Chronic non-cancer pain and the epidemic prescription of opioids in the Danish population: Trends from 2000 to 2013

Acta Anaesthesiologica Scandinavica

Volumn 60, Issue 5, 2016, Pages 623-633

  Birke, H ^a   Kurita, G P ^a   Sjogren P ^a   Hojsted J ^a   Simonsen, M K ^b   Juel, K ^c   Ekholm, O ^c  

^a Rigshospitalet   (Denmark)

^b FINSEN LABORATORY   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE; BUPRENORPHINE; CODEINE; DEXTROPROPOXYPHENE; FENTANYL; HYDROMORPHONE; KETOBEMIDONE; MORPHINE; OPIATE; OXYCODONE; PETHIDINE; SPASMOLYTIC AGENT; TAPENTADOL; TRAMADOL; BENZODIAZEPINE DERIVATIVE; NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ARTICLE; CHRONIC NON CANCER PAIN; CHRONIC PAIN; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DENMARK; DRUG DOSE REDUCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; ADULT; AGE; AGED; COHORT ANALYSIS; COMBINATION DRUG THERAPY; DRUG UTILIZATION; MIDDLE AGED; OPIOID-RELATED DISORDERS; POPULATION; SEX DIFFERENCE; SOCIOECONOMICS; STATISTICS AND NUMERICAL DATA; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; BENZODIAZEPINES; CHRONIC PAIN; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DENMARK; DRUG PRESCRIPTIONS; DRUG THERAPY, COMBINATION; DRUG UTILIZATION; FEMALE; HUMANS; MALE; MIDDLE AGED; OPIOID-RELATED DISORDERS; POPULATION; SEX FACTORS; SOCIOECONOMIC FACTORS; SURVEYS AND QUESTIONNAIRES; YOUNG ADULT;

EID: 84958654993     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12700     Document Type: Article

References (54)

1. Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D,. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain 2006; 10: 287-333.
2. De Conno F, Ripamonti C, Brunelli C,. Opioid purchases and expenditure in nine western European countries: 'are we killing off morphine?'. Palliat Med 2005; 19: 179-84.
3. Garcia DPJ, Carvajal A, Viloria JM, Velasco A, Garcia DPV,. Trends in the consumption of opioid analgesics in Spain. Higher increases as fentanyl replaces morphine. Eur J Clin Pharmacol 2008; 64: 411-5.
4. Kalso E, Edwards JE, Moore RA, McQuay HJ,. Opioids in chronic non-cancer pain: systematic review of efficacy and safety. Pain 2004; 112: 372-80.
5. Toblin RL, Mack KA, Perveen G, Paulozzi LJ,. A population-based survey of chronic pain and its treatment with prescription drugs. Pain 2011; 152: 1249-55.
6. Kurita GP, Sjøgren P, Juel K, Højsted J, Ekholm O,. The burden of chronic pain: a cross-sectional survey focusing on diseases, immigration, and opioid use. Pain 2012; 153: 2332-8.
7. Von Korff M, Kolodny A, Deyo RA, Chou R,. Long-term opioid therapy reconsidered. Ann Intern Med 2011; 155: 25-8.
8. Jarlbaek L, Kehlet H, Sjøgren P,. The licit opioid consumption in Denmark. Ugeskr Laeger 2010; 15: 3173-8.
9. Kahan M, Mailis-Gagnon A, Wilson L, Srivastava A,. Canadian guideline for safe and effective use of opioids for chronic noncancer pain. Clinical summary for family physicians. Part 1: general population. Can Fam Physician 2011; 57: 1257-66.
10. Manchikanti L, Abdi S, Atluri S, Balog CC, Benyamin RM, Boswell MV, Brown KR, Bruel BM, Bryce DA, Burks PA, Burton AW, Calodney AK, Caraway DL, Cash KA, Christo PJ, Damron KS, Datta S, Deer TR, Diwan S, Eriator I, Falco FJE, Fellows B, Geffert S, Gharibo CG, Glaser SE, Grider JS, Hameed H, Hameed M, Hansen H, Harned ME, Hayek SM, Helm S, Hirsch JA, Janata JW, Kaye AM, Kaye AD, Kloth DS, Koyyalagunta D, Lee M, Malla Y, Manchikanti KN, McManus CD, Pampati V, Parr AT, Pasupuleti R, Patel VB, Sehgal N, Silverman SM, Singh V, Smith HS, Snook LT, Solanki DR, Tracy DH, Vallejo R, Wargo BW,. American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: part 2-guidance. Pain Physician 2012; 15: 67-116.
11. Eriksen J, Sjøgren P, Bruera E, Ekholm O, Rasmussen NK,. Critical issues on opioids in chronic non-cancer pain: an epidemiological study. Pain 2006; 125: 172-9.
12. Furlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E,. Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. Can Med Assoc J 2006; 174: 1589-94.
13. Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM,. Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain 2010; 11: 807-29.
14. Højsted J, Ekholm O, Kurita GP, Juel K, Sjøgren P,. Addictive behaviors related to opioid use for chronic pain: a population-based study. Pain 2013; 154: 2677-83.
15. Højsted J, Nielsen PR, Guldstrand SK, Frich L, Sjøgren P,. Classification and identification of opioid addiction in chronic pain patients. Eur J Pain 2010; 14: 1014-20.
16. Sjøgren P, Grønbæk M, Peuckmann V, Ekholm O,. A population-based cohort study on chronic pain: the role of opioids. Clin J Pain 2010; 26: 763-9.
17. Rhodin A, Stridsberg M, Gordh T,. Opioid endocrinopathy: a clinical problem in patient with chronic pain and long-term oral opioid treatment. Clin J Pain 2010; 26: 374-80.
18. Svendsen K, Fredheim O, Romundstad P, Borchgrevink P, Skurveit S,. Persistent opioid use and socio-economic factors: a population-based study in Norway. Acta Anaesthesiol Scand 2014; 58: 437-45.
19. Melbye A, Svendsen K, Borchgrevink PC, Skurtveit S, Fredheim OM,. Concomitant medication among persistent opioid users with chronic nonmalignant pain. Acta Anaesthesiol Scand 2012; 56: 1267-76.
20. Morasco BJ, Duckart JP, Carr TP, Deyo RA, Dobscha SK,. Clinical characteristics of veterans prescribed high doses of opioid medications for chronic noncancer pain. Pain 2010; 151: 625-32.
21. Fredheim OM, Borchgrevink PC, Mahic M, Skurtveit S,. A pharmacoepidemiological cohort study of subjects starting strong opioids for nonmalignant pain: a study from the Norwegian Prescription Database. Pain 2013; 154: 2487-93.
22. Skurtveit S, Furu K, Bramness J, Selmer R, Tverdal A,. Benzodiazepines predict use of opioids - A follow-up study of 17,974 men and women. Pain Med 2010; 11: 805-14.
23. Davidsen M, Kjøller M, Helweg-Larsen K,. The Danish National Cohort Study (DANCOS). Scand J Public Health 2011; 39: 131-5.
24. Christensen AI, Ekholm O, Glümer C, Andreasen AH, Hvidberg MF, Kristensen PL, Larsen FB, Ortiz B, Juel K,. The Danish National Health Survey 2010. Study design and respondent characteristics. Scand J Public Health 2012; 40: 391-7.
25. Ekholm O, Hesse U, Davidsen M, Kjøller M,. The study design and characteristics of the Danish national health interview surveys. Scand J Public Health 2009; 37: 758-65.
26. Pedersen CB,. The Danish civil registration system. Scand J Public Health 2011; 39: 22-5.
27. Jensen VM, Rasmussen AW,. Danish education registers. Scand J Public Health 2011; 39: 91-4.
28. Kildemoes HW, Sorensen HT, Hallas J,. The Danish national prescription registry. Scand J Public Health 2011; 39: 38-41.
29. Ekholm O, Kurita GP, Højsted J, Juel K, Sjøgren P,. Chronic pain, opioid prescriptions, and mortality in Denmark: a population-based cohort study. Pain 2014; 155: 2486-90.
30. Svendsen K, Borchgrevink P, Fredheim O, Hamunen K, Mellbye A, Dale O,. Choosing the unit of mearsurement counts: the use of oral morphine equivalents in studies of opioid consumption is a useful addition to defined daily doses. Palliat Med 2011; 25: 725-32.
31. Dougherty L, Lister S,. The Royal Marsden Hospital manual of clinical nursing procedures, student edition, 8th edn. Chichester: Wiley-Blackwell, 2011.
32. Jensen-Dahm C, Gasse C, Astrup A, Mortensen PB, Waldemar G,. Frequent use of opioids in patients with dementia and nursing home residents - A study of the entire elderly population of Denmark. Alzheimers Dement 2015; 11: 691-9.
33. Fredheim OM, Mahic M, Skurtveit S, Dale O, Romundstad P, Borchgrevink P,. Chronic pain and use of opioids: a population-based pharmacoepidemiological study from the Norwegian Prescription Database and the Nord-Trøndelag Health Study. Pain 2014; 155: 1213-21.
34. Eriksen J, Ekholm O, Sjøgren P, Rasmussen NK,. Development of and recovery from long-term pain. A 6-year follow-up study of a cross-section of the adult Danish population. Pain 2004; 108: 154-62.
35. Nielsen CS,. Chronic pain is strongly associated with work disability. Scand J Pain 2013; 4: 180-1.
36. Gunnarsdottir S, Ward SE, Serlin RC,. A population based study of the prevalence of pain in Iceland. Scand J Pain 2010; 1: 151-7.
37. Rechel B, Mladovsky P, Ingleby D, Mackenbach JP, McKee M,. Migration and health in an increasingly diverse Europe. Lancet 2013; 381: 1235-45.
38. Marmot M, Allen J, Bell R, Bloomer E, Goldblatt P,. WHO European review of social determinants of health and the health divide. Lancet 2012; 380: 1011-29.
39. Blyth FM, March LM, Brnabic AJ, Jorm LR, Williamson M, Cousins MJ,. Chronic pain in Australia: a prevalence study. Pain 2001; 89: 127-34.
40. Eriksen J, Jensen MK, Sjøgren P, Ekholm O, Rasmussen NK,. Epidemiology of chronic non-malignant pain in Denmark. Pain 2003; 106: 221-8.
41. Schopflocher D, Taenzer P, Jovey R,. The prevalence of chronic pain in Canada. Pain Res Manage 2011; 16: 445-50.
42. Yates P,. Pain: the views of elderly people living in long-term residential care settings. J Adv Nurs 1995; 21: 667-74.
43. Fisher SE,. Obtaining self-report data from cognitively impaired elders: methodological issues and clinical implications for nursing home pain assessment. Gerontologist 2006; 46: 81-8.
44. Bertakis KD, Azari R, Helms LJ, Callahan EJ, Robbins JA,. Gender differences in the utilization of health care services. J Fam Pract 2000; 49: 147-52.
45. Carretero MT, Calderón-Larrañaga A, Poblador-Plou B, Prados-Torres A,. Primary health care use from the perspective of gender and morbidity burden. BMC Womens Health 2014; 14: 145-51.
46. Breivik H,. Whether the weather influences pain: high prevalence of chronic pain in Iceland and Norway: common genes? Or lack of sunshine and vitamin D? Scand J Pain 2010; 1: 149-50.
47. Ge HY, Madeleine P, Cairns BE, Arendt-Nielsen L,. Hypoalgesia in the referred pain areas after bilateral injections of hypertonic saline into the trapezius muscles of men and women: a potential experimental model of gender-specific differences. Clin J Pain 2006; 22: 37-44.
48. Rollman GB, Lautenbacher S, Jones KS,. Sex and gender differences in responses to experimentally induces pain in humans. In:, Fillingham RB, ed. Sex, gender and pain. Progress in pain research and management. Seattle: IASP Press, 2000: 165-90.
49. Fillingima RB, Nessb TJ,. Sex-related hormonal influences on pain and analgesic responses. Neurosci Biobehav Rev 2000; 24: 485-501.
50. Greenspan JD, Craft RM, LeResche L, Arendt-Nielsen L, Berkley KJ, Fillingim RB, Gold MS, Holdcroft A, Lautenbacher S, Mayer EA, Mogil JS, Murphy AZ, Traub RJ,. Consensus working group of the sex, gender, and pain SIG of the IASP. Pain 2007; 132: 26-45.
51. Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL,. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain 2009; 10: 447-85.
52. Chou R, Turner JA, Devine EB, Hansen RN, Sullivan SD, Blazina I, Dana T, Bougatsos C, Deyo RA,. The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institute of Health Pathways to Prevention Workshop. Ann Intern Med 2015; 162: 276-86.
53. Sehgal N, Manchikanti L, Smith HS,. Prescription opioid abuse in chronic pain: a review of opioid abuse predictors and strategies to curb opioid abuse. Pain Physician 2012; 15: 67-92.
54. Graziottin A, Gardner-Nix J, Stumpf M, Berliner MN,. Opioids: how to improve compliance and adherence. Pain Pract 2011; 11: 574-81.