Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families

Journal of Medical Genetics

Volumn 53, Issue 1, 2016, Pages 34-42

  Li, Jun ^a   Meeks, Huong ^b   Feng, Bing Jian ^c   Healey, Sue ^a   Thorne, Heather ^d,e   Makunin, Igor ^a   Ellis, Jonathan ^a   Campbell, Ian ^d   Southey, Melissa ^e   Mitchell, Gillian ^d,e   Clouston, David ^f   Kirk, Judy ^g,h   Goldgar, David ^b,c   Chenevix Trench, Georgia ^a   kConFab Investigators, ^d  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f Tissupath Pty Ltd   (Australia)

^g UNIVERSITY OF SYDNEY   (Australia)

^h WESTMEAD HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA1 PROTEIN; BRCA2 PROTEIN; BRIP1 PROTEIN; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 4; MRE11 PROTEIN; PALB2 PROTEIN; PROTEIN; PROTEIN KINASE LKB1; PROTEIN P53; RAD50 PROTEIN; RAD51C PROTEIN; RAD51D PROTEIN; TENOFOVIR 3 HEXADECYLOXYPROPYL ESTER; UNCLASSIFIED DRUG; UVOMORULIN; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER FAMILY; CANCER RISK; CLINICAL ASSESSMENT; COHORT ANALYSIS; DISEASE ASSOCIATION; EXON; FAMILY ASSESSMENT; FAMILY HISTORY; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MAXIMUM LIKELIHOOD METHOD; OVARY CANCER; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SEQUENCE ANALYSIS; BIOLOGY; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; GERMLINE MUTATION; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HIGH THROUGHPUT SEQUENCING; MALE; MUTATION; ODDS RATIO; OVARIAN NEOPLASMS; PEDIGREE; PROCEDURES; TUMOR SUPPRESSOR GENE;

BIOMARKERS, TUMOR; COMPUTATIONAL BIOLOGY; EXONS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOTYPE; GERM-LINE MUTATION; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MUTATION; ODDS RATIO; OVARIAN NEOPLASMS; PEDIGREE;

EID: 84958949508     PISSN: 00222593     EISSN: 14686244     Source Type: Journal    
DOI: 10.1136/jmedgenet-2015-103452     Document Type: Article

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