Modic Changes and Disc Degeneration Caused by Inoculation of Propionibacterium acnes inside Intervertebral Discs of Rabbits: A Pilot Study

BioMed Research International

Volumn 2016, Issue , 2016, Pages

  Chen, Zhe ^a   Zheng, Yuehuan ^a   Yuan, Ye ^a   Jiao, Yucheng ^a   Xiao, Jiaqi ^a   Zhou, Zezhu ^a   Cao, Peng ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; DISEASE MODEL; GRAM POSITIVE INFECTION; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; MICROBIOLOGY; PATHOLOGY; PROPIONIBACTERIUM ACNES; RABBITS AND HARES;

ANIMALS; DISEASE MODELS, ANIMAL; GRAM-POSITIVE BACTERIAL INFECTIONS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; PROPIONIBACTERIUM ACNES; RABBITS;

EID: 84958093457     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2016/9612437     Document Type: Article

References (27)

1. M. T. Modic and J. S. Ross, "Lumbar degenerative disk disease," Radiology, vol. 245, no. 1, pp. 43-61, 2007.
2. Y.-H. Zhang, C.-Q. Zhao, L.-S. Jiang, X.-D. Chen, and L.-Y. Dai, "Modic changes: a systematic review of the literature," European Spine Journal, vol. 17, no. 10, pp. 1289-1299, 2008.
3. M. T. Modic, P. M. Steinberg, J. S. Ross, T. J. Masaryk, and J. R. Carter, "Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging," Radiology, vol. 166, no. 1, part 1, pp. 193-199, 1988.
4. M. Kuisma, J. Karppinen, J. Niinimäki et al., "Modic changes in endplates of lumbar vertebral bodies: prevalence and association with low back and sciatic pain among middle-aged male workers," Spine, vol. 32, no. 10, pp. 1116-1122, 2007.
5. J. H. Määttä, S. Wadge, A. MacGregor, J. Karppinen, and F. M. Williams, "ISSLS prize winner: vertebral endplate (Modic) change is an independent risk factor for episodes of severe and disabling low back pain," Spine, vol. 40, no. 15, pp. 1187-1193, 2015.
6. A. Stirling, T. Worthington, M. Rafiq, P. A. Lambert, and T. S. J. Elliott, "Association between sciatica and Propionibacterium acnes," The Lancet, vol. 357, no. 9273, pp. 2024-2025, 2001.
7. J. Arndt, Y. P. Charles, C. Koebel, I. Bogorin, and J.-P. Steib, "Bacteriology of degenerated lumbar intervertebral disks," Journal of Spinal Disorders and Techniques, vol. 25, no. 7, pp. E211-E216, 2012.
8. H. B. Albert, P. Lambert, J. Rollason et al., "Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?" European Spine Journal,vol. 22, no. 4, pp. 690-696, 2013.
9. H. B. Albert, P. Kjaer, T. S. Jensen, J. S. Sorensen, T. Bendix, and C. Manniche, "Modic changes, possible causes and relation to low back pain," Medical Hypotheses, vol. 70, no. 2, pp. 361-368, 2008.
10. H. B. Albert, J. S. Sorensen, B. S. Christensen, and C. Manniche, "Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy," European Spine Journal, vol. 22, no. 4, pp. 697-707, 2013.
11. A. Perry and P. Lambert, "Propionibacterium acnes: infection beyond the skin," Expert Review of Anti-Infective Therapy, vol. 9, no. 12, pp. 1149-1156, 2011.
12. A. Carricajo, C. Nuti, E. Aubert et al., "Propionibacterium acnes contamination in lumbar disc surgery," Journal of Hospital Infection, vol. 66, no. 3, pp. 275-277, 2007.
13. J. O'Dowd and A. Casey, "Antibiotics a cure for back pain, a false dawn or a new era?" European Spine Journal, vol. 22, no. 8, pp. 1694-1697, 2013.
14. D. N. Fredricks and D. A. Relman, "Sequence-based identification of microbial pathogens: a reconsideration of Koch's postulates," Clinical Microbiology Reviews, vol. 9, no. 1, pp. 18-33, 1996.
15. R. Koch, "Uber bakteriologische Forschung," in Verhandlung des X Internationalen Medichinischen Congresses, Berlin, 1890, August Hirschwald, Berlin, Germany, 10th International Congress of Medicine, Berlin, Germany, 1891 (German).
16. Z. Zhou, Z. Chen, Y. Zheng et al., "Relationship between annular tear and presence of Propionibacterium acnes in lumbar intervertebral disc," European Spine Journal, vol. 24, no. 11, pp. 2496-2502, 2015.
17. G. Bierry, F. Jehl, G. Prévost et al., "Percutaneous inoculated rabbit model of intervertebral disc space infection: magnetic resonance imaging features with pathological correlation," Joint Bone Spine, vol. 75, no. 4, pp. 465-470, 2008.
18. B. Li, Z. Dong, Y. Wu et al., "between lumbar disc degeneration and Propionibacterium acnes infection: clinical research and preliminary exploration of animal experiment," Spine, 2015.
19. S. H. Hong, J.-Y. Choi, J. W. Lee, N. R. Kim, J.-A. Choi, and H. S. Kang, "MR imaging assessment of the spine: infection or an imitation?" Radiographics, vol. 29, no. 2, pp. 599-612, 2009.
20. J. A. T. Dunbar, J. A. T. Sandoe, A. S. Rao, D. W. Crimmins, W. Baig, and J. J. Rankine, "The MRI appearances of early vertebral osteomyelitis and discitis," Clinical Radiology, vol. 65, no. 12, pp. 974-981, 2010.
21. A. S. Evans, "Causation and disease: the Henle-Koch postulates revisited," Yale Journal of Biology and Medicine, vol. 49, no. 2, pp. 175-195, 1976.
22. J. S. Butler, M. J. Shelly, M. Timlin, W. G. Powderly, and J. M. O'Byrne, "Nontuberculous pyogenic spinal infection in adults: a 12-year experience from a tertiary referral center," Spine, vol. 31, no. 23, pp. 2695-2700, 2006.
23. I. Uçkay, A. Dinh, L. Vauthey et al., "Spondylodiscitis due to Propionibacterium acnes: report of twenty-nine cases and a review of the literature," Clinical Microbiology and Infection, vol. 16, no. 4, pp. 353-358, 2010.
24. M. D. Farrar and E. Ingham, "Acne: inflammation," Clinics in Dermatology, vol. 22, no. 5, pp. 380-384, 2004.
25. S. Ohtori, G. Inoue, T. Ito et al., "Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back pain and modic type 1 or type 2 changes on MRI," Spine, vol. 31, no. 9, pp. 1026-1031, 2006.
26. M. V. Risbud and I. M. Shapiro, "Role of cytokines in intervertebral disc degeneration: pain and disc content," Nature Reviews Rheumatology, vol. 10, no. 1, pp. 44-56, 2014.
27. D. M. Elliott, C. S. Yerramalli, J. C. Beckstein, J. I. Boxberger, W. Johannessen, and E. J. Vresilovic, "The effect of relative needle diameter in puncture and sham injection animal models of degeneration," Spine, vol. 33, no. 6, pp. 588-596, 2008.