-
1
-
-
84892805731
-
Cancer statistics
-
PMID: 24399786
-
Siegel R et al (2014) Cancer statistics, 2014 CA Cancer J Clin 64(1) 9-29 DOI: 10.3322/caac.21208 PMID: 24399786
-
(2014)
2014 CA Cancer J Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
-
2
-
-
84920947978
-
The 2015 who classification of lung tumors
-
PMID: 25394966
-
Travis WD (2014) The 2015 WHO classification of lung tumors Pathologe 35(Suppl 2) 188 DOI: 10.1007/s00292-014-1974-3 PMID: 25394966
-
(2014)
Pathologe
, vol.35
, pp. 188
-
-
Travis, W.D.1
-
3
-
-
84947903456
-
-
American Cancer Society Available at [accessed January 1 2015]
-
American Cancer Society Non-small cell lung cancer survival rates by stage Available at: http://cancer.org/cancer/lungcancernon smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates [accessed January 1, 2015]
-
Non-Small Cell Lung Cancer Survival Rates by Stage
-
-
-
4
-
-
84911493241
-
Metastatic non-small-cell lung cancer (NSCLC) esmo clinical practice guidelines for diagnosis, treatment and follow-up
-
PMID: 25115305
-
Reck M et al (2014) Metastatic non-small-cell lung cancer (NSCLC): ESMO clinical practice guidelines for diagnosis, treatment and follow-up Ann Oncol 25(suppl 3) iii27-39 DOI: 10.1093/annonc/mdu199 PMID: 25115305
-
(2014)
Ann Oncol
, vol.25
, pp. iii27-39
-
-
Reck, M.1
-
5
-
-
84866167321
-
Advances on EGFR mutation for lung cancer
-
PMID: 25806150 PMCID 4367583
-
Metro G and Crinó L (2012) Advances on EGFR mutation for lung cancer Transl Lung Cancer Res 1(1) 5-13 PMID: 25806150 PMCID: 4367583
-
(2012)
Transl Lung Cancer Res
, vol.1
, Issue.1
, pp. 5-13
-
-
Metro, G.1
Crinó, L.2
-
6
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
PMID: 19692680
-
Mok TS et al (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma N Engl J Med 361(10) 947-57 DOI: 10.1056/NEJMoa0810699 PMID: 19692680
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
-
7
-
-
79960702788
-
Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (ipass
-
PMID: 21670455
-
Fukuoka M et al (2011) Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS) J Clin Oncol 29(21) 2866-74 DOI: 10.1200/JCO.2010.33.4235 PMID: 21670455
-
(2011)
J Clin Oncol
, vol.29
, Issue.21
, pp. 2866-2874
-
-
Fukuoka, M.1
-
8
-
-
84861976809
-
First-signal first-line single-Agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung
-
PMID: 22370314
-
Han JY et al (2012) First-SIGNAL: first-line single-Agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung J Clin Oncol 30(10) 1122-8 DOI: 10.1200/JCO.2011.36.8456 PMID: 22370314
-
(2012)
J Clin Oncol
, vol.30
, Issue.10
, pp. 1122-1128
-
-
Han, J.Y.1
-
9
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
PMID: 20573926
-
Maemondo M et al (2010) Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR N Engl J Med 362(25) 2380-8 DOI: 10.1056/NEJMoa0909530 PMID: 20573926
-
(2010)
N Engl J Med
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
-
10
-
-
84871597401
-
Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatinpaclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene mutations (nej002
-
Inoue A et al (2013) Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatinpaclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002) Ann Oncol 24(1) 54-9 DOI: 10.1093/annonc/mds214
-
(2013)
Ann Oncol
, vol.24
, Issue.1
, pp. 54-59
-
-
Inoue, A.1
-
11
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patient with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (wjtog3405) an open label, randomised phase 3 trial
-
PMID: 20022809
-
Mitsudomi T et al Gefitinib versus cisplatin plus docetaxel in patient with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial Lancet Oncol 11(2) 121-8 PMID: 20022809
-
Lancet Oncol
, vol.11
, Issue.2
, pp. 121-128
-
-
Mitsudomi, T.1
-
12
-
-
84921525233
-
Final overall survival results of wjtog 3405, a randomized phase 3 trial comparing gefitinib (g) with cisplatin plus docetaxel (cd) as the first-line treatment for patients with non-small cell lung cancer (NSCLC) harboring mutations of the epidermal growth factor receptor (EGFR
-
abstr 8117
-
Yoshioka H et al (2014) Final overall survival results of WJTOG 3405, a randomized phase 3 trial comparing gefitinib (G) with cisplatin plus docetaxel (CD) as the first-line treatment for patients with non-small cell lung cancer (NSCLC) harboring mutations of the epidermal growth factor receptor (EGFR) J Clin Oncol 32 (suppl 5; abstr 8117)
-
(2014)
J Clin Oncol
, vol.32
-
-
Yoshioka, H.1
-
13
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (optimal, ctong-0802) a multicentre, open-label, randomised, phase 3 study
-
Zhou C et al (2011) Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study Lancet Oncol 12(8) 735-42 DOI: 10.1016/S1470-2045(11)70184-X PMID: 21783417
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
-
14
-
-
84866756012
-
Overall survival (os) results from optimal (ctong0802), a phase III trial of erlotinib (e) versus carboplatin plus gemcitabine (gc) as first-line treatment for Chinese patients with EGFR mutation-positive advanced non-small cell lung cancer (NSCLC
-
abstr 7520
-
Zhou C et al (2012) Overall survival (OS) results from OPTIMAL (CTONG0802), a phase III trial of erlotinib (E) versus carboplatin plus gemcitabine (GC) as first-line treatment for Chinese patients with EGFR mutation-positive advanced non-small cell lung cancer (NSCLC) J Clin Oncol 30 (suppl; abstr 7520)
-
(2012)
J Clin Oncol
, vol.30
-
-
Zhou, C.1
-
15
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for european patients with advanced EGFR mutation-positive non-small-cell lung cancer (eurtac) a multicentre, open-label, randomised phase 3 trial
-
Rosell R et al (2012) Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial Lancet Oncol 13(3) 239-46 DOI: 10.1016/S1470-2045(11)70393-X PMID: 22285168
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
-
16
-
-
84884736973
-
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
-
PMID: 23816960
-
Sequist LV et al (2013) Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations J Clin Oncol 31(27) 3327-34 DOI: 10.1200/JCO.2012.44.2806 PMID: 23816960
-
(2013)
J Clin Oncol
, vol.31
, Issue.27
, pp. 3327-3334
-
-
Sequist, L.V.1
-
17
-
-
84921892043
-
Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (lux-lung 3 and lux-lung 6) analysis of overall survival data from two randomised, phase 3 trials
-
PMID: 25589191
-
Yang JC et al (2015) Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials Lancet Oncol 16(2) 141-51 DOI: 10.1016/S1470-2045(14)71173-8 PMID: 25589191
-
(2015)
Lancet Oncol
, vol.16
, Issue.2
, pp. 141-151
-
-
Yang, J.C.1
-
18
-
-
84892997539
-
Afatinib versus cisplatin plus gemcitabine for first-line treatment of asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (lux-lung 6) an open-label, randomised phase 3 trial
-
PMID: 24439929
-
Wu YL et al (2014) Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial Lancet Oncol 15(2) 213-22 DOI: 10.1016/S1470-2045(13)70604-1 PMID: 24439929
-
(2014)
Lancet Oncol
, vol.15
, Issue.2
, pp. 213-222
-
-
Wu, Y.L.1
-
19
-
-
74549114727
-
Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer
-
Mitsudomi T and Yatabe Y (2010) Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer FEBS J 277(2) 301-8 DOI: 10.1111/j.1742-4658.2009.07448.x
-
(2010)
FEBS J
, vol.277
, Issue.2
, pp. 301-308
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
20
-
-
36048985044
-
The epidermal growth factor receptor: From development to tumorigenesis
-
PMID: 17999740
-
Sibilia M et al (2007) The epidermal growth factor receptor: from development to tumorigenesis Differentiation 75(9) 770-87 DOI: 10.1111/j.1432-0436.2007.00238.x PMID: 17999740
-
(2007)
Differentiation
, vol.75
, Issue.9
, pp. 770-787
-
-
Sibilia, M.1
-
21
-
-
18644370411
-
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha
-
PMID: 12297049
-
Garrett TP et al (2002) Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha Cell 110(6) 763-73 DOI: 10.1016/S0092-8674(02)00940-6 PMID: 12297049
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 763-773
-
-
Garrett, T.P.1
-
22
-
-
52649160344
-
EGFR family: Structure physiology signalling and therapeutic targets growth
-
PMID: 18800267
-
Burgess AW (2008) EGFR family: structure physiology signalling and therapeutic targets Growth Factors 26(5) 263-74 DOI: 10.1080/08977190802312844 PMID: 18800267
-
(2008)
Factors
, vol.26
, Issue.5
, pp. 263-274
-
-
Burgess, A.W.1
-
23
-
-
33746133158
-
Biological and clinical implications of EGFR mutations in lung cancer
-
PMID: 16850125
-
Mitsudomi T, Kosaka T and Yatabe Y (2006) Biological and clinical implications of EGFR mutations in lung cancer Int J Clin Oncol 11(3) 190-20 DOI: 10.1007/s10147-006-0583-4 PMID: 16850125
-
(2006)
Int J Clin Oncol
, vol.11
, Issue.3
, pp. 190-220
-
-
Mitsudomi, T.1
Kosaka, T.2
Yatabe, Y.3
-
24
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
PMID: 17318210
-
Sharma SV et al (2007) Epidermal growth factor receptor mutations in lung cancer Nat Rev Cancer 7(3) 169-81 DOI: 10.1038/nrc2088 PMID: 17318210
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.3
, pp. 169-181
-
-
Sharma, S.V.1
-
25
-
-
52749083383
-
Somatic mutations of the tyrosine kinase domain of the epidermal growth factor receptor and tyrosine kinase inhibitor response to tkis in non-small cell lung cancer an analytical database
-
PMID: 18670300
-
Murray S et al (2008) Somatic mutations of the tyrosine kinase domain of the epidermal growth factor receptor and tyrosine kinase inhibitor response to TKIs in non-small cell lung cancer: an analytical database J Thorac Oncol 3(8) 832-9 DOI: 10.1097/JTO.0b013e31818071f3 PMID: 18670300
-
(2008)
J Thorac Oncol
, vol.3
, Issue.8
, pp. 832-839
-
-
Murray, S.1
-
26
-
-
79957916527
-
Effectiveness of tyrosine kinase inhibitors on uncommon epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer
-
PMID: 21531810
-
Wu JY et al (2011) Effectiveness of tyrosine kinase inhibitors on uncommon epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer Clin Cancer Res 17(11) 3812-21 DOI: 10.1158/1078-0432.CCR-10-3408 PMID: 21531810
-
(2011)
Clin Cancer Res
, vol.17
, Issue.11
, pp. 3812-3821
-
-
Wu, J.Y.1
-
27
-
-
80054931335
-
Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harbouring rare epidermal growth factor receptor mutations
-
PMID: 21841502
-
De Pas T et al (2011) Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harbouring rare epidermal growth factor receptor mutations J Thorac Oncol 6(11) 1895-901 DOI: 10.1097/JTO.0b013e318227e8c6 PMID: 21841502
-
(2011)
J Thorac Oncol
, vol.6
, Issue.11
, pp. 1895-1901
-
-
De Pas, T.1
-
28
-
-
84942933131
-
Activity of afatinib in uncommon epidermal growth factor receptor (EGFR mutations: Findings from three trials of afatinib in EGFR mutation-positive lung cancer oral
-
Yang JC et al (2013) Activity of afatinib in uncommon epidermal growth factor receptor (EGFR) mutations: findings from three trials of afatinib in EGFR mutation-positive lung cancer Oral presentation at: World Congress on Lung Cancer
-
(2013)
Presentation At: World Congress on Lung Cancer
-
-
Yang, J.C.1
-
29
-
-
84938278221
-
Epidermal growth factor receptor tyrosine kinase inhibitor treatment response in advanced lung adenocarcinomas with g719x/l861q/s768i mutations
-
PMID: 25668120
-
Chiu CH et al (2015) Epidermal growth factor receptor tyrosine kinase inhibitor treatment response in advanced lung adenocarcinomas with G719X/L861Q/S768I mutations J Thorac Oncol 10(5) 793-9 DOI: 10.1097/JTO.0000000000000504 PMID: 25668120
-
(2015)
J Thorac Oncol
, vol.10
, Issue.5
, pp. 793-799
-
-
Chiu, C.H.1
-
30
-
-
84884605223
-
Symptom control and quality of life in lux-lung 3 a phase III study of afatinib or cisplatin/pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations
-
PMID: 23816967
-
Yang JC et al (2013) Symptom control and quality of life in LUX-Lung 3: a phase III study of afatinib or cisplatin/pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations J Clin Oncol 31(27) 3342-50 DOI: 10.1200/JCO.2012.46.1764 PMID: 23816967
-
(2013)
J Clin Oncol
, vol.31
, Issue.27
, pp. 3342-3350
-
-
Yang, J.C.1
-
31
-
-
84904692834
-
Overall survival (os) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (del19/l858r) epidermal growth factor receptor mutations (EGFR mut): Pooled analysis of two large openlabel phase III studies (lux-lung 3 [ll3] and lux-lung 6 [ll6]) comparing afatinib with chemotherapy (ct
-
abstr 8004
-
Yang JC-H et al (2014) Overall survival (OS) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor mutations (EGFR mut): pooled analysis of two large openlabel phase III studies (LUX-Lung 3 [LL3] and LUX-Lung 6 [LL6]) comparing afatinib with chemotherapy (CT) J Clin Oncol 32(Suppl):abstr 8004
-
(2014)
J Clin Oncol
, vol.32
-
-
Yang, J.C.-H.1
-
32
-
-
74949110711
-
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Jackman D et al (2010) Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer J Clin Oncol 28(2) 357-60 DOI: 10.1200/JCO.2009.24.7049
-
(2010)
J Clin Oncol
, vol.28
, Issue.2
, pp. 357-360
-
-
Jackman, D.1
-
33
-
-
51049116207
-
Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib gefitinib tretment response
-
PMID: 18676761
-
Wu JY et al (2008) Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib gefitinib tretment response Clin Cancer Res 14(15) 4877-82 DOI: 10.1158/1078-0432.CCR-07-5123 PMID: 18676761
-
(2008)
Clin Cancer Res
, vol.14
, Issue.15
, pp. 4877-4882
-
-
Wu, J.Y.1
-
34
-
-
84863011443
-
Pretreatment epidermal growth factor receptor (EGFR t790m mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer
-
PMID: 22215752
-
Su KY et al (2012) Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer J Clin Oncol 30(4) 433-40 DOI: 10.1200/JCO.2011.38.3224 PMID: 22215752
-
(2012)
J Clin Oncol
, vol.30
, Issue.4
, pp. 433-440
-
-
Su, K.Y.1
-
35
-
-
84898726862
-
The impact of EGFR t790m mutations and bim mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III eurtac trial
-
PMID: 24493829
-
Costa C et al (2014) The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFR-mutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial Clin Cancer Res 20(7) 2001-10 DOI: 10.1158/1078-0432.CCR-13-2233 PMID: 24493829
-
(2014)
Clin Cancer Res
, vol.20
, Issue.7
, pp. 2001-2010
-
-
Costa, C.1
-
36
-
-
78449283888
-
Loss of pten expression by blocking nuclear translocation of egr1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-Activating mutations
-
PMID 20959484
-
Yamamoto C et al (2010) Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-Activating mutations Cancer Res 70(21) 8715-25 DOI: 10.1158/0008-5472. CAN-10-0043 PMID: 20959484
-
(2010)
Cancer Res
, vol.70
, Issue.21
, pp. 8715-8725
-
-
Yamamoto, C.1
-
37
-
-
65949086609
-
Pten loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of akt and EGFR
-
PMID: 19351834 PMCID 2849653
-
Sos ML et al (2009) PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR Cancer Res 69(8) 3256-61 DOI: 10.1158/0008-5472.CAN-08-4055 PMID: 19351834 PMCID: 2849653
-
(2009)
Cancer Res
, vol.69
, Issue.8
, pp. 3256-3261
-
-
Sos, M.L.1
-
38
-
-
84895788351
-
Pik3ca mutations frequently coexist with EGFR/kras mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/kras wildtype subgroup
-
PMID: 24533074 PMCID 3922761
-
Wang L et al (2014) PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup PLoS One 9(2) e88291 DOI: 10.1371/journal.pone.0088291 PMID: 24533074 PMCID: 3922761
-
(2014)
PLoS One
, vol.9
, Issue.2
, pp. e88291
-
-
Wang, L.1
-
39
-
-
33749435816
-
Allelic dilution obscures detection of a biologically significant resistance mutation in egframplified lung cancer
-
PMID: 16906227 PMCID 1570180
-
Engelman JA et al (2006) Allelic dilution obscures detection of a biologically significant resistance mutation in EGFRamplified lung cancer J Clin Invest 116(10) 2695-706 DOI: 10.1172/JCI28656 PMID: 16906227 PMCID: 1570180
-
(2006)
J Clin Invest
, vol.116
, Issue.10
, pp. 2695-2706
-
-
Engelman, J.A.1
-
40
-
-
84862777672
-
A common bim deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
-
PMID: 22426421
-
Ng KP et al (2012) A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer Nat Med 18(4) 521-8 DOI: 10.1038/nm.2713 PMID: 22426421
-
(2012)
Nat Med
, vol.18
, Issue.4
, pp. 521-528
-
-
Ng, K.P.1
-
41
-
-
84898726862
-
The impact of EGFR t790m mutations and bim mRNA expression on outcome in patients with EGFRmutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III eurtac trial
-
PMID: 24493829
-
Costa C et al (2014) The impact of EGFR T790M mutations and BIM mRNA expression on outcome in patients with EGFRmutant NSCLC treated with erlotinib or chemotherapy in the randomized phase III EURTAC trial Clin Cancer Res 20(7) 2001-10 DOI: 10.1158/1078-0432.CCR-13-2233 PMID: 24493829
-
(2014)
Clin Cancer Res
, vol.20
, Issue.7
, pp. 2001-2010
-
-
Costa, C.1
-
42
-
-
84875950992
-
Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease
-
PMID: 23401451 PMCID 3589701
-
Ohashi K et al (2013) Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease J Clin Oncol 31(8) 1070-80 DOI: 10.1200/JCO.2012.43.3912 PMID: 23401451 PMCID: 3589701
-
(2013)
J Clin Oncol
, vol.31
, Issue.8
, pp. 1070-1080
-
-
Ohashi, K.1
-
43
-
-
40049099220
-
The t790m mutation in EGFR kinase causes drug resistance by increasing the affinity for atp
-
PMID: 18227510 PMCID 2538882
-
Yun CH et al (2008) The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP Proc Natl Acad Sci USA 105(6) 2070-5 DOI: 10.1073/pnas.0709662105 PMID: 18227510 PMCID: 2538882
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.6
, pp. 2070-2075
-
-
Yun, C.H.1
-
44
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
PMID: 18596266 PMCID 3551471
-
Maheswaran S et al (2008) Detection of mutations in EGFR in circulating lung-cancer cells N Engl J Med 359(4) 366-77 DOI: 10.1056/NEJMoa0800668 PMID: 18596266 PMCID: 3551471
-
(2008)
N Engl J Med
, vol.359
, Issue.4
, pp. 366-377
-
-
Maheswaran, S.1
-
45
-
-
33751292685
-
Novel d761y and common secondary t790m mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors
-
PMID: 17085664
-
Balak MN et al (2006) Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors Clin Cancer Res 12(21) 6494-501 DOI: 10.1158/1078-0432.CCR-06-1570 PMID: 17085664
-
(2006)
Clin Cancer Res
, vol.12
, Issue.21
, pp. 6494-6501
-
-
Balak, M.N.1
-
46
-
-
58149333768
-
Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel t854a mutation in a patient with EGFR-mutant lung adenocarcinoma
-
PMID: 19010870 PMCID 2596620
-
Bean J et al (2008) Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma Clin Cancer Res 14(22) 7519-25 DOI: 10.1158/1078-0432.CCR-08-0151 PMID: 19010870 PMCID: 2596620
-
(2008)
Clin Cancer Res
, vol.14
, Issue.22
, pp. 7519-7525
-
-
Bean, J.1
-
47
-
-
70349464846
-
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway
-
PMID: 19632948 PMCID 2758558
-
Nguyen KS, Kobayashi S and Costa DB (2009) Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancers Dependent on the Epidermal Growth Factor Receptor Pathway Clin Lung Cancer 10(4) 281-9 DOI: 10.3816/CLC.2009.n.039 PMID: 19632948 PMCID: 2758558
-
(2009)
Clin Lung Cancer
, vol.10
, Issue.4
, pp. 281-289
-
-
Nguyen, K.S.1
Kobayashi, S.2
Costa, D.B.3
-
48
-
-
34249075147
-
Met amplification leads to gefitinib resistance in lung cancer by activating erbb3 signaling
-
PMID: 17463250
-
Engelman JA et al (2007) MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling Science 316(5827) 1039-43 DOI: 10.1126/science.1141478 PMID: 17463250
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
-
49
-
-
56449089812
-
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-Activating mutations
-
PMID: 19010923
-
Yano S et al (2008) Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-Activating mutations Cancer Res 68(22) 9479-87 DOI: 10.1158/0008-5472.CAN-08-1643 PMID: 19010923
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9479-9487
-
-
Yano, S.1
-
50
-
-
81755185464
-
Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort
-
PMID: 22052230
-
Yano S et al (2011) Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort J Thorac Oncol 6(12) 2011-7 DOI: 10.1097/JTO.0b013e31823ab0dd PMID: 22052230
-
(2011)
J Thorac Oncol
, vol.6
, Issue.12
, pp. 2011-2017
-
-
Yano, S.1
-
51
-
-
73649102105
-
Preexistence and clonal selection of met amplification in EGFR mutant NSCLC cancer
-
PMID: 20129249 PMCID 2980857
-
Turke AB et al (2010) Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC Cancer Cell 17(1) 77-88 DOI: 10.1016/j.ccr.2009.11.022 PMID: 20129249 PMCID: 2980857
-
(2010)
Cell
, vol.17
, Issue.1
, pp. 77-88
-
-
Turke, A.B.1
-
52
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
PMID: 21430269 PMCID 3132801
-
Sequist LV et al (2011) Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors Sci Transl Med 3(75) 75ra26 PMID: 21430269 PMCID: 3132801
-
(2011)
Sci Transl Med
, vol.3
, Issue.75
, pp. 75ra26
-
-
Sequist, L.V.1
-
53
-
-
84877100240
-
Analysis of tumour specimens at the time of acquired resistance to EGFR tki therapy in 155 patients with EGFR-mutant lung cancers
-
PMID: 23470965 PMCID 3630270
-
Yu HA et al (2013) Analysis of tumour specimens at the time of acquired resistance to EGFR TKI therapy in 155 patients with EGFR-mutant lung cancers Clin Cancer Res 19(8) 2240-7 DOI: 10.1158/1078-0432.CCR-12-2246 PMID: 23470965 PMCID: 3630270
-
(2013)
Clin Cancer Res
, vol.19
, Issue.8
, pp. 2240-2247
-
-
Yu, H.A.1
-
54
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
PMID: 16493418
-
Thiery JP and Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions Nat Rev Mol Cell Biol 7(2) 131-42 DOI: 10.1038/nrm1835 PMID: 16493418
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.2
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
55
-
-
79959872399
-
Epithelial to mesenchymal transition in an epidermal growth factor receptor mutant lung cancer cell line with acquired resistance to erlotinib
-
PMID: 21597390
-
Suda K et al (2011) Epithelial to mesenchymal transition in an epidermal growth factor receptor mutant lung cancer cell line with acquired resistance to erlotinib J Thorac Oncol 6(7) 1152-61 DOI: 10.1097/JTO.0b013e318216ee52 PMID: 21597390
-
(2011)
J Thorac Oncol
, vol.6
, Issue.7
, pp. 1152-1161
-
-
Suda, K.1
-
56
-
-
24644487312
-
Tgf-? and epithelial-to-mesenchymal transitions
-
PMID: 16123809
-
Zavadil J and Bottinger EP (2005) TGF-? and epithelial-to-mesenchymal transitions Oncogene 24(37) 5764-74 DOI: 10.1038/sj.onc.1208927 PMID: 16123809
-
(2005)
Oncogene
, vol.24
, Issue.37
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
57
-
-
84859095585
-
Activation of notch-1 enhances epithelial-mesenchymal transition in gefitinib acquired resistant lung cancer cells
-
Xie M et al (2012) Activation of Notch-1 enhances epithelial-mesenchymal transition in gefitinib acquired resistant lung cancer cells J Cell Biochem 113(5) 1501-13
-
(2012)
J Cell Biochem
, vol.113
, Issue.5
, pp. 1501-1513
-
-
Xie, M.1
-
58
-
-
84864402225
-
Activation of the axl kinase causes resistance to EGFR-targeted therapy in lung cancer
-
PMID: 22751098 PMCID 3408577
-
Zhang Z et al (2012) Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer Nat Genet 44(8) 852-60 DOI: 10.1038/ng.2330 PMID: 22751098 PMCID: 3408577
-
(2012)
Nat Genet
, vol.44
, Issue.8
, pp. 852-860
-
-
Zhang, Z.1
-
59
-
-
84877100240
-
Analysis of tumor specimens at the time of acquired resistance to EGFR-tki therapy in 155 patients with EGFR-mutant lung cancers
-
PMID: 23470965 PMCID 3630270
-
Yu HA et al (2013) Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers Clin Cancer Res 19(8) 2240-7 DOI: 10.1158/1078-0432.CCR-12-2246 PMID: 23470965 PMCID: 3630270
-
(2013)
Clin Cancer Res
, vol.19
, Issue.8
, pp. 2240-2247
-
-
Yu, H.A.1
-
60
-
-
77957982985
-
Microrna in lung cancer
-
PMID: 20859290 PMCID 2967070
-
Lin PY, Yu SL and Yang PC (2010) MicroRNA in lung cancer Br J Cancer 103(8) 1144-8 DOI: 10.1038/sj.bjc.6605901 PMID: 20859290 PMCID: 2967070
-
(2010)
Br J Cancer
, vol.103
, Issue.8
, pp. 1144-1148
-
-
Lin, P.Y.1
Yu, S.L.2
Yang, P.C.3
-
61
-
-
77955902024
-
The widespread regulation of microrna biogenesis function and decay
-
PMID: 20661255
-
Krol J, Loedige I and Filipowicz W (2010) The widespread regulation of microRNA biogenesis, function and decay Nat Rev Genet 11(9) 597-610 PMID: 20661255
-
(2010)
Nat Rev Genet
, vol.11
, Issue.9
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
62
-
-
84863429647
-
Micrornas and lung cancers: From pathogenesis to clinical implications
-
PMID: 22528868 PMCID 3725603
-
Qi J and Mu D (2012) MicroRNAs and lung cancers: from pathogenesis to clinical implications Front Med 6(2) 134-55 DOI: 10.1007/s11684-012-0188-4 PMID: 22528868 PMCID: 3725603
-
(2012)
Front Med
, vol.6
, Issue.2
, pp. 134-155
-
-
Qi, J.1
Mu, D.2
-
63
-
-
84958783522
-
Correlation of circulating mirna levels with progression-free survival (pfs) and overall survival (os in early-stage lung adenocarcinoma
-
abstr 11099
-
Grignani F et al (2014) Correlation of circulating miRNA levels with progression-free survival (PFS) and overall survival (OS) in early-stage lung adenocarcinoma J Clin Oncol 32 (suppl 5; abstr 11099)
-
(2014)
J Clin Oncol
, vol.32
-
-
Grignani, F.1
-
64
-
-
78650385772
-
Microrna-21 a novel therapeutic target in human cancer
-
PMID: 21139417
-
Pan X, Wang ZX and Wang R (2010) MicroRNA-21 A novel therapeutic target in human cancer Cancer Biol Ther 10(12) 1224-32 DOI: 10.4161/cbt.10.12.14252 PMID: 21139417
-
(2010)
Cancer Biol Ther
, vol.10
, Issue.12
, pp. 1224-1232
-
-
Pan, X.1
Wang, Z.X.2
Wang, R.3
-
65
-
-
78751642778
-
Upregulationof mir-21 by ras in vivo and its role in tumor growth
-
Frezzetti D et al (2011) Upregulationof miR-21 by Ras in vivo and its role in tumor growth Oncogene 30(3) 275-86 DOI: 10.1038/onc.2010.416
-
(2011)
Oncogene
, vol.30
, Issue.3
, pp. 275-286
-
-
Frezzetti, D.1
-
66
-
-
67749110399
-
Mir-21 is an EGFR-regulated antiapoptotic factor in lung cancer in never-smokers
-
PMID: 19597153 PMCID 2715493
-
Seike M et al (2009) MiR-21 is an EGFR-regulated antiapoptotic factor in lung cancer in never-smokers Proc Natl Acad Sci U S A 106(29) 12085-90 DOI: 10.1073/pnas.0905234106 PMID: 19597153 PMCID: 2715493
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.29
, pp. 12085-12090
-
-
Seike, M.1
-
67
-
-
84892888388
-
Mir-21 overexpression is associated with acquired resistance of EGFR-tki in non-small cell lung cancer
-
Li B et al (2014) MiR-21 overexpression is associated with acquired resistance of EGFR-TKI in non-small cell lung cancer Lung Cancer 83(2) 146-53 DOI: 10.1016/j.lungcan.2013.11.003
-
(2014)
Lung Cancer
, vol.83
, Issue.2
, pp. 146-153
-
-
Li, B.1
-
68
-
-
84904806763
-
Alteration in mir-21/pten expression modulates gefitinib resistance in non-small
-
PMID: 25058005 PMCID 4110008
-
Shen H et al (2014) Alteration in Mir-21/PTEN Expression Modulates Gefitinib Resistance in Non-Small Cell Lung Cancer PLoS One 9(7) e103305 DOI: 10.1371/journal.pone.0103305 PMID: 25058005 PMCID: 4110008
-
(2014)
Cell Lung Cancer PLoS One
, vol.9
, Issue.7
, pp. e103305
-
-
Shen, H.1
-
69
-
-
84864865233
-
Microrna-214 regulates the acquired resistance to gefitinib via the pten/akt pathway in EGFR-mutant cell lines asian pac
-
PMID: 22502680
-
Wang YS et al (2012) MicroRNA-214 regulates the acquired resistance to gefitinib via the PTEN/AKT pathway in EGFR-mutant cell lines Asian Pac J Cancer Prev 13(1) 255-60 DOI: 10.7314/APJCP.2012.13.1.255 PMID: 22502680
-
(2012)
J Cancer Prev
, vol.13
, Issue.1
, pp. 255-260
-
-
Wang, Y.S.1
-
70
-
-
84864976790
-
Mir-23a regulates tgf-beta-induced epithelial-mesenchymal transition by targeting e-cadherin in lung cancer cells
-
PMID: 22752005 PMCID 3582905
-
Cao M et al (2012) MiR-23a regulates TGF-beta-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells Int J Oncol 41(3) 869-75 PMID: 22752005 PMCID: 3582905
-
(2012)
Int J Oncol
, vol.41
, Issue.3
, pp. 869-875
-
-
Cao, M.1
-
71
-
-
84904265894
-
The tgf?-mir200-mig6 pathway orchestrates the emt-Associated kinase switch that induces resistance to EGFR inhibitors
-
PMID: 24830724 PMCID 4122100
-
Izumchenko E et al (2014) The TGF?-miR200-MIG6 pathway orchestrates the EMT-Associated kinase switch that induces resistance to EGFR inhibitors Cancer Res 74(14) 3995-4005 DOI: 10.1158/0008-5472.CAN-14-0110 PMID: 24830724 PMCID: 4122100
-
(2014)
Cancer Res
, vol.74
, Issue.14
, pp. 3995-4005
-
-
Izumchenko, E.1
-
72
-
-
84894206438
-
Mir-134/487b/655 cluster regulates tgf-?-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting magi2 in lung adenocarcinoma cells
-
MCT-13-0448
-
Kitamura K et al (2014) MiR-134/487b/655 cluster regulates TGF-?-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells Mol Cancer Ther 13(2) 444-53 DOI: 10.1158/1535-7163. MCT-13-0448
-
(2014)
Mol Cancer Ther
, vol.13
, Issue.2
, pp. 444-453
-
-
Kitamura, K.1
-
73
-
-
35648953299
-
Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires bim and can be enhanced by bh3 mimetics
-
PMID: 17973573 PMCID 2043013
-
Cragg MS et al (2007) Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics PLoS Med 4(10) 1681-9 DOI: 10.1371/journal.pmed.0040316 PMID: 17973573 PMCID: 2043013
-
(2007)
PLoS Med
, vol.4
, Issue.10
, pp. 1681-1689
-
-
Cragg, M.S.1
-
74
-
-
84855543629
-
EGFR and met receptor tyrosine kinase-Altered microrna expression induces tumorigenesis and gefitinib resistance in lung cancers
-
PMID: 22157681 PMCID 3467100
-
Garofalo M et al (2011) EGFR and MET receptor tyrosine kinase-Altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers Nat Med 18(1) 74-82 PMID: 22157681 PMCID: 3467100
-
(2011)
Nat Med
, vol.18
, Issue.1
, pp. 74-82
-
-
Garofalo, M.1
-
75
-
-
84896884571
-
Mir-130a overcomes gefitinib resistance by targeting met in non-small cell lung cancer cell lines asian pac
-
PMID: 24606471
-
Zhou YM, Liu J and Sun W (2014) MiR-130a Overcomes Gefitinib Resistance by Targeting Met in Non-Small Cell Lung Cancer Cell Lines Asian Pac J Cancer Prev 15(3) 1391-6 DOI: 10.7314/APJCP.2014.15.3.1391 PMID: 24606471
-
(2014)
J Cancer Prev
, vol.15
, Issue.3
, pp. 1391-1396
-
-
Zhou, Y.M.1
Liu, J.2
Sun, W.3
-
76
-
-
84856533765
-
Mir-130a targets met and induces trail-sensitivity in NSCLC by downregulating mir-221 and 222
-
Acunzo M et al (2012) miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222 Oncogene 31(5) 634-42
-
(2012)
Oncogene
, vol.31
, Issue.5
, pp. 634-642
-
-
Acunzo, M.1
-
77
-
-
70949104622
-
Mir-221&222 regulate trail resistance and enhance tumorigenicity through pten and timp3 downregulation
-
PMID: 19962668 PMCID 2796583
-
Garofalo M et al (2009) miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation Cancer Cell 16(6) 498-509 DOI: 10.1016/j.ccr.2009.10.014 PMID: 19962668 PMCID: 2796583
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 498-509
-
-
Garofalo, M.1
-
78
-
-
84904765311
-
Microrna-34a overcomes hgf-mediated gefitinib resistance in EGFR mutant lung cancer cells partly by targeting met
-
PMID: 24983493
-
Zhou JY et al (2014) MicroRNA-34a overcomes HGF-mediated gefitinib resistance in EGFR mutant lung cancer cells partly by targeting MET Cancer Lett 351(2) 265-71 DOI: 10.1016/j.canlet.2014.06.010 PMID: 24983493
-
(2014)
Cancer Lett
, vol.351
, Issue.2
, pp. 265-271
-
-
Zhou, J.Y.1
-
79
-
-
84891340358
-
Therapeutic resistance in cancer: Microrna regulation of EGFR signaling networks
-
PMID: 24349829 PMCID 3860350
-
Gomez GG, Wykosky J and Zanca C (2013) Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks Cancer Biol Med 10(4) 192-205 PMID: 24349829 PMCID: 3860350
-
(2013)
Cancer Biol Med
, vol.10
, Issue.4
, pp. 192-205
-
-
Gomez, G.G.1
Wykosky, J.2
Zanca, C.3
-
80
-
-
34249822779
-
Transcriptional activation of mir-34a contributes to p53-mediated apoptosis
-
PMID: 17540598
-
Raver-Shapira N et al (2007) Transcriptional activation of miR-34a contributes to p53-mediated apoptosis Mol Cell 26(5) 731-43 DOI: 10.1016/j.molcel.2007.05.017 PMID: 17540598
-
(2007)
Mol Cell
, vol.26
, Issue.5
, pp. 731-743
-
-
Raver-Shapira, N.1
-
81
-
-
84868254278
-
Mirna-34 prevents cancer initiation and progression in a therapeutically resistant k-ras and p53-induced mouse model of lung adenocarcinoma
-
PMID: 22964582 PMCID 3488137
-
Kasinski AL and Slack FJ (2012) miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma Cancer Res 72(21) 5576-87 DOI: 10.1158/0008-5472.CAN-12-2001 PMID: 22964582 PMCID: 3488137
-
(2012)
Cancer Res
, vol.72
, Issue.21
, pp. 5576-5587
-
-
Kasinski, A.L.1
Slack, F.J.2
-
82
-
-
84895866286
-
In-depth analysis shows synergy between erlotinib and mir-34a
-
PMID: 24551227 PMCID 3925231
-
Zhao J, Kelnar K and Bader AG (2014) In-depth analysis shows synergy between erlotinib and miR-34a PLoS One 9(2) e89105 DOI: 10.1371/journal.pone.0089105 PMID: 24551227 PMCID: 3925231
-
(2014)
PLoS One
, vol.9
, Issue.2
, pp. e89105
-
-
Zhao, J.1
Kelnar, K.2
Bader, A.G.3
-
83
-
-
79959673368
-
Regulation of axl receptor tyrosine kinase expression by mir-34a and mir-199a/b in solid cancer
-
PMID: 21317930
-
Mudduluru G et al (2011) Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer Oncogene 30(25) 2888-99 DOI: 10.1038/onc.2011.13 PMID: 21317930
-
(2011)
Oncogene
, vol.30
, Issue.25
, pp. 2888-2899
-
-
Mudduluru, G.1
-
84
-
-
80051613002
-
Genome-wide characterization of mir-34a induced changes in protein and mRNA expression by a combined pulsed silac and microarray analysis
-
PMID: 21566225 PMCID 3149097
-
Kaller M et al (2011) Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis Mol Cell Proteomics 10(8) M111.010462 DOI: 10.1074/mcp.M111.010462 PMID: 21566225 PMCID: 3149097
-
(2011)
Mol Cell Proteomics
, vol.10
, Issue.8
, pp. M111010462
-
-
Kaller, M.1
-
85
-
-
84898002784
-
Mir-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating g protein-coupled receptor 124
-
PMID: 24582749
-
Gao Y et al (2014) miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124 Biochem Biophys Res Commun 446(1) 179-86 DOI: 10.1016/j.bbrc.2014.02.073 PMID: 24582749
-
(2014)
Biochem Biophys Res Commun
, vol.446
, Issue.1
, pp. 179-186
-
-
Gao, Y.1
-
86
-
-
80052698948
-
Liposomal delivery of microrna-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells
-
PMID: 21712475
-
Rai K et al (2011) Liposomal delivery of MicroRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells Mol Cancer Ther 10(9) 1720-7 DOI: 10.1158/1535-7163.MCT-11-0220 PMID: 21712475
-
(2011)
Mol Cancer Ther
, vol.10
, Issue.9
, pp. 1720-1727
-
-
Rai, K.1
-
87
-
-
84898636549
-
Microrna-147 induces a mesenchymal-to-epithelial transition (met) and reverses EGFR inhibitor resistance
-
PMID: 24454732 PMCID 3893127
-
Lee CG et al (2014) MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance PLoS One 9(1) e84597 DOI: 10.1371/journal.pone.0084597 PMID: 24454732 PMCID: 3893127
-
(2014)
PLoS One
, vol.9
, Issue.1
, pp. e84597
-
-
Lee, C.G.1
-
88
-
-
84939882280
-
Suppression of dicer increases sensitivity to gefitinib in human lung cancer cells
-
Chen JC et al (2014) Suppression of dicer increases sensitivity to gefitinib in human lung cancer cells Ann Surg Oncol 21(Suppl 4) 555-63 DOI: 10.1245/s10434-014-3673-y
-
(2014)
Ann Surg Oncol
, vol.21
, pp. 555-563
-
-
Chen, J.C.1
-
89
-
-
84928405843
-
Non-coding rnas in lung cancer
-
Ricciuti B et al (2014) Non-coding RNAs in lung cancer Oncoscience 1(11) 674-705
-
(2014)
Oncoscience
, vol.1
, Issue.11
, pp. 674-705
-
-
Ricciuti, B.1
|