Cesarean Section Delivery Is Not a Risk Factor for Development of Inflammatory Bowel Disease: A Population-based Analysis

Clinical Gastroenterology and Hepatology

Volumn 14, Issue 1, 2016, Pages 50-57

  Bernstein, Charles N ^a   Banerjee, Ankona ^a,b   Targownik, Laura E ^a   Singh, Harminder ^a   Ghia, Jean Eric ^a   Burchill, Charles ^b   Chateau, Dan ^b   Roos, Leslie L ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Breastfeeding; Method of Birth; Population Study; UMIBDED

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BREAST FEEDING; CESAREAN SECTION; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; HUMAN; INCOME; INFANT; INFLAMMATORY BOWEL DISEASE; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; NEWBORN; POPULATION RESEARCH; RISK FACTOR; SEX DIFFERENCE; URBAN RURAL DIFFERENCE; VAGINAL DELIVERY; ADVERSE EFFECTS; INFLAMMATORY BOWEL DISEASES; MANITOBA; PRESCHOOL CHILD; UNIVERSITY HOSPITAL; YOUNG ADULT;

ADOLESCENT; ADULT; CESAREAN SECTION; CHILD; CHILD, PRESCHOOL; FEMALE; HOSPITALS, UNIVERSITY; HUMANS; INFANT; INFLAMMATORY BOWEL DISEASES; MALE; MANITOBA; RISK FACTORS; YOUNG ADULT;

EID: 84958978835     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2015.08.005     Document Type: Article

References (31)

1. Chassaing B., Darfeuille-Michaud A. Commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011, 140:1720-1728.
2. Palmer C., Bik E.M., Digiulio D.B., et al. Development of the human infant intestinal microbiota. PLOS Biology 2007.
3. Stark P.L., Lee A. The microbial ecology of the large bowel of breast-fed and formula-fed infants during the first year of life. J Med Microbiol 1982, 15:189-203.
4. Dominguez-Bello M.G., Blaser M.G., Ley R.E., et al. Developments of the human intestinal microbiota and insights from high throughput sequencing. Gastroenterology 2011, 140:1713-1719.
5. Ng S., Bernstein C.N., Vatn M.H., et al. Geographic variability and environmental risk factors in inflammatory bowel disease. Gut 2013, 62:630-649.
6. Shaw S., Blanchard J.F., Bernstein C.N. Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease. Am J Gastroenterol 2010, 105:2687-2692.
7. Minkoff H., Chervenak F.A. Elective primary cesarean delivery. N Engl J Med 2003, 348:946-950.
8. Klemetti R., Che X., Gao Y., et al. Cesarean delivery among primiparous women in rural China: an emerging epidemic. Am J Obstet Gynecol 2010, 202:1-6.
9. Grönlund M.M., Lehtonen O.P., Eerola E., et al. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr 1999, 28:19-25.
10. Dominguez-Bello M.G., Costello E.K., Contreras M., et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. PNAS 2010, 107:11971-11975.
11. Salminen S., Gibson G.R., McCartney A.L., et al. Influence of mode of delivery on gut microbiota composition in seven year old children. Gut 2004, 53:1388-1389.
12. Li Y., Tian Y., Zhu W., et al. Cesarian delivery and risk of inflammatory bowel disease: a systematic review and meta-analysis. Scand J Gastroenterol 2014, 49:834-844.
13. Ponsoby A.L., Catto-Smith A.G., Pezic A., et al. Association between early-life factors and risk of child-onset Crohn's disease among Victorian children born 1983-1998: a birth cohort study. Inflamm Bowel Dis 2009, 15:858-866.
14. Bager P., Simonsen J., Nielsen N.M., et al. Cesarean section and offspring's risk of inflammatory bowel disease: a national cohort study. Inflamm Bowel Dis 2012, 18:857-862.
15. Malborg P., Brahmanyar S., Grahnquist L., et al. Cesarean section and the risk of pediatric Crohn's disease. Inflamm Bowel Dis 2012, 18:703-708.
16. Sonntag B., Stolze B., Heinecke A., et al. Preterm birth but not mode of delivery is associated with an increased risk of developing inflammatory bowel disease later in life. Inflamm Bowel Dis 2007, 13:1385-1390.
17. Decker E., Engelmann G., Findeisen A., et al. Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. Pediatrics 2010, 125:1433-1440.
18. Hutfless S., Li D.K., Heyman M.B., et al. Prenatal and perinatal characteristics associated with pediatric-onset inflammatory bowel disease. Dig Dis Sci 2012, 57:2149-2156.
19. Roberts S.E., Wotton C.J., Williams J.G., et al. Perinatal and early life risk factors for inflammatory bowel disease. World J Gastroenterol 2011, 17:743-749.
20. Bernstein C.N., Blanchard J.F., Rawsthorne P., et al. The epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study. Am J Epidemiol 1999, 149:916-924.
21. Jutte D.P., Roos L.L., Brownell M.D. Administrative record linkage as a tool for public health research. Annu Rev Public Health 2011, 32:91-108.
22. Chateau D., Metge C., Prior H., et al. Learning from the census: the Socio-economic Factor Index (SEFI) and health outcomes in Manitoba. Can J Public Health 2012, 103:S23-S27.
23. Andersen V., Erichsen R., Froslev T., et al. Differential risk of ulcerative colitis and Crohn's disease among boys and girls after caesarean delivery. Inflamm Bowel Dis 2013, 19:E8-E10.
24. Bengtson M.B., Solberg I.C., Aamodt G., et al. Relationships between inflammatory bowel disease and perinatal factors: both maternal and paternal disease are related to preterm birth of offspring. Inflamm Bowel Dis 2010, 16:847-855.
25. Thavagnanam S., Fleming J., Bromley A., et al. A meta-analysis of the association between Caesarean section and childhood asthma. Clin Exp Allergy 2007, 38:629-633.
26. Cardwell C.R., Stene L.C., Joner G., et al. Caesarian section is associated with an increased risk of childhood-onset type I diabetes mellitus: a meta-analysis of observational studies. Diabetologia 2008, 51:726-735.
27. Gronlund M.M., Lehtonen O.P., Eerola E., et al. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after caesarean delivery. J Pediatr Gastroenterol Nutr 1999, 28:19-25.
28. Edwards C.A., Parrett A.M. Intestinal flora during the first months of life. Br J Nutr 2002, 88(Suppl 1):S11-S18.
29. Klement E., Cohen R.V., Boxman J., et al. Breastfeeding and risk of inflammatory bowel disease: a systematic review with metaanalysis. Am J Clin Nutr 2004, 80:1342-1352.
30. Baron S., Turck D., Leplat C., et al. Environmental risk factors in pediatric inflammatory bowel diseases: a population-based case-control study. Gut 2005, 54:357-363.
31. Friedman N.J., Zieger R.S. The role of breastfeeding in the development of allergies and asthma. J Allergy Clin Immunol 2005, 115:1238-1248.