Supplemental iron intake and the risk of glucose intolerance in pregnancy: Re-analysis of a randomised controlled trial in Finland

Maternal and Child Nutrition

Volumn 12, Issue 1, 2016, Pages 74-84

  Kinnunen, Tarja I ^a   Luoto, Riitta ^b,c   Helin, Annika ^a   Hemminki, Elina ^c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UKK INSTITUTE FOR HEALTH PROMOTION RESEARCH   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Gestational diabetes; Glucose intolerance; Iron supplementation; Pregnancy; Randomised controlled trial

Indexed keywords

GLUCOSE; HEMOGLOBIN; IRON; IRON INTAKE;

ANEMIA; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FINLAND; GESTATIONAL AGE; GLUCOSE INTOLERANCE; GLUCOSURIA; HUMAN; IRON INTAKE; LARGE FOR GESTATIONAL AGE; NUTRITIONAL ASSESSMENT; OBSERVATIONAL STUDY; PREGNANCY; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PUERPERIUM; RISK ASSESSMENT; RISK FACTOR; VITAMIN SUPPLEMENTATION; WEIGHT GAIN; ADULT; ADVERSE EFFECTS; BIRTH WEIGHT; CLINICAL TRIAL; COMPARATIVE STUDY; DIABETES, GESTATIONAL; DIET THERAPY; DIETARY SUPPLEMENT; FETAL MACROSOMIA; FOLLOW UP; INCIDENCE; IRON DEFICIENCY ANEMIA; MALE; MATERNAL NUTRITION; MULTICENTER STUDY; NEWBORN; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; THERAPEUTIC USE; YOUNG ADULT;

ADULT; ANEMIA, IRON-DEFICIENCY; BIRTH WEIGHT; DIABETES, GESTATIONAL; DIETARY SUPPLEMENTS; FEMALE; FETAL MACROSOMIA; FINLAND; FOLLOW-UP STUDIES; GLUCOSE INTOLERANCE; HUMANS; INCIDENCE; INFANT, NEWBORN; IRON, DIETARY; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PREGNANCY; RISK FACTORS; WEIGHT GAIN; YOUNG ADULT;

EID: 84958907340     PISSN: 17408695     EISSN: 17408709     Source Type: Journal    
DOI: 10.1111/mcn.12139     Document Type: Article

References (40)

1. Afkhami-Ardekani M. & Rashidi M. (2009) Iron status in women with and without gestational diabetes mellitus. Journal of Diabetes and Its Complications 23 (3), 194-198.
2. American Diabetes Association (2003) Gestational diabetes mellitus. Diabetes Care 26 (Suppl. 1), S103-S105.
3. American Diabetes Association (2013) Diagnosis and classification of diabetes mellitus. Diabetes Care 36 (Suppl. 1), S67-S74.
4. Arkkola T., Uusitalo U., Pietikainen M., Metsala J., Kronberg-Kippila C., Erkkola M. etal. (2006) Dietary intake and use of dietary supplements in relation to demographic variables among pregnant Finnish women. The British Journal of Nutrition 96 (5), 913-920.
5. Bo S., Menato G., Villois P., Gambino R., Cassader M., Cotrino I. etal. (2009) Iron supplementation and gestational diabetes in midpregnancy. American Journal of Obstetrics and Gynecology 201 (2), 158.e1-158.e6.
6. Bowers K., Yeung E., Williams M.A., Qi L., Tobias D.K., Hu F.B. etal. (2011) A prospective study of prepregnancy dietary iron intake and risk for gestational diabetes mellitus. Diabetes Care 34 (7), 1557-1563.
7. Cao C. & O'Brien K.O. (2013) Pregnancy and iron homeostasis: an update. Nutrition Reviews 71 (1), 35-51.
8. Central Statistical Office of Finland (1981) Classification of Occupations 1980. Handbooks, No 14. Central Statistical Office of Finland: Helsinki.
9. Chan K.K., Chan B.C., Lam K.F., Tam S. & Lao T.T. (2009) Iron supplement in pregnancy and development of gestational diabetes - a randomised placebo-controlled trial. BJOG: An International Journal of Obstetrics and Gynaecology 116 (6), 789-797; discussion 797-798.
10. Chen X., Scholl T.O. & Stein T.P. (2006) Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women: the Camden study. Diabetes Care 29 (5), 1077-1082.
11. Clausen T.D., Mathiesen E.R., Hansen T., Pedersen O., Jensen D.M., Lauenborg J. etal. (2008) High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia. Diabetes Care 31 (2), 340-346.
12. Clausen T.D., Mathiesen E.R., Hansen T., Pedersen O., Jensen D.M., Lauenborg J. etal. (2009) Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism 94 (7), 2464-2470.
13. Dabelea D. (2007) The predisposition to obesity and diabetes in offspring of diabetic mothers. Diabetes Care 30 (Suppl. 2), S169-S174.
14. Derbent A.U., Simavli S.A., Kaygusuz I., Gumus I.I., Yilmaz S., Yildirim M. etal. (2013) Serum hepcidin is associated with parameters of glucose metabolism in women with gestational diabetes mellitus. The Journal of Maternal-Fetal & Neonatal Medicine26(11), 1112-1115.
15. Ferrara A. (2007) Increasing prevalence of gestational diabetes mellitus: a public health perspective. Diabetes Care 30 (Suppl. 2), S141-S146.
16. Galtier F. (2010) Definition, epidemiology, risk factors. Diabetes & Metabolism 36 (6 Pt 2), 628-651.
17. HAPO Study Cooperative Research Group, Metzger B.E., Lowe L.P., Dyer A.R., Trimble E.R., Chaovarindr U. etal. (2008) Hyperglycemia and adverse pregnancy outcomes. The New England Journal of Medicine 358 (19), 1991-2002.
18. Helin A., Kinnunen T.I., Raitanen J., Ahonen S., Virtanen S.M. & Luoto R. (2012) Iron intake, haemoglobin and risk of gestational diabetes: a prospective cohort study. BMJ Open 2 (5), 1-8. doi:10.1136/bmjopen-2012-001730. Print 2012.
19. Hemminki E. & Merilainen J. (1995) Long-term follow-up of mothers and their infants in a randomized trial on iron prophylaxis during pregnancy. American Journal of Obstetrics and Gynecology 173 (1), 205-209.
20. Hemminki E. & Rimpela U. (1991a) Iron supplementation, maternal packed cell volume, and fetal growth. Archives of Disease in Childhood 66 (4 Spec No), 422-425.
21. Hemminki E. & Rimpela U. (1991b) A randomized comparison of routine versus selective iron supplementation during pregnancy. Journal of the American College of Nutrition 10 (1), 3-10.
22. Hemminki E., Uski A., Koponen P. & Rimpela U. (1989) Iron supplementation during pregnancy - experiences of a randomized trial relying on health service personnel. Controlled Clinical Trials 10 (3), 290-298.
23. Hemminki E., Rimpela U. & Yla-Outinen A. (1991) Iron prophylaxis during pregnancy and infections. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 61 (4), 370-371.
24. Hyvönen K. (1991) Gestaatiodiabeteksen esiintyvyys ja seulonta. University of Kuopio.
25. IOM (Institute of Medicine) (2009) Weight Gain During Pregnancy: Reexamining the Guidelines. The National Academies Press: Washington, DC.
26. Ju H., Rumbold A.R., Willson K.J. & Crowther C.A. (2008) Borderline gestational diabetes mellitus and pregnancy outcomes. BMC Pregnancy and Childbirth 8, 31-2393-8-31.
27. Kim C., Newton K.M. & Knopp R.H. (2002) Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 25 (10), 1862-1868.
28. Kim S.Y., England L., Wilson H.G., Bish C., Satten G.A. & Dietz P. (2010) Percentage of gestational diabetes mellitus attributable to overweight and obesity. American Journal of Public Health 100 (6), 1047-1052.
29. Lao T.T. & Ho L.F. (2004) Impact of iron deficiency anemia on prevalence of gestational diabetes mellitus. Diabetes Care 27 (3), 650-656.
30. Lao T.T., Chan P.L. & Tam K.F. (2001) Gestational diabetes mellitus in the last trimester - a feature of maternal iron excess? Diabetic Medicine: A Journal of the British Diabetic Association 18 (3), 218-223.
31. Lao T.T., Chan L.Y., Tam K.F. & Ho L.F. (2002) Maternal hemoglobin and risk of gestational diabetes mellitus in Chinese women. Obstetrics and Gynecology 99 (5 Pt 1), 807-812.
32. Lee A.J., Hiscock R.J., Wein P., Walker S.P. & Permezel M. (2007) Gestational diabetes mellitus: clinical predictors and long-term risk of developing type 2 diabetes: a retrospective cohort study using survival analysis. Diabetes Care 30 (4), 878-883.
33. Mainous A.G. 3rd, Wells B.J., Everett C.J., Gill J.M. & King D.E. (2004) Association of ferritin and lipids with C-reactive protein. The American Journal of Cardiology 93 (5), 559-562.
34. National Institute for Health and Welfare (2012) Perinatal statistics: parturients, deliveries and newborns 2011. Official Statistics of Finland, Health 2012. Statistical report 20/2012. National Institute for Health and Welfare, Helsinki.
35. Pirkola J., Pouta A., Bloigu A., Hartikainen A.L., Laitinen J., Jarvelin M.R. etal. (2010) Risks of overweight and abdominal obesity at age 16 years associated with prenatal exposures to maternal prepregnancy overweight and gestational diabetes mellitus. Diabetes Care 33 (5), 1115-1121.
36. Qiu C., Zhang C., Gelaye B., Enquobahrie D.A., Frederick I.O. & Williams M.A. (2011) Gestational diabetes mellitus in relation to maternal dietary heme iron and nonheme iron intake. Diabetes Care 34 (7), 1564-1569.
37. Soubasi V., Petridou S., Sarafidis K., Tsantali C., Diamanti E., Buonocore G. etal. (2010) Association of increased maternal ferritin levels with gestational diabetes and intra-uterine growth retardation. Diabetes & Metabolism 36 (1), 58-63.
38. Stotland N.E., Caughey A.B., Breed E.M. & Escobar G.J. (2004) Risk factors and obstetric complications associated with macrosomia. International Journal of Gynaecology and Obstetrics: The Official Organ of the International Federation of Gynaecology and Obstetrics 87 (3), 220-226.
39. Wendland E.M., Torloni M.R., Falavigna M., Trujillo J., Dode M.A., Campos M.A. etal. (2012) Gestational diabetes and pregnancy outcomes - a systematic review of the World Health Organization (WHO) and the International Association of Diabetes in Pregnancy Study Groups (IADPSG) diagnostic criteria. BMC Pregnancy and Childbirth 12, 23-2393-12-23.
40. Williams M.J., Poulton R. & Williams S. (2002) Relationship of serum ferritin with cardiovascular risk factors and inflammation in young men and women. Atherosclerosis 165 (1), 179-184.