Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta- defensin- 2 via toll- like receptor 4 signalling

Cellular Microbiology

Volumn 18, Issue 3, 2016, Pages 424-436

  Sung, Dong Kyung ^b   Chang, Yun Sil ^a,b   Sung, Se In ^a,b   Yoo, Hye Soo ^a,b   Ahn, So Yoon ^a,b   Park, Won Soon ^a,b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Samsung Medical Center   (South Korea)

Author keywords

Acute lung injury; Beta defensin 2; Escherichia coli; Mesenchymal stem cells; Toll like receptor 4

Indexed keywords

BETA DEFENSIN 2; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; BETA DEFENSIN; DEFB4A PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL PNEUMONIA; CONTROLLED STUDY; DOWN REGULATION; ESCHERICHIA COLI; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; MALE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN SECRETION; RECEPTOR UPREGULATION; ANIMAL; ESCHERICHIA COLI INFECTIONS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; INSTITUTE FOR CANCER RESEARCH MOUSE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; PREGNANCY; SECRETION (PROCESS);

ACUTE LUNG INJURY; ANIMALS; BETA-DEFENSINS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE, INBRED ICR; PNEUMONIA, BACTERIAL; PREGNANCY; TOLL-LIKE RECEPTOR 4;

EID: 84958104840     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12522     Document Type: Article

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