메뉴 건너뛰기




Volumn 35, Issue 2, 2016, Pages 219-226

Vaccine pipeline has grown during the past two decades with more early-stage trials from small and medium-size companies

Author keywords

[No Author keywords available]

Indexed keywords

VACCINE;

EID: 84958672783     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2015.1073     Document Type: Article
Times cited : (12)

References (32)
  • 1
    • 84929898368 scopus 로고    scopus 로고
    • Geneva: World Health Organization, [cited 2015 Dec 16]
    • Strategic Advisory Group of Experts on Immunization. 2014 assessment report of the Global Vaccine Action Plan [Internet]. Geneva: World Health Organization; 2014 [cited 2015 Dec 16]. Available from: http://www.who.int/immunization/policy/sage/en/
    • (2014) 2014 assessment report of the Global Vaccine Action Plan
  • 2
    • 79959510824 scopus 로고    scopus 로고
    • Estimated economic benefits during the "Decade of Vaccines" include treatment savings, gains in labor productivity
    • Stack ML, Ozawa S, Bishai DM, Mirelman A, Tam Y, Niessen L, et al. Estimated economic benefits during the "Decade of Vaccines" include treatment savings, gains in labor productivity. Health Aff (Millwood). 2011;30(6):1021-8.
    • (2011) Health Aff (Millwood) , vol.30 , Issue.6 , pp. 1021-1028
    • Stack, M.L.1    Ozawa, S.2    Bishai, D.M.3    Mirelman, A.4    Tam, Y.5    Niessen, L.6
  • 3
    • 79959501432 scopus 로고    scopus 로고
    • During the "Decade of Vaccines, " the lives of 6.4 million children valued at $231 billion could be saved
    • Ozawa S, Stack ML, Bishai DM, Mirelman A, Friberg IK, Niessen L, et al. During the "Decade of Vaccines, " the lives of 6.4 million children valued at $231 billion could be saved. Health Aff (Millwood). 2011; 30(6):1010-20.
    • (2011) Health Aff (Millwood) , vol.30 , Issue.6 , pp. 1010-1020
    • Ozawa, S.1    Stack, M.L.2    Bishai, D.M.3    Mirelman, A.4    Friberg, I.K.5    Niessen, L.6
  • 4
    • 77952226221 scopus 로고    scopus 로고
    • Why we don't have an HIV vaccine, and how we can develop one
    • Harris JE.Why we don't have an HIV vaccine, and how we can develop one. Health Aff (Millwood). 2009; 28(6):1642-54.
    • (2009) Health Aff (Millwood) , vol.28 , Issue.6 , pp. 1642-1654
    • Harris, J.E.1
  • 5
    • 79959491421 scopus 로고    scopus 로고
    • The challenges of developing new tuberculosis vaccines
    • Barker LF, Leadman AE, Clagett B. The challenges of developing new tuberculosis vaccines. Health Aff (Millwood). 2011;30(6):1073-9.
    • (2011) Health Aff (Millwood) , vol.30 , Issue.6 , pp. 1073-1079
    • Barker, L.F.1    Leadman, A.E.2    Clagett, B.3
  • 6
    • 85003055643 scopus 로고    scopus 로고
    • A new wave of vaccines for non-communicable diseases: what are the regulatory challenges?
    • Darrow JJ, Kesselheim AS. A new wave of vaccines for non-communicable diseases: what are the regulatory challenges? Food Drug Law J. 2015;70(2):243-58.
    • (2015) Food Drug Law J , vol.70 , Issue.2 , pp. 243-258
    • Darrow, J.J.1    Kesselheim, A.S.2
  • 7
    • 84932617711 scopus 로고    scopus 로고
    • The 21st Century Cures Act-will it take us back in time?
    • Avorn J, Kesselheim AS. The 21st Century Cures Act-will it take us back in time? N Engl J Med. 2015; 372(26):2473-5.
    • (2015) N Engl J Med , vol.372 , Issue.26 , pp. 2473-2475
    • Avorn, J.1    Kesselheim, A.S.2
  • 8
    • 20044388955 scopus 로고    scopus 로고
    • Why are pharmaceutical companies gradually abandoning vaccines?
    • Offit PA.Why are pharmaceutical companies gradually abandoning vaccines? Health Aff (Millwood). 2005;24(3):622-30.
    • (2005) Health Aff (Millwood) , vol.24 , Issue.3 , pp. 622-630
    • Offit, P.A.1
  • 9
    • 20044366421 scopus 로고    scopus 로고
    • Factors affecting U.S. manufacturers' decisions to produce vaccines
    • Coleman MS, Sangrujee N, Zhou F, Chu S. Factors affecting U.S. manufacturers' decisions to produce vaccines. Health Aff (Millwood). 2005; 24(3):635-42.
    • (2005) Health Aff (Millwood) , vol.24 , Issue.3 , pp. 635-642
    • Coleman, M.S.1    Sangrujee, N.2    Zhou, F.3    Chu, S.4
  • 10
    • 20044370319 scopus 로고    scopus 로고
    • Overcoming economic barriers to the optimal use of vaccines
    • Lieu TA, McGuire TG, Hinman AR. Overcoming economic barriers to the optimal use of vaccines. Health Aff (Millwood). 2005;24(3):666-79.
    • (2005) Health Aff (Millwood) , vol.24 , Issue.3 , pp. 666-679
    • Lieu, T.A.1    McGuire, T.G.2    Hinman, A.R.3
  • 11
    • 79959492084 scopus 로고    scopus 로고
    • Vaccines as a global imperative-a business perspective
    • Stéphenne J. Vaccines as a global imperative-a business perspective. Health Aff (Millwood). 2011;30(6): 1042-8.
    • (2011) Health Aff (Millwood) , vol.30 , Issue.6 , pp. 1042-1048
    • Stéphenne, J.1
  • 12
    • 84901603869 scopus 로고    scopus 로고
    • Target small firms for antibiotic innovation
    • Hwang TJ, Carpenter D, Kesselheim AS. Target small firms for antibiotic innovation. Science. 2014; 344(6187):967-9.
    • (2014) Science , vol.344 , Issue.6187 , pp. 967-969
    • Hwang, T.J.1    Carpenter, D.2    Kesselheim, A.S.3
  • 14
    • 81955167436 scopus 로고    scopus 로고
    • Failure-to-success ratios, transition probabilities, and phase lengths for prophylactic vaccines versus other pharmaceuticals in the development pipeline
    • Davis MM, Butchart AT, Wheeler JR, Coleman MS, Singer DC, Freed GL. Failure-to-success ratios, transition probabilities, and phase lengths for prophylactic vaccines versus other pharmaceuticals in the development pipeline. Vaccine. 2011;29(51):9414-6.
    • (2011) Vaccine , vol.29 , Issue.51 , pp. 9414-9416
    • Davis, M.M.1    Butchart, A.T.2    Wheeler, J.R.3    Coleman, M.S.4    Singer, D.C.5    Freed, G.L.6
  • 15
    • 33645675960 scopus 로고    scopus 로고
    • Estimating the cost of new drug development: is it really 802 million dollars?
    • Adams CP, Brantner VV. Estimating the cost of new drug development: is it really 802 million dollars? Health Aff (Millwood). 2006;25(2):420-8.
    • (2006) Health Aff (Millwood) , vol.25 , Issue.2 , pp. 420-428
    • Adams, C.P.1    Brantner, V.V.2
  • 16
    • 84922756124 scopus 로고    scopus 로고
    • Improving pharmaceutical innovation by building a more comprehensive database on drug development and use
    • Daniel GW, Cazé A, Romine MH, Audibert C, Leff JS, McClellan MB. Improving pharmaceutical innovation by building a more comprehensive database on drug development and use. Health Aff (Millwood). 2015;34(2):319-27.
    • (2015) Health Aff (Millwood) , vol.34 , Issue.2 , pp. 319-327
    • Daniel, G.W.1    Cazé, A.2    Romine, M.H.3    Audibert, C.4    Leff, J.S.5    McClellan, M.B.6
  • 17
    • 84886732585 scopus 로고    scopus 로고
    • Silver Spring (MD): FDA; [last updated 2010 Feb 22; cited 2015 Dec 16]
    • Food and Drug Administration. Biological approvals by year [Internet]. Silver Spring (MD): FDA; [last updated 2010 Feb 22; cited 2015 Dec 16]. Available from: http://www.fda.gov/BiologicsBloodVaccines/DevelopmentApprovalProcess/BiologicalApprovalsbyYear/default.htm
    • Biological approvals by year
  • 18
    • 44949230030 scopus 로고    scopus 로고
    • Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial
    • Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, et al. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet. 2008;371(9629): 2019-25.
    • (2008) Lancet , vol.371 , Issue.9629 , pp. 2019-2025
    • Frech, S.A.1    Dupont, H.L.2    Bourgeois, A.L.3    McKenzie, R.4    Belkind-Gerson, J.5    Figueroa, J.F.6
  • 19
    • 84894294907 scopus 로고    scopus 로고
    • Efficacy and safety of a patch vaccine containing heat-labile toxin fromEscherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala
    • Behrens RH, Cramer JP, Jelinek T, Shaw H, von Sonnenburg F, Wilbraham D, et al. Efficacy and safety of a patch vaccine containing heat-labile toxin fromEscherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala. Lancet Infect Dis. 2014;14(3): 197-204.
    • (2014) Lancet Infect Dis , vol.14 , Issue.3 , pp. 197-204
    • Behrens, R.H.1    Cramer, J.P.2    Jelinek, T.3    Shaw, H.4    von Sonnenburg, F.5    Wilbraham, D.6
  • 24
    • 79955133873 scopus 로고    scopus 로고
    • Safety, supply, and suits-litigation and the vaccine industry
    • Kesselheim A. Safety, supply, and suits-litigation and the vaccine industry. N Engl J Med. 2011;364(16): 1485-7.
    • (2011) N Engl J Med , vol.364 , Issue.16 , pp. 1485-1487
    • Kesselheim, A.1
  • 25
    • 84922722479 scopus 로고    scopus 로고
    • Biosimilar competition in the United States: statutory incentives, payers, and pharmacy benefit managers
    • Falit BP, Singh SC, Brennan TA. Biosimilar competition in the United States: statutory incentives, payers, and pharmacy benefit managers. Health Aff (Millwood). 2015;34(2): 294-301.
    • (2015) Health Aff (Millwood) , vol.34 , Issue.2 , pp. 294-301
    • Falit, B.P.1    Singh, S.C.2    Brennan, T.A.3
  • 27
    • 80052461378 scopus 로고    scopus 로고
    • Vaccines and future global health needs
    • Nossal GJV. Vaccines and future global health needs. Philos Trans R Soc Lond B Biol Sci. 2011;366(1579): 2833-40.
    • (2011) Philos Trans R Soc Lond B Biol Sci , vol.366 , Issue.1579 , pp. 2833-2840
    • Nossal, G.J.V.1
  • 28
    • 84947731081 scopus 로고    scopus 로고
    • Vaccine-resistant malaria
    • Plowe CV. Vaccine-resistant malaria. N Engl J Med. 2015;373(21):2082-3.
    • (2015) N Engl J Med , vol.373 , Issue.21 , pp. 2082-2083
    • Plowe, C.V.1
  • 29
    • 33750862932 scopus 로고    scopus 로고
    • Vaccine manufacturing: challenges and solutions
    • Ulmer JB, Valley U, Rappuoli R. Vaccine manufacturing: challenges and solutions. Nat Biotechnol. 2006;24(11):1377-83.
    • (2006) Nat Biotechnol , vol.24 , Issue.11 , pp. 1377-1383
    • Ulmer, J.B.1    Valley, U.2    Rappuoli, R.3
  • 30
    • 84958608950 scopus 로고    scopus 로고
    • White House Blog [blog on the Internet]. Sep 18 [cited 2015 Dec 16]
    • White House. New executive actions to combat antibiotic resistance and protect public health. White House Blog [blog on the Internet]. 2014 Sep 18 [cited 2015 Dec 16]. Available from: https://www.whitehouse.gov/blog/2014/09/18/new-executiveactions-combat-antibioticresistance-and-protect-public-health
    • (2014) New executive actions to combat antibiotic resistance and protect public health
  • 31
    • 84937857841 scopus 로고    scopus 로고
    • Establishing a global vaccine-development fund
    • Plotkin SA, Mahmoud AA, Farrar J. Establishing a global vaccine-development fund. N Engl J Med. 2015; 373(4):297-300.
    • (2015) N Engl J Med , vol.373 , Issue.4 , pp. 297-300
    • Plotkin, S.A.1    Mahmoud, A.A.2    Farrar, J.3
  • 32
    • 84907960454 scopus 로고    scopus 로고
    • Global financing and long-term technical assistance for multidrug-resistant tuberculosis: scaling up access to treatment
    • Hwang TJ, Keshavjee S. Global financing and long-term technical assistance for multidrug-resistant tuberculosis: scaling up access to treatment. PLoS Med. 2014;11(9): e1001738.
    • (2014) PLoS Med , vol.11 , Issue.9
    • Hwang, T.J.1    Keshavjee, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.