Designation and development of biomedical Ti alloys with finer biomechanical compatibility in long-term surgical implants

Frontiers of Materials Science

Volumn 8, Issue 3, 2014, Pages 219-229

  Yu, Zhen Tao ^a   Zhang, Ming Hua ^b   Tian, Yu Xing ^a   Cheng, Jun ^a   Ma, Xi Qun ^a   Liu, Han Yuan ^a   Wang, Chang ^a  

^a NORTHWEST INSTITUTE FOR NONFERROUS METAL RESEARCH   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

biomechanical compatibility; biomedical Ti alloys; microstructure; phase transformation; surgical implant

Indexed keywords

EID: 84958114872     PISSN: 2095025X     EISSN: 20950268     Source Type: Journal    
DOI: 10.1007/s11706-014-0254-8     Document Type: Review

References (50)

1. Yu Z T, Zhang M H, Yu S, et al. Analysis of research and development production and application of biomedical Ti alloys materials applied in medical devices of China. China Medical Devices Information, 2012, 18(7): 1–8 (in Chinese)
2. Bothe R T, Beaton L E, Davenport H A. Reaction of bone to multiple metallic implants. Surgery, Gynecology & Obstetrics, 1940, 71(5): 598–602
3. Leventhal G S. Titanium, a metal for surgery. The Journal of Bone and Joint Surgery: American Volume, 1951, 33(2): 473–474
4. Branemark K P, Breine U, Lindstrom J, et al. Intra-osseous auchorage of dental prostheses. Journal of Experimental Studies, 1969, 3: 81–82
5. Branemark P I, Hansson B O, Adell R, et al. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scandinavian Journal of Plastic and Reconstructive Surgery: Supplementum, 1977, 16: 1–132
6. Geetha M, Singh A K, Asokamani R, et al. Ti based biomaterials, the ultimate choice for orthopedic implants: a review. Progress in Materials Science, 2009, 54(3): 397–425
7. Long M, Rack H J. Titanium alloys in total joint replacement — a materials science perspective. Biomaterials, 1998, 19(18): 1621–1639
8. Kuroda D, Niinomi M, Morinaga M, et al. Design and mechanical properties of new β type titanium alloys for implant materials. Materials Science and Engineering A, 1998, 243(1-2): 244–249
9. Davidson J A, Gergette F S. State of the art materials for orthopedic prosthetic devices. Society of Manufacturing Engineers, 1987, 87: 122–126
10. Zwicker R, Buehler K, Mueller R, et al. Titanium’ 1980, Science and Technology, Proceedings of 4th International Conference on Titanium, Kyoto, Japan, 1980, 505–514
11. Semlitsch M, Staub F, Weber H. Titanium-aluminium-niobium alloy, development for biocompatible, high strength surgical implants. Biomedical Technology, 1985, 30(12): 334–339
12. Sumner D R, Galante J O. Determinants of stress shielding: design versus materials versus interface. Clinical Orthopaedics and Related Research, 1992, 274: 202–212
13. Geetha M, Singh A K, Muraleedharan K, et al. Effect of thermomechanical processing on microstructure of a Ti-13Nb-13Zr. Journal of Alloys and Compounds, 2001, 329(1–2): 264–271
14. Yu Z T, Zhang Y F, Yuan S B, et al. Investigation on heat treatment and materials strengthening of near-β Ti4Zr1Sn3-Mo25Nb alloy. Rare Metal Materials and Engineering, 2008, 37(4): 542–545
15. Yu Z T, Zhang Y F, Liu H, et al. Influence and analysis of alloy elements, process and heat treatment on mechanical properties of near-β TiZrMoNb. Rare Metal Materials and Engineering, 2010, 39(10): 1795–1801
16. Hao Y L, Yang R. Ti-Nb-Zr-Sn Ti alloy with nano grain and high strength. Acta Metallurgica Sinica, 2005, 41(11): 1183–1189 (in Chinese)
17. Okazaki Y, Ito Y, Kyo K, et al. Corrosion resistance and corrosion fatigue strength of new titanium alloys for medical implants without Vand Al. Materials Science and Engineering A, 1996, 213(1–2): 138–147
18. Song Y, Xu D S, Yang R, et al. Theoretical study of the effects of alloying elements on the strength and modulus of β-type biotitanium alloys. Materials Science and Engineering A, 1999, 260(1–2): 269–274
19. Wang X Z, Xiao J S, Zhang Z, et al. Research and development on Ti alloy with high elastic modulus and high strength. Acta Metallurgica Sinica, 1999, 35(suppl1): 167–170 (in Chinese)
20. Takahashi E, Sakurai T, Watanabe S, et al. Effect of treatment and Sn content on superelastic in biocompatibility TiNbSn alloys. Materials Transactions, 2002, 43(12): 2978–2983
21. Obbard E G, Hao Y L, Talling R J, et al. The effect of oxygen on α″martensite and superelasticity in Ti-24Nb-4Zr-8Sn. A Acta Materialia, 2011, 59(1): 112–125
22. Niinomi M. Mechanical properties of biomedical titanium alloys. Materials Science and Engineering A, 1998, 243(1–2): 231–236
23. Song Y, Yang R, Li D, et al. Calculation of theoretical strengths and bulk moduli of bcc metals. Physical Review B: Condensed Matter and Materials Physics, 1999, 59(22): 14220–14225
24. Hwang J, Kuramoto S, Furuta T, et al. Phase-stability dependence of plastic deformation behavior in Ti-Nb-Ta-Zr-O alloy. Journal of Materials Engineering and Performance, 2005, 14(6): 747–754
25. Guillemot F, Prima F, Bareille R, et al. Design of new titanium alloys for orthopaedic applications. Medical & Biological Engineering & Computing, 2004, 42(1): 137–141
26. Saito T, Furuta T, Hwang J H, et al. Multifunctional alloys obtained via a dislocation-free plastic deformation mechanism. Science, 2003, 300(5618): 464–467
27. Kent D, Wang G, Yu Z, et al. Strength enhancement of a biomedical titanium alloy through a modified accumulative roll bonding technique. Journal of the Mechanical Behavior of Biomedical Materials, 2011, 4(3): 405–416
28. Kent D, Wang G, Yu Z T, et al. Pseudoelastic behaviour of a β Ti-25Nb-3Zr-3Mo-2Sn alloy. Materials Science and Engineering A, 2010, A527(9): 2246–2252
29. Paladugu M, Kent D, Wang G, et al. Strengthening of cast Ti-25Nb-3Mo-3Zr-2Sn alloy through precipitation of α in two discrete crystallographic orientations. Materials Science and Engineering A, 2010, 527(24–25): 6601–6606
30. Hao Y L, Li S J, Sun S Y, et al. Elastic deformation behaviour of Ti-24Nb-4Zr-7.9Sn for biomedical applications. Acta Biomaterialia, 2007, 3(2): 277–286
31. Yu Z T, Han J Y, Ma X Q, et al. Biological and mechanical compatibility of biomedical titanium alloy materials. Chinese Journal of Tissue Engineering Research, 2013, 17(25): 4707–4714
32. Grosdidier T, Philippe M J. Deformation induced martensite and superelasticity in a β-metastable titanium alloy. Materials Science and Engineering A, 2000, 291(1–2): 218–223
33. Niinomi M. Mechanical biocompatibilities of titanium alloys for biomedical applications. Journal of the Mechanical Behavior of Biomedical Materials, 2008, 1(1): 30–42
34. Yu Z T, Tian Y X, Yu S, et al. Research of novel β-type TLM alloy used in orthopedics. Chinese Journal of Clinical and Basic Orthopaedic Research, 2013, 5(1): 6–13 (in Chinese)
35. Ma X Q, Yu Z T, Niu J L, et al. Phase transformation and mechanical properties of Ti3Zr2Sn3Mo25Nb alloy. Transactions of Nonferrous Metals Society of China, 2010, 20(Special 1): 410–413
36. Leon M J, Evgeny L, Ruslan Z, et al. Nanostructured titaniumbased materials for medical implants: Modeling and development. Materials Science and Engineering R: Reports, 2014, 81: 1–19
37. Kuramoto S, Furuta T, Hwang J H, et al. Plastic deformation in a multifunctional Ti-Nb-Ta-Zr-O alloy. Metallurgical and Materials Transactions A, 2006, 37(3): 657–662
38. Yu Z T, Zhou L, Luo L J, et al. Investigation on mechanical compatibility matching for biomedical titanium alloys. Key Engineering Materials, 2005, 288-289: 595–598
39. Duerig TW, Terlinde G T, Willams J C. Phase transformation and tensile properties of Ti-10V-2Fe-3Al. Metallurgical Transactions A, 1980, 11(12): 1987–1998
40. Couchi C, Fukai H, Hasegawa K. Titanium’98, Proceeding of 9th International Titanium Conference, Xi’an, China, 1998, 129–137
41. Zhou T, Aindow M, Alpay S P, et al. Pseudo-elastic deformation behavior in a Ti/Mo based alloy. Scripta Materialia, 2004, 50(3): 343–348
42. Hanada S, Yoshio T, Nishimura K, et al. Titanium’88, Proceedings of 6th World Conference on Titanium, France, 1988, 105–110
43. Guibert J Ph, Servant C. Titanium’95, Science and Technology, Proceedings of 8th World Conference on Titanium, 1995, 972–979
44. Niinomi M, Nakai M, Hieda J. Development of new metallic alloys for biomedical applications. Acta Biomaterialia, 2012, 8(11): 3888–3903
45. Yu Z T, Zhou L, Niu J L, et al. Titanium’2007, Science and Technology, Proceedings of the 11th World Conference on Titanium, 2007, 1425–1428
46. Ma X Q, Yu Z T, Han Y, et al. In situ scanning electron microscopy observation of deformation and fracture behavior of Ti-3Zr-2Sn-3Mo-25Nb alloy. Rare Metals, 2012, 31(4): 318–322
47. Yu Z T, Zheng Y F, Zhou L, et al. Shape memory effect and superelastic property of a novel Ti-3Zr-2Sn-3Mo-15Nb alloy. Rare Metal Materials and Engineering, 2008, 37(1): 1–5
48. Yu Z T, Zhou L. Influence of martensitic transformation on mechanical compatibility of biomedical β type titanium alloy TLM. Materials Science and Engineering A, 2006, 438–440: 391–394
49. Mow V C, Huiskes R, eds. Basic Orthopaedic Biomechanics and Mechano-Biology (in Chinese, trans. Tang T T, Pei G X, Li X, et al.). 3rd ed. Jinan: Shandong Science & Technology Press, 2009, 115–157 (Original work published 2004)
50. Huang R, Han Y. The effect of surface grain refinement of Ti-25Nb-3Mo-3Zr-2Sn alloy on the osteoblast behavior. Chinese Journal of Clinical and Basic Orthopaedic Research, 2013, 5(1): 28–34 (in Chinese)