Shared molecular mechanisms in Alzheimer's disease and amyotrophic lateral sclerosis: Neurofilament-dependent transport of sAPP, FUS, TDP-43 and SOD1, with endoplasmic reticulum-like tubules

Neurodegenerative Diseases

Volumn 16, Issue 1-2, 2016, Pages 55-61

  Muresan, Virgil ^a   Muresan, Zoia Ladescu ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Amyotrophic lateral sclerosis; Converging mechanisms of neurodegenerative diseases; Endoplasmic reticulum; FUS; Motor neurons; Neurofilaments; SOD1; TDP 43

Indexed keywords

AMYLOID PRECURSOR PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; FUSED IN SARCOMA PROTEIN; SAPP PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; APP PROTEIN, HUMAN; DNA BINDING PROTEIN; FUS PROTEIN, HUMAN; MYELIN PROTEIN; PERIPHERIN; PROTEIN NOGO; PRPH PROTEIN, HUMAN; RNA BINDING PROTEIN FUS; RTN4 PROTEIN, HUMAN; SOD1 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE; TDP-43 PROTEIN, HUMAN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN CELL CULTURE; BRAIN NERVE CELL; BRAIN STEM; CONFERENCE PAPER; ENDOPLASMIC RETICULUM MEMBRANE; GENE MUTATION; HUMAN; INTRACELLULAR TRANSPORT; NEUROFILAMENT; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN TRANSPORT; CELL LINE; ENDOPLASMIC RETICULUM; GROWTH CONE; INTERMEDIATE FILAMENT; METABOLISM; NERVE CELL; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYOTROPHIC LATERAL SCLEROSIS; BIOLOGICAL TRANSPORT; BRAIN STEM; CELL LINE; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; GROWTH CONES; HUMANS; INTERMEDIATE FILAMENTS; MYELIN PROTEINS; NEURONS; NOGO PROTEINS; PERIPHERINS; RNA-BINDING PROTEIN FUS; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE-1;

EID: 84958044118     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000439256     Document Type: Conference Paper

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