Hyperuricemia induces hypertension through activation of renal epithelial sodium channel (ENaC)

Metabolism: Clinical and Experimental

Volumn 65, Issue 3, 2016, Pages 73-83

  Xu, Weifeng ^a,b   Huang, Yujie ^a   Li, Lei ^a   Sun, Zhen ^a   Shen, Yachen ^a   Xing, Jing ^a   Li, Min ^a   Su, Dongming ^a   Liang, Xiubin ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Zhuji People s Hospital   (China)

Author keywords

ENaC regulatory complex; Epithelial sodium channel; Hypertension; Hyperuricemia

Indexed keywords

ALPHA EPITHELIAL SODIUM CHANNEL; AMILORIDE; BENZBROMARONE; BETA ACTIN; BETA EPITHELIAL SODIUM CHANNEL; CHLORIDE; CREATININE; EPITHELIAL SODIUM CHANNEL; GAMMA EPITHELIAL SODIUM CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OTERACIL; POTASSIUM; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM; TUBULIN; UNCLASSIFIED DRUG; URIC ACID; DIURETIC AGENT; IMMEDIATE EARLY PROTEIN; PROTEIN SERINE THREONINE KINASE; SERUM-GLUCOCORTICOID REGULATED KINASE; URICOSURIC AGENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CHLORIDE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; ELEVATED BLOOD PRESSURE; ENZYME PHOSPHORYLATION; FLUID INTAKE; HYPERTENSION; HYPERURICEMIA; IMMUNOHISTOCHEMISTRY; KIDNEY FUNCTION; KIDNEY PARENCHYMA; MALE; NEPHRON; NONHUMAN; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SODIUM BLOOD LEVEL; SODIUM TRANSPORT; SYSTOLIC BLOOD PRESSURE; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; URINE VOLUME; WESTERN BLOTTING; ANIMAL; CELL LINE; COMPLICATION; DRUG EFFECTS; HYPERTENSION, RENAL; KIDNEY; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

AMILORIDE; ANIMALS; BENZBROMARONE; BLOOD PRESSURE; CELL LINE; DIURETICS; EPITHELIAL SODIUM CHANNELS; HYPERTENSION, RENAL; HYPERURICEMIA; IMMEDIATE-EARLY PROTEINS; KIDNEY; MALE; MAP KINASE SIGNALING SYSTEM; MICE; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; URICOSURIC AGENTS;

EID: 84958181598     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2015.10.026     Document Type: Article

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