M., Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-beta-binding protein-1. Int. J. Exp. Pathol. 2004. 85: 295-302.
-
(2004)
Int. J. Exp. Pathol.
, vol.85
, pp. 295-302
-
-
Corchero, J.1
Martin-Partido, G.2
Dallas, S.L.3
Fernandez-Salguero, P.M.4
-
26
-
-
0034106077
-
Hepatic fibrosis and cytochrome P450: experimental models of fibrosis compared to AHR knockout mice
-
Peterson, T. C., Hodgson, P., Fernandez-Salguero, P., Neumeister, M. and Gonzalez, F. J., Hepatic fibrosis and cytochrome P450: experimental models of fibrosis compared to AHR knockout mice. Hepatol. Res. 2000. 17: 112-125.
-
(2000)
Hepatol. Res.
, vol.17
, pp. 112-125
-
-
Peterson, T.C.1
Hodgson, P.2
Fernandez-Salguero, P.3
Neumeister, M.4
Gonzalez, F.J.5
-
27
-
-
34249845879
-
Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways
-
Pannu, J., Nakerakanti, S., Smith, E., ten Dijke, P. and Trojanowska, M., Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways. J. Biol. Chem. 2007. 282: 10405-10413.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10405-10413
-
-
Pannu, J.1
Nakerakanti, S.2
Smith, E.3
ten Dijke, P.4
Trojanowska, M.5
-
28
-
-
84904062548
-
TNF and MAP kinase signalling pathways
-
Sabio, G. and Davis, R. J., TNF and MAP kinase signalling pathways. Semin. Immunol. 2014. 26: 237-245.
-
(2014)
Semin. Immunol.
, vol.26
, pp. 237-245
-
-
Sabio, G.1
Davis, R.J.2
-
29
-
-
80052875424
-
TGF-beta signaling in fibrosis
-
Biernacka, A., Dobaczewski, M. and Frangogiannis, N. G., TGF-beta signaling in fibrosis. Growth Factors 2011. 29: 196-202.
-
(2011)
Growth Factors
, vol.29
, pp. 196-202
-
-
Biernacka, A.1
Dobaczewski, M.2
Frangogiannis, N.G.3
-
30
-
-
34247586091
-
Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis
-
Fichtner-Feigl, S., Fuss, I. J., Young, C. A., Watanabe, T., Geissler, E. K., Schlitt, H. J., Kitani, A. et al., Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2, 4, 6-trinitrobenzene sulfonic acid colitis. J. Immunol. 2007. 178: 5859-5870.
-
(2007)
J. Immunol.
, vol.178
, pp. 5859-5870
-
-
Fichtner-Feigl, S.1
Fuss, I.J.2
Young, C.A.3
Watanabe, T.4
Geissler, E.K.5
Schlitt, H.J.6
Kitani, A.7
-
31
-
-
30044449492
-
IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
-
Fichtner-Feigl, S., Strober, W., Kawakami, K., Puri, R. K. and Kitani, A., IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat. Med. 2006. 12: 99-106.
-
(2006)
Nat. Med.
, vol.12
, pp. 99-106
-
-
Fichtner-Feigl, S.1
Strober, W.2
Kawakami, K.3
Puri, R.K.4
Kitani, A.5
-
32
-
-
33947706133
-
Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut
-
Andoh, A., Bamba, S., Brittan, M., Fujiyama, Y. and Wright, N. A., Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut. Pharmacol. Ther. 2007. 114: 94-106.
-
(2007)
Pharmacol. Ther.
, vol.114
, pp. 94-106
-
-
Andoh, A.1
Bamba, S.2
Brittan, M.3
Fujiyama, Y.4
Wright, N.A.5
-
33
-
-
84895783781
-
Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling
-
Wang, C., Xu, C. X., Bu, Y., Bottum, K. M. and Tischkau, S. A., Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling. Carcinogenesis 2014. 35: 703-713.
-
(2014)
Carcinogenesis
, vol.35
, pp. 703-713
-
-
Wang, C.1
Xu, C.X.2
Bu, Y.3
Bottum, K.M.4
Tischkau, S.A.5
-
34
-
-
59149097969
-
The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways
-
Puga, A., Ma, C. and Marlowe, J. L., The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways. Biochem. Pharmacol. 2009. 77: 713-722.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 713-722
-
-
Puga, A.1
Ma, C.2
Marlowe, J.L.3
-
35
-
-
84866631453
-
Tacrolimus (FK506) suppresses TNF-alpha-induced CCL2 (MCP-1) and CXCL10 (IP-10) expression via the inhibition of p38 MAP kinase activation in human colonic myofibroblasts
-
Aomatsu, T., Imaeda, H., Takahashi, K., Fujimoto, T., Kasumi, E., Yoden, A., Tamai, H. et al., Tacrolimus (FK506) suppresses TNF-alpha-induced CCL2 (MCP-1) and CXCL10 (IP-10) expression via the inhibition of p38 MAP kinase activation in human colonic myofibroblasts. Int. J. Mol. Med. 2012. 30: 1152-1158.
-
(2012)
Int. J. Mol. Med.
, vol.30
, pp. 1152-1158
-
-
Aomatsu, T.1
Imaeda, H.2
Takahashi, K.3
Fujimoto, T.4
Kasumi, E.5
Yoden, A.6
Tamai, H.7
-
36
-
-
33845447347
-
Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21
-
Monteleone, G., Caruso, R., Fina, D., Peluso, I., Gioia, V., Stolfi, C., Fantini, M. C. et al., Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21. Gut 2006. 55: 1774-1780.
-
(2006)
Gut
, vol.55
, pp. 1774-1780
-
-
Monteleone, G.1
Caruso, R.2
Fina, D.3
Peluso, I.4
Gioia, V.5
Stolfi, C.6
Fantini, M.C.7
|