Prevention of tumor formation by latent gammaherpesvirus infection

PLoS ONE

Volumn 10, Issue 12, 2015, Pages

  Raffegerst, S ^a,b   Steer, B ^a   Hohloch, M ^a   Adler, H ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b MediGene AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CONTROLLED STUDY; ENDOGENOUS RETROVIRUS; GAMMAHERPESVIRINAE; HEMATOLOGIC MALIGNANCY; HERPES VIRUS INFECTION; HYPOSPLENISM; LATENT VIRUS INFECTION; MOUSE; NONHUMAN; OVERALL SURVIVAL; SPLEEN DISEASE; WILD TYPE; ANIMAL; BIOSYNTHESIS; CELL LINE; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; RETROVIRIDAE; RHADINOVIRUS; SURVIVAL ANALYSIS; T LYMPHOCYTE; VIRUS LATENCY;

ANIMALS; CARCINOGENESIS; CELL LINE; HOST-PATHOGEN INTERACTIONS; INTERFERON-GAMMA; MICE; RETROVIRIDAE; RHADINOVIRUS; SURVIVAL ANALYSIS; T-LYMPHOCYTES; VIRUS LATENCY;

EID: 84958225164     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0145678     Document Type: Article

References (24)

1. Schulz TF. Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). J Gen Virol. 1998; 79:1573-1591. PMID: 9680119
2. Rickinson AB, Kieff E. Epstein-Barr Virus. In: Knipe DM, Howley PM, Griffin DE, Martin MA, Lamb RA et al., editors. Fields-Virology. Philadelphia: Lippincott Williams & Wilkins. 2001; pp. 2575-2627.
3. Virgin HW, Wherry EJ, Ahmed R. Redefining chronic viral infection. Cell. 2009; 138:30-50. doi: 10. 1016/j.cell.2009.06.036 PMID: 19596234
4. Virgin HW. The virome in mammalian physiology and disease. Cell. 2014; 157:142-150. doi: 10.1016/ j.cell.2014.02.032 PMID: 24679532
5. Barton E, Mandal P, Speck SH. Pathogenesis and Host Control of Gammaherpesviruses: Lessons from the Mouse. Annu Rev Immunol. 2011; 29:351-397. doi: 10.1146/annurev-immunol-072710-081639 PMID: 21219186
6. Barton ES, White DW, Cathelyn JS, Brett-McClellan KA, Engle M, Diamond MS et al. Herpesvirus latency confers symbiotic protection from bacterial infection. Nature. 2007; 447:326-329. PMID: 17507983
7. Saito F, Ito T, Connett JM, Schaller MA, Carson WF, Hogaboam CM et al. MHV68 latency modulates the host immune response to influenza A virus. Inflammation. 2013; 36:1295-1303. doi: 10.1007/ s10753-013-9668-1 PMID: 23807051
8. White DW, Keppel CR, Schneider SE, Reese TA, Coder J, Payton JE et al. Latent herpesvirus infection arms NK cells. Blood. 2010; 115:4377-4383. doi: 10.1182/blood-2009-09-245464 PMID: 20139098
9. Yager EJ, Szaba FM, Kummer LW, Lanzer KG, Burkum CE, Smiley ST et al. gamma-Herpesvirusinduced protection against bacterial infection is transient. Viral Immunol. 2009; 22:67-72. doi: 10.1089/ vim.2008.0086 PMID: 19210230
10. Raffegerst SH, Hoelzlwimmer G, Kunder S, Mysliwietz J, Quintanilla-Martinez L, Schendel DJ. Diverse hematological malignancies including Hodgkin-like lymphomas develop in chimeric MHC class II transgenic mice. PLoS ONE. 2009; 4:e8539. doi: 10.1371/journal.pone.0008539 PMID: 20046882
11. Adler H, Messerle M, Wagner M, Koszinowski UH. Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J Virol. 2000; 74:6964-6974. PMID: 10888635
12. Ito K, Bian HJ, Molina M, Han J, Magram J, Saar E et al. HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis. J Exp Med. 1996; 183:2635-2644. PMID: 8676084
13. Fowler P, Marques S, Simas JP, Efstathiou S. ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency. J Gen Virol. 2003; 84:3405-3416. PMID: 14645921
14. Moorman NJ, Willer DO, Speck SH. The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency. J Virol. 2003; 77:10295-10303. PMID: 12970414
15. Lisco A, Grivel JC, Biancotto A, Vanpouille C, Origgi F, Malnati MS et al. Viral interactions in human lymphoid tissue: Human herpesvirus 7 suppresses the replication of CCR5-tropic human immunodeficiency virus type 1 via CD4 modulation. J Virol. 2007; 81:708-717. PMID: 17065205
16. Crowley RW, Secchiero P, Zella D, Cara A, Gallo RC, Lusso P. Interference between human herpesvirus 7 and HIV-1 in mononuclear phagocytes. J Immunol. 1996; 156:2004-2008. PMID: 8596056
17. Raymond AD, Hasham M, Tsygankov AY, Henderson EE. Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions. Curr HIV Res. 2007; 5:79-86. PMID: 17266559
18. Yu P, Lubben W, Slomka H, Gebler J, Konert M, Cai C et al. Nucleic acid-sensing Toll-like receptors are essential for the control of endogenous retrovirus viremia and ERV-induced tumors. Immunity. 2012; 37:867-879. doi: 10.1016/j.immuni.2012.07.018 PMID: 23142781
19. Guggemoos S, Hangel D, Hamm S, Heit A, Bauer S, Adler H. TLR9 Contributes to Antiviral Immunity during Gammaherpesvirus Infection. J Immunol. 2008; 180:438-443. PMID: 18097045
20. Ebrahimi B, Dutia BM, Brownstein DG, Nash AA. Murine gammaherpesvirus-68 infection causes multiorgan fibrosis and alters leukocyte trafficking in interferon-γ receptor knockout mice. Am J Pathol. 2001; 158:2117-2125. PMID: 11395389
21. Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, Van Dyk LF et al. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proc Natl Acad Sci U S A. 2012; 109:E1092-E1100. doi: 10.1073/pnas.1203019109 PMID: 22474381
22. Chauhan VS, Nelson DA, Roy LD, Mukherjee P, Bost KL. Exacerbated metastatic disease in a mouse mammary tumor model following latent gammaherpesvirus infection. Infect Agent Cancer. 2012; 7:11-17. doi: 10.1186/1750-9378-7-11 PMID: 22642913
23. Auger S, Orsini M, Ceballos P, Fegueux N, Kanouni T, Caumes B et al. Controlled Epstein-Barr virus reactivation after allogeneic transplantation is associated with improved survival. Eur J Haematol. 2014; 92:421-428. doi: 10.1111/ejh.12260 PMID: 24400833
24. Saghafian-Hedengren S, Sverremark-Ekstrom E, Linde A, Lilja G, Nilsson C. Early-life EBV infection protects against persistent IgE sensitization. J Allergy Clin Immunol. 2010; 125:433-438. doi: 10.1016/ j.jaci.2009.09.033 PMID: 19963258